메뉴 건너뛰기




Volumn 15, Issue 5, 2009, Pages 279-285

Cryopreservation of porcine oocytes: Recent advances

Author keywords

Cryoinjury; Cryopreservation; Cryoprotectant; Porcine oocytes; Taxol

Indexed keywords

CYTOCHALASIN B; DIMETHYL SULFOXIDE; ETHYLENE GLYCOL; PACLITAXEL; RUTHENIUM RED; STABILIZING AGENT; CRYOPROTECTIVE AGENT; LIPID; TUBULIN MODULATOR;

EID: 64549151565     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gap016     Document Type: Review
Times cited : (71)

References (48)
  • 2
    • 0025163167 scopus 로고
    • Freeze-thaw-induced changes of the zona pellucida explains decreased rate of fertilization in frozen-thawed mouse oocytes
    • Carroll J, Depyere H, Matthews CD. Freeze-thaw-induced changes of the zona pellucida explains decreased rate of fertilization in frozen-thawed mouse oocytes. J Reprod Fertil 1990;90:547-553.
    • (1990) J Reprod Fertil , vol.90 , pp. 547-553
    • Carroll, J.1    Depyere, H.2    Matthews, C.D.3
  • 3
    • 0022611046 scopus 로고
    • Pregnancy after human oocyte cryopreservation
    • Chen C. Pregnancy after human oocyte cryopreservation. Lancet 1986; 1:884-886.
    • (1986) Lancet , vol.1 , pp. 884-886
    • Chen, C.1
  • 4
    • 0031873752 scopus 로고    scopus 로고
    • The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review
    • Csermely P, Schnaider T, Soti C, Prohaszka Z, Nardai G. The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review. Pharmacol Ther 1998; 79 129-168.
    • (1998) Pharmacol Ther , vol.79 , pp. 129-168
    • Csermely, P.1    Schnaider, T.2    Soti, C.3    Prohaszka, Z.4    Nardai, G.5
  • 5
    • 0035506576 scopus 로고    scopus 로고
    • Cryopreservation of swine embryos: A chilly past with a vitrifying future
    • Dobrinsy JR. Cryopreservation of swine embryos: A chilly past with a vitrifying future. Theriogenology 2001;56:1333-1344.
    • (2001) Theriogenology , vol.56 , pp. 1333-1344
    • Dobrinsy, J.R.1
  • 7
    • 34247614106 scopus 로고    scopus 로고
    • Heat-shock proteins modulate the incidence of apoptosis and oxidative stress in preimplantation mouse embryos
    • Esfandiari N, Falcone T, Goldberg JM, Agarwal A, Sharma RK. Heat-shock proteins modulate the incidence of apoptosis and oxidative stress in preimplantation mouse embryos. Fertil Steril 2007;87 1214-1217.
    • (2007) Fertil Steril , vol.87 , pp. 1214-1217
    • Esfandiari, N.1    Falcone, T.2    Goldberg, J.M.3    Agarwal, A.4    Sharma, R.K.5
  • 8
    • 64549143606 scopus 로고    scopus 로고
    • Positive effects of Taxol pretreatment on morphology, distribution and ultrastructure of mitochondria and lipid droplets in vitrification of in vitro matured porcine oocytes
    • doi:10.1016/j.anireprosci.2008.12.002
    • Fu XW, Shi WQ, Zhang QJ, Zhao XM, Yan CL, Hou YP, Zhou GB, Fan ZQ, Suo L, Zhu SE. Positive effects of Taxol pretreatment on morphology, distribution and ultrastructure of mitochondria and lipid droplets in vitrification of in vitro matured porcine oocytes. Anim Reprod Sci 2009;doi:10.1016/j.anireprosci.2008.12.002.
    • (2009) Anim Reprod Sci
    • Fu, X.W.1    Shi, W.Q.2    Zhang, Q.J.3    Zhao, X.M.4    Yan, C.L.5    Hou, Y.P.6    Zhou, G.B.7    Fan, Z.Q.8    Suo, L.9    Zhu, S.E.10
  • 9
    • 10944240873 scopus 로고    scopus 로고
    • Developmental capacity of vitrified immature porcine oocytes following ICSI: Effects of cytochalasin B and cryoprotectants
    • Fujihira T, Kishida R, Fukui Y. Developmental capacity of vitrified immature porcine oocytes following ICSI: Effects of cytochalasin B and cryoprotectants. Cryobiology 2004;49:286-290.
    • (2004) Cryobiology , vol.49 , pp. 286-290
    • Fujihira, T.1    Kishida, R.2    Fukui, Y.3
  • 10
    • 28744451930 scopus 로고    scopus 로고
    • Relationship between equilibration times and the presence of cumulus cells, and effect of taxol treatment for vitrification of in vitro matured porcine oocytes
    • Fujihira T, Nagai H, Fukui Y. Relationship between equilibration times and the presence of cumulus cells, and effect of taxol treatment for vitrification of in vitro matured porcine oocytes. Cryobiology 2005; 51:339-343.
    • (2005) Cryobiology , vol.51 , pp. 339-343
    • Fujihira, T.1    Nagai, H.2    Fukui, Y.3
  • 11
    • 0026901675 scopus 로고
    • In vitro fertilization and development of frozen-thawed bovine oocytes
    • Fuku E, Kojima T, Shioya Y, Marcus GJ, Downey BR. In vitro fertilization and development of frozen-thawed bovine oocytes. Cryobiology 1992; 29:485-492.
    • (1992) Cryobiology , vol.29 , pp. 485-492
    • Fuku, E.1    Kojima, T.2    Shioya, Y.3    Marcus, G.J.4    Downey, B.R.5
  • 12
    • 33845326121 scopus 로고    scopus 로고
    • Cryopreservation of immature and in vitro matured porcine oocytes by solid surface vitrification
    • Gupta MK, Uhm SJ, Lee HT. Cryopreservation of immature and in vitro matured porcine oocytes by solid surface vitrification. Theriogenology 2007;67:238-248.
    • (2007) Theriogenology , vol.67 , pp. 238-248
    • Gupta, M.K.1    Uhm, S.J.2    Lee, H.T.3
  • 13
    • 17444376822 scopus 로고    scopus 로고
    • Extrusion and removal of lipid from the cytoplasm of porcine oocytes at the germinal vesicle stage: Centrifugation under hypertonic conditions influences vitrification
    • Hara K, Abe Y, Kumada N, Aono N, Kobayashi J, Matsumoto H, Sasada H, Sato E. Extrusion and removal of lipid from the cytoplasm of porcine oocytes at the germinal vesicle stage: Centrifugation under hypertonic conditions influences vitrification. Cryobiology 2005; 50 216-222.
    • (2005) Cryobiology , vol.50 , pp. 216-222
    • Hara, K.1    Abe, Y.2    Kumada, N.3    Aono, N.4    Kobayashi, J.5    Matsumoto, H.6    Sasada, H.7    Sato, E.8
  • 14
    • 0001095933 scopus 로고
    • Pregnancies following transfer of equine embryos cryopreserved by vitrification
    • Hochi S, Fujimoto T, Braun J, Oguri N. Pregnancies following transfer of equine embryos cryopreserved by vitrification. Theriogenology 1994; 42:483-488.
    • (1994) Theriogenology , vol.42 , pp. 483-488
    • Hochi, S.1    Fujimoto, T.2    Braun, J.3    Oguri, N.4
  • 15
    • 63249089132 scopus 로고    scopus 로고
    • Oocyte vitrification - women's emancipation set in stone
    • doi:10.1016/ j.fertnstert.2008.02.127
    • Homburg R, van VF, Silber SJ. Oocyte vitrification - women's emancipation set in stone. Fertil Steril 2008, doi:10.1016/ j.fertnstert.2008.02.127.
    • Fertil Steril , vol.2008
    • Homburg, R.V.V.1    Silber, S.J.2
  • 16
    • 27644449255 scopus 로고    scopus 로고
    • Bovine oocytes vitrified by the open pulled straw method and used for somatic cell cloning supported development to term
    • Hou YP, Dai YP, Zhu SE, Zhu HB, Wu TY, Gong GC, Wang HP, Wang LL, Liu Y, Li R et al. Bovine oocytes vitrified by the open pulled straw method and used for somatic cell cloning supported development to term. Theriogenology 2005;64:1381-1391.
    • (2005) Theriogenology , vol.64 , pp. 1381-1391
    • Hou, Y.P.1    Dai, Y.P.2    Zhu, S.E.3    Zhu, H.B.4    Wu, T.Y.5    Gong, G.C.6    Wang, H.P.7    Wang, L.L.8    Liu, Y.9    Li, R.10
  • 18
    • 0032066114 scopus 로고    scopus 로고
    • Vitrification of immature porcine oocytes: Effects of lipid droplets, temperature, cytoskeleton, and addition and removal of cryoprotectant
    • Isachenko V, Soler C, Isachenko E, Perez-Sanchez F, Grishchenko V. Vitrification of immature porcine oocytes: Effects of lipid droplets, temperature, cytoskeleton, and addition and removal of cryoprotectant. Cryobiology 1998;36:250-253.
    • (1998) Cryobiology , vol.36 , pp. 250-253
    • Isachenko, V.1    Soler, C.2    Isachenko, E.3    Perez-Sanchez, F.4    Grishchenko, V.5
  • 19
    • 0032478208 scopus 로고    scopus 로고
    • Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation
    • Kaarniranta K, Elo M, Sironen R, Lammi MJ, Goldring MB, Eriksson JE, Sistonen L, Helminen HJ. Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation. Proc Natl Acad Sci USA 1998;95:2319-2324.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2319-2324
    • Kaarniranta, K.1    Elo, M.2    Sironen, R.3    Lammi, M.J.4    Goldring, M.B.5    Eriksson, J.E.6    Sistonen, L.7    Helminen, H.J.8
  • 20
    • 0000429832 scopus 로고
    • Effects of high-hydrostatic pressure processes on food safety and quality
    • Knorr D. Effects of high-hydrostatic pressure processes on food safety and quality. Food Technol 1993;47:156-161.
    • (1993) Food Technol , vol.47 , pp. 156-161
    • Knorr, D.1
  • 21
    • 0032802652 scopus 로고    scopus 로고
    • Sugars exert a major influence on the vitrification properties of ethylene glycol-based solutions and have low toxicity to embryos and oocytes
    • Kuleshova LL, MacFarlane DR, Trounson AO, Shaw JM. Sugars exert a major influence on the vitrification properties of ethylene glycol-based solutions and have low toxicity to embryos and oocytes. Cryobiology 1999;38:119-130.
    • (1999) Cryobiology , vol.38 , pp. 119-130
    • Kuleshova, L.L.1    MacFarlane, D.R.2    Trounson, A.O.3    Shaw, J.M.4
  • 22
    • 0038302675 scopus 로고    scopus 로고
    • Effects of cooling on meiotic spindle structure and chromosome alignment within in vitro matured porcine oocytes
    • Liu RH, Sun QY, Li YH, Jiao LH, Wang WH. Effects of cooling on meiotic spindle structure and chromosome alignment within in vitro matured porcine oocytes. Mol Reprod Dev 2003a;65:212-218.
    • (2003) Mol Reprod Dev , vol.65 , pp. 212-218
    • Liu, R.H.1    Sun, Q.Y.2    Li, Y.H.3    Jiao, L.H.4    Wang, W.H.5
  • 23
    • 1842684308 scopus 로고    scopus 로고
    • Maturation of porcine oocytes after cooling at the germinal vesicle stage
    • Liu RH, Sun QY, Li YH, Jiao LH, Wang WH. Maturation of porcine oocytes after cooling at the germinal vesicle stage. Zygote 2003b; 11 299-305.
    • (2003) Zygote , vol.11 , pp. 299-305
    • Liu, R.H.1    Sun, Q.Y.2    Li, Y.H.3    Jiao, L.H.4    Wang, W.H.5
  • 24
    • 34248155745 scopus 로고    scopus 로고
    • The effect of osmotic stress on the cell volume, metaphase II spindle and developmental potential of in vitro matured porcine oocytes
    • Mullen SF, Rosenbaum M, Critser JK. The effect of osmotic stress on the cell volume, metaphase II spindle and developmental potential of in vitro matured porcine oocytes. Cryobiology 2007;54 281-289.
    • (2007) Cryobiology , vol.54 , pp. 281-289
    • Mullen, S.F.1    Rosenbaum, M.2    Critser, J.K.3
  • 25
    • 56449114692 scopus 로고    scopus 로고
    • Improvement in the in vitro maturation rate of porcine oocytes vitrified at the germinal vesicle stage by treatment with a mitochondrial permeability transition inhibitor
    • doi: 10.1016/j.cryobiol.2008. 09.008
    • Nakagawa S, Yoneda A, Hayakawa K, Watanabe T. Improvement in the in vitro maturation rate of porcine oocytes vitrified at the germinal vesicle stage by treatment with a mitochondrial permeability transition inhibitor. Cryobiology 2008;doi: 10.1016/j.cryobiol.2008. 09.008.
    • (2008) Cryobiology
    • Nakagawa, S.1    Yoneda, A.2    Hayakawa, K.3    Watanabe, T.4
  • 27
    • 20544475962 scopus 로고    scopus 로고
    • Effects of partial removal of cytoplasmic lipid on survival of vitrified germinal vesicle stage pig oocytes
    • Park KE, Kwon IK, Han MS, Niwa K. Effects of partial removal of cytoplasmic lipid on survival of vitrified germinal vesicle stage pig oocytes. J Reprod Dev 2005;51:151-160.
    • (2005) J Reprod Dev , vol.51 , pp. 151-160
    • Park, K.E.1    Kwon, I.K.2    Han, M.S.3    Niwa, K.4
  • 28
    • 56749096477 scopus 로고    scopus 로고
    • Animal oocyte and embryo cryopreservation
    • doi:10.1007/s10561-008-9075-2
    • Pereira RM, Marques CC. Animal oocyte and embryo cryopreservation. Cell Tissue Bank 2008;doi:10.1007/s10561-008-9075-2.
    • (2008) Cell Tissue Bank
    • Pereira, R.M.1    Marques, C.C.2
  • 29
    • 41549116743 scopus 로고    scopus 로고
    • Increased stress tolerance of matured pig oocytes after high hydrostatic pressure treatment
    • Pribenszky C, Du Y, Molnar M, Harnos A, Vajta G. Increased stress tolerance of matured pig oocytes after high hydrostatic pressure treatment. Anim Reprod Sci 2008;106:200-207.
    • (2008) Anim Reprod Sci , vol.106 , pp. 200-207
    • Pribenszky, C.1    Du, Y.2    Molnar, M.3    Harnos, A.4    Vajta, G.5
  • 30
    • 0021931348 scopus 로고
    • Ice-free cryopreservation of mouse embryos at - 196 degrees C by vitrification
    • Rall WF, Fahy GM. Ice-free cryopreservation of mouse embryos at - 196 degrees C by vitrification. Nature 1985;313:573-575.
    • (1985) Nature , vol.313 , pp. 573-575
    • Rall, W.F.1    Fahy, G.M.2
  • 31
    • 10944231212 scopus 로고    scopus 로고
    • Vitrification of immature and in vitro matured pig oocytes: Study of distribution of chromosomes, microtubules, and actin microfilaments
    • Rojas C, Palomo MJ, Albarracin JL, Mogas T. Vitrification of immature and in vitro matured pig oocytes: Study of distribution of chromosomes, microtubules, and actin microfilaments. Cryobiology 2004;49: 211-220.
    • (2004) Cryobiology , vol.49 , pp. 211-220
    • Rojas, C.1    Palomo, M.J.2    Albarracin, J.L.3    Mogas, T.4
  • 32
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by taxol. Nature 1979;277:665-667.
    • (1979) Nature , vol.277 , pp. 665-667
    • Schiff, P.B.1    Fant, J.2    Horwitz, S.B.3
  • 33
    • 0031262509 scopus 로고    scopus 로고
    • Vitrification properties of solutions of ethylene glycol in saline containing PVP, Ficoll, or dextran
    • Shaw JM, Kuleshova LL, MacFarlane DR, Trounson AO. Vitrification properties of solutions of ethylene glycol in saline containing PVP, Ficoll, or dextran. Cryobiology 1997;35:219-229.
    • (1997) Cryobiology , vol.35 , pp. 219-229
    • Shaw, J.M.1    Kuleshova, L.L.2    MacFarlane, D.R.3    Trounson, A.O.4
  • 34
    • 33646250897 scopus 로고    scopus 로고
    • Improved development by Taxol pretreatment after vitrification of in vitro matured porcine oocytes
    • Shi WQ, Zhu SE, Zhang D, Wang WH, Tang GL, Hou YP, Tian SJ. Improved development by Taxol pretreatment after vitrification of in vitro matured porcine oocytes. Reproduction 2006;131: 795-804.
    • (2006) Reproduction , vol.131 , pp. 795-804
    • Shi, W.Q.1    Zhu, S.E.2    Zhang, D.3    Wang, W.H.4    Tang, G.L.5    Hou, Y.P.6    Tian, S.J.7
  • 36
    • 33745463659 scopus 로고    scopus 로고
    • Development to the blastocyst stage of parthenogenetically activated in vitro matured porcine oocytes after solid surface vitrification (SSV)
    • Somfai T, Dinnyes A, Sage D, Marosan M, Carnwath JW, Ozawa M, Kikuchi K, Niemann H. Development to the blastocyst stage of parthenogenetically activated in vitro matured porcine oocytes after solid surface vitrification (SSV). Theriogenology 2006;66: 415-422.
    • (2006) Theriogenology , vol.66 , pp. 415-422
    • Somfai, T.1    Dinnyes, A.2    Sage, D.3    Marosan, M.4    Carnwath, J.W.5    Ozawa, M.6    Kikuchi, K.7    Niemann, H.8
  • 37
    • 46349108181 scopus 로고    scopus 로고
    • Effect of centrifugation treatment before vitrification on the viability of porcine mature oocytes and zygotes produced in vitro
    • Somfai T, Kashiwazaki N, Ozawa M, Nakai M, Maedomari M, Noguchi J, Kaneko H, Nagai T, Kikuchi K. Effect of centrifugation treatment before vitrification on the viability of porcine mature oocytes and zygotes produced in vitro. J Reprod Dev 2008a;54:149-155.
    • (2008) J Reprod Dev , vol.54 , pp. 149-155
    • Somfai, T.1    Kashiwazaki, N.2    Ozawa, M.3    Nakai, M.4    Maedomari, M.5    Noguchi, J.6    Kaneko, H.7    Nagai, T.8    Kikuchi, K.9
  • 39
    • 0035157745 scopus 로고    scopus 로고
    • Microtubule assembly after treatment of pig oocytes with taxol: Correlation with chromosomes, gamma-tubulin, and MAP kinase
    • Sun QY, Lai L, Wu GM, Park KW, Day BN, Prather RS, Schatten H. Microtubule assembly after treatment of pig oocytes with taxol: correlation with chromosomes, gamma-tubulin, and MAP kinase. Mol Reprod Dev 2001a;60:481-490.
    • (2001) Mol Reprod Dev , vol.60 , pp. 481-490
    • Sun, Q.Y.1    Lai, L.2    Wu, G.M.3    Park, K.W.4    Day, B.N.5    Prather, R.S.6    Schatten, H.7
  • 40
    • 0034912353 scopus 로고    scopus 로고
    • Translocation of active mitochondria during pig oocyte maturation, fertilization and early embryo development in vitro
    • Sun QY, Wu GM, Lai LX, Park KW, Day BN, Prather RS, Schatten H. Translocation of active mitochondria during pig oocyte maturation, fertilization and early embryo development in vitro. Reproduction 2001b;122:155-163.
    • (2001) Reproduction , vol.122 , pp. 155-163
    • Sun, Q.Y.1    Wu, G.M.2    Lai, L.X.3    Park, K.W.4    Day, B.N.5    Prather, R.S.6    Schatten, H.7
  • 41
    • 34547110157 scopus 로고    scopus 로고
    • Vitrification solution containing DMSO and EG can induce parthenogenetic activation of in vitro matured ovine oocytes and decrease sperm penetration
    • Tian SJ, Yan CL, Yang HX, Zhou GB, Yang ZQ, Zhu SE. Vitrification solution containing DMSO and EG can induce parthenogenetic activation of in vitro matured ovine oocytes and decrease sperm penetration. Anim Reprod Sci 2007;101:365-371.
    • (2007) Anim Reprod Sci , vol.101 , pp. 365-371
    • Tian, S.J.1    Yan, C.L.2    Yang, H.X.3    Zhou, G.B.4    Yang, Z.Q.5    Zhu, S.E.6
  • 42
    • 33745029098 scopus 로고    scopus 로고
    • Are programmable freezers still needed in the embryo laboratory? Review on vitrification
    • Vajta G, Nagy ZP. Are programmable freezers still needed in the embryo laboratory? Review on vitrification. Reprod Biomed Online 2006; 12:779-796.
    • (2006) Reprod Biomed Online , vol.12 , pp. 779-796
    • Vajta, G.1    Nagy, Z.P.2
  • 43
    • 0025852117 scopus 로고
    • Microtubule mediation of cytoplasmic and nuclear maturation during the early stages of resumed meiosis in cultured mouse oocytes
    • Van Blerkom J. Microtubule mediation of cytoplasmic and nuclear maturation during the early stages of resumed meiosis in cultured mouse oocytes. Proc Natl Acad Sci USA 1991;88:5031-5035.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5031-5035
    • Van Blerkom, J.1
  • 44
    • 30944468328 scopus 로고    scopus 로고
    • Effect of open pulled straw (OPS) vitrification on the fertilisation rate and developmental competence of porcine oocytes
    • Varga E, Gardon JC, Papp AB. Effect of open pulled straw (OPS) vitrification on the fertilisation rate and developmental competence of porcine oocytes. Acta Vet Hung 2006;54:107-116.
    • (2006) Acta Vet Hung , vol.54 , pp. 107-116
    • Varga, E.1    Gardon, J.C.2    Papp, A.B.3
  • 45
    • 0034102371 scopus 로고    scopus 로고
    • Polymerization of nonfilamentous actin into microfilaments is an important process for porcine oocyte maturation and early embryo development
    • Wang WH, Abeydeera LR, Prather RS, Day BN. Polymerization of nonfilamentous actin into microfilaments is an important process for porcine oocyte maturation and early embryo development. Biol Reprod 2000;62:1177-1183.
    • (2000) Biol Reprod , vol.62 , pp. 1177-1183
    • Wang, W.H.1    Abeydeera, L.R.2    Prather, R.S.3    Day, B.N.4
  • 46
    • 0017324260 scopus 로고
    • Fertilization in vitro and development to term of unfertilized mouse oocytes previously stored at -196 degree C
    • Whittingham DG. Fertilization in vitro and development to term of unfertilized mouse oocytes previously stored at -196 degree C. J Reprod Fertil 1977;49:89-94.
    • (1977) J Reprod Fertil , vol.49 , pp. 89-94
    • Whittingham, D.G.1
  • 47
    • 0015526251 scopus 로고
    • Survival of mouse embryos frozen to -196 degrees and -269 degrees C
    • Whittingham DG, Leibo SP, Mazur P. Survival of mouse embryos frozen to -196 degrees and -269 degrees C. Science 1972;178:411-414.
    • (1972) Science , vol.178 , pp. 411-414
    • Whittingham, D.G.1    Leibo, S.P.2    Mazur, P.3
  • 48
    • 33748865904 scopus 로고    scopus 로고
    • Effects of cryopreservation on the developmental competence, ultrastructure and cytoskeletal structure of porcine oocytes
    • Wu C, Rui R, Dai J, Zhang C, Ju S, Xie B, Lu X, Zheng X. Effects of cryopreservation on the developmental competence, ultrastructure and cytoskeletal structure of porcine oocytes. Mol Reprod Dev 2006; 73:1454-1462.
    • (2006) Mol Reprod Dev , vol.73 , pp. 1454-1462
    • Wu, C.1    Rui, R.2    Dai, J.3    Zhang, C.4    Ju, S.5    Xie, B.6    Lu, X.7    Zheng, X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.