Design and characterization of a microfluidic packed bed system for protein breakthrough and dynamic binding capacity determination

Biotechnology Progress

Volumn 25, Issue 1, 2009, Pages 277-285

  Shapiro, Michael S ^a   Haswell, Steve J ^b   Lye, Gary J ^a   Bracewell, Daniel G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF HULL   (United Kingdom)

Author keywords

Ion exchange; Microfluidic; Protein breakthrough

Indexed keywords

ADSORPTION PROFILES; BIO-PHARMACEUTICAL INDUSTRIES; BREAK THROUGH CURVES; CARTESIAN GEOMETRIES; CHROMATOGRAPHY COLUMNS; CIRCULAR CROSS SECTIONS; CURRENT PRACTICES; DYNAMIC BINDING CAPACITIES; FABRICATION TECHNIQUES; GLASS CHIPS; ION EXCHANGE CHROMATOGRAPHIES; ISOCRATIC; ISOTROPIC ETCHINGS; LABELED PROTEINS; MEAN DIAMETERS; MICROCOLUMN; MICROFLUIDIC PROCESS; MICROSCOPIC TECHNIQUES; MOBILE-PHASE VELOCITIES; NARROW CHANNELS; POROUS AGAROSE BEADS; PROOF OF PRINCIPLES; PROTEIN BINDINGS; STANDARD VALUES; VOIDAGE;

ADSORPTION; AGGLOMERATION; BIOCHEMISTRY; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; CONFOCAL MICROSCOPY; ION CHROMATOGRAPHY; ION EXCHANGERS; IONS; PACKED BEDS; POLYDISPERSITY; RESINS;

ION EXCHANGE;

PROTEIN;

ARTICLE; CHEMISTRY; CONFOCAL MICROSCOPY; INSTRUMENTATION; ION EXCHANGE CHROMATOGRAPHY; METHODOLOGY; MICROFLUIDICS; THERMODYNAMICS;

CHROMATOGRAPHY, ION EXCHANGE; MICROFLUIDICS; MICROSCOPY, CONFOCAL; PROTEINS; THERMODYNAMICS;

EID: 64549104303     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1002/btpr.99     Document Type: Article

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