Mechanically interlocked calix[4]arene dimers display reversible bond breakage under force

Nature Nanotechnology

Volumn 4, Issue 4, 2009, Pages 225-229

  Janke, Matthias ^a   Rudzevich, Yuliya ^a   Molokanova, Olena ^a   Metzroth, Thorsten ^a   Mey, Ingo ^a   Diezemann, Gregor ^a   Marszalek, Piotr E ^b   Gauss, Jürgen ^a   Böhmer, Volker ^a   Janshoff, Andreas ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b Duke University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN; MOLECULAR DYNAMICS; MOLECULES; NANOCAPSULES; STATISTICAL MECHANICS; STOCHASTIC SYSTEMS;

ENERGY LANDSCAPE; EXPERIMENTAL EVIDENCE; FUNDAMENTAL THEORY; INTERMEDIATE STATE; MOLECULAR DESIGN; MOLECULAR DYNAMICS SIMULATIONS; NANOSCOPIC SYSTEMS; THERMAL FLUCTUATIONS;

DIMERS;

CALIXARENE; CALIX[4]ARENE DIMER; CATENANE; DNA; RIBOZYME; RNA; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; DYNAMIC FORCE SPECTROSCOPY; HYDROGEN BOND; MOLECULAR DYNAMICS; OLIGOMERIZATION; PRIORITY JOURNAL; SPECTROSCOPY; STOCHASTIC MODEL; SUPRAMOLECULAR CHEMISTRY; SYNTHESIS; THERMODYNAMICS;

EID: 64449085129     PISSN: 17483387     EISSN: 17483395     Source Type: Journal    
DOI: 10.1038/nnano.2008.416     Document Type: Article

References (30)

1. Bustamante, C, Liphardt, J. & Ritort, F. The nonequilibrium thermodynamics of small systems. Physics Today 58, 43-48 (2005).
2. Balzani, V., Credi, A., Raymo, F. M. & Stoddart, J. F. Artificial molecular machines. Angew. Chem. Int. Ed. 39, 3349-3391 (2000).
3. Liphardt, J., Onoa, B., Smith, S., Tinoco, I. J. & Bustamante, C. Reversible unfolding of single RNA molecules by mechanical force. Science 292, 733-737(2001).
4. Balzani, V. et al. Autonomous artificial nanomotor powered by sunlight. Proc. Natl Acad. Soc. USA 103, 1178-1183 (2006).
5. Rvans, D. J. & Searles, D. J. The fluctuation theorem. Adv. Phys. 51, 1529-1585 (2002).
6. Jarzynski, C. Nonequilibrium equality for free energy differences. Phys. Rev. Lett.78,2690-2693 (1997).
7. Crooks, G. R. Rntropy production fluctuation theorem and the nonequilibrium work relation for free energy differences. Phys. Rev. E 60, 2721 -2726 (1999).
8. Jarzynski, C. Comparison of far-from-equilibrium work relations. Compt. Rend. Phys. 8, 495-506 (2007).
9. Hoh, J. H., Cleveland, J. P., Prater, C. B., Revel, J. P. & Hansma, P. K. Quantized adhesion detected with the atomic force microscope. J. Am. Chem. Soc. 114, 4917-4918 (1992).
10. Stark, R. W. Getting a feeling for the nanoworld. Nature Nanotech. 2, 461-462(2007).
11. Muller, D. J. & Dufrene, Y. F. Atomic force microscopy as a multifunctional molecular toolbox in nanobiotechnology. Nature Nanotech. 3, 261 -269 (2008).
12. Hickenboth, C. R. et al. Biasing reaction pathways with mechanical force. Nature446,423-427(2007).
13. Weizmann, Y., Braunschweig, A. B., Wilner, O. I., Cheglakov, Z. & Willner, I. A polycatenated DNA scaffold for the one-step assembly of hierarchical nanostructures. Proc. Natl Acad. Soc. USA 105, 5289-5294 (2008).
14. Williams, P. M. et al. Hidden complexity in the mechanical properties of titin. Nature 422, 446-449 (2003).
15. Fisher, T. E., Marszalek, P. E. & Fernandez, J. M. Stretching single molecules into novel conformations using the atomic force microscope. Nat. Struct. Biol. 7, 719-724(2000).
16. Eckel, R., Ros, R., Decker, B., Mattay, J. & Anselmetti, D. Supramolecular chemistry at the single molecule level. Angew. Chem. Int. Ed. 44, 484-488(2005).
17. Schonherr, H. et al. Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy. J. Am. Chem. Soc. 122, 4963-4967(2000).
18. Manosas, M., Collin, D. & Ritort, F. Force-dependent fragility in RNA hairpins. Phys. Rev. Lett. 96, 218301 (2006).
19. Liphardt, J., Dumont, S., Smith, S. B., Tinoco, I. J. & Bustamante, C. Equilibrium information from nonequilibrium measurements in an experimental test of Jarzynski's equality. Science 296, 1832-1835 (2002).
20. Lee, G. et al. Nanospring behaviour of ankyrin repeats. Nature 440, 246-249(2006).
21. Vysotsky, M. O., Bolte, M., Thondorf, I. & Bohmer, V. Newmolecular topologies by fourfold metathesis reactions within a hydrogen-bonded calix[4]arene dimer. Chem. Eur. J. 9, 3375-3382 (2003).
22. Rief, M., Gautel, M., Oesterhelt, F., Fernandez, J. M. & Gaub, H. E. Reversible unfolding of individual titin immunoglobulin domains by AFM. Science 276, 1109-1112(1997).
23. Schlierf, M. & Rief, M. Temperature softening of a protein in single-molecule experiments. J. Mol. Biol. 354, 497-503 (2005).
24. Onoa, B. et al. Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science 299, 1892-1895 (2003).
25. van der Spoel, D. et al. GROMACS: Fast, flexible and free. J. Comp. Chem. 26, 1701-1718(2005).
26. Marszalek, P. E. et al. Mechanical unfolding intermediates in titin modules. Nature 402, 100-103 (1999).
27. Merkel, R., Nassoy, P., Leung, A., Ritchie, K. & Evans, E. Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy. Nature 397, 50-53 (1999).
28. Dudko, O. K., Hummer, G. & Szabo, A. Intrinsic rates and activation free energies from single-molecule pulling experiments. Phys. Rev. Lett. 96, 108101 (2006).
29. Raible, M. et al. Theoretical analysis of single-molecule force spectroscopy experiments: heterogeneity of chemical bonds. Biophys. J. 90, 3851 -3864 (2006).
30. Diezemann, G. & Janshoff, A. Dynamic force spectroscopy: Analysis of reversible bond-breaking dynamics. J. Chem. Phys. 129, 0849041 (2008).