Role of enzymatically inactive procathepsin D in lung cancer

Anticancer Research

Volumn 24, Issue 5 A, 2004, Pages 2739-2743

  Vetvicka, Vaclav ^a   Vetvickova, Jana ^a   Benes, Petr ^b  

^a University of Louisville School of Medicine   (United States)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Lung cancer; Procathepsin D

Indexed keywords

ACTIVATION PEPTIDE; AMINO ACID; CATHEPSIN; GROWTH FACTOR; MATRIGEL; PEPTIDE DERIVATIVE; PROCATHEPSIN D; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER INVASION; CELL PROLIFERATION; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN SECRETION;

BREAST NEOPLASMS; CATHEPSIN D; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; PEPTIDE FRAGMENTS;

EID: 6444243681     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Westley BR and May FEB: Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells. Nucleid Acid Res 15: 3773-3786, 1987.
2. Vetvicka V, Vetvickova J and Fusek M: Effect of procathepsin D and its activation peptide on prostate cancer cells. Cancer Lett 129: 55-59, 1998.
3. Vignon F, Capony F, Chambon M, Freiss G, Garcia M and Rochefort H: Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52K protein. Endocrinology 118: 1537-1545, 1986.
4. Rochefort H: Cathepsin D in breast cancer: A tissue marker associated with metastasis. Eur J Cancer 28A: 1780-1783, 1992.
5. Garcia D, Dercoq Q, Pujol P and Rochefort H: Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency. Oncogene 5: 1809-1814, 1990.
6. Vetvicka V, Vetvickova J and Fusek M: Effect of human procathepsin D on proliferation of human cell lines. Cancer Lett 79: 131-135, 1994.
7. Fusek M and Vetvicka V: Mitogenic function of human procathepsin D.- role of the activation peptide. Biochem J 303: 775-780, 1994.
8. Taylor DD and Gercel-Taylor C: Tumor-reactive immunoglobulins in ovarian cancer: diagnostic and therapeutic significance? Oncology Reports 5: 1519-1524, 1998.
9. Strojan P, Budihna M, Smid L, Vrhovec I and Skrk J: Cathepsin D in tissue and serum of patients with squamous cell carcinoma of the head and neck. Cancer Letters 130: 49-56, 1998.
10. Nazeer T, Church K, Amato C, Ambros RA, Rosano TG, Malfetano JH and Ross JS: Comparative quantitative immunohistochemical and immunoradiometric determinations of cathepsin D in endometrial adenocarcinoma: predictors of tumor aggressiveness. Mod Pathol 7: 469-474, 1994.
11. Huet G, Zerimech F, Dieu M-C, Hemon B, Gerard G, Balduyck M, Janin A, Lafyatis R, Degand P, Dieu MC, Janin A and Lafyatis R: The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator. Int J Cancer 57: 875-882, 1994.
12. Ferrandina G, Scambia G, Panici P, Alamdori G, Paludetti G, Cadoni G, Distefano N, Maurizi M and Mancuso S: Cathepsin D in primary squamous laryngeal tumors: correlation with clinico-pathological parameters and receptor status. Cancer Lett 67: 133-138, 1992
13. Chambon M, Rebillard X, Rochefort H, Brouillet JP, Baldet P, Guiter J and Maudelonde T: Cathepsin D cytosolic assay and immunohistochemical quantification in human prostate tumors. Prostate 24: 320-325, 1994.
14. Tedone T, Correale M, Barbadossa G, Casavola V, Paradiso A and Reshkin SJ: Release of the aspartyl protease cathepsin D is associated with and facilitates human breast cancer cell invasion. FASEB J 11: 785-792, 1997.
15. Johnson MD, Torri JA, Lippman ME and Dickson RB: The role of cathepsin D in the invasiveness of human breast cancer cells. Cancer Res 53: 873-877, 1993.
16. Vetvicka V, Benes P and Fusek M: Procathepsin D in breast cancer: What do we know? Effects of ribozymes and other inhibitors. Cancer Gene Therapy 9: 854-863, 2002.
17. Chyczewski L, Plonski A, Chyczewska E, Furman M, Ostrowska H, Niklinski J and Kozlowski M: Activity and tissue localization of cathepsin D in non small cell lung cancer. Roc Akad Medyc 42: 217-229, 1997.
18. Zhixin W and Xiaoyan Z: Expression and prognostic relation of cathepsin D in non-small lung cancer tissues and lymph nodes. Chin J Tuberc Respir Dis 21: 164-166, 1998.
19. Wozniak A, Drewa T, Rozwodowska M, Drewa G, Lambrecht W and Wisniewska I: Activity of some lysosomal enzymes in serum and in tumors of patients with squamous cell lung carcinoma. Neoplasma 49: 10-15, 2002.
20. Ledakis P, Tester WT, Rosenberg N, Romero-Fishmann D, Daskal I and Lah TT: Cathepsins D, B, and L in malignant human lung tissue. Clin Cancer Res 2: 561-568, 1996.
21. Vetvicka V, Vetvickova J and Fusek M: Anti-human procathepsin D activation peptide antibodies inhibit breast cancer development. Breast Cancer Res Treat 57: 261-269, 1999.
22. Koelsch G, Metcalf P, Vetvicka V and Fusek M: Human procathepsin D: three-dimensional model and isolation, In: Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications (Takahashi K ed.). New York, Plenum Press. 1995, pp. 273-278.
23. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277: 680-585, 1970.
24. Vetvicka V, Vetvickova J, Hilgert I, Voburka Z and Fusek M: Analysis of the interaction of procathepsin D activation peptide with breast cancer cells. Int J Cancer 73: 403-409, 1997.
25. Rochefort H and Capony F: Alterations of cathepsin D in human breast cancer. In: Proteolysis and Protein Turnover (Bond JS Barren AJ, eds). London, Portland Press. 1993, pp. 233-238.
26. Glondu M, Coopman P, Laurent-Matha V, Garcia M, Rochefort H and Liaudet-Coopman E: A mutated cathepsin D devoid of its catalytic activity stimulates the growth of cancer cells. Oncogene 20: 6920-6929, 2001.
27. Vetvicka V, Vetvickova J and Fusek M: Role of procathepsin D activation peptide in prostate cancer growth. Prostate 44: 1-7, 2001.
28. Dahms NM, Lobel P and Kornfeld S: Mannose-6-phosphate receptorts and lysosomal enzyme targeting. J Biol Chem 264: 12115-12118, 1989.