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Volumn 24, Issue 5 A, 2004, Pages 2595-2599

Loss of heterozygosity and nonsense mutation in Apc in azoxymethane-induced colonic tumours in Min mice

Author keywords

catenin; Adenomatous polyposis coli; Azoxymethane; LOH; Min mice

Indexed keywords

BETA CATENIN;

EID: 6444237027     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (29)
  • 1
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pilot HC and Dove WF: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247: 322-324, 1990.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pilot, H.C.2    Dove, W.F.3
  • 3
    • 0028987249 scopus 로고
    • Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • Munemitsu S, Albert I, Souza B, Rubinfeld B and Polakis P: Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 92: 3046-3050, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 4
    • 0036174452 scopus 로고    scopus 로고
    • Beta-catenin - A linchpin in colorectal carcinogenesis?
    • Wong NA and Pignatelli M: Beta-catenin-a linchpin in colorectal carcinogenesis? Am J Pathol 160: 389-401, 2002.
    • (2002) Am J Pathol , vol.160 , pp. 389-401
    • Wong, N.A.1    Pignatelli, M.2
  • 6
    • 0347683364 scopus 로고    scopus 로고
    • Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice
    • Møllersen L, Vikse R, Andreassen Å, Steffensen I-L, Mikalsen A, Paulsen JE and Alexander J: Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice. Mutat Res 557: 29-40, 2004.
    • (2004) Mutat Res , vol.557 , pp. 29-40
    • Møllersen, L.1    Vikse, R.2    Andreassen, Å.3    Steffensen, I.-L.4    Mikalsen, A.5    Paulsen, J.E.6    Alexander, J.7
  • 7
    • 0037233679 scopus 로고    scopus 로고
    • Age-dependent susceptibility to azoxymethane-induced and spontaneous tumorigenesis in the Min/+ mouse
    • Paulsen JE, Steffensen I-L, Namork E, Eide TJ and Alexander J: Age-dependent susceptibility to azoxymethane-induced and spontaneous tumorigenesis in the Min/+ mouse. Anticancer Res 23: 259-265, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 259-265
    • Paulsen, J.E.1    Steffensen, I.-L.2    Namork, E.3    Eide, T.J.4    Alexander, J.5
  • 8
    • 0037044114 scopus 로고    scopus 로고
    • Enhanced colon carcinogenesis induced by azoxymethane in Min mice occurs via a mechanism independent of beta-catenin mutation
    • Suzui M, Okuno M, Tanaka T, Nakagama H and Moriwaki H: Enhanced colon carcinogenesis induced by azoxymethane in Min mice occurs via a mechanism independent of beta-catenin mutation. Cancer Lett 183: 31-41, 2002.
    • (2002) Cancer Lett , vol.183 , pp. 31-41
    • Suzui, M.1    Okuno, M.2    Tanaka, T.3    Nakagama, H.4    Moriwaki, H.5
  • 9
    • 0021287405 scopus 로고
    • Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents
    • Pegg AE: Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. Cancer Invest 2: 223-231, 1984.
    • (1984) Cancer Invest , vol.2 , pp. 223-231
    • Pegg, A.E.1
  • 10
    • 0036856459 scopus 로고    scopus 로고
    • Mechanisms of carcinogenicity/chemotherapy by O6-methylguanine
    • Margison GP, Santibanez Koref MF and Povey AC: Mechanisms of carcinogenicity/chemotherapy by O6-methylguanine. Mutagenesis 17: 483-487, 2002.
    • (2002) Mutagenesis , vol.17 , pp. 483-487
    • Margison, G.P.1    Santibanez Koref, M.F.2    Povey, A.C.3
  • 11
    • 0034807002 scopus 로고    scopus 로고
    • High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase
    • Ochiai M, Ubagai T, Kawamori T, Imai H, Sugimura T and Nakagama H: High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase. Carcinogenesis 22: 1551-1555, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 1551-1555
    • Ochiai, M.1    Ubagai, T.2    Kawamori, T.3    Imai, H.4    Sugimura, T.5    Nakagama, H.6
  • 12
    • 0031984227 scopus 로고    scopus 로고
    • Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
    • Takahashi M, Fukuda K, Sugimura T and Wakabayashi K: Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res 58: 42-46, 1998.
    • (1998) Cancer Res , vol.58 , pp. 42-46
    • Takahashi, M.1    Fukuda, K.2    Sugimura, T.3    Wakabayashi, K.4
  • 13
    • 0034122380 scopus 로고    scopus 로고
    • Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane
    • Takahashi M, Nakatsugi S, Sugimura T and Wakabayashi K: Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane. Carcinogenesis 21: 1117-1120, 2000.
    • (2000) Carcinogenesis , vol.21 , pp. 1117-1120
    • Takahashi, M.1    Nakatsugi, S.2    Sugimura, T.3    Wakabayashi, K.4
  • 15
    • 0035392983 scopus 로고    scopus 로고
    • Qualitative and quantitative relationship between dysplastic aberrant crypt foci and tumorigenesis in the Min/+ mouse Colon
    • Paulsen JE, Steffensen I-L, Løberg EM, Husøy T, Namork E and Alexander J: qualitative and quantitative relationship between dysplastic aberrant crypt foci and tumorigenesis in the Min/+ mouse Colon. Cancer Res 61: 5010-5015, 2001.
    • (2001) Cancer Res , vol.61 , pp. 5010-5015
    • Paulsen, J.E.1    Steffensen, I.-L.2    Løberg, E.M.3    Husøy, T.4    Namork, E.5    Alexander, J.6
  • 17
    • 0031417627 scopus 로고    scopus 로고
    • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice
    • Steffensen I-L, Paulsen JE, Eide TJ and Alexander J: 2-Amino-1-methyl-6- phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice. Carcinogenesis 18: 1049-1054, 1997.
    • (1997) Carcinogenesis , vol.18 , pp. 1049-1054
    • Steffensen, I.-L.1    Paulsen, J.E.2    Eide, T.J.3    Alexander, J.4
  • 18
    • 0034926965 scopus 로고    scopus 로고
    • Intestinal tumours induced by the food carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-o]pyridine in multiple intestinal neoplasia mice have truncation mutations as well as loss of the wild-type Apc+ allele
    • Andreassen Å, Vikse R, Steffensen I-L, Paulsen JE and Alexander J: Intestinal tumours induced by the food carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-o]pyridine in multiple intestinal neoplasia mice have truncation mutations as well as loss of the wild-type Apc+ allele. Mutagenesis 16: 309-315, 2001.
    • (2001) Mutagenesis , vol.16 , pp. 309-315
    • Andreassen, Å.1    Vikse, R.2    Steffensen, I.-L.3    Paulsen, J.E.4    Alexander, J.5
  • 20
    • 0030902858 scopus 로고    scopus 로고
    • Somatic mutational mechanisms involved in intestinal tumor formation in Min mice
    • Shoemaker AR, Luongo C, Moser AR, Marton LJ and Dove WF: Somatic mutational mechanisms involved in intestinal tumor formation in Min mice. Cancer Res 57: 1999-2006, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1999-2006
    • Shoemaker, A.R.1    Luongo, C.2    Moser, A.R.3    Marton, L.J.4    Dove, W.F.5
  • 21
    • 0037182161 scopus 로고    scopus 로고
    • One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo [4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Ape gene
    • Andreassen Å, Møllersen L, Vikse R, Steffensen I-L, Mikalsen A, Paulsen JE and Alexander J: One dose of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) or 2-amino-3-methylimidazo [4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Ape gene. Mutat Res 517: 157-166, 2002.
    • (2002) Mutat Res , vol.517 , pp. 157-166
    • Andreassen, Å.1    Møllersen, L.2    Vikse, R.3    Steffensen, I.-L.4    Mikalsen, A.5    Paulsen, J.E.6    Alexander, J.7
  • 22
    • 0026608232 scopus 로고
    • PCR amplification of specific alleles
    • Sommer SS: PCR amplification of specific alleles. Science 255: 514, 1992.
    • (1992) Science , vol.255 , pp. 514
    • Sommer, S.S.1
  • 25
    • 0033028730 scopus 로고    scopus 로고
    • Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc
    • Bjerknes M and Cheng H: Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc. Am J Pathol 154: 1831-1834, 1999.
    • (1999) Am J Pathol , vol.154 , pp. 1831-1834
    • Bjerknes, M.1    Cheng, H.2
  • 26
    • 0031748026 scopus 로고    scopus 로고
    • Mutations of the Ape gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats
    • De Filippo C, Caderni G, Bazzicalupo M, Briani C, Giannini A, Fazi M and Dolara P: Mutations of the Ape gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats. Br J Cancer 77: 2148-2151, 1998.
    • (1998) Br J Cancer , vol.77 , pp. 2148-2151
    • De Filippo, C.1    Caderni, G.2    Bazzicalupo, M.3    Briani, C.4    Giannini, A.5    Fazi, M.6    Dolara, P.7
  • 27
    • 0026469750 scopus 로고
    • Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine with 2′-deoxyguanosine and its phosphate esters
    • Nagaoka H, Wakabayashi K, Kim SB, Kim IS, Tanaka Y, Ochiai M, Tada A, Nukaya H, Sugimura T and Nagao M: Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine with 2′-deoxyguanosine and its phosphate esters. Jpn J Cancer Res 83: 1025-1029, 1992.
    • (1992) Jpn J Cancer Res , vol.83 , pp. 1025-1029
    • Nagaoka, H.1    Wakabayashi, K.2    Kim, S.B.3    Kim, I.S.4    Tanaka, Y.5    Ochiai, M.6    Tada, A.7    Nukaya, H.8    Sugimura, T.9    Nagao, M.10
  • 28
    • 0037173075 scopus 로고    scopus 로고
    • Intestinal adenomas can develop with a stable karyotype and stable microsatellites
    • Haigis KM, Caya JG, Reichelderfer M and Dove WF: Intestinal adenomas can develop with a stable karyotype and stable microsatellites. Proc Natl Acad Sci USA 99: 8927-8931, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8927-8931
    • Haigis, K.M.1    Caya, J.G.2    Reichelderfer, M.3    Dove, W.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.