Hantavirus pulmonary syndrome in Latin America

Current Opinion in Infectious Diseases

Volumn 17, Issue 5, 2004, Pages 427-431

  Pini, Noemi ^a,b  

^a Natl Inst of Human Viral Diseases   (Argentina)

^b Instituto Nacional de Enfermedades Virales Humanas Dr Julio I Maiztegui   (Argentina)

Author keywords

Hantavirus pulmonary syndrome; Latin America

Indexed keywords

ANTIBODY DETECTION; ARGENTINA; BLEEDING; BRAZIL; CHILE; DISEASE SEVERITY; ETHNIC DIFFERENCE; GEOGRAPHIC DISTRIBUTION; HANTAVIRUS; HANTAVIRUS PULMONARY SYNDROME; HUMAN; PANAMA; PARAGUAY; PROGNOSIS; REVIEW; RURAL AREA; SOUTH AND CENTRAL AMERICA; UNITED STATES; URUGUAY; VIRUS IDENTIFICATION;

ANIMALS; DISEASE RESERVOIRS; HANTAVIRUS; HANTAVIRUS PULMONARY SYNDROME; HUMANS; LATIN AMERICA; MURIDAE; RODENT DISEASES;

EID: 6444226651     PISSN: 09517375     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001432-200410000-00007     Document Type: Review

References (39)

1. Nichol S, Spiropoulou C, Morzunov S, et al. Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science 1993; 262:914-917.
2. Ksiazek TG, Peters CJ, Rollin PE, et al. Identification of a new North American hantavirus that causes acute pulmonary insufficiency. Am J Trop Med Hyg 1995; 52:117-123.
3. Hjelle B, Anderson B, Torrez-Martinez N, et al. Prevalence and geographic genetic variation of hantaviruses of New World harvest mice (Reithrodontomys): identification of a divergent genotype from a Costa Rican Reithrodontomys mexicanus. Virology 1995; 207:452-459.
4. Lopez N, Padula P, Rossi C, et al. Genetic identification of a new hantavirus causing severe pulmonary syndrome in Argentina. Virology 1996; 220:223-226.
5. Da Silva MV, Vasconcelos MJ, Hidalgo NTR, et al. Hantavirus pulmonary syndrome, report of the first three cases in São Paulo, Brazil. Rev Inst Med Trop S Paulo 1997; 39:231-234.
6. Johnson AM, Bowen MD, Ksiazek TG, et al. Laguna Negra virus associated with HPS in western Paraguay and Bolivia. Virology 1997; 238:115-127.
7. Bharadwaj M, Botten J, Torrez-Martinez N, Hjelle B. Rio Mamore virus: genetic characterisation of a newly recognised hantavirus of the pygmy rice rat, Oligoryzomys microtis, from Bolivia. Am J Trop Med Hyg 1997; 57:368-374.
8. Fulhorst CF, Monroe MC, Salas RA, et al. Isolation, characterisation, and geographic distribution of Caño Delgadito virus, a newly discovered South American hantavirus (family Bunyaviridae). Virus Res 1997; 51:159-171.
9. Levis SC, Rowe JE, Morzunov S, et al. New hantaviruses causing hantavirus pulmonary syndrome in central Argentina. Lancet 1997; 349:998-999.
10. Johnson AM, De Souza LTM, Ferreira IB, et al. Genetic investigation of novel hantaviruses causing fatal HPS in Brazil. J Med Virol 1999; 59:527-535.
11. Levis S, Morzunov S, Rowe J, et al. Genetic diversity and epidemiology of hantaviruses in Argentina. J Infect Dis 1998; 177:529-538.
12. Vincent MJ, Quiroz E, Gracia F, et al. Hantavirus pulmonary syndrome in Panama: identification of novel hantaviruses and their likely reservoirs. Virology 2000; 277:14-19.
13. Peters CJ. Hantavirus pulmonary syndrome in the Americas. In: Sheld W, Craig WA, Hughes M, editors. Emerging Infections 2. ASM Press: Washington, DC; 1998. pp 17-64.
14. Tischler ND, Fernandez J, Muller I, et al. Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis. Biol Res 2003; 36:201-210. Interesting paper with a complete analysis of molecular properties of the three RNA segments of the first human ANDV isolate. Protein structure differences could be responsible for differences in pathogenicity, according to authors.
15. Rivas YJ, Moros Z, Moron D, et al. The seroprevalences of anti-hantavirus IgG antibodies among selected Venezuelan populations. Ann Trop Med Parasitol 2003; 97:61-67. This paper reports a low but widespread seroprevalence to hantavirus in Venezuela, where Caño Delgadito virus was previously identified in Sigmodon alstoni.
16. Campos GM, Moro de Sousa RL, Badra SJ, et al. Serological survey of hantavirus in Jardinopolis County, Brazil. J Med Virol 2003; 71:417-422. Serologic survey with a high seroprevalence of antibodies against hantavirus and different epidemiologic findings compared with previous studies. More than one hantavirus with less virulence is proposed.
17. Ferrer JF, Galligan D, Esteban E, et al. Hantavirus infection in people inhabiting a highly endemic region of the Gran Chaco territory, Paraguay: association with Trypanosoma cruzi infection, epidemiological features and haematological characteristics. Ann Trop Med Parasitol 2003; 97:269-280. Extension of a previous study, the exceptionally high prevalence of antibodies to hantavirus in western Paraguay is confirmed and several risk factors are analyzed.
18. Chu YK, Owen RD, Gonzalez LM, Jonsson CB. The complex ecology of hantavirus in Paraguay. Am J Trop Med Hyg 2003; 69:263-268. A very interesting paper reporting antibodies to hantaviruses in ten species of sigmodontine rodents in Paraguay and in an Indian community living in an area without previous HPS confirmed cases. Authors have recovered viral RNA in five of the seropositive rodents from four different species, which could correspond to new hantavirus(es) circulating in the country.
19. Pini N, Levis S, Calderon G, et al. Hantavirus infection in humans and rodents, northwestern Argentina. Emerg Infect Dis 2003; 9:1070-1076. This paper analyzes a complex and intriguing area where a noticeable low fatality rate was seen. High seroprevalence in human population, risk factors associated with infection and new rodent species with antibodies to hantavirus are reported.
20. Castillo C, Villagra E, Sanhueza L, et al. Prevalence of antibodies to hantavirus among family and health care worker contacts of persons with hantavirus cardiopulmonary syndrome: lack of evidence for nosocomial transmission of Andes virus to health care workers in Chile. Am J Trop Med Hyg 2004; 70:302-304. Survey of contacts of HPS cases showed a low seroprevalence in family member contacts and no evidence of nosocomial transmission of ANDV.
21. Ferres M, Vial P. Hantavirus infection in children. Curr Opin Pediatr 2004; 16:70-75. A complete review of pathogenesis, clinical and epidemiologic aspects of hantaviruses disease, with special respect to SNV and ANDV infection in children. The lower incidence of pediatric cases in North America is proposed to be caused by a lower exposure, a lesser genetic resistance of the host, or both factors; a more simple hypothesis suggests the presence of less virulent strains.
22. Enria D, Padula P, Segura EL, et al. Hantavirus pulmonary syndrome in Argentina: possibility of person to person transmission. Medicina (B Aires) 1997; 58:709-711.
23. Wells RM, Sosa Stani S, Yadón Z, et al. An unusual hantavirus outbreak in southern Argentina: person-to-person transmission? Emerg Infect Dis 1997; 3:171-174.
24. Pinna DM, Martinez VP, Bellomo CM, et al. New epidemiologic and molecular evidence of person to person transmission of hantavirus Andes Sout [in Spanish]. Medicina (B Aires) 2004; 64:43-46. Report of an outbreak of three cases that adds evidence supporting person-to-person transmission of ANDV.
25. Lazaro ME, Resa AJ, Barclay CM, et al. Hantavirus pulmonary syndrome in southern Argentina [in Spanish]. Medicina (B Aires) 2000; 60:289-301.
26. Riquelme R, Riquelme M, Torres A, et al. Hantavirus pulmonary syndrome, southern Chile. Emerg Infect Dis 2003; 9:1438-1443. This excellent paper performed an exhaustive analysis of the epidemiological, clinical, radiographic, treatment and laboratory aspects of 25 cases in southern Chile. The main clinical differences found in classical HPS include a higher percentage of hemorrhages and of alterations in renal function. The identification of three groups of patients according to a clinical score had a prognostic value.
27. Figueiredo LT, Moreli ML, Campos GM, Sousa RL. Hantaviruses in Sao Paulo State, Brazil. Emerg Infect Dis 2003; 9:891-892. Brief analysis of HPS cases in Ribeirão Preto due to Araraquara virus and suggestion of another circulating hantavirus that causes subclinical forms.
28. Pini N, Resa A, Laime G, et al. Hantavirus infection in children in Argentina. Emerg Infect Dis 1998; 4:85-87.
29. Soza G, Lorca P, Puebla S, et al. Hantavirus cardiopulmonary syndrome in pediatric population [in Spanish]. Rev Chil Infect 2000; 17:248-257.
30. Calderon G, Pini N, Bolpe J, et al. Hantavirus reservoir host associated with peridomestic habitats in Argentina. Emerg Infect Dis 1999; 5:792-797.
31. Suarez OV, Cueto GR, Cavia R, et al. Prevalence of infection with hantavirus in rodent populations of central Argentina. Mem Inst Oswaldo Cruz 2003; 98:727-732.
32. Seijo A, Pini N, Levis S, et al. Study of hantavirus Seoul in a human and rodent population from a marginal area in Buenos Aires City. Medicina (B Aires) 2003; 63:193-196. Serologic survey in Rattus norvegicus by ELISA with SNV and Seoul virus antigens showed evidence of the circulation of the late virus among rodents with no evidence of infection in human samples.
33. LeDuc J, Smith GA, Childs JE, et al. Global survey of antibody to Hantaan-related viruses among peridomestic rodents. Bull WHO 1986; 64:139-144.
34. Delfraro A, Clara M, Tome L, et al. Yellow pigmy rice rat (Oligoryzomys flavescens) and hantavirus pulmonary syndrome in Uruguay. Emerg Infect Dis 2003; 9:846-852. Interesting paper that reports the first study to determine rodent reservoirs to hantaviruses in Uruguay. From the species trapped in likely sites of exposure of HPS cases, only O. flavescens showed antibodies to hantavirus, and Andes Central Plata genotype was recovered from rodent tissues.
35. Padula PJ, Colavecchia SB, Martinez VP, et al. Genetic diversity, distribution, and serological features of hantavirus infection in five countries in South America. J Clin Microbiol 2000; 38:3029-3035.
36. Salazar-Bravo J, Armien B, Suzan G, et al. Serosurvey of wild rodents for hantaviruses in Panama, 2000-2002. J Wildl Dis 2004; 40:103-109. The serologic study of small mammals in Panama showed different rodent species, adding to the previously recognized reservoirs of hantaviruses.
37. Torres-Perez F, Navarrete-Droguett J, Aldunate R, et al. Peridomestic small mammals associated with confirmed cases of human hantavirus disease in southcentral Chile. Am J Trop Med Hyg 2004; 70:305-309. A confirmation of peridomestic and rural risk by detecting antibodies in rodents trapped in association with the occurrence of HPS cases.
38. Custer DM, Thompson E, Schmaljohn CS, et al. Active and passive vaccination against hantavirus pulmonary syndrome with Andes virus M genome segment-based DNA vaccine. J Virol 2003; 77:9894-9905. Excellent approach to the development of a product that could confer passive protection even after exposure to ANDV and possibly to other hantaviruses causing HPS. The gene-based HPS vaccine was tried in rhesus macaques and the protective answer of the monkey serum was studied in the ANDV-hamster lethal-disease model.
39. Hooper JW, Larsen T, Custer D, Schmaljohn CS. A lethal disease model for hantavirus pulmonary syndrome. Virology 2001; 255:269-278.