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Volumn 126, Issue 42, 2004, Pages 13592-13593

Synthetic multifunctional pores with external and internal active sites for ligand gating and noncompetitive blockage

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN DERIVATIVE;

EID: 6444223733     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045987+     Document Type: Article
Times cited : (55)

References (17)
  • 9
    • 6444226426 scopus 로고    scopus 로고
    • note
    • The terms "ligand gating" and "blockage" together with "open(ing)" and "close/closing" are used to refer explicitly to function without any structural implications (i.e., increase and decrease in "pore activity" in response to ligands and blockers, respectively). We emphasize that the structural basis of "ligand gating" in this study (i.e., ligand-mediated changes in pore-membrane interactions) is designed to differ from many cases of biological "ligand gating" (i.e., ligand-mediated changes in pore/ channel conformation).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.