High blood pressure in acute ischaemic stroke - Broadening therapeutic horizons

Cerebrovascular Diseases

Volumn 27, Issue SUPPL. 1, 2009, Pages 156-161

  Sare, Gillian M ^a   Geeganage, Chamila ^a   Bath, Philip M W ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Acute ischaemic stroke; Antihypertensive agents; Blood pressure

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CANDESARTAN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; GLYCERYL TRINITRATE; INSULIN; LABETALOL; LISINOPRIL; LOSARTAN; MAGNESIUM; NIMODIPINE; PERINDOPRIL; PLACEBO; POTASSIUM; PROPRANOLOL; TELMISARTAN; THIAZIDE DIURETIC AGENT;

BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; CLINICAL PRACTICE; CLINICAL TRIAL; CONFERENCE PAPER; DEATH; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG MEGADOSE; HEMATOMA; HUMAN; HYPERGLYCEMIA; HYPERTENSION; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; HUMANS; HYPERTENSION; PRACTICE GUIDELINES AS TOPIC; RISK ASSESSMENT; STROKE; TREATMENT OUTCOME;

EID: 64349117776     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000200454     Document Type: Conference Paper

References (53)

1. Wallace JD, Levy LL: Blood pressure after stroke. JAMA 1981;246:2177-2180.
2. Leonardi-Bee J, Bath PMW, Phillips SJ, Sandercock PAG, for the IST Collaborative Group: Blood pressure and clinical outcomes in the International Stroke Trial. Stroke 2002;33:1315-1320.
3. Carlberg B, Asplund K, Hagg E: Factors influencing admission blood pressure levels in patients with acute stroke. Stroke 1991;4: 527-530.
4. Britton M, Carlsson A, de Faire U: Blood pressure course in patients with acute stroke and matched controls. Stroke 1986;17:861-864.
5. Willmot M, Leonardi-Bee J, Bath PM: High blood pressure in acute stroke and subsequent outcome: a systematic review. Hypertension 2004;43:18-24.
6. Sprigg N, Gray LJ, Bath PMW, Boysen G, De Deyn PP, Friis P, Leys D, Marttila R, Olsson J-E, O'Neill D, Ringlestein B, van der Sande J-J, Lindenstrom E, TAIST Investigators: Relationship between outcome and baseline blood pressure and other haemodynamic measures in acute ischaemic stroke: data f rom the TAIST trial. J Hy pertens 2006;24: 1413-1417.
7. Bowes MP, Zivin JA, Thomas GR, Thibodeaux H, Fagan SC: Acute hypertension, but not thrombolysis, increases the incidence and severity of hemorrhagic transformation following experimental stroke in rabbits. Exp Neurol 1996;141:40-46.
8. Saku Y, Choki J, Waki R, Masuda J, Tamaki K, Fujishima M, Ogata J: Hemorrhagic in-farct induced by arterial hypertension in cat brain following middle cerebral artery occlusion. Stroke 1990;21:589-595.
9. Sare GM, Gray LJ, England T, Geeganage CM, Bath PMW: The relationship between baseline blood pressure and CT findings in acute stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (abstract). Stroke 2008;39:610.
10. Meyer JS, Shimazu K, Fukuuchi Y, Ohuchi T, Okamoto S, Koto A, Ericsson AD: Impaired neurogenic cerebrovascular control and dysautoregulation after stroke. Stroke 1973;4: 169-186.
11. Hachinski V: Hypertension in acute ischaemic strokes. Arch Neurol 1985;42:1002.
12. Sare GM, Gray LJ, Bath PMW: Effect of antihypertensive agents on cerebral blood flow and cerebral blood flow velocity in acute ischaemic stroke - systematic review of controlled studies. J Hypertens 2008; 26:1058-1064.
13. Hakim AM, Evans AC, Berger L, Kuwabara H, Worsley K, Marchal G, Biel C, Pokrupa R, Diksic M, Meyer E, et al: The effect of ni-modipine on the evolution of human cerebral infarction studied by PET. J Cereb Blood Flow Metab 1989; 9:523-534.
14. Lisk D, Grotta J, Lamki L, et al: Should hypertension be treated after acute stroke? A randomised controlled trial using single photon emission computed tomography. Arch Neurol 1993;50:855-862.
15. Dyker AG, Grosset DG, Lees K: Perindopril reduces blood pressure but not cerebral blood flow in patients with recent cerebral ischemic stroke. Stroke 1997;28:580-583.
16. Infield B, Davis SM, Donnan GA, Yasaka M, Lichtenstein M, Mitchell PJ, Fitt GJ: Nimodipine and perfusion changes after stroke. Stroke 1999;30:1417-1423.
17. Nazir FS, Overell JR, Bolster A, Hilditch TE, Reid JL, Lees KR: The effect of losartan on global and focal cerebral perfusion and on renal function in hypertensives in mild early ischaemic stroke. J Hypertens 2004;22:989-995.
18. Nazir FS, Overell JR, Bolster A, Hilditch TE, Lees KR: Effect of perindopril on cerebral and renal perfusion on normotensives in mild early ischaemic stroke: a randomized controlled trial. Cerebrovasc Dis 2005; 19: 77-83.
19. Willmot M, Ghadami A, Whysall B, Clarke W, Wardlaw J, Bath PM: Transdermal glyceryl trinitrate lowers blood pressure and maintains cerebral blood flow in recent stroke. Hypertension 2006;47:1209-1215.
20. Eveson DJ, Robinson TG, Potter JF: Lisinopril for the treatment of hypertension within the first 24 hours of acute ischemic stroke and follow-up. Am J Hypertens 2007;20: 270-277.
21. Potter J, for the CHHIPS Trialists: Control of hypertension and hypotension immediately post-stroke (CHHIPS) pilot study; in Am Stroke Assoc Int Stroke Conf, February 2008, New Orleans.
22. Nazir FS, Overell JR, Hilditch TE, Lees KR: The effect of losartan on global and focal cerebral perfusion and renal function in hypertensives in early ischaemic stroke (abstract). Cerebrovasc Dis 2003; 16(suppl 4):31.
23. Schrader J, Luders S, Kulchewski A, Berger J, Zidek W, Treib J, Einhaupl K, Diener H-C, Dominiak P: The ACCESS Study. Evaluation of acute candesartan therapy in stroke survivors. Stroke 2003;34:1699-1703.
24. Diener H-C, Sacco RL, Yusuf S; for the Steering Committee and PRoFESS Study Group: Rationale, design and baseline data of a randomized, double-blind, controlled trial comparing two antithrombotic regimens (a fixed-dose combination of extended-release dipyridamole plus ASA with clopidogrel) and telmisartan versus placebo in patients with strokes: the prevention regimen for effectively avoiding second strokes trial (PRoFESS). Cerebrovasc Dis 2007;23:368-380.
25. Barer DH, Cruickshank JM, Ebrahim SB, Mitchell JR: Low dose beta blockade in acute stroke ('BEST' trial): an evaluation. BMJ 1988;296:737-741.
26. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group: Tissue plasminogen activator for acute stroke. N Engl J Med 1995;333:1581-1587.
27. Brott T, Lu M, Kothari R, Fagan SC, Frankel M, Grotta JC, Broderick J, Kwiatkowski T, Lewandowski C, Haley E, Marler J, Tilley B, The NINDS rt-PA Stroke Study Group: Hypertension and its treatment in the NINDS rt-PA stroke trial. Stroke 1998; 29: 1504-1509.
28. Horn J, Limburg M: Calcium antagonists for acute ischaemic stroke. Cochrane Database Syst Rev 2000;CD001928.
29. Blood pressure in Acute Stroke Collaboration: The effect of vasoactive drugs on blood pressure and outcome in acute stroke. Cochrane Database Syst Rev 2001; CD000039.
30. Wahlgren NG, MacMahon DG, de Keyser J, Indredavik B, Ryman T, INWEST Study Group: Intravenous Nimodipine West European Stroke Trial (INWEST) of nimodipine in the treatment of acute ischaemic stroke. Cerebrovasc Dis 1994;4:204-210.
31. Ahmed N, Nasman P, Wahlgren NG: Effect of intravenous nimodipine on blood pressure and outcome after acute stroke. Stroke 2000;31:1250-1255.
32. Bridgers SL, Koch G, Munera C, Karwon M, Kurtz NM: Intravenous nimodipine in acute stroke: interim analysis of randomized trials (abstract). Stroke 1991;22:153.
33. Eames PJ, Robinson TG, Panerai RB, Potter JF: Bendrofluazide fails to reduce elevated blood pressure levels in the immediate post stroke period. Cerebrovasc Dis 2005; 19:253-259.
34. Eames JP, Robinson TG, Panerai RB, Potter J: The systemic haemodynamic and cerebral autoregulatory effects of bendrofluazide in the subacute post-stroke period. J Hypertens 2004;22:2017-2024.
35. Bath PMW, Pathansali R, Iddenden R, Bath FJ: The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure and platelet function in acute stroke. Cerebrovasc Dis 2001;11:265-272.
36. Rashid P, Weaver C, Leonardi-Bee JA, Fletcher S, Bath FJ, Bath PMW: The effects of trans-dermal glyceryl trinitrate, a nitric oxide donor on blood pressure, cerebral and cardiac haemodynamics and plasma nitric oxide levels in acute stroke. J Stroke Cerebrovasc Dis 2003;13:143-151.
37. Intravenous Magnesium Efficacy in Stroke (IMAGES) Study Investigators: Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial. Lancet 2004;363:439.
38. Scott JF, Robinson GM, French JM, O'Connell JE, Alberti KG, Gray CS: Blood pressure response to glucose potassium insulin therapy in patients with acute stroke with mild to moderate hyperglycaemia. J Neurol Neurosurg Psychiatry 2001;70:401-404.
39. Gray CS, Hildreth AJ, Sandercock PA, O'Connell JE, Johnston DE, Cartlidge NE, Bamford JM, James OF, Alberti KG, Gist Trialists Collaboration: Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK). Lancet Neurol 2007;6:397-406.
40. Geeganage C, Sare GM, Bath PM: Pulse pressure as a predictor of stroke. Expert Rev Neurother 2008;8:165-167.
41. Eveson DJ, Robinson TG, Potter JF: Lisinopril for the treatment of hypertension within the first 24 hours of acute ischemic stroke and follow-up. Am J Hypertens 2007;20: 270-277.
42. Willmot M, Ghadami A, Gray LJ, Bath PMW: The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on systemic haemodynamics and cerebral perfusion in acute stroke. J Hum Hypertens 2006;19:824-847.
43. Gray LJ, Sprigg N, Rashid PA, Willmot M, Bath PMW: Effect of nitric oxide donors on blood pressure and pulse pressure in acute and sub-actue stroke. J Stroke Cerebrovasc Dis 2006;15:245-249.
44. Nyrop M, Zweifler AJ: Platelet aggregation in hypertension and the effects of antihypertensive treatment. J Hypertens 1988;6:263-266.
45. Butterworth RJ, Cluckie A, Jackson SHD, Buxton-Thomas M, Bath PMW: Pathophysiological assessment of nitric oxide (given as sodium nitroprusside) in acute ischaemic stroke. Cerebrovasc Dis 1998;8:158-165.
46. Horn J, deHaan R, Vermeulen M, Luiten PGM, Limburg M: Nimodipine in animal model experiments of focal cerebral ischemia. Stroke 2001;32:2433-2438.
47. Willmot M, Murphy S, Leonardi-Bee J, Bath P: Systematic review of nitric oxide donors and L -arginine in experimenta l stroke: effects on infarct size and cerebral blood flow (abstract). Cerebrovasc Dis 2003; 16: S366.
48. Lu Q, Zhu YZ, Wong PT: Angiotensin receptor gene expression in candesartan mediated neuroprotection. Neuroreport 2004;15: 2643-2646.
49. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng P, Heeley E, Skulina C, Parsons MW, Kim JS, Tao QL, Li YC, Jiang DJ, Tai LW, Zhang JL, Xu E, Cheng Y, Heritier S, Morgenstern LB, Chalmers J, for the INTERACT Investigators: Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol 2008;7:391-399.
50. The European Stroke Association (ESO) Executive Committee and the ESO Writing Committee: Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. Cerebrovasc Dis 2008;25:457-507.
51. The ENOS Trial Investigators: Glyceryl trinitrate vs. control, and continuing vs. stopping temporarily prior antihypertensive therapy, in acute stroke: rationale and design of the Efficacy of Nitric Oxide in Stroke (ENOS) trial (ISRCTN99414122). Int J Stroke 2006;1:245-249.
52. COSSACS Trial Group: COSSACS (Continue or Stop post-Stroke Antihypertensives Collaborative Study): rationale and design. J Hypertens 2005;23:455-458.
53. Rashid P, Leonardi-Bee J, Bath P: Blood pressure reduction and the secondary prevention of stroke and other vascular events: a systematic review. Stroke 2003;34:2741-2749.