In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress

International Journal of Biological Sciences

Volumn 5, Issue 3, 2009, Pages 249-255

  Hassan, Hanaa A ^a   El Agmy, Sherif M ^a   Gaur, Rajiv L ^b   Fernando, Augusta ^b   Raj, Madhwa H G ^b   Ouhtit, Allal ^b  

^a Mansoura University   (Egypt)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alanine aminotransfrase; Alkaline phoasphatase; Aspartate aminotransfrease; Food additives; Garlic oil; Glycogen; Liver; Oxidative stress; Sodium nitrite

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; CREATININE; GARLIC OIL; GLUCOSE; GLUTATHIONE; SODIUM NITRITE; UREA; ALLYL COMPOUND; ALLYL SULFIDE; ANTINEOPLASTIC AGENT; CARCINOGEN; EDIBLE OIL; NITRATE; SODIUM NITRATE; SULFIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLYCOGEN ANALYSIS; IN VIVO STUDY; LIPID PEROXIDATION; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; UREA BLOOD LEVEL; ANIMAL; BLOOD; DRUG EFFECT; GLYCOGEN LIVER LEVEL; KIDNEY; LIVER; METABOLISM;

ALLIUM SATIVUM; RATTUS;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ALLYL COMPOUNDS; ANIMALS; ANTICARCINOGENIC AGENTS; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; BLOOD GLUCOSE; CARCINOGENS; CATALASE; CREATININE; DIETARY FATS, UNSATURATED; GLUTATHIONE; KIDNEY; LIPID PEROXIDATION; LIVER; LIVER GLYCOGEN; MALE; NITRATES; OXIDATIVE STRESS; RATS; SULFIDES; UREA;

EID: 64349112959     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.5.249     Document Type: Article

References (51)

1. National Toxicology Program. NTP toxicology and carcinogenesis studies of sodium nitrite (CAS No. 7632-00-0) drinking water studies in F344/N rats and B6C3F1 mice. Natl Toxicol Program Tech Rep Ser 2001; 495: 1-274.
2. Kilgore WW and Li MY. Food Additives and Contaminations. In: Doull J, Khassen CD, Amdur MD, eds. Cassarett and Doulls, Toxicology: The Basic Science of Poisons, 2nd ed. New York: Macmillian, 1980:593-607.
3. Sleight SD, Sinha DP and Uzoukwu M. Effect of sodium nitrate on reproductive performance of pregnant sows. J Am Vet Med Assoc 1972; 161:819-823.
4. Swann PF. The toxicology of nitrate, nitrite and N-nitroso compounds. J Sci Food Agrec 1975; 26:1761-1770.
5. Blanquat DG, Fritsch F and Cazotles C. Effect of dietary nitrate and nitrite on experimentally induced inflammation in the rat. Intern. J Tiss React 1983; 27:173-180.
6. Prasad J. Effect of high nitrate diet on thyroid glands in goats. Ind J Animal Sci 1983; 53:791-794.
7. Jahries G, Hesse VI, Schone LH and Mehnert E. Influence of nitrates and plant goitrgens on thyroid hormone, somated in status and growth of swine. Mj Vet Med 1986; 41:528-530.
8. Maekawa A, Ogiu T, Onodera H, Furuta K, Matsuoka C, Ohno Y, Odashima S. Carcinogenicity studies of sodium nitrite and sodium nitrate in F-344 rats. Food Chem Toxicol 1982; 20: 25-33 (Pubitemid 12082702)
9. Inai K, Aoki Y, Tokuoka S. Chronic toxicity of sodium nitrite in mice, with reference to its tumorigenicity. Gann 1979; 70: 203-208 (Pubitemid 9184703)
10. Mirvish SS, Bulay O, Runge RG, Patil K. Study of the carcinogenicity of large doses of dimethylnitramine. N-nitroso-L-proline, and sodium nitrite administered in drinking water to rats. J Natl Cancer Inst 1980; 64: 1435-1442 (Pubitemid 10109738)
11. Hirose M, Tanaka H, Takahashi S, Futakuchi M, Fukushima S, Ito N. Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model. Cancer Res 1993; 53: 32-37 (Pubitemid 23019373)
12. Aoyagi M, Matsukura N, Uchida E, Kawachi T, Sugimura T, Takayama S, Matsui M. Induction of liver tumors in Wistar rats by sodium nitrite given in pellet diets. J Natl Cancer Inst 1980; 65: 411-414 (Pubitemid 10087433)
13. Hecht SS. Approaches to cancer prevention based on an understanding of N-nitrosamine carcinogenesis. Proc Soc Exp Biol Med 1997; 216: 181-191 (Pubitemid 27449565)
14. Kawabe M, Takaba K, Yoshida Y, Hirose M. Effects of combined treatment with phenolic compounds and sodium nitrite on two-stage carcinogenesis and cell proliferation in the rat stomach. Jpn J Cancer Res 1994; 85: 17-25. (Pubitemid 24048286)
15. Yoshida Y, Hirose M, Takaba K, Kimura J, Ito N. Induction and promotion of forestomach tumors by sodium nitrite in combination with ascorbic acid or sodium ascorbate in rats with or without N-methyl-N-nitro-N-nitrosoguanidine pre-treatment. Int J Cancer 1994; 56: 124-128 (Pubitemid 24044804)
16. Craig W, Beck L. Phytochemicals: Health Protective Effects. Can J Diet Pract Res. 1999; 60:78-84.
17. Agarwal MK, Iqbal M, Athar M. Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention. Food Chem Toxicol. 2007; 45:1634-1640
18. Johnson MG and Vaughn RH. Death of Salmonella typhimurium and Escherichia coli in the presence of freshly reconstituted dehydrated garlic and onion. Appl Microbiol 1969; 17:903-905.
19. Hussain SP, Jannu LN and Roa AR. Chemopreventive action of garlic on methylcholanthrene induced carcinogenesis in the uterine cervix of mice. Cancer Lett 1990; 49:175-180.
20. Bordia A, Bansal HC, Arora SK and Singh SV. Effect of essential oils of garlic and onion on alimentary hyperlipidemia. Atherosclerosis 1975; 21:15-19.
21. Jain RC and Vjas CR. Garlic in alloxan induced diabetic rabbits. Am J Clin Nutr 1975; 28:684-685.
22. Amer M, Taha M and Tosson Z. The effect of aqueous garlic extract on the growth of dermatophytas. Inter Dermatol 1980; 19:285-287. (Pubitemid 10005072)
23. Bordia A and Verma SK. Effect of garlic feeding on regression of experimental atherosclerosis in rabbits. Artery 1980; 7:428-437. (Pubitemid 11145800)
24. Morihara N, Sumioka I, Ide N, Moriguchi T, Uda N, Kyo E. Aged garlic extract maintains cardiovascular homeostasis in mice and rats. J Nutr 2006;136:777S-781S. (Pubitemid 43363774)
25. Banerjee SK, Mukherjee PK and Maulik SK. Garlic as an antioxidant: the good, the bad and the ugly. Phytother Res 2003; 17:97-106. (Pubitemid 36262255)
26. Kohn MC, Melnick RL, Frank YE and Portier CJ. Pharmacokinetics of sodium nitrite-induced methemoglobinemia in the rat. DMD. 2002; 30:676-683. (Pubitemid 34579102)
27. Chen HW, Tsai CW, Yang JJ, Liu CT, Kuo WW and Lii CK. The combined effects of garlic oil and fish oil on the hepatic antioxidant and drug-metabolizing enzymes of rats. British J Nutr 2003; 89:189-200.
28. Trinder P. A colorimetric method for the determination of glucose. Ann Clin Biochem 1969; 6:24-26.
29. Van-Handle E. Estimation of glycogen in small amounts of tissue. Anal Biochem 1965; 11:256-262.
30. Reitman S and Frankel S. A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase. Am J Clin 1957; 28:56-63.
31. Belfield A, Goldberg DM. Revised assay for serum phenyl phosphatase activity using 4-amino-antipyrine. Enzyme 1971;12:561-573
32. Palton CJ and Crouch SR. Enzymatic determination of serum urea by modified Berthelot reaction. Anal Chem 1977; 49:464-469.
33. Henry RJ. Principles and Techniques. Clinical Chemistry, 2nd Ed. Harper and Row 1974:525.
34. Esteribauer H and Cheeseman K. Determination of aldehdic lipid peroxidation products: Malonaldehyde and 4- hydroxyonenal. Enzymol 1990; 186:407-421. (Pubitemid 20279982)
35. Prins HK and Loose JA. Glutathione "Chapter 4". In: Yunis JJ, ed. Biochemical Methods in Red Cell Genetics. London: Academic Press. 1969:126-129.
36. Aebi HE. Catalase ed HV. In: Bergmeyer HV, ed. Method of enzymatic analysis vol3. Berlin: Verlag Chemie. 1983:273-286.
37. Choi SY, Chung MJ and Sung NJ. Volatile N-nitrosamine inhibition after intake of Korean green tea and Maesil (Prunus mume SIEB. et ZACC.) extracts with an amine-rich diet in subjects ingesting nitrate. Food Chem Toxicol 2002; 40:949-957.
38. Aruoma OI. Free radicals, oxidative stress and antioxidants in human health and disease. J Am Oil Chem Soc 1998; 75:199-212. (Pubitemid 128607978)
39. Wiechetek M, Garwacki S, Karlik W, Lewicki J and Souffrant W. Effect of nitrite on ureagenesis and carbohydrate metabolism in isolated rat hepatocytes. Arch of Environ Contamin Toxicol 1992; 24:375-380. (Pubitemid 23087573)
40. Anil KB, Manju B, Giridhar S and Deepak B. Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem Biol Interact 2005; 20:101-102.
41. Liu CT, Hse H, Lii CK, Chen PS and Sheen LY. Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats. Eur J Pharmacol 2005; 516:165-173. (Pubitemid 40799353)
42. Eidi A, Eidi M and Esmaeili E. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin induced diabetic rats. Phytomedicine 2006; 13:624-629. (Pubitemid 44666394)
43. Eremin YN and Yocharina MG. Effect of nitrites on the state of thyroid gland in iodine deficiency and different diets. Vopr Pitan 1981; 5:60-62.
44. Kolpakov V, Gordon D and Kulik TJ. Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circ Res 1995; 76:305-309.
45. Kalantari H, Salehi M. The protective effect of garlic oil on hepatotoxicity induced by acetaminophen in mice and comparison with N-acetylcysteine. Saudi Med J 2001;22:1080-1084 (Pubitemid 34036773)
46. Hikino H, Tohkin M, Kiso Y, Namiki T, Nishimura S, Takeyama K. Antihepatotoxic Actions of Allium sativum Bulbs1. Planta Med 1986; 52:163-168. (Pubitemid 16088738)
47. Zurovsky Y and Haber C. Antioxidants attenuate endotoxin- generation induced acute renal failure in rats. Scand J Urol Nephrol 1995; 29:147-154.
48. Shahjahan M, Vani G and Shyamaladevi CS. Effect of Solanum trilobatum on the antioxidant status during diethyl nitrosamine induced and phenobarbital promoted hepatocarcinogenesis in rat. Chem Biological interact 2005; 156:113-123. (Pubitemid 41406234)
49. Popova MA and Popove CS. Effect of chemical agents on some enzyme activities and on the stability of membrane structures. Bulg J Vet Med 2005; 8:163-171.
50. Saravanan G and Prakash J. Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats. J Ethnopharmacol 2004; 94:155-158. (Pubitemid 38949817)
51. Pedraza-Chaverrí J, Maldonado PD, Barrera D, Cerón A, Medina- Campos ON, Hernández-Pando R. Protective effect of diallyl sulfide on oxidative stress and nephrotoxicity induced by gentamicin in rats. Mol Cell Biochem 2003; 254:125-130. (Pubitemid 37483747)