-
2
-
-
20144373679
-
-
Nallan, L.; Bauer, K. D.; Bendale, P.; Rivas, K.; Yokoyama, K.; Hornéy, C. P.; Pendyala, P. R.; Floyd, D.; Lombardo, L. J.; Williams, D. K.; Hamilton, A.; Sebti, S.; Windsor, W. T.; Weber, P. C.; Buckner, F. S.; Chakrabarti, D.; Gelb, M. H.; Van Voorhis, W. C. J. Med. Chem. 2005, 48, 3704.
-
(2005)
J. Med. Chem
, vol.48
, pp. 3704
-
-
Nallan, L.1
Bauer, K.D.2
Bendale, P.3
Rivas, K.4
Yokoyama, K.5
Hornéy, C.P.6
Pendyala, P.R.7
Floyd, D.8
Lombardo, L.J.9
Williams, D.K.10
Hamilton, A.11
Sebti, S.12
Windsor, W.T.13
Weber, P.C.14
Buckner, F.S.15
Chakrabarti, D.16
Gelb, M.H.17
Van Voorhis, W.C.18
-
3
-
-
0026347180
-
-
Kukla, M. J.; Breslin, H. J.; Diamond, C. J.; Grous, P. P.; Ho, C. Y.; Miranda, M.; Rodgers, J. D.; Sherrill, R. G.; De Clercq, E.; Pauwels, R.; Andries, K.; Moens, L. J.; Janssen, M. A. C.; Janssen, P. A. J. J. Med. Chem. 1991, 34, 3187.
-
(1991)
J. Med. Chem
, vol.34
, pp. 3187
-
-
Kukla, M.J.1
Breslin, H.J.2
Diamond, C.J.3
Grous, P.P.4
Ho, C.Y.5
Miranda, M.6
Rodgers, J.D.7
Sherrill, R.G.8
De Clercq, E.9
Pauwels, R.10
Andries, K.11
Moens, L.J.12
Janssen, M.A.C.13
Janssen, P.A.J.14
-
4
-
-
0034609805
-
-
(a) Hunt, J. T.; Ding, C. Z.; Batorsky, R.; Bednarz, M.; Bhide, R.; Cho, Y.; Chong, S.; Chao, S.; Gullo-Brown, J.; Guo, P.; Kim, S. H.; Lee, F. Y. F.; Leftheris, K.; Miller, A.; Mitt, T.; Patel, M.; Penhallow, B. A.; Ricca, C.; Rose, W. C.; Schmidt, R.; Slusarchyk, W. A.; Vite, G.; Manne, V. J. Med. Chem. 2000, 43, 3587.
-
(2000)
J. Med. Chem
, vol.43
, pp. 3587
-
-
Hunt, J.T.1
Ding, C.Z.2
Batorsky, R.3
Bednarz, M.4
Bhide, R.5
Cho, Y.6
Chong, S.7
Chao, S.8
Gullo-Brown, J.9
Guo, P.10
Kim, S.H.11
Lee, F.Y.F.12
Leftheris, K.13
Miller, A.14
Mitt, T.15
Patel, M.16
Penhallow, B.A.17
Ricca, C.18
Rose, W.C.19
Schmidt, R.20
Slusarchyk, W.A.21
Vite, G.22
Manne, V.23
more..
-
5
-
-
32944455992
-
-
(b) Sundberg, T. B.; Ney, G. M.; Subramanian, C.; Opipari, A. W.; Glick, G. D. Cancer Res. 2006, 66, 1775.
-
(2006)
Cancer Res
, vol.66
, pp. 1775
-
-
Sundberg, T.B.1
Ney, G.M.2
Subramanian, C.3
Opipari, A.W.4
Glick, G.D.5
-
6
-
-
33947714354
-
-
(c) Dourlat, J.; Liu, W.; Greash, N.; Garbay, C. Bioorg. Med. Chem. Lett. 2007, 17, 2527.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 2527
-
-
Dourlat, J.1
Liu, W.2
Greash, N.3
Garbay, C.4
-
9
-
-
17044414082
-
-
(a) Jiang, M. X.-W.; Warshakoon, N. C.; Miller, M. J. J. Org. Chem. 2005, 70, 2824.
-
(2005)
J. Org. Chem
, vol.70
, pp. 2824
-
-
Jiang, M.X.-W.1
Warshakoon, N.C.2
Miller, M.J.3
-
10
-
-
3042745573
-
-
(b) Li, F.; Brogan, J. B.; Gage, J. L.; Zhang, D.; Miller, M. J. J. Org. Chem. 2004, 69, 4538.
-
(2004)
J. Org. Chem
, vol.69
, pp. 4538
-
-
Li, F.1
Brogan, J.B.2
Gage, J.L.3
Zhang, D.4
Miller, M.J.5
-
11
-
-
0001364588
-
-
Mulvihill, M. J.; Surman, M. D.; Miller, M. J. J. Org. Chem. 1998, 63, 4874.
-
(1998)
J. Org. Chem
, vol.63
, pp. 4874
-
-
Mulvihill, M.J.1
Surman, M.D.2
Miller, M.J.3
-
12
-
-
0000143188
-
-
Dirat, O.; Kouklovsky, C.; Langlois, Y. Org. Lett. 1999, 1, 753.
-
(1999)
Org. Lett
, vol.1
, pp. 753
-
-
Dirat, O.1
Kouklovsky, C.2
Langlois, Y.3
-
13
-
-
64349115601
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-
Low yield due to difficulty with purification. The yield would be expected to be higher with polymer-bound Pd(0).
-
Low yield due to difficulty with purification. The yield would be expected to be higher with polymer-bound Pd(0).
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-
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14
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0037050428
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-
3/THF/Δ was 56%. See: Surman, M. D.; Mulvihill, M. J.; Miller, M. J. Org. Lett. 2002, 4, 139.
-
3/THF/Δ was 56%. See: Surman, M. D.; Mulvihill, M. J.; Miller, M. J. Org. Lett. 2002, 4, 139.
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15
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84869271376
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2 gave product 5 as a pure white powder.
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2 gave product 5 as a pure white powder.
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-
-
-
16
-
-
0342894825
-
-
Fukuyama, T.; Cheung, M.; Jow, C.; Hidai, U.; Kant, T. Tetrahedron Lett. 1997, 38, 5831.
-
(1997)
Tetrahedron Lett
, vol.38
, pp. 5831
-
-
Fukuyama, T.1
Cheung, M.2
Jow, C.3
Hidai, U.4
Kant, T.5
-
17
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64349100928
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-
Decomposition of mercaptoacetic acid due to oxidation and occasional deprotection of TBS group proved problematic
-
Decomposition of mercaptoacetic acid due to oxidation and occasional deprotection of TBS group proved problematic.
-
-
-
-
18
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64349089019
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-
Several bases, solvents, and temperatures were exhaustively explored
-
Several bases, solvents, and temperatures were exhaustively explored.
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-
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19
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64349103456
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The procedure for the preparation of iron free silica gel may be found in the Supporting Information
-
The procedure for the preparation of iron free silica gel may be found in the Supporting Information.
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20
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58149291860
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Cesario, C.; Tardibono, L.; Miller, M. J. J. Org. Chem. 2009, 74, 448.
-
(2009)
J. Org. Chem
, vol.74
, pp. 448
-
-
Cesario, C.1
Tardibono, L.2
Miller, M.J.3
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