A genetic diagnosis of HNF1A diabetes alters treatment and improves glycaemic control in the majority of insulin-treated patients

Diabetic Medicine

Volumn 26, Issue 4, 2009, Pages 437-441

  Shepherd, Maggie ^a   Shields, B ^a   Ellard, S ^a,b   Rubio Cabezas, O ^a,c   Hattersley, A T ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

^c HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

Author keywords

HNF1A; Maturity onset diabetes of the young; Monogenic diabetes; Sulphonylurea sensitivity

Indexed keywords

GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLIPIZIDE; HEMOGLOBIN A1C; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; INSULIN; METFORMIN; SULFONYLUREA DERIVATIVE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; DISEASE DURATION; DOSE CALCULATION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN TREATMENT; MALE; MONOGENIC DISORDER; MONOTHERAPY; PATIENT ASSESSMENT; TREATMENT DURATION; TREATMENT OUTCOME;

BLOOD GLUCOSE; DIABETES MELLITUS; FEMALE; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MUTATION; PRACTICE GUIDELINES AS TOPIC; SULFONYLUREA COMPOUNDS;

EID: 64249170094     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2009.02690.x     Document Type: Article

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