메뉴 건너뛰기




Volumn 20, Issue 1, 2009, Pages 86-90

Rheumatoid arthritis and periodontitis: Biological links and the emergence of dual purpose therapies

Author keywords

Biological linkages; Periodontitis; Rheumatoid arthritis

Indexed keywords

ANTIRHEUMATIC AGENT; AUTACOID; BISPHOSPHONIC ACID DERIVATIVE; BONE DENSITY CONSERVATION AGENT; IMMUNOSUPPRESSIVE AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; TETRACYCLINE DERIVATIVE;

EID: 64249170084     PISSN: 09709290     EISSN: 1998359X     Source Type: Journal    
DOI: 10.4103/0970-9290.49070     Document Type: Review
Times cited : (14)

References (41)
  • 1
    • 16844385090 scopus 로고    scopus 로고
    • Epidemiology of adult rheumatoid arthritis
    • Alamanos Y, Drosos AA. Epidemiology of adult rheumatoid arthritis. Autoimmun Rev 2005;4:130-6.
    • (2005) Autoimmun Rev , vol.4 , pp. 130-136
    • Alamanos, Y.1    Drosos, A.A.2
  • 2
    • 0017510391 scopus 로고
    • Collagenases at sites of cartilage erosion in the rheumatoid joint
    • Woolley DE, Crossley MJ, Evanson JM. Collagenases at sites of cartilage erosion in the rheumatoid joint. Arthritis Rheum 1977;20:1231-9.
    • (1977) Arthritis Rheum , vol.20 , pp. 1231-1239
    • Woolley, D.E.1    Crossley, M.J.2    Evanson, J.M.3
  • 3
    • 0034930640 scopus 로고    scopus 로고
    • Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint
    • Haynes DR, Crotti TN, Capone M, Bain GI, Atkin GJ, Findlay DM. Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. Rheumatology (Oxford) 2001;40:623-30.
    • (2001) Rheumatology (Oxford) , vol.40 , pp. 623-630
    • Haynes, D.R.1    Crotti, T.N.2    Capone, M.3    Bain, G.I.4    Atkin, G.J.5    Findlay, D.M.6
  • 4
    • 0026802287 scopus 로고
    • Detection of cytokines at the cartilage/ pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair
    • Chu CQ, Field M, Allard S, Abney E, Feldmann M, Maini RN. Detection of cytokines at the cartilage/ pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair. Br J Rheumatol 1992;31:653-61.
    • (1992) Br J Rheumatol , vol.31 , pp. 653-661
    • Chu, C.Q.1    Field, M.2    Allard, S.3    Abney, E.4    Feldmann, M.5    Maini, R.N.6
  • 5
    • 0030278552 scopus 로고    scopus 로고
    • Periodontal disease: Epidemiology
    • Papapanau PN. Periodontal disease: Epidemiology. Ann Periodontol 1996;1:1-36.
    • (1996) Ann Periodontol , vol.1 , pp. 1-36
    • Papapanau, P.N.1
  • 6
    • 0037268875 scopus 로고    scopus 로고
    • Perspective of cytokine regulation for periodontal treatment: Fibroblast biology
    • Takashiba S, Naruishi K, Murayama Y. Perspective of cytokine regulation for periodontal treatment: Fibroblast biology. J Periodont 2003;74:103- 10.
    • (2003) J Periodont , vol.74 , pp. 103-110
    • Takashiba, S.1    Naruishi, K.2    Murayama, Y.3
  • 7
    • 0034169263 scopus 로고    scopus 로고
    • Is there a relationship between rheumatoid arthritis and periodontal disease?
    • Mercado F, Marshall RI, Klestov AC, Bartold PM. Is there a relationship between rheumatoid arthritis and periodontal disease? J Clin Periodontol 2000;27:267-72.
    • (2000) J Clin Periodontol , vol.27 , pp. 267-272
    • Mercado, F.1    Marshall, R.I.2    Klestov, A.C.3    Bartold, P.M.4
  • 9
    • 0030203872 scopus 로고    scopus 로고
    • Systemic antibiotics in periodontics
    • Slots J. Systemic antibiotics in periodontics. J Periodont 1996;67:831-8.
    • (1996) J Periodont , vol.67 , pp. 831-838
    • Slots, J.1
  • 10
    • 25144494114 scopus 로고    scopus 로고
    • Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis
    • Ogrendik M, Kokino S, Ozdemir F, Bird PS, Hamlet S. Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis. MedGenMed 2005;7:2-10.
    • (2005) MedGenMed , vol.7 , pp. 2-10
    • Ogrendik, M.1    Kokino, S.2    Ozdemir, F.3    Bird, P.S.4    Hamlet, S.5
  • 11
    • 27144482048 scopus 로고    scopus 로고
    • Hypothesis: The humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis
    • Rosenstein ED, Greenwald RA, Kushner LJ, Weissmann G. Hypothesis: The humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis. Inflammation 2004;28:311-8.
    • (2004) Inflammation , vol.28 , pp. 311-318
    • Rosenstein, E.D.1    Greenwald, R.A.2    Kushner, L.J.3    Weissmann, G.4
  • 12
    • 0032528185 scopus 로고    scopus 로고
    • Enhanced expression of heatshock protein 70 (hsp 70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue: Differential regulation of expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and anti-inflammatory drugs
    • Schett G, Redlich K, Xu Q, Bizan P, Gröger M, Tohidast-Akrad M, et al. Enhanced expression of heatshock protein 70 (hsp 70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue: Differential regulation of expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and anti-inflammatory drugs. J Clin Invest 1998;102:302-11.
    • (1998) J Clin Invest , vol.102 , pp. 302-311
    • Schett, G.1    Redlich, K.2    Xu, Q.3    Bizan, P.4    Gröger, M.5    Tohidast-Akrad, M.6
  • 13
    • 33745686201 scopus 로고    scopus 로고
    • The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitopes
    • Marotte H, Farge P, Gaudin P, Alexandre C, Mougin B, Miossec P. The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitopes. Ann Rheum Dis 2006;65:905-9.
    • (2006) Ann Rheum Dis , vol.65 , pp. 905-909
    • Marotte, H.1    Farge, P.2    Gaudin, P.3    Alexandre, C.4    Mougin, B.5    Miossec, P.6
  • 14
    • 30944455953 scopus 로고    scopus 로고
    • Cytokine profiles in peripheral blood and whole blood cell cultures associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis
    • Havemose-Poulsen A, Sørensen LK, Stoltze K, Bendtzen K, Holmstrup P. Cytokine profiles in peripheral blood and whole blood cell cultures associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2005;76:2276-85.
    • (2005) J Periodontol , vol.76 , pp. 2276-2285
    • Havemose-Poulsen, A.1    Sørensen, L.K.2    Stoltze, K.3    Bendtzen, K.4    Holmstrup, P.5
  • 15
    • 33947678169 scopus 로고    scopus 로고
    • Polymorphism within the IL-1 gene cluster: Effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis
    • Havemose-Poulsen A, Sørensen LK, Bendtzen K, Holmstrup P. Polymorphism within the IL-1 gene cluster: Effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2007;78:475-92.
    • (2007) J Periodontol , vol.78 , pp. 475-492
    • Havemose-Poulsen, A.1    Sørensen, L.K.2    Bendtzen, K.3    Holmstrup, P.4
  • 16
    • 17444424970 scopus 로고    scopus 로고
    • Experimental arthritis in rats induces biomarkers of periodontitis which are ameliorated by gene therapy with tissue inhibitor of matrix metalloproteinases
    • Rammamurthy NS, Greenwald RA, Celiker MY, Shi EY. Experimental arthritis in rats induces biomarkers of periodontitis which are ameliorated by gene therapy with tissue inhibitor of matrix metalloproteinases. J Periodontol 2005;76:229-33.
    • (2005) J Periodontol , vol.76 , pp. 229-233
    • Rammamurthy, N.S.1    Greenwald, R.A.2    Celiker, M.Y.3    Shi, E.Y.4
  • 17
    • 0021677785 scopus 로고
    • Tetracyclins inhibit tissue collagenase activity: A new mechanism in the treatment of periodontal disease
    • Golub LM, Rammamurthy NS, McNamara TF, Gomes B, Wolff M, Casino A, et al. Tetracyclins inhibit tissue collagenase activity: A new mechanism in the treatment of periodontal disease. J Periodontol Res 1984;19:651-5.
    • (1984) J Periodontol Res , vol.19 , pp. 651-655
    • Golub, L.M.1    Rammamurthy, N.S.2    McNamara, T.F.3    Gomes, B.4    Wolff, M.5    Casino, A.6
  • 18
    • 0027292516 scopus 로고
    • Blocking periodontal disease progression by inhibiting tissue destructive enzymes: A potential therapeutic role for tetracyclins and their chemically modified analogues
    • Rifkin BR, Vermillo AT, Golub LM. Blocking periodontal disease progression by inhibiting tissue destructive enzymes: A potential therapeutic role for tetracyclins and their chemically modified analogues. J Periodontol 1993;64:819-23.
    • (1993) J Periodontol , vol.64 , pp. 819-823
    • Rifkin, B.R.1    Vermillo, A.T.2    Golub, L.M.3
  • 19
    • 1542653032 scopus 로고    scopus 로고
    • Effects of sub-antimicrobial dose of doxycycline therapy on cervicular fluid MMP-8 and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis
    • Choi DH, Moon IS, Choi BK, Park JW, Kim YS, Choi SH, et al. Effects of sub-antimicrobial dose of doxycycline therapy on cervicular fluid MMP-8 and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis. J Periodontol Res 2004;39:20-6.
    • (2004) J Periodontol Res , vol.39 , pp. 20-26
    • Choi, D.H.1    Moon, I.S.2    Choi, B.K.3    Park, J.W.4    Kim, Y.S.5    Choi, S.H.6
  • 20
    • 33746742984 scopus 로고    scopus 로고
    • Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with early rheumatoid arthritis
    • Fiedorczyk M, Klimiuk PA, Sierakowski S, Gindzienska-Sieskiewicz E, Chwiecko J. Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with early rheumatoid arthritis. J Rheumatol 2006;33:1523-9.
    • (2006) J Rheumatol , vol.33 , pp. 1523-1529
    • Fiedorczyk, M.1    Klimiuk, P.A.2    Sierakowski, S.3    Gindzienska-Sieskiewicz, E.4    Chwiecko, J.5
  • 21
    • 0141642241 scopus 로고    scopus 로고
    • Should tetracycline treatment be used more extensively for rheumatoid arthritis? Meta analysis demonstrates clinical benefit with reduction in disease activity
    • Stone M, Fortin PR, Pacheco-Tena C, Inman RD. Should tetracycline treatment be used more extensively for rheumatoid arthritis? Meta analysis demonstrates clinical benefit with reduction in disease activity. J Rheumatol 2003;30:2112-22.
    • (2003) J Rheumatol , vol.30 , pp. 2112-2122
    • Stone, M.1    Fortin, P.R.2    Pacheco-Tena, C.3    Inman, R.D.4
  • 22
    • 33748638853 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation
    • Sorsa T, Tjaderhane L, Konttinen YT, Lauhio A, Salo T, Lee HM, et al. Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Ann Med 2006;38:306-21.
    • (2006) Ann Med , vol.38 , pp. 306-321
    • Sorsa, T.1    Tjaderhane, L.2    Konttinen, Y.T.3    Lauhio, A.4    Salo, T.5    Lee, H.M.6
  • 23
    • 0032197685 scopus 로고    scopus 로고
    • Safety and efficacy of sub-antimicrobial dose of doxycycline therapy in patients with adult periodontitis
    • Ciancio S, Ashley R. Safety and efficacy of sub-antimicrobial dose of doxycycline therapy in patients with adult periodontitis. Adv Dent Res 1998;12:27-31.
    • (1998) Adv Dent Res , vol.12 , pp. 27-31
    • Ciancio, S.1    Ashley, R.2
  • 24
    • 0031665965 scopus 로고    scopus 로고
    • Bone resorption caused by three periodontolal pathogens in vivo in mice is mediated in part by prostaglandins
    • Zubery Y, Dunstan CR, Stony BM, Kesavalu L, Ebersole JL, Holt SC, et al. Bone resorption caused by three periodontolal pathogens in vivo in mice is mediated in part by prostaglandins. Infect Immun 1998;66:4158-62.
    • (1998) Infect Immun , vol.66 , pp. 4158-4162
    • Zubery, Y.1    Dunstan, C.R.2    Stony, B.M.3    Kesavalu, L.4    Ebersole, J.L.5    Holt, S.C.6
  • 25
    • 0019379327 scopus 로고    scopus 로고
    • EL attar TM, Lin HS. Prostaglandins in gingival of patients with periodontal disease. J Periodontol 1981;53:16-20.
    • EL attar TM, Lin HS. Prostaglandins in gingival of patients with periodontal disease. J Periodontol 1981;53:16-20.
  • 26
    • 0031310840 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs as adjuncts in the management of periodontal diseases and peri-implantitis
    • Salvi GE, Williams RC, Offenbacher S. Nonsteroidal anti-inflammatory drugs as adjuncts in the management of periodontal diseases and peri-implantitis. Curr Opin Periodontol 1997;4:51-8.
    • (1997) Curr Opin Periodontol , vol.4 , pp. 51-58
    • Salvi, G.E.1    Williams, R.C.2    Offenbacher, S.3
  • 27
    • 0032564358 scopus 로고    scopus 로고
    • Mode of action of aspirin-like drugs: Salicylates inhibit erk activation and integrin dependent neutrophil adhesion
    • Pillinger MH, Capodici C, Rosenthal P, Kheterpal N, Hanft S, Philips MR, et al. Mode of action of aspirin-like drugs: Salicylates inhibit erk activation and integrin dependent neutrophil adhesion. Proc Natl Acad Sci USA 1998;95:14540-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14540-14545
    • Pillinger, M.H.1    Capodici, C.2    Rosenthal, P.3    Kheterpal, N.4    Hanft, S.5    Philips, M.R.6
  • 28
    • 4644289081 scopus 로고    scopus 로고
    • Antiinflammatory drugs and tumor necrosis factor alpha production from monocytes: Role of transcription factor NF-Kappa B and implication for rheumatoid arthritis therapy
    • Gunella G, Bardelli C, Spina S, Fresu LG, Viano I, Brunelleschi S. Antiinflammatory drugs and tumor necrosis factor alpha production from monocytes: Role of transcription factor NF-Kappa B and implication for rheumatoid arthritis therapy. Eur J Pharmacol 2004;6:199-208.
    • (2004) Eur J Pharmacol , vol.6 , pp. 199-208
    • Gunella, G.1    Bardelli, C.2    Spina, S.3    Fresu, L.G.4    Viano, I.5    Brunelleschi, S.6
  • 29
    • 33745900256 scopus 로고    scopus 로고
    • Bisphosphonate therapy in rheumatoid arthritis
    • Breuil V, Euller-Ziegler L. Bisphosphonate therapy in rheumatoid arthritis. Joint Bone Spine 2006;73:349-54.
    • (2006) Joint Bone Spine , vol.73 , pp. 349-354
    • Breuil, V.1    Euller-Ziegler, L.2
  • 30
    • 33646484359 scopus 로고    scopus 로고
    • Jarrrtt SJ, Conaghan Sloan VS, Papanastasiou P, Ortmann CE, O.Connor PJ, et al. Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis. Arthritis Rheum 2006;54:1410-4.
    • Jarrrtt SJ, Conaghan PG, Sloan VS, Papanastasiou P, Ortmann CE, O.Connor PJ, et al. Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis. Arthritis Rheum 2006;54:1410-4.
  • 31
    • 23044488738 scopus 로고    scopus 로고
    • Bisphosphonate therapy improves the outcome of conventional periodontal treatment: Results of a 12-month randomized placebo controlled study
    • Lane N, Armitage GC, Loomer P, Hsieh S, Majumdar S, Wang HY, et al. Bisphosphonate therapy improves the outcome of conventional periodontal treatment: Results of a 12-month randomized placebo controlled study. J Periodontol 2005;76:1113-22.
    • (2005) J Periodontol , vol.76 , pp. 1113-1122
    • Lane, N.1    Armitage, G.C.2    Loomer, P.3    Hsieh, S.4    Majumdar, S.5    Wang, H.Y.6
  • 32
    • 0034524919 scopus 로고    scopus 로고
    • The clinical and microbiological effects of systemic ornidazole in sites with and without subgingival debridement in early-onset periodontitis patients
    • Kamma JJ, Nakou M, Mitsis FJ. The clinical and microbiological effects of systemic ornidazole in sites with and without subgingival debridement in early-onset periodontitis patients. J Periodontol 2000;71:1862-73.
    • (2000) J Periodontol , vol.71 , pp. 1862-1873
    • Kamma, J.J.1    Nakou, M.2    Mitsis, F.J.3
  • 33
    • 33646180678 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with ornidazole: A randomized double blind, placebo-controlled study
    • Ogrendik M, Hakguder A, Keser N. Treatment of rheumatoid arthritis with ornidazole: A randomized double blind, placebo-controlled study. Rheumatology (Oxford) 2006;45:636-7.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 636-637
    • Ogrendik, M.1    Hakguder, A.2    Keser, N.3
  • 34
    • 0026824718 scopus 로고
    • Host modulation with tetracyclins and their chemically modified analogues
    • Golub LM, Soummalainen K, Sorsa T. Host modulation with tetracyclins and their chemically modified analogues. Curr Opin Dent 1992;2:80-90.
    • (1992) Curr Opin Dent , vol.2 , pp. 80-90
    • Golub, L.M.1    Soummalainen, K.2    Sorsa, T.3
  • 35
    • 31344476048 scopus 로고    scopus 로고
    • Tetracyclins: Nonantibiotic properties and their clinical implications
    • Sapadin AN, Fleischmajer R. Tetracyclins: Nonantibiotic properties and their clinical implications. J Am Acad Dermatol 2006;54:258-65.
    • (2006) J Am Acad Dermatol , vol.54 , pp. 258-265
    • Sapadin, A.N.1    Fleischmajer, R.2
  • 36
    • 3242707823 scopus 로고    scopus 로고
    • Chemically modified tetracyclins act through multiple mechanisms directly on osteoclast precursors
    • Holmes SG, Still K, Buttle DJ, Bishop NJ, Grabowski PS. Chemically modified tetracyclins act through multiple mechanisms directly on osteoclast precursors. Bone 2004;35:471-8.
    • (2004) Bone , vol.35 , pp. 471-478
    • Holmes, S.G.1    Still, K.2    Buttle, D.J.3    Bishop, N.J.4    Grabowski, P.S.5
  • 37
    • 0034887225 scopus 로고    scopus 로고
    • D.Agostino P, Ferlazzo V, Milano S, La Rosa M, Di Bella G, Caruso R, et al. Anti-inflammatory effects of chemically modified tetracyclines by the inhibition of nitric oxide and interleukin-12 synthesis in J774 cell line. Int Immunopharmacol 2001;1:1765-76.
    • D.Agostino P, Ferlazzo V, Milano S, La Rosa M, Di Bella G, Caruso R, et al. Anti-inflammatory effects of chemically modified tetracyclines by the inhibition of nitric oxide and interleukin-12 synthesis in J774 cell line. Int Immunopharmacol 2001;1:1765-76.
  • 38
    • 4143100136 scopus 로고    scopus 로고
    • Differential expression of RANKL and OSteoprotegerin in gingival crevicular fluid of patients with periodontitis
    • Mogi M, Otogoto J, Ota N, Togari A. Differential expression of RANKL and OSteoprotegerin in gingival crevicular fluid of patients with periodontitis. J Dent Res 2004;83:166-9.
    • (2004) J Dent Res , vol.83 , pp. 166-169
    • Mogi, M.1    Otogoto, J.2    Ota, N.3    Togari, A.4
  • 39
    • 0038746729 scopus 로고    scopus 로고
    • RANKL and RANK as novel therapeutic targets for arthritis
    • Nakashima T, Wada T, Penninger JM. RANKL and RANK as novel therapeutic targets for arthritis. Curr Opin Rheumatol 2003;15:280-7.
    • (2003) Curr Opin Rheumatol , vol.15 , pp. 280-287
    • Nakashima, T.1    Wada, T.2    Penninger, J.M.3
  • 40
    • 0037242711 scopus 로고    scopus 로고
    • Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthrithropathies and osteoarthritis and normal controls
    • Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, et al. Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthrithropathies and osteoarthritis and normal controls. Rheumatology 2003;42:123-34.
    • (2003) Rheumatology , vol.42 , pp. 123-134
    • Haynes, D.R.1    Barg, E.2    Crotti, T.N.3    Holding, C.4    Weedon, H.5    Atkins, G.J.6
  • 41
    • 33747109877 scopus 로고    scopus 로고
    • Conjugated linoleic acid inhibits osteoclast differentiation of RAW264.7 cells by modulating RANKL signaling
    • Rahman MM, Bhattacharya A, Fernandes G. Conjugated linoleic acid inhibits osteoclast differentiation of RAW264.7 cells by modulating RANKL signaling. J Lipid Res 2006;47:1739-48.
    • (2006) J Lipid Res , vol.47 , pp. 1739-1748
    • Rahman, M.M.1    Bhattacharya, A.2    Fernandes, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.