A comparison of the pharmacokinetics of two different formulations of extended-release niacin

Current Medical Research and Opinion

Volumn 25, Issue 1, 2009, Pages 15-22

  Lauring, B ^a   Rosko, K ^a   Luo, W L ^a   Wenning, L ^a   Kissling, J ^b   Roupe, K ^b   Paolini, J F ^a   Wagner, J ^a   Lai, E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MDS Inc   (Canada)

Author keywords

Niacin; Niacin extended release; Nicotinuric acid; Pharmacokinetics

Indexed keywords

DRUG METABOLITE; METHYLNICOTINAMIDE; N METHYL 2 PYRIDONE 5 CARBOXAMIDE; NICOTINIC ACID; NICOTINURIC ACID; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DELAYED DRUG RELEASE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG COATING; DRUG DOSAGE FORM COMPARISON; DRUG EXCRETION; DRUG FORMULATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SOLID PHASE EXTRACTION; TABLET; TANDEM MASS SPECTROMETRY; URINALYSIS; URINARY EXCRETION; BIOAVAILABILITY; BLOOD; DELAYED RELEASE FORMULATION; MIDDLE AGED; URINE;

ADULT; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; NIACIN;

EID: 64249122748     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007990802569034     Document Type: Article

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