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Volumn 123, Issue 1, 2009, Pages 19-28

Immunotherapy in head and neck cancer: Current practice and future possibilities

Author keywords

Head and Neck Neoplasms; Immunotherapy; Squamous Carcinoma

Indexed keywords

BEVACIZUMAB; CETUXIMAB; CYCLOPHOSPHAMIDE; DENDRITIC CELL VACCINE; DNA VACCINE; ERLOTINIB; GEFITINIB; INDOMETACIN; INTERLEUKIN 10; INTERLEUKIN 4; LEUKOCYTE ANTIGEN; MULTIVITAMIN; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT INTERLEUKIN 12; RITUXIMAB; TRASTUZUMAB; TUMOR ANTIGEN; TUMOR CELL VACCINE; ZINC; CANCER VACCINE; CYTOKINE; MONOCLONAL ANTIBODY;

EID: 64249084710     PISSN: 00222151     EISSN: 17485460     Source Type: Journal    
DOI: 10.1017/S0022215108003356     Document Type: Review
Times cited : (13)

References (75)
  • 3
    • 33745236047 scopus 로고    scopus 로고
    • Apoptosis: The suicide solution in cancer treatment and chemoprevention
    • Sykiotis GP, Papavassiliou AG. Apoptosis: the suicide solution in cancer treatment and chemoprevention. Expert Opin Investig Drugs 2006;15:575-7
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 575-577
    • Sykiotis, G.P.1    Papavassiliou, A.G.2
  • 5
    • 24944582969 scopus 로고    scopus 로고
    • Interpreting epithelial cancer biology in the context of stem cells: Tumor properties and therapeutic implications
    • Miller SJ, Lavker RM, Sun TT. Interpreting epithelial cancer biology in the context of stem cells: tumor properties and therapeutic implications. Biochim Biophys Acta 2005;1756:25 - 52
    • (2005) Biochim Biophys Acta , vol.1756 , pp. 25-52
    • Miller, S.J.1    Lavker, R.M.2    Sun, T.T.3
  • 7
    • 34249680198 scopus 로고    scopus 로고
    • Investigation of IL-10, IL-12 and IL-18 levels in patients with head and neck cancer
    • Jebreel A, Mistry D, Loke D, Dunn G, Hough V, Oliver K et al. Investigation of IL-10, IL-12 and IL-18 levels in patients with head and neck cancer. J Laryngol Otol 2007;121:246 - 52
    • (2007) J Laryngol Otol , vol.121 , pp. 246-252
    • Jebreel, A.1    Mistry, D.2    Loke, D.3    Dunn, G.4    Hough, V.5    Oliver, K.6
  • 8
    • 21344432364 scopus 로고    scopus 로고
    • Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus
    • O'Riordan JM, Abdel-Latif MM, Ravi N, McNamara D, Byrne PJ, McDonald GS et al. Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Gastroenterol 2005; 100:1257-64
    • (2005) Am J Gastroenterol , vol.100 , pp. 1257-1264
    • O'Riordan, J.M.1    Abdel-Latif, M.M.2    Ravi, N.3    McNamara, D.4    Byrne, P.J.5    McDonald, G.S.6
  • 9
    • 22944439078 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 in patients with primary head and neck squamous cell carcinoma
    • Riedel F, Zaiss I, Herzog D, Gotte K, Naim R, Hormann K. Serum levels of interleukin-6 in patients with primary head and neck squamous cell carcinoma. Anticancer Res 2005;25:2761-5
    • (2005) Anticancer Res , vol.25 , pp. 2761-2765
    • Riedel, F.1    Zaiss, I.2    Herzog, D.3    Gotte, K.4    Naim, R.5    Hormann, K.6
  • 10
    • 0142010673 scopus 로고    scopus 로고
    • Lymphocyte subsets and T(h)1/T(h)2 immune responses in patients with adenocarcinoma of the oesophagus or oesophago- gastric junction: Relation to pTNM stage and clinical outcome
    • van Sandick JW, Boermeester MA, Gisbertz SS, ten Berge IJ, Out TA, van der Pouw Kraan TC et al. Lymphocyte subsets and T(h)1/T(h)2 immune responses in patients with adenocarcinoma of the oesophagus or oesophago- gastric junction: relation to pTNM stage and clinical outcome. Cancer Immunol Immunother 2003;52:617-24
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 617-624
    • van Sandick, J.W.1    Boermeester, M.A.2    Gisbertz, S.S.3    ten Berge, I.J.4    Out, T.A.5    van der Pouw Kraan, T.C.6
  • 11
    • 0034742512 scopus 로고    scopus 로고
    • IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas
    • Wolf JS, Chen Z, Dong G, Sunwoo JB, Bancroft CC, Capo DE et al. IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. Clin Cancer Res 2001;7:1812-20
    • (2001) Clin Cancer Res , vol.7 , pp. 1812-1820
    • Wolf, J.S.1    Chen, Z.2    Dong, G.3    Sunwoo, J.B.4    Bancroft, C.C.5    Capo, D.E.6
  • 12
    • 0038712135 scopus 로고    scopus 로고
    • Disregulated expression of the Th2 cytokine gene in patients with intraoral squamous cell carcinoma
    • Agarwal A, Rani M, Saha GK, Valarmathi TM, Bahadur S, Mohanti BK et al. Disregulated expression of the Th2 cytokine gene in patients with intraoral squamous cell carcinoma. Immunol Invest 2003;32:17-30
    • (2003) Immunol Invest , vol.32 , pp. 17-30
    • Agarwal, A.1    Rani, M.2    Saha, G.K.3    Valarmathi, T.M.4    Bahadur, S.5    Mohanti, B.K.6
  • 13
    • 7444224857 scopus 로고    scopus 로고
    • Modulation of Th1 and Th2 cytokine profiles and their association with advanced head and neck squamous cell carcinoma
    • Sparano A, Lathers DM, Achille N, Petruzzelli GJ, Young MR. Modulation of Th1 and Th2 cytokine profiles and their association with advanced head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2004;131:573- 6
    • (2004) Otolaryngol Head Neck Surg , vol.131 , pp. 573-576
    • Sparano, A.1    Lathers, D.M.2    Achille, N.3    Petruzzelli, G.J.4    Young, M.R.5
  • 14
    • 33645380390 scopus 로고    scopus 로고
    • Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma
    • Ogura M, Morishima Y, Kagami Y, Watanabe T, Itoh K, Igarashi T et al. Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma. Cancer Sci 2006;97:305-12
    • (2006) Cancer Sci , vol.97 , pp. 305-312
    • Ogura, M.1    Morishima, Y.2    Kagami, Y.3    Watanabe, T.4    Itoh, K.5    Igarashi, T.6
  • 15
    • 0036179603 scopus 로고    scopus 로고
    • Trastuzumab: A review of its use in the treatment of metastatic breast cancer overexpressing HER2
    • McKeage K, Perry CM. Trastuzumab: a review of its use in the treatment of metastatic breast cancer overexpressing HER2. Drugs 2002;62:209- 43
    • (2002) Drugs , vol.62 , pp. 209-243
    • McKeage, K.1    Perry, C.M.2
  • 16
    • 0037215106 scopus 로고    scopus 로고
    • Targeting epidermal growth factor receptor in head and neck cancer
    • Ford AC, Grandis JR. Targeting epidermal growth factor receptor in head and neck cancer. Head Neck 2003;25:67-73
    • (2003) Head Neck , vol.25 , pp. 67-73
    • Ford, A.C.1    Grandis, J.R.2
  • 17
    • 67649244994 scopus 로고    scopus 로고
    • Coico R, Sunshine G, Benjamini E. Immunology: A short course, Chapter 19 Tumour Immunology pp273-85. 5th Ed. (2003), New Jersey, USA John Wiley & Sons Inc. 18 Li G, Ali SA, McArdle SE, Mian S, Ahmad M, Miles A et al. Immunity to tumour antigens. Curr Pharm Des 2005;11:3501-9
    • Coico R, Sunshine G, Benjamini E. Immunology: A short course, Chapter 19 Tumour Immunology pp273-85. 5th Ed. (2003), New Jersey, USA John Wiley & Sons Inc. 18 Li G, Ali SA, McArdle SE, Mian S, Ahmad M, Miles A et al. Immunity to tumour antigens. Curr Pharm Des 2005;11:3501-9
  • 18
    • 0038274027 scopus 로고    scopus 로고
    • Identification of NY-ESO-1, MAGE-1, and MAGE-3 in head and neck squamous cell carcinoma
    • Kienstra MA, Neel HB, Strome SE, Roche P. Identification of NY-ESO-1, MAGE-1, and MAGE-3 in head and neck squamous cell carcinoma. Head Neck 2003;25:457-63
    • (2003) Head Neck , vol.25 , pp. 457-463
    • Kienstra, M.A.1    Neel, H.B.2    Strome, S.E.3    Roche, P.4
  • 19
    • 17544382860 scopus 로고    scopus 로고
    • Expression of the MAGE 3 gene product in squamous cell carcinomas of the head and neck
    • Lee KD, Chang HK, Jo YK, Kim BS, Lee BH, Lee YW et al. Expression of the MAGE 3 gene product in squamous cell carcinomas of the head and neck. Anticancer Res 1999: 19:5037 -42
    • (1999) Anticancer Res , vol.19 , pp. 5037-5042
    • Lee, K.D.1    Chang, H.K.2    Jo, Y.K.3    Kim, B.S.4    Lee, B.H.5    Lee, Y.W.6
  • 20
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245 - 52
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 21
    • 0031570045 scopus 로고    scopus 로고
    • In vivo migration of dendritic cells differentiated in vitro: A chimpanzee model
    • Barratt-Boyes SM, Watkins SC, Finn OJ. In vivo migration of dendritic cells differentiated in vitro: a chimpanzee model. J Immunol 1997;158:4543-7
    • (1997) J Immunol , vol.158 , pp. 4543-4547
    • Barratt-Boyes, S.M.1    Watkins, S.C.2    Finn, O.J.3
  • 22
    • 0036379771 scopus 로고    scopus 로고
    • A sense of tumour for the immune system
    • Todryk S. A sense of tumour for the immune system. Immunology 2002;107:1-4
    • (2002) Immunology , vol.107 , pp. 1-4
    • Todryk, S.1
  • 23
    • 33745291827 scopus 로고    scopus 로고
    • Breaking tolerance to tumors with dendritic cell-based immunotherapy
    • Mende I, Engleman EG. Breaking tolerance to tumors with dendritic cell-based immunotherapy. Ann N Y Acad Sci 2005;1058:96-104
    • (2005) Ann N Y Acad Sci , vol.1058 , pp. 96-104
    • Mende, I.1    Engleman, E.G.2
  • 24
    • 10744229153 scopus 로고    scopus 로고
    • Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells
    • Andre F, Chaput N, Schartz NE, Flament C, Aubert N, Bernard J et al. Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol 2004;172:2126-36
    • (2004) J Immunol , vol.172 , pp. 2126-2136
    • Andre, F.1    Chaput, N.2    Schartz, N.E.3    Flament, C.4    Aubert, N.5    Bernard, J.6
  • 26
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
    • Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 2001;166:678- 89
    • (2001) J Immunol , vol.166 , pp. 678-689
    • Almand, B.1    Clark, J.I.2    Nikitina, E.3    van Beynen, J.4    English, N.R.5    Knight, S.C.6
  • 27
    • 0027506726 scopus 로고
    • Depressed monocyte polarization and clustering of dendritic cells in patients with head and neck cancer: In vitro restoration of this immunosuppression by thymic hormones
    • Tas MP, Simons PJ, Balm FJ, Drexhage HA. Depressed monocyte polarization and clustering of dendritic cells in patients with head and neck cancer: in vitro restoration of this immunosuppression by thymic hormones. Cancer Immunol Immunother 1993;36:108-14
    • (1993) Cancer Immunol Immunother , vol.36 , pp. 108-114
    • Tas, M.P.1    Simons, P.J.2    Balm, F.J.3    Drexhage, H.A.4
  • 28
    • 0028886963 scopus 로고
    • In vivo effects of thymostimulin treatment on monocyte polarization, dendritic cell clustering and serum p15E-like trans-membrane factors in operable head and neck squamous cell carcinoma patients
    • Kerrebijn JD, Simons PJ, Tas M, Balm AJ, Drexhage HA. In vivo effects of thymostimulin treatment on monocyte polarization, dendritic cell clustering and serum p15E-like trans-membrane factors in operable head and neck squamous cell carcinoma patients. Eur Arch Otorhi- nolaryngol 1995;252:409-16
    • (1995) Eur Arch Otorhi- nolaryngol , vol.252 , pp. 409-416
    • Kerrebijn, J.D.1    Simons, P.J.2    Tas, M.3    Balm, A.J.4    Drexhage, H.A.5
  • 29
    • 0031974687 scopus 로고    scopus 로고
    • IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages
    • Allavena P, Piemonti L, Longoni D, Bernasconi S, Stoppacciaro A, Ruco L et al. IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur J Immunol 1998;28:359-69
    • (1998) Eur J Immunol , vol.28 , pp. 359-369
    • Allavena, P.1    Piemonti, L.2    Longoni, D.3    Bernasconi, S.4    Stoppacciaro, A.5    Ruco, L.6
  • 32
    • 0042202336 scopus 로고    scopus 로고
    • Immunosuppressive effects of soluble factors secreted by head and neck squamous cell carcinoma on dendritic cells and T lymphocytes
    • Kacani L, Wurm M, Schennach H, Braun I, Andrle J, Sprinzl GM. Immunosuppressive effects of soluble factors secreted by head and neck squamous cell carcinoma on dendritic cells and T lymphocytes. Oral Oncol 2003;39:672-9
    • (2003) Oral Oncol , vol.39 , pp. 672-679
    • Kacani, L.1    Wurm, M.2    Schennach, H.3    Braun, I.4    Andrle, J.5    Sprinzl, G.M.6
  • 33
    • 24044437159 scopus 로고    scopus 로고
    • Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): Possible link between angio- genesis and immune tolerance
    • Strauss L, Volland D, Kunkel M, Reichert TE. Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): possible link between angio- genesis and immune tolerance. Med Sci Monit 2005;11:BR280-92
    • (2005) Med Sci Monit , vol.11
    • Strauss, L.1    Volland, D.2    Kunkel, M.3    Reichert, T.E.4
  • 34
    • 0031777370 scopus 로고    scopus 로고
    • Peritumoral CD1a-positive dendritic cells are associated with improved survival in patients with tongue carcinoma
    • Goldman SA, Baker E, Weyant RJ, Clark MR, Myers JN, Lotze MT et al. Peritumoral CD1a-positive dendritic cells are associated with improved survival in patients with tongue carcinoma. Arch Otol Head Neck Surg 1998;124:641-6
    • (1998) Arch Otol Head Neck Surg , vol.124 , pp. 641-646
    • Goldman, S.A.1    Baker, E.2    Weyant, R.J.3    Clark, M.R.4    Myers, J.N.5    Lotze, M.T.6
  • 35
    • 0035464233 scopus 로고    scopus 로고
    • Increased levels of immune inhibitory CD34+ progenitor cells in the peripheral blood of patients with node positive head and neck squamous cell carcinomas and the ability of these CD34+ cells to differentiate into immune stimulatory dendritic cells
    • Lathers DM, Achille N, Kolesiak K, Hulett K, Sparano A, Petruzzelli GJ et al. Increased levels of immune inhibitory CD34+ progenitor cells in the peripheral blood of patients with node positive head and neck squamous cell carcinomas and the ability of these CD34+ cells to differentiate into immune stimulatory dendritic cells. Otolaryngol Head Neck Surg 2001;125:205-12
    • (2001) Otolaryngol Head Neck Surg , vol.125 , pp. 205-212
    • Lathers, D.M.1    Achille, N.2    Kolesiak, K.3    Hulett, K.4    Sparano, A.5    Petruzzelli, G.J.6
  • 36
    • 0037326299 scopus 로고    scopus 로고
    • Antitumor effect of secreted Flt3-ligand can act at distant tumour sites in a murine model of head and neck cancer
    • Dong J, Bohinski RJ, Li YQ, Van Waes C, Hendler F, Gleich L. Antitumor effect of secreted Flt3-ligand can act at distant tumour sites in a murine model of head and neck cancer. Cancer Gene Ther 2003;10:96-104
    • (2003) Cancer Gene Ther , vol.10 , pp. 96-104
    • Dong, J.1    Bohinski, R.J.2    Li, Y.Q.3    Van Waes, C.4    Hendler, F.5    Gleich, L.6
  • 37
    • 17644366838 scopus 로고    scopus 로고
    • Assessment of dendritic cell number and radiosensitivity in laryngeal tumours
    • Nix P, Stafford N, Cawkwell L, Greenman J. Assessment of dendritic cell number and radiosensitivity in laryngeal tumours. Clin Otolaryngol 2005;30:164-8
    • (2005) Clin Otolaryngol , vol.30 , pp. 164-168
    • Nix, P.1    Stafford, N.2    Cawkwell, L.3    Greenman, J.4
  • 38
    • 17744380809 scopus 로고    scopus 로고
    • Immunobiology of head and neck cancer
    • Whiteside TL. Immunobiology of head and neck cancer. Cancer Metastasis Rev 2005;24:95-105
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 95-105
    • Whiteside, T.L.1
  • 39
    • 0033776411 scopus 로고    scopus 로고
    • Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck: A phase 1 study
    • To WC, Wood BG, Krauss JC, Strome M, Esclamado RM, Lavertu P et al. Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck: a phase 1 study. Arch Otolaryngol Head Neck Surg 2000;126:1225-31
    • (2000) Arch Otolaryngol Head Neck Surg , vol.126 , pp. 1225-1231
    • To, W.C.1    Wood, B.G.2    Krauss, J.C.3    Strome, M.4    Esclamado, R.M.5    Lavertu, P.6
  • 40
    • 0037371233 scopus 로고    scopus 로고
    • Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer
    • Chang AE, Li Q, Jiang G, Teknos TN, Chepeha DB, Bradford CR. Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer. Head Neck 2003;25:198-209
    • (2003) Head Neck , vol.25 , pp. 198-209
    • Chang, A.E.1    Li, Q.2    Jiang, G.3    Teknos, T.N.4    Chepeha, D.B.5    Bradford, C.R.6
  • 41
    • 7444229927 scopus 로고    scopus 로고
    • Antitumor vaccination in patients with head and neck squamous cell carcinomas with autologous virus- modified tumor cells
    • Karcher J, Dyckhoff G, Beckhove P, Reisser C, Brysch M, Ziouta Y et al. Antitumor vaccination in patients with head and neck squamous cell carcinomas with autologous virus- modified tumor cells. Cancer Res 2004;64:8057-61
    • (2004) Cancer Res , vol.64 , pp. 8057-8061
    • Karcher, J.1    Dyckhoff, G.2    Beckhove, P.3    Reisser, C.4    Brysch, M.5    Ziouta, Y.6
  • 42
    • 16644393058 scopus 로고    scopus 로고
    • Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine
    • Herold-Mende C, Karcher J, Dyckhoff G, Schirrmacher V. Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine. Adv Otorhinolaryngol 2005;62:173-83
    • (2005) Adv Otorhinolaryngol , vol.62 , pp. 173-183
    • Herold-Mende, C.1    Karcher, J.2    Dyckhoff, G.3    Schirrmacher, V.4
  • 44
    • 2342627345 scopus 로고    scopus 로고
    • A dendritic cell based hybrid cell vaccine generated by electrofusion for immunotherapy strategies in HNSCC
    • Weise JB, Maune S, Gorogh T, Kabelitz D, Arnold N, Pfisterer J et al. A dendritic cell based hybrid cell vaccine generated by electrofusion for immunotherapy strategies in HNSCC. Auris Nasus Larynx 2004;31:149-53
    • (2004) Auris Nasus Larynx , vol.31 , pp. 149-153
    • Weise, J.B.1    Maune, S.2    Gorogh, T.3    Kabelitz, D.4    Arnold, N.5    Pfisterer, J.6
  • 45
    • 10644278651 scopus 로고    scopus 로고
    • Maturation of dendritic cells in the presence of living, apoptotic and necrotic tumour cells derived from squamous cell carcinoma of head and neck
    • Kacani L, Wurm M, Schwentner I, Andrle J, Schennach H, Sprinzl GM. Maturation of dendritic cells in the presence of living, apoptotic and necrotic tumour cells derived from squamous cell carcinoma of head and neck. Oral Oncol 2005;41:17-24
    • (2005) Oral Oncol , vol.41 , pp. 17-24
    • Kacani, L.1    Wurm, M.2    Schwentner, I.3    Andrle, J.4    Schennach, H.5    Sprinzl, G.M.6
  • 46
    • 33644692692 scopus 로고    scopus 로고
    • Cheah PL, Looi LM. p53: an overview of over two decades of study. Malays J Pathol 2001;23:9-16
    • Cheah PL, Looi LM. p53: an overview of over two decades of study. Malays J Pathol 2001;23:9-16
  • 47
    • 33645222458 scopus 로고    scopus 로고
    • The involvement of MAPK signaling pathways in determining the cellular response to p53 activation - cell cycle arrest or apoptosis
    • Brown L, Benchimol S. The involvement of MAPK signaling pathways in determining the cellular response to p53 activation - cell cycle arrest or apoptosis. J Biol Chem 2006;281:3832-40
    • (2006) J Biol Chem , vol.281 , pp. 3832-3840
    • Brown, L.1    Benchimol, S.2
  • 48
    • 0035136173 scopus 로고    scopus 로고
    • Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients
    • Nikitina EY, Clark JI, Van Beynen J, Chada S, Virmani AK, Carbone DP et al. Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients Clin Cancer Res 2001;7:127-35
    • (2001) Clin Cancer Res , vol.7 , pp. 127-135
    • Nikitina, E.Y.1    Clark, J.I.2    Van Beynen, J.3    Chada, S.4    Virmani, A.K.5    Carbone, D.P.6
  • 49
    • 0037096905 scopus 로고    scopus 로고
    • Frequencies of tetramer+ T cells specific for the wild-type sequence p53 (264-272) peptide in the circulation of patients with head and neck cancer
    • Hoffmann TK, Donnenberg AD, Finkelstein SD, Donnenberg VS, Friebe-Hoffmann U, Myers EN et al. Frequencies of tetramer+ T cells specific for the wild-type sequence p53 (264-272) peptide in the circulation of patients with head and neck cancer. Cancer Res 2002;62:3521-9
    • (2002) Cancer Res , vol.62 , pp. 3521-3529
    • Hoffmann, T.K.1    Donnenberg, A.D.2    Finkelstein, S.D.3    Donnenberg, V.S.4    Friebe-Hoffmann, U.5    Myers, E.N.6
  • 50
    • 0003951660 scopus 로고    scopus 로고
    • Generation of cytotoxic T cell responses to an HLA-A24 restricted epitope peptide derived from wild- type p53
    • Umano Y, Tsunoda T, Tanaka H, Matsuda K, Yamaue H, Tanimura H. Generation of cytotoxic T cell responses to an HLA-A24 restricted epitope peptide derived from wild- type p53. Br J Cancer 2001;84:1052-7
    • (2001) Br J Cancer , vol.84 , pp. 1052-1057
    • Umano, Y.1    Tsunoda, T.2    Tanaka, H.3    Matsuda, K.4    Yamaue, H.5    Tanimura, H.6
  • 51
    • 0032978854 scopus 로고    scopus 로고
    • Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells
    • Chikamatsu K, Nakano K, Storkus WJ, Appella E, Lotze MT, Whiteside TL et al. Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells. Clin Cancer Res 1999;5:1281-8
    • (1999) Clin Cancer Res , vol.5 , pp. 1281-1288
    • Chikamatsu, K.1    Nakano, K.2    Storkus, W.J.3    Appella, E.4    Lotze, M.T.5    Whiteside, T.L.6
  • 52
    • 0033798784 scopus 로고    scopus 로고
    • Induction of human cytotoxic T lymphocytes that preferentially recognise tumour cells bearing a conformational p53 mutant
    • McArdle SE, Rees RC, Mulcahy KA, Saba J, McIntyre CA, Murray AK. Induction of human cytotoxic T lymphocytes that preferentially recognise tumour cells bearing a conformational p53 mutant. Cancer Immunol Immunother 2000;49:417-25
    • (2000) Cancer Immunol Immunother , vol.49 , pp. 417-425
    • McArdle, S.E.1    Rees, R.C.2    Mulcahy, K.A.3    Saba, J.4    McIntyre, C.A.5    Murray, A.K.6
  • 54
    • 12944265535 scopus 로고    scopus 로고
    • A wild-type sequence p53 peptide presented by HLA-A24 induces cytotoxic T lymphocytes that recognize squamous cell carcinomas of the head and neck
    • Eura M, Chikamatsu K, Katsura F, Obata A, Sobao Y, Takiguchi M et al. A wild-type sequence p53 peptide presented by HLA-A24 induces cytotoxic T lymphocytes that recognize squamous cell carcinomas of the head and neck. Clin Cancer Res 2000;6:979-86
    • (2000) Clin Cancer Res , vol.6 , pp. 979-986
    • Eura, M.1    Chikamatsu, K.2    Katsura, F.3    Obata, A.4    Sobao, Y.5    Takiguchi, M.6
  • 55
    • 85044698885 scopus 로고    scopus 로고
    • In vitro generated cytolytic T lymphocytes reactive against head and neck cancer recognize multiple epitopes presented by HLA-A2, including pep- tides derived from the p53 and MDM-2 proteins
    • Asai T, Storkus WJ, Mueller-Berghaus J, Knapp W, DeLeo AB, Chikamatsu K et al. In vitro generated cytolytic T lymphocytes reactive against head and neck cancer recognize multiple epitopes presented by HLA-A2, including pep- tides derived from the p53 and MDM-2 proteins. Cancer Immun 2002;2:3
    • (2002) Cancer Immun , vol.2 , pp. 3
    • Asai, T.1    Storkus, W.J.2    Mueller-Berghaus, J.3    Knapp, W.4    DeLeo, A.B.5    Chikamatsu, K.6
  • 56
    • 33344457763 scopus 로고    scopus 로고
    • DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant
    • Bellier B, Dalba C, Clerc B, Desjardins D, Drury R, Cosset FL et al. DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant. Vaccine 2006;24:2643- 55
    • (2006) Vaccine , vol.24 , pp. 2643-2655
    • Bellier, B.1    Dalba, C.2    Clerc, B.3    Desjardins, D.4    Drury, R.5    Cosset, F.L.6
  • 57
    • 10744223658 scopus 로고    scopus 로고
    • Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe
    • Trimble C, Lin CT, Hung CF, Pai S, Juang J, He L et al. Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe. Vaccine 2003;21:4036-42
    • (2003) Vaccine , vol.21 , pp. 4036-4042
    • Trimble, C.1    Lin, C.T.2    Hung, C.F.3    Pai, S.4    Juang, J.5    He, L.6
  • 58
    • 12744263023 scopus 로고    scopus 로고
    • DNA vaccination against tumors
    • Prud'homme GJ. DNA vaccination against tumors. J Gene Med 2005;7:3-17
    • (2005) J Gene Med , vol.7 , pp. 3-17
    • Prud'homme, G.J.1
  • 59
    • 21844444548 scopus 로고    scopus 로고
    • Immune monitoring in a phase 1 trial of a PSA DNA vaccine in patients with hormone-refractory prostate cancer
    • Miller AM, Ozenci V, Kiessling R, Pisa P. Immune monitoring in a phase 1 trial of a PSA DNA vaccine in patients with hormone-refractory prostate cancer. J Immunother 2005;28:389-95
    • (2005) J Immunother , vol.28 , pp. 389-395
    • Miller, A.M.1    Ozenci, V.2    Kiessling, R.3    Pisa, P.4
  • 60
    • 67649284804 scopus 로고    scopus 로고
    • Vaccine Therapy With Immune Adjuvant in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma. http://www.clinicaltrials.gov/ct/ show/NCT 00085137 [Date last viewed, 06/03/2008]
    • Vaccine Therapy With Immune Adjuvant in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma. http://www.clinicaltrials.gov/ct/ show/NCT 00085137 [Date last viewed, 06/03/2008]
  • 61
    • 67649290909 scopus 로고    scopus 로고
    • Evaluation of the Immune Responses of GSK Biologicals' HPV Vaccine Following Manufacturing Process Adaptation. http://www.clinicaltrial.gov/ct/ show/NCT00250276 [Date last viewed, 06/03/2008]
    • Evaluation of the Immune Responses of GSK Biologicals' HPV Vaccine Following Manufacturing Process Adaptation. http://www.clinicaltrial.gov/ct/ show/NCT00250276 [Date last viewed, 06/03/2008]
  • 63
    • 67649266398 scopus 로고    scopus 로고
    • What is new in Head and Neck Cancer? http://www. cancerhelp.org.uk/trials [Date last viewed, 06/03/2008]
    • What is new in Head and Neck Cancer? http://www. cancerhelp.org.uk/trials [Date last viewed, 06/03/2008]
  • 64
    • 27544479318 scopus 로고    scopus 로고
    • Role of tyrosine kinase inhibitors in cancer therapy
    • Arora A, Scholar EM. Role of tyrosine kinase inhibitors in cancer therapy. J Pharmacol Exp Ther 2005; 315:971-9
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 971-979
    • Arora, A.1    Scholar, E.M.2
  • 65
    • 1542751704 scopus 로고    scopus 로고
    • Inhibiting tyrosine kinases: Successes and limitations
    • Arteaga CL. Inhibiting tyrosine kinases: successes and limitations. Cancer Biol Ther 2003;2:S79-83
    • (2003) Cancer Biol Ther , vol.2
    • Arteaga, C.L.1
  • 66
    • 2942603264 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors: Why does the current process of clinical development not apply to them?
    • Arteaga CL, Baselga J. Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them? Cancer Cell 2004;5:525-31
    • (2004) Cancer Cell , vol.5 , pp. 525-531
    • Arteaga, C.L.1    Baselga, J.2
  • 67
    • 14744278451 scopus 로고    scopus 로고
    • Combination nonviral interleukin-2 gene immunotheraphy for head and neck cancer: From bench top to bedside
    • O'Malley BW Jr, Li D, McQuone SJ, Ralston R. Combination nonviral interleukin-2 gene immunotheraphy for head and neck cancer: from bench top to bedside. Laryngoscope 2005;115:391-404
    • (2005) Laryngoscope , vol.115 , pp. 391-404
    • O'Malley Jr, B.W.1    Li, D.2    McQuone, S.J.3    Ralston, R.4
  • 68
    • 1942502672 scopus 로고    scopus 로고
    • Intratumoral administration of recombinant human interleukin 12 in head and neck squamous cell carcinoma patients elicits a T-helper 1 profile in the locoregional lymph nodes
    • van Herpen CM, Looman M, Zonneveld M, Scharenborg N, de Wilde PC, van de Locht L et al. Intratumoral administration of recombinant human interleukin 12 in head and neck squamous cell carcinoma patients elicits a T-helper 1 profile in the locoregional lymph nodes. Clin Cancer Res 2004;10:2626-35
    • (2004) Clin Cancer Res , vol.10 , pp. 2626-2635
    • van Herpen, C.M.1    Looman, M.2    Zonneveld, M.3    Scharenborg, N.4    de Wilde, P.C.5    van de Locht, L.6
  • 69
    • 20644463721 scopus 로고    scopus 로고
    • Neoadjuvant immunotherapy of oral squamous cell carcinoma modulates intratumoral CD4/ CD8 ratio and tumour microenvironment: A multicenter phase II clinical trial
    • Timar J, Ladanyi A, Forster-Horvath C, Lukits J, Dome B, Remenar E et al. Neoadjuvant immunotherapy of oral squamous cell carcinoma modulates intratumoral CD4/ CD8 ratio and tumour microenvironment: a multicenter phase II clinical trial. J Clin Oncol 2005;23:3421 -32
    • (2005) J Clin Oncol , vol.23 , pp. 3421-3432
    • Timar, J.1    Ladanyi, A.2    Forster-Horvath, C.3    Lukits, J.4    Dome, B.5    Remenar, E.6
  • 70
    • 0034760591 scopus 로고    scopus 로고
    • Combination nonviral interleukin 2 and interleukin 12 gene therapy for head and neck squamous cell carcinoma
    • Li D, Shugert E, Guo M, Bishop JS, O'Malley BW Jr. Combination nonviral interleukin 2 and interleukin 12 gene therapy for head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2001;127:1319-24
    • (2001) Arch Otolaryngol Head Neck Surg , vol.127 , pp. 1319-1324
    • Li, D.1    Shugert, E.2    Guo, M.3    Bishop, J.S.4    O'Malley Jr., B.W.5
  • 71
    • 67649293648 scopus 로고    scopus 로고
    • MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck. http://www.clinicaltrials. gov/ct/show/NCT00257738 [Date last viewed, 06/03/2008]
    • MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck. http://www.clinicaltrials. gov/ct/show/NCT00257738 [Date last viewed, 06/03/2008]
  • 72
    • 67649272591 scopus 로고    scopus 로고
    • A Phase 2 Clinical Trial of the Effectiveness of IRX-2 in Treating Patients With Operable Head and Neck Cancer. http://www.clinicaltrials.gov/ct/ show/NCT00210470 [Date last viewed, 06/03/2008]
    • A Phase 2 Clinical Trial of the Effectiveness of IRX-2 in Treating Patients With Operable Head and Neck Cancer. http://www.clinicaltrials.gov/ct/ show/NCT00210470 [Date last viewed, 06/03/2008]
  • 73
    • 10844290511 scopus 로고    scopus 로고
    • Phase I therapy study with (186)Re-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with head and neck squamous cell carcinoma
    • Borjesson PK, Postema EJ, Roos JC, Colnot DR, Marres HA, van Schie MH et al. Phase I therapy study with (186)Re-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with head and neck squamous cell carcinoma. Clin Cancer Res 2003;9:3961S-72S
    • (2003) Clin Cancer Res , vol.9
    • Borjesson, P.K.1    Postema, E.J.2    Roos, J.C.3    Colnot, D.R.4    Marres, H.A.5    van Schie, M.H.6
  • 74
    • 0034519646 scopus 로고    scopus 로고
    • Phase I therapy study of 186Re-labeled chimeric monoclonal antibody U36 in patients with squa- mous cell carcinoma of the head and neck
    • Colnot DR, Quak JJ, Roos JC, van Lingen A, Wilhelm AJ, van Kamp GJ et al. Phase I therapy study of 186Re-labeled chimeric monoclonal antibody U36 in patients with squa- mous cell carcinoma of the head and neck. J Nucl Med 2000;41:1999-2010
    • (2000) J Nucl Med , vol.41 , pp. 1999-2010
    • Colnot, D.R.1    Quak, J.J.2    Roos, J.C.3    van Lingen, A.4    Wilhelm, A.J.5    van Kamp, G.J.6
  • 75
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • Soulieres D, Senzer NN, Vokes EE, Hidalgo M, Agarwala SS, Siu LL. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 2004;22:77-85
    • (2004) J Clin Oncol , vol.22 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Vokes, E.E.3    Hidalgo, M.4    Agarwala, S.S.5    Siu, L.L.6


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