Peganine hydrochloride dihydrate an orally active antileishmanial agent

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 9, 2009, Pages 2585-2586

  Khaliq, Tanvir ^a   Misra, Pragya ^a   Gupta, Swati ^a   Reddy, K Papi ^a   Kant, Ruchir ^a   Maulik, P R ^a   Dube, Anuradha ^a   Narender, T ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Apoptosis; In vivo and in vitro antileishmanial activity; Peganinehydrochloridedihydrate; Topoisomerase inhibition

Indexed keywords

MILTEFOSINE; VASICINE;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOASSAY; DRUG DOSE COMPARISON; DRUG ISOLATION; FRACTIONATION; HAMSTER; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA DONOVANI; MACROPHAGE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEGANUM HARMALA; PLANT SEED; PROMASTIGOTE; VISCERAL LEISHMANIASIS; X RAY CRYSTALLOGRAPHY;

ADMINISTRATION, ORAL; ALKALOIDS; ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL ASSAY; CHEMISTRY, PHARMACEUTICAL; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; LEISHMANIA DONOVANI; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PEGANUM; PLANT EXTRACTS; QUINAZOLINES;

CRICETINAE; LEISHMANIA DONOVANI; MURINAE; PEGANUM HARMALA;

EID: 64249084534     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.039     Document Type: Article

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