Humanized mouse model of Cooley's anemia

Journal of Biological Chemistry

Volumn 284, Issue 8, 2009, Pages 4889-4896

  Huo, Yongliang ^a   McConnell, Sean C ^a   Liu, Shan Run ^a   Yang, Rui ^a   Zhang, Ting Ting ^a   Sun, Chiao Wang ^a   Wu, Li Chen ^a   Ryan, Thomas M ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABERRANT TRANSCRIPT; ADULT MICE; ANIMAL MODEL; CELL-BASED THERAPY; EMBRYONIC STEM CELLS; GENE REPLACEMENT; GLOBIN CHAINS; GLOBIN GENE; HUMAN CELLS; MOUSE MODELS; POLYPEPTIDE CHAIN; SPLICE DONORS;

BIOACTIVITY; GENE EXPRESSION;

HEMOGLOBIN;

BETA GLOBIN; GAMMA GLOBIN; POLYPEPTIDE; HEMOGLOBIN F;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANISOPOIKILOCYTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; EMBRYO; EMBRYONIC STEM CELL; ERYTHROCYTE DISORDER; FETUS; FETUS DEVELOPMENT; GENE CASSETTE; GENE EXPRESSION REGULATION; GENE INSERTION; GENE LOCUS; GENE SWITCHING; GENE TARGETING; GENETIC TRANSCRIPTION; GLOBIN SYNTHESIS; HOMOZYGOSITY; HUMAN; KNOCKOUT MOUSE; MICROCYTIC ANEMIA; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RNA SPLICING; THALASSEMIA MAJOR; ANIMAL; BETA THALASSEMIA; BIOSYNTHESIS; GENETICS; HETEROZYGOTE; HOMOZYGOTE; METABOLISM; QUANTITATIVE TRAIT LOCUS; TRANSGENIC MOUSE;

ANIMALIA; MURINAE; MUS;

ANIMALS; BETA-THALASSEMIA; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; FETAL HEMOGLOBIN; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MICE; MICE, TRANSGENIC; QUANTITATIVE TRAIT LOCI;

EID: 64149128896     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805681200     Document Type: Article

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