SERCA inhibition limits the functional effects of cyclic GMP in both control and hypertrophic cardiac myocytes

Pharmacology

Volumn 83, Issue 4, 2009, Pages 223-230

  Zhang, Qihang ^a   Davidov, Tomer ^a   Weiss, Harvey R ^a   Scholz, Peter M ^a,b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Calcium transients; Cardiac myocytes; Cyclic GMP; Cyclopiazonic acid; Myocyte function; Thapsigargin

Indexed keywords

8 BROMO CYCLIC GMP; CALCIUM; CYCLIC GMP; CYCLOPIAZONIC ACID; FURA 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; CYTOSOL; ENZYME INHIBITION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RENOVASCULAR HYPERTENSION;

ANIMALS; CALCIUM; CYCLIC GMP; HEART VENTRICLES; HYPERTENSION, RENAL; HYPERTROPHY; INDOLES; MYOCYTES, CARDIAC; RABBITS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN;

EID: 64149113453     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000205822     Document Type: Article

References (33)

1. Sperelakis N, Tohse N, Ohya Y, Masuda H: Cyclic GMP regulation of calcium slow channels in cardiac muscle and vascular smooth muscle cells. Adv Pharmacol 199; 26: 217-252.
2. 2+ current in rat ventricular myocytes. Circ Res 1995; 77: 803-812.
3. Su J, Zhang Q, Moalem J, Tse J, Scholz PM, Weiss HR: Functional effects of C-type natriuretic peptide and nitric oxide are attenuated in hypertrophic myocytes from pressure-overloaded mouse hearts. Am J Physiol Heart Circ Physiol 2005; 288:H1367-H1373.
4. Weiss HR, Gong GX, Straznicka M, Yan L, Tse J, Scholz PM: Cyclic GMP and cyclic AMP induced changes in control and hypertrophic cardiac myocyte function interact through cyclic GMP affected cyclic-AMP phosphodiesterases. Can J Physiol Pharmacol 1999; 77: 422-431.
5. Yan L, Zhang Q, Scholz PM, Weiss HR: Cyclic GMP protein kinase activity is reduced in thyroxine-induced hypertrophic cardiac myocytes. Clin Exp Pharmacol Physiol 2003; 30: 943-950.
6. Zhang Q, Lazar M, Molino B, Rodriguez R, Davidov T, Su J, Tse J, Weiss HR, Scholz PM: Reduction in interaction between cGMP and cAMP in dog ventricular myocytes with hy-pertrophic failure. Am J Physiol Heart Circ Physiol 2005; 289:H1251-H1257.
7. 2+ -ATPase in vascular endothelia l cells. Life Sci 2003; 73: 2019-2028.
8. 2+-ATPase. Pharmacology 2002; 64: 106-112.
9. 2+ current by a monoclonal antibody against the M 2 ACh receptor. Am J Physiol Cel l Physiol 2001; 281:C1251-C1258.
10. Vila-Petroff MG, Younes A, Egan J, Lakatta EG, Sollott SJ: Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes. Circ Res 1999; 84: 1020-1031.
11. Wollert KC, Fiedler B, Gambaryan S, Smo-lenski A, Heineke J, Butt E, Trautwein C, Lohmann SM, Drexler H: Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes. Hypertension 2002; 39: 87-92.
12. Hardt SE, Sadoshima J: Negative regulators of cardiac hypertrophy. Cardiovasc Res 2004; 63:500-509.
13. Vakili BA, Okin PM, Devereux RB: Prognostic implications of left ventricular hypertrophy. Am Heart J 2001; 141 : 334-341.
14. Nichols JR, Gonzalez NC: Increase in myocardial cell cGMP concentration in pressure-induced myocardial hypertrophy. J Mol Cell Cardiol 1982; 14:181-183.
15. Roitstein A, Kedem J, Cheinberg B, Weiss HR, Tse J, Scholz PM: The effect of intracoronary nitroprusside on cyclic GMP and regional mechanics is altered in a canine model of left ventricular hypertrophy. J Surg Res 1994; 57: 584-590.
16. Straznicka M, Gong G, Yan L, Scholz PM, Weiss HR: Cyclic GMP protein kinase mediates negative metabolic and functional effects of cyclic GMP in control and hypertrophied rabbit cardiac myocytes. J Cardiovasc Pharmacol 1999; 34: 229-236.
17. Engel S, Yan L, Weiss H, Scholz P: Negative functional effects of cGMP mediated by cGMP protein kinase are reduced in T4 cardiac myocytes. Eur J Pharmacol 2001; 421: 23-30.
18. Kuhn M: Molecular physiology of natriuretic peptide signalling. Basic Res Cardiol 2004; 99: 76-82.
19. Wollert KC, Drexler H: Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis. Heart Fail Rev 2002; 7:317-325.
20. Zhang Q, Scholz PM, He Y, Tse J, Weiss HR: Cyclic GMP signaling and regulation of SERCA activity during cardiac myocyte contraction. Cell Calcium 2005; 37:259-266.
21. Haddad GE, Sperelakis N, Bkaily G: Regulation of the calcium slow channel by cyclic GMP dependent protein kinase in chick heart cells. Mol Cell Biochem 1995; 148 : 89-94.
22. Shah AM, MacCarthy PA: Paracrine and au-tocrine effects of nitric oxide on myocardial function. Pharmacol Ther 2000; 86:49-86.
23. 2+ AT P a s e (SERCA) inhibition. J Bioenerg Biomembr 2005; 37: 365-368.
24. Hannan RD, Jenkins A, Jenkins AK, Brandenburger Y: Cardiac hypertrophy: a matter of translation. Clin Exp Pharmacol Physiol 2003; 30: 517-527.
25. Lorell BH, Carabello BA: Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 2000; 102:470-479.
26. Ritter O, Neyses L: The molecular basis of myocardial hypertrophy and heart failure. Trends Mol Med 2003; 9:313-321.
27. Babu GJ, Periasamy M: Transgenic mouse models for cardiac dysfunction by a specific gene manipulation. Methods Mol Med 2002; 112 : 365-377.
28. Campese VM, Krol E: Neurogenic factors in renal hypertension. Curr Hypertens Rep 2002; 4: 256-260.
29. Chen YH, Yet SE, Perrella MA: Role of heme oxygenase-1 in the regulation of blood pressure and cardiac function. Exp Biol Med 2003; 228:447-453.
30. Perrella MA, Yet SF: Role of heme oxygenase-1 in cardiovascular function. Curr Pharm Des 2003; 9:2479-2487.
31. Rabindranauth P, Naim KL, Scholz PM, Tse J, Sadoff JD, Weiss HR: Negative metabolic effects of cGMP are altered in renal hypertension induced cardiac hypertrophy. Basic Res Cardiol 1997; 92: 8-16.
32. 2 supply and consumption in early cardiac hypertrophy of renal hypertensive rabbits. Basic Res Cardiol 1989; 84: 13-21.
33. Dowell RT, Haithcoat JL, Thirkill HM, Palmer WK: Heart cyclic nucleotide responses to sustained aortic constriction in neonatal and adult rat. Am J Physiol 1984; 246:197-206.