Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation

Journal of Biological Chemistry

Volumn 284, Issue 8, 2009, Pages 5107-5118

  Endo, Makoto ^a   Antonyak, Marc A ^a   Cerione, Richard A ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DEVELOPMENT; CELL IDENTITY; CELL POLARITY; CELL-CELL ADHESION; CHEMICAL INHIBITORS; CONSTITUTIVELY ACTIVES; FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEINS; MICROTUBULE ASSOCIATED PROTEIN; MODEL SYSTEM; MTOR SIGNALING; NEURAL CELLS; NEURAL PROGENITOR CELLS; P19 CELLS; RETINOIC ACIDS; RNA INTERFERENCE; SIGNALING PATHWAYS; SIGNIFICANT IMPACTS; TERMINAL DIFFERENTIATION; UP-REGULATION;

ACIDS; ADHESION; ANTIBIOTICS; BIOACTIVITY; CELL ADHESION; CELL CULTURE; MAINTENANCE; NUCLEIC ACIDS; PIGMENTS; RNA; SIGNALING; TISSUE; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELL MEMBRANES;

FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 2; NOTCH RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN CDC42; RETINOIC ACID; TRANSCRIPTION FACTOR HES 5; TRANSCRIPTION FACTOR PAX6; ANTINEOPLASTIC AGENT; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CARRIER PROTEIN; ENZYME INHIBITOR; EYE PROTEIN; FRAP1 PROTEIN, MOUSE; HES5 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; PHOSPHOTRANSFERASE; POU5F1 PROTEIN, MOUSE; REPRESSOR PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GLIA CELL; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; ASTROCYTE; CELL ADHESION; CELL DIFFERENTIATION; CELL POLARITY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; NERVE CELL; PHYSIOLOGY; PRENATAL DEVELOPMENT; STEM CELL; TELENCEPHALON; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; ASTROCYTES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARRIER PROTEINS; CDC42 GTP-BINDING PROTEIN; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL POLARITY; ENZYME ACTIVATION; ENZYME INHIBITORS; EYE PROTEINS; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NEURONS; OCTAMER TRANSCRIPTION FACTOR-3; PAIRED BOX TRANSCRIPTION FACTORS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECEPTORS, NOTCH; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; STEM CELLS; TELENCEPHALON; TRETINOIN; UP-REGULATION;

EID: 64149107097     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807745200     Document Type: Article

References (44)

1. Gotz, M., and Huttner, W. B. (2005) Nat. Rev. Mol. Cell Biol. 6, 777-788
2. Kriegstein, A., Noctor, S., and Martinez-Cerdeno, V. (2006) Nat. Rev. Neurosci. 7, 883-890
3. Gotz, M., Stoykova, A., and Gruss, P. (1998) Neuron 21, 1031-1044
4. Kageyama, R., Ohtsuka, T., and Kobayashi, T. (2007) Development 134, 1243-1251
5. Hatakeyama, J., Bessho, Y., Katoh, K., Ookawara, S., Fujioka, M., Guillemot, F., and Kageyama, R. (2004) Development 131, 5539-5550
6. Quinn, J. C., Molinek, M., Martynoga, B. S., Zaki, P. A., Faedo, A., Bulfone, A., Hevner, R. F., West, J. D., and Price, D. J. (2007) Dev. Biol. 302, 50-65
7. Englund, C., Fink, A., Lau, C., Pham, D., Daza, R. A., Bulfone, A., Kowalczyk, T., and Hevner, R. F. (2005) J. Neurosci. 25, 247-251
8. Chen, L., Liao, G., Yang, L., Campbell, K., Nakafuku, M., Kuan, C. Y., and Zheng, Y. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 16520-16525
9. Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Brauninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, C., and Gotz, M. (2006) Nat. Neurosci. 9, 1099-1107
10. Heasman, S. J., and Ridley, A. J. (2008) Nat. Rev. Mol. Cell Biol. 9, 690-701
11. Wu, X., Li, S., Chrostek-Grashoff, A., Czuchra, A., Meyer, H., Yurchenco, P. D., and Brakebusch, C. (2007) Dev. Dyn. 236, 2767-2778
12. Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., Paus, R., Langbein, L., and Brakebusch, C. (2006) Genes Dev. 20, 571-585
13. Jaffe, A. B., and Hall, A. (2005) Annu. Rev. Cell Dev. Biol. 21, 247-269
14. Cerione, R. A. (2004) Trends Cell Biol. 14, 127-132
15. Etienne-Manneville, S., and Hall, A. (2002) Nature 420, 629-635
16. Takai, Y., Sasaki, T., and Matozaki, T. (2001) Physiol. Rev. 81, 153-208
17. Fang, Y., Park, I. H., Wu, A. L., Du, G., Huang, P., Frohman, M. A., Walker, S. J., Brown, H. A., and Chen, J. (2003) Curr. Biol. 13, 2037-2044
18. Chou, M. M., and Blenis, J. (1996) Cell 85, 573-583
19. Androutsellis-Theotokis, A., Leker, R. R., Soldner, F., Hoeppner, D. J., Ravin, R., Poser, S. W., Rueger, M. A., Bae, S. K., Kittappa, R., and McKay, R. D. (2006) Nature 442, 823-826
20. McBurney, M. W. (1993) Int. J. Dev. Biol. 37, 135-140
21. McBurney, M. W., Jones-Villeneuve, E. M., Edwards, M. K., and Anderson, P. J. (1982) Nature 299, 165-167
22. Bain, G., Ray, W. J., Yao, M., and Gottlieb, D. I. (1994) Bioessays 16, 343-348
23. Staines, W. A., Craig, J., Reuhl, K., and McBurney, M. W. (1996) Neuroscience 71, 845-853
24. Jones-Villeneuve, E. M., McBurney, M. W., Rogers, K. A., and Kalnins, V. I. (1982) J. Cell Biol. 94, 253-262
25. van der Heyden, M. A., and Defize, L. H. (2003) Cardiovasc. Res. 58, 292-302
26. Skerjanc, I. S. (1999) Trends Cardiovasc. Med. 9, 139-143
27. Tu, S., Wu, W. J., Wang, J., and Cerione, R. A. (2003) J. Biol. Chem. 278, 49293-49300
28. Hartfuss, E., Galli, R., Heins, N., and Gotz, M. (2001) Dev. Biol. 229, 15-30
29. Dono, R. (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. 284, R867-881
30. Yoon, K., and Gaiano, N. (2005) Nat. Neurosci. 8, 709-715
31. Ameerun, R. F., de Winter, J. P., van den Eijnden-van Raaij, A. J., den Hertog, J., de Laat, S. W., and Tertoolen, L. G. (1996) Cell Growth Differ. 7, 1679-1688
32. Wang, C., Xia, C., Bian, W., Liu, L., Lin, W., Chen, Y. G., Ang, S. L., and Jing, N. (2006) Mol. Biol. Cell 17, 3075-3084
33. Hiratochi, M., Nagase, H., Kuramochi, Y., Koh, C. S., Ohkawara, T., and Nakayama, K. (2007) Nucleic Acids Res. 35, 912-922
34. Ma, Q. H., Futagawa, T., Yang, W. L., Jiang, X. D., Zeng, L., Takeda, Y., Xu, R. X., Bagnard, D., Schachner, M., Furley, A. J., Karagogeos, D., Watanabe, K., Dawe, G. S., and Xiao, Z. C. (2008) Nat. Cell Biol. 10, 283-294
35. Wang, L., Li, S., and Jungalwala, F. B. (2007) J. Neurosci. Res. 86, 1254-1266
36. Reynolds, B. A., Tetzlaff, W., and Weiss, S. (1992) J. Neurosci. 12, 4565-4574
37. Wu, W. J., Tu, S., and Cerione, R. A. (2003) Cell 114, 715-725
38. Farah, M. H., Olson, J. M., Sucic, H. B., Hume, R. I., Tapscott, S. J., and Turner, D. L. (2000) Development 127, 693-702
39. Murray, R. C., Tapscott, S. J., Petersen, J. W., Calof, A. L. and McCormick, M. B. (2000) Dev. Dyn. 218, 189-194
40. Armour, C., Garson, K., and McBurney, M. W. (1999) Exp. Cell Res. 251, 79-91
41. McCormick, M. B., Tamimi, R. M., Snider, L., Asakura, A., Bergstrom, D., and Tapscott, S. J. (1996) Mol. Cell Biol. 16, 5792-5800
42. Skerjanc, I. S., Slack, R. S., and McBurney, M. W. (1994) Mol. Cell Biol. 14, 8451-8459
43. Okada, Y., Shimazaki, T., Sobue, G., and Okano, H. (2004) Dev. Biol. 275, 124-142
44. Chen, F., Ma, L., Parrini, M. C., Mao, X., Lopez, M., Wu, C., Marks, P. W., Davidson, L., Kwiatkowski, D. J., Kirchhausen, T., Orkin, S. H., Rosen, F. S., Mayer, B. J., Kirschner, M. W., and Alt, F. W. (2000) Curr. Biol. 10, 758-765