Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells

Blood

Volumn 111, Issue 7, 2008, Pages 3322-3330

  Ghiaur, Gabriel ^a   Ferkowicz, Michael J ^b   Milsom, Michael D ^a   Bailey, Jeff ^a   Witte, David ^a   Cancelas, Jose A ^a,c   Yoder, Mervin C ^b   Williams, David A ^a,d  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROPEPTIDE; RAC PROTEIN; RAC1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CELL ASSAY; CELL COUNT; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FETUS LIVER; GENE DELETION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; TRANSGENIC MOUSE; YOLK SAC; ANIMAL; ARTICLE; BONE MARROW; CELL MOTION; CYTOLOGY; EXTRAMEDULLARY HEMATOPOIESIS; FEMALE; GENETICS; LIVER; MALE; MESONEPHROS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT;

ANIMALS; BONE MARROW; CELL MOVEMENT; EMBRYONIC DEVELOPMENT; FEMALE; HEMATOPOIESIS, EXTRAMEDULLARY; HEMATOPOIETIC STEM CELLS; LIVER; MALE; MESONEPHROS; MICE; MICE, TRANSGENIC; NEUROPEPTIDES; RAC GTP-BINDING PROTEINS; YOLK SAC;

EID: 64049107119     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-09-078162     Document Type: Review

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