Inhibitory effects of sesquiterpene lactones isolated from Eupatorium chinense L. on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 8, 2009, Pages 3189-3197

  Itoh, Tomohiro ^a   Oyama, Masayoshi ^b   Takimoto, Norihiko ^b   Kato, Chihiro ^b   Nozawa, Yoshinori ^a   Akao, Yukihiro ^a   Iinuma, Munekazu ^b  

^a GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Allergy; degranulation; Eupatorium chinense L.; Rat basophilic leukemia RBL 2H3 cells; Sesquiterpene lactone

Indexed keywords

3 ACETOXY 8 SARRACENYLOXYHELIANGA 1(10),4,11(13) TRIEN 6,12 OLIDE; 3 HYDROXY 8 (2' METHYLBUTYROYLOXY) 14 OXOMELAMPA 1(10),4 DIEN 6,12 OLIDE; 3 HYDROXY 8 ACETOXYSARRACENYLOXYGERMACRA 1(10),4,11(13) TRIEN 6,12 OLIDE; 3 HYDROXY 8 SARRACENYLOXYGERMACRA 1(10),4,11(13) TRIEN 6,12 OLIDE; 3,14 DIHYDROXY 8 (2' METHYLBUTYROYLOXY)HELIANGA 1(10),4,11(13) TRIEN 6,12 OLIDE; CALCIUM ION; DEACETYLEUPASERRIN; EUPAFORMOSANIN; EUPALININ A; EUPALININ C; EUPATORIUM CHINENSE EXTRACT; FC RECEPTOR; IMMUNOGLOBULIN E; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE LYN; PROTEIN KINASE SYK; SESQUITERPENE LACTONE DERIVATIVE; SILVER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BASOPHIL DEGRANULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; EUPATORIUM; EUPATORIUM CHINENSE; MALE; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BASOPHIL DEGRANULATION TEST; BASOPHILS; CALCIUM; CELL DEGRANULATION; EUPATORIUM; HISTAMINE RELEASE; IMMUNOGLOBULIN E; LACTONES; LEUKEMIA, BASOPHILIC, ACUTE; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PASSIVE CUTANEOUS ANAPHYLAXIS; RATS; REACTIVE OXYGEN SPECIES; SESQUITERPENES; SIGNAL TRANSDUCTION;

EUPATORIUM CHINENSE; MUS; RATTUS;

EID: 64049106510     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.02.062     Document Type: Article

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