메뉴 건너뛰기




Volumn 382, Issue 3, 2009, Pages 614-619

βPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport

Author keywords

PIX; Breast cancer cells; GIT1; Hepatocyte growth factor; Lamellipodia; WAVE2

Indexed keywords

BETA PIX PROTEIN; GIT 1 PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN DERIVATIVE; RNA; SCATTER FACTOR; UNCLASSIFIED DRUG; WAVE2 PROTEIN; CELL CYCLE PROTEIN; GIT1 PROTEIN, HUMAN; HGF PROTEIN, HUMAN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SIGNAL TRANSDUCING ADAPTOR PROTEIN; WASF2 PROTEIN, HUMAN; WISKOTT ALDRICH SYNDROME PROTEIN;

EID: 64049088396     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.083     Document Type: Article
Times cited : (4)

References (26)
  • 1
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: a physically integrated molecular process
    • Lauffenburger D.A., and Horwitz A.F. Cell migration: a physically integrated molecular process. Cell 84 (1996) 359-369
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 2
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • Condeelis J., and Segall J.E. Intravital imaging of cell movement in tumours. Nat Rev. Cancer 3 (2003) 921-930
    • (2003) Nat Rev. Cancer , vol.3 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 3
    • 28444472417 scopus 로고    scopus 로고
    • The great escape: when cancer cells hijack the genes for chemotaxis and motility
    • Condeelis J., Singer R.H., and Segall J.E. The great escape: when cancer cells hijack the genes for chemotaxis and motility. Annu. Rev. Cell Dev. Biol. 21 (2005) 695-718
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 695-718
    • Condeelis, J.1    Singer, R.H.2    Segall, J.E.3
  • 4
    • 0025078512 scopus 로고
    • The cellular functions of small GTP-binding proteins
    • Hall A. The cellular functions of small GTP-binding proteins. Science 249 (1990) 635-640
    • (1990) Science , vol.249 , pp. 635-640
    • Hall, A.1
  • 6
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley A.J., Paterson H.F., Johnston C.L., Diekmann D., and Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70 (1992) 401-410
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 7
    • 0032403083 scopus 로고    scopus 로고
    • WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
    • Miki H., Suetsugu S., and Takenawa T. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 17 (1998) 6932-6941
    • (1998) EMBO J. , vol.17 , pp. 6932-6941
    • Miki, H.1    Suetsugu, S.2    Takenawa, T.3
  • 9
    • 0034619847 scopus 로고    scopus 로고
    • IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
    • Miki H., Yamaguchi H., Suetsugu S., and Takenawa T. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 408 (2000) 732-735
    • (2000) Nature , vol.408 , pp. 732-735
    • Miki, H.1    Yamaguchi, H.2    Suetsugu, S.3    Takenawa, T.4
  • 10
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Bishop A.L., and Hall A. Rho GTPases and their effector proteins. Biochem. J. 348 (2000) 241-255
    • (2000) Biochem. J. , vol.348 , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 11
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser E., Leung T., Salihuddin H., Zhao Z.S., and Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367 (1994) 40-46
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 12
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch G.M. Biology of the p21-activated kinases. Annu. Rev. Biochem. 72 (2003) 743-781
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 14
    • 0033843129 scopus 로고    scopus 로고
    • Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly
    • Zhao Z.S., Manser E., Loo T.H., and Lim L. Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly. Mol. Cell. Biol. 20 (2000) 6354-6363
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6354-6363
    • Zhao, Z.S.1    Manser, E.2    Loo, T.H.3    Lim, L.4
  • 15
    • 0034607876 scopus 로고    scopus 로고
    • GIT proteins, a novel family of phosphatidylinositol 3,4,5-trisphosphate-stimulated GTPase-activating proteins for ARF6
    • Vitale N., Patton W.A., Moss J., Vaughan M., Lefkowitz R.J., and Premont R.T. GIT proteins, a novel family of phosphatidylinositol 3,4,5-trisphosphate-stimulated GTPase-activating proteins for ARF6. J. Biol. Chem. 275 (2000) 13901-13906
    • (2000) J. Biol. Chem. , vol.275 , pp. 13901-13906
    • Vitale, N.1    Patton, W.A.2    Moss, J.3    Vaughan, M.4    Lefkowitz, R.J.5    Premont, R.T.6
  • 16
    • 33646705915 scopus 로고    scopus 로고
    • The multifunctional GIT family of proteins
    • Hoefen R.J., and Berk B.C. The multifunctional GIT family of proteins. J. Cell Sci. 119 (2006) 1469-1475
    • (2006) J. Cell Sci. , vol.119 , pp. 1469-1475
    • Hoefen, R.J.1    Berk, B.C.2
  • 17
    • 0035999990 scopus 로고    scopus 로고
    • Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway
    • Brown M.C., West K.A., and Turner C.E. Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway. Mol. Biol. Cell 13 (2002) 1550-1565
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1550-1565
    • Brown, M.C.1    West, K.A.2    Turner, C.E.3
  • 18
    • 16344390935 scopus 로고    scopus 로고
    • A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC
    • Zhang H., Webb D.J., Asmussen H., Niu S., and Horwitz A.F. A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J. Neurosci. 25 (2005) 3379-3388
    • (2005) J. Neurosci. , vol.25 , pp. 3379-3388
    • Zhang, H.1    Webb, D.J.2    Asmussen, H.3    Niu, S.4    Horwitz, A.F.5
  • 19
    • 0036537895 scopus 로고    scopus 로고
    • GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration
    • Manabe R., Kovalenko M., Webb D.J., and Horwitz A.R. GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. J. Cell Sci. 115 (2002) 1497-1510
    • (2002) J. Cell Sci. , vol.115 , pp. 1497-1510
    • Manabe, R.1    Kovalenko, M.2    Webb, D.J.3    Horwitz, A.R.4
  • 20
    • 45049085512 scopus 로고    scopus 로고
    • Requirement of kinesin-mediated membrane transport of WAVE2 along microtubules for lamellipodia formation promoted by hepatocyte growth factor
    • Takahashi K., and Suzuki K. Requirement of kinesin-mediated membrane transport of WAVE2 along microtubules for lamellipodia formation promoted by hepatocyte growth factor. Exp. Cell Res. 314 (2008) 2313-2322
    • (2008) Exp. Cell Res. , vol.314 , pp. 2313-2322
    • Takahashi, K.1    Suzuki, K.2
  • 21
    • 60549098791 scopus 로고    scopus 로고
    • Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex
    • Takahashi K., and Suzuki K. Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex. Cell. Signal. 21 (2009) 695-703
    • (2009) Cell. Signal. , vol.21 , pp. 695-703
    • Takahashi, K.1    Suzuki, K.2
  • 22
    • 41549102357 scopus 로고    scopus 로고
    • The PIX-GIT complex: a G protein signaling cassette in control of cell shape
    • Frank S.R., and Hansen S.H. The PIX-GIT complex: a G protein signaling cassette in control of cell shape. Semin. Cell Dev. Biol. 19 (2008) 234-244
    • (2008) Semin. Cell Dev. Biol. , vol.19 , pp. 234-244
    • Frank, S.R.1    Hansen, S.H.2
  • 23
    • 34547866453 scopus 로고    scopus 로고
    • Role of phospholipase Cγ1 in cell spreading requires association with a βPix/GIT1-containing complex, leading to activation of Cdc42 and Rac1
    • Jones N.P., and Katan M. Role of phospholipase Cγ1 in cell spreading requires association with a βPix/GIT1-containing complex, leading to activation of Cdc42 and Rac1. Mol. Cell. Biol. 27 (2007) 5790-5805
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 5790-5805
    • Jones, N.P.1    Katan, M.2
  • 24
    • 39549086119 scopus 로고    scopus 로고
    • Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells
    • Suzuki K., and Takahashi K. Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells. Biochem. Biophys. Res. Commun. 368 (2008) 199-204
    • (2008) Biochem. Biophys. Res. Commun. , vol.368 , pp. 199-204
    • Suzuki, K.1    Takahashi, K.2
  • 26
    • 0035833251 scopus 로고    scopus 로고
    • The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)
    • West K.A., Zhang H., Brown M.C., Nikolopoulos S.N., Riedy M.C., Horwitz A.F., and Turner C.E. The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J. Cell Biol. 154 (2001) 161-176
    • (2001) J. Cell Biol. , vol.154 , pp. 161-176
    • West, K.A.1    Zhang, H.2    Brown, M.C.3    Nikolopoulos, S.N.4    Riedy, M.C.5    Horwitz, A.F.6    Turner, C.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.