Malachite green induces cardiovascular defects in developing zebrafish (Danio rerio) embryos by blocking VEGFR-2 signaling

Biochemical and Biophysical Research Communications

Volumn 382, Issue 3, 2009, Pages 486-491

  Jang, Gun Hyuk ^a   Park, In Sook ^b   Lee, Sun Hee ^a   Huh, Tae Lin ^a   Lee, You Mie ^a  

^a Kyungpook National University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Cardiovascular defect; Malachite green; Toxicity; VEGFR2 phosphorylation; Zebrafish

Indexed keywords

MALACHITE GREEN; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR DISEASE; CELL DEATH; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; EMBRYO DEVELOPMENT; GROWTH RETARDATION; HEART DEVELOPMENT; HEART RATE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; ZEBRA FISH;

ANIMALS; APOPTOSIS; BRADYCARDIA; CARDIOVASCULAR ABNORMALITIES; CELLS, CULTURED; COLORING AGENTS; EMBRYO, NONMAMMALIAN; ENDOTHELIUM, VASCULAR; FUNGICIDES, INDUSTRIAL; HEMATOPOIESIS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; ROSANILINE DYES; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; ZEBRAFISH;

DANIO RERIO; MAMMALIA; VERTEBRATA;

EID: 64049084629     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.01.118     Document Type: Article

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