Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure

Kidney International

Volumn 75, Issue 8, 2009, Pages 800-808

  Siedlecki, Andrew M ^a,b   Jin, Xiaohua ^a   Muslin, Anthony J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

Blood pressure; Rapamycin; Uremia; Ventricular hypertrophy

Indexed keywords

ATRIAL NATRIURETIC FACTOR; HYDRALAZINE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN HEAVY CHAIN BETA; NITROGEN; PROTEIN KINASE B; PROTEIN KINASE B BETA; RAPAMYCIN; S6 KINASE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BODY MASS; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPERIMENTAL MODEL; GENE EXPRESSION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART WEIGHT; MALE; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSTHORACIC ECHOCARDIOGRAPHY; UREA NITROGEN BLOOD LEVEL; UREMIA;

ANIMALS; BLOOD PRESSURE; CARDIOMEGALY; CARDIOMYOPATHY, HYPERTROPHIC; CARRIER PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYDRALAZINE; MICE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS;

EID: 63949083046     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.690     Document Type: Article

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