One-pot three-step synthesis of pyrazinothienopyrimidines using tandem aza-wittig/electrocyclic ring closure

Synthesis

Volumn , Issue 3, 2009, Pages 438-444

  Blanco, Gerardo ^a   Fernández Mato, Antonio ^a   Quintela, José M ^a   Peinador, Carlos ^a  

^a UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

Cyclizations; Electrocyclic reactions; Heterocycles; Phosphazenes; Wittig reaction

Indexed keywords

CYCLIZATIONS; ELECTROCYCLIC REACTIONS; HETEROCYCLES; PHOSPHAZENES; WITTIG REACTION;

ALDEHYDES; AMINES; CYCLIZATION;

AMINATION;

2 BUTYLIMINO 3 PHENYL 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 2 ISOPROPYLIMINO 3 PHENYL 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 2 OXO 3 PHENYL 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 (4 METHYLPHENYL) 2 OXO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 (4 NITROPHENYL) 2 OXO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 (BUTYL) 2 (4 NITROPHENYL)IMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 (4 METHYLPHENYL)IMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 BUTYLIMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 ISOPROPYLIMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 OXO PYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 PHENYLIMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 BUTYL 2 THIOXO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 ISOPROPYL 2 OXO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 PHENYL 2 (4 METHYLPHENYL)IMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 PHENYL 2 (4 NITROPHENYL)IMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3 PHENYL 2 PHENYLIMINO 2,3 DIHYDROPYRAZINO[2',3':4,5]THIENO[3,2 D]PYRIMIDINE; 3-AMINO-2-FORMYLTHIENO[2,3-B]PYRAZINE; ALKENE DERIVATIVE; AMINE; DICHLOROTRIPHENYLPHOSPHINE; HETEROCUMULENE DERIVATIVE; ISOCYANIC ACID DERIVATIVE; PHOSPHINE DERIVATIVE; PYRAZINE DERIVATIVE; PYRAZINOTHIENOPYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; CONFERENCE PAPER; CRYSTAL STRUCTURE; CYCLIZATION; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION; WITTIG REACTION; X RAY CRYSTALLOGRAPHY;

EID: 63849332480     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0028-1083318     Document Type: Conference Paper

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