Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers

Journal of Animal Science

Volumn 87, Issue 4, 2009, Pages 1394-1406

  Hilton, G G ^a   Montgomery, J L ^b   Krehbiel, C R ^a   Yates, D A ^b   Hutcheson, J P ^a   Nichols, W T ^a   Streeter, M N ^a   Blanton Jr , J R ^a   Miller, M F ^c  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b MERCK ANIMAL HEALTH   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

adrenergic agonist; Beef cattle; Carcasses cut ability; Tenderness; Yield; Zilpaterol hydrochloride

Indexed keywords

CALCIUM BINDING PROTEIN; CALPAIN; CALPASTATIN; MONENSIN; TRIMETHYLSILYL DERIVATIVE; TYLOSIN; ZILPATEROL;

ANIMAL; ARTICLE; BODY COMPOSITION; CATTLE; CHEMISTRY; DEMOGRAPHY; DIET SUPPLEMENTATION; HUMAN; MALE; MEAT; METABOLISM; PH; PHYSIOLOGY; RANDOMIZATION; SENSATION; SHEAR STRENGTH; SKELETAL MUSCLE; STANDARD;

ANIMALS; BODY COMPOSITION; CALCIUM-BINDING PROTEINS; CALPAIN; CATTLE; DEMOGRAPHY; DIETARY SUPPLEMENTS; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MEAT; MONENSIN; MUSCLE, SKELETAL; RANDOM ALLOCATION; SENSATION; SHEAR STRENGTH; TRIMETHYLSILYL COMPOUNDS; TYLOSIN;

BOS;

EID: 63849193726     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2008-1170     Document Type: Article

References (52)

1. AMSA. 1991. Guidelines for meat color evaluation. Proc. 44 Recip. Meat Conf. Natl. Live Stock and Meat Board, Chicago, IL.
2. AMSA. 1995. Research Guidelines for Cookery, Sensory Evaluation and Instrumental Tenderness of Fresh Meat. Natl. Live Stock and Meat Board, Chicago, IL.
3. Anderson, D. B., E. L. Veenhuizen, J. F. Wagner, M. I. Wray, and D. H. Mowrey. 1989. The effect of ractopamine hydrochloride on nitrogen retention, growth performance and carcass composition of beef cattle. J. Anim. Sci. 67(Suppl. 1):222. (Abstr.)
4. AOAC. 1990. Official Methods of Analysis. 15th ed. Assoc. Off. Anal. Chem., Arlington, VA.
5. Avendaño-Reyes, L., V. Torres-Rodríguez, F. J. Meraz-Murillo, C. Pérez-Linares, F. Figueroa-Saavedra, and P. H. Robinson. 2006. Effect of two β-adrenergic agonists on finishing performance, carcass characteristics, and meat quality of feedlot steers. J. Anim. Sci. 84:3259-3265.
6. Bardsley, R. G., S. M. J. Allcock, J. M. Dawson, N. W. Dumelow, J. A. Higgins, Y. V. Lasslett, A. K. Lockley, T. Parr, and P. J. Buttery. 1992. Effect of β-agonists on expression of calpain and calpastatin activity in skeletal muscle. Biochimie 74:267-273.
7. Berge, Ph., J. Culioli, A. Ouali, and M. F. Parat. 1993. Performance, muscle composition and meat texture in veal calves administered a beta-agonist (clenbuterol). Meat Sci. 33:191-206.
8. Boucqué, Ch. V., L. O. Fiems, R. J. Moermans, B. G. Cottyn, and M. Sommer. 1994. Effect of cimaterol on growth, carcass characteristics and meat quality in double-muscled Belgian Whiteblue bulls. Can. J. Anim. Sci. 74:707-709.
9. Casey, N. H., E. C. Webb, and J. L. Martin. 1997. Effects of zilpaterol and its withdrawal on carcass and meat quality of young steers. Pages 264-265 in Proc. 43rd Int. Congr. Meat Sci. Technol., Auckland, New Zealand.
10. Chikhou, F. H., A. P. Molooney, P. Allen, R. L. Joseph, P. V. Tarrant, J. F. Quirke, F. H. Austin, and J. F. Roche. 1993. Longterm effects of cimaterol in Friesian steers: II. Carcass composition and meat quality. J. Anim. Sci. 71:914-922.
11. Cross, H. R., R. Moen, and M. S. Stanfield. 1978. Training and testing of judges for sensory analysis of meat quality. Food Technol. 32:48-54.
12. Depenbusch, B. E., J. S. Drouillard, E. R. Loe, J. J. Higgins, M. E. Corrigan, and M. J. Quinn. 2008. Efficacy of monensin and tylosin in finishing diets based on steam-flaked corn with and without corn wet distillers grains with solubles. J. Anim. Sci. 86:2270-2276.
13. FASS. 1999. Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching. 1st rev. ed. Fed. Anim. Sci. Soc, Savoy, IL.
14. FDA. 2006. Freedom of information summary. Original new animal drug application NADA 141-258. Zilmax (zilpaterol hydrochloride) Type A medicated article for cattle fed in confinement for slaughter. http://www.fda.gov/cvm/FOI/ 141-258o08102006. pdf Accessed Apr. 26, 2007.
15. Fiems, L. O., Ch. V. Boucqué, and B. G. Cottyn. 1993. Effect of duration of a β-agonist treatment on growth, feed intake and carcass characteristics in finishing bulls. Arch. Anim. Nutr. 45:101-109.
16. Fiems, L. O., Ch. V. Boucqué, D. L. de Barbander, and B. G. Cottyn. 1995. The effect of the β-adrenergic agonist cimaterol on performance and carcass and meat quality in culled dairy cows. Anim. Sci. 61:19-23.
17. Fiems, L. O., B. Buts, Ch. V. Boucqué, D. I. Demeyer, and B. G. Cottyn. 1990. Effect of a β-agonist on meat quality and myofibrillar protein fragmentation in bulls. Meat Sci. 27:29-39.
18. Geesink, G. H., F. J. M. Smulders, H. L. J. M. Van Laack, J. H. Van der Kolk, Th. Wensing, and H. J. Breukink. 1993. Effects on meat quality of the use of clenbuterol in veal calves. J. Anim. Sci. 71:1161-1170.
19. Goodrich, R. D., J. E. Garrett, D. R. Gast, M. A. Kirick, D. A. Larson, and J. C. Meiske. 1984. Influence of monensin on the performance of cattle. J. Anim. Sci. 58:1484-1498.
20. Hankins, O. G., and P. E. Howe. 1946. Estimations of the composition of beef carcasses and cuts. USDA Tech. Bull. 926. USDA, Washington, DC.
21. 2+-dependent protease activities by hydrophobic and ion-exchange chromatography. J. Anim. Sci. 68:659-665.
22. 644,969 on muscle growth, endogenous proteinase activities, and postmortem proteolysis in wether lambs. J. Anim. Sci. 69:4823-4835.
23. Kretchmar, D. H., M. R. Hathaway, R. J. Epley, and W. R. Dayton. 1990. Alterations in postmortem degradation of myofibrillar proteins in muscle of lambs fed a β-adrenergic agonist. J. Anim. Sci. 68:1760-1772.
24. Krzywicki, K. 1979. Assessment of relative content of myoglobin, oxymyoglobin, and metmyoglobin at the surface of beef. Meat Sci. 3:1-10.
25. Leheska, J. M., J. L. Montgomery, C. R. Krehbiel, J. Cranston, D. A. Yates, J. P. Hutcheson, W. T. Nichols, M. Streeter, J. R. Blanton Jr., and M. F. Miller. 2008. Dietary zilpaterol hydrochloride. II. Carcass composition and meat palatability of beef cattle-Clinical trials. J. Anim. Sci. 87:1384-1393.
26. Luño, M., J. A. Beltrán, I. Jaime, and P. Roncalés. 1999. Textural assessment of clenbuterol treatment in beef. Meat Sci. 51:297- 303.
27. Mersmann, H. J. 1998. Overview of the effects of β-adrenergic receptor agonists on animal growth including mechanisms of action. J. Anim. Sci. 76:160-172.
28. Miller, M. F., M. A. Carr, C. B. Ramsey, K. L. Crockett, and L, C. Hoover. 2001. Consumer thresholds for establishing the value of beef tenderness. J. Anim. Sci. 79:3062-3068.
29. Miller, M. F., D. K. Garcia, M. E. Coleman, P. A. Ekeren, D. K. Lunt, K. A. Wagner, M. Procknor, T. H. Welsh Jr., and S. B. Smith. 1988. Adipose tissue, longissimus muscle and anterior pituitary growth and function in clenbuterol-fed heifers. J. Anim. Sci. 66:12-20.
30. Moloney, A. P., P. Allen, R. L. Joseph, P. V. Tarrant, and E. M. Convey. 1994. Carcass and meat quality of finishing Friesian steers the β-adrenergic agonist L-644,969. Meat Sci. 38:419-432.
31. Moloney, A. P., P. Allen, D. B. Ross, G. Olson, and E. M. Convey. 1990. Growth, feed efficiency and carcass composition of finishing Friesian steers fed the β-adrenergic agonist L-644,969. J. Anim. Sci. 68:1269-1277.
32. Montgomery, J. L., C. R. Krehbiel, J. Cranston, D. A. Yates, J. P. Hutcheson, W. T. Nichols, M. N. Streeter, D. T. Bechtol, E. Johnson, T. N. TerHune, and T. H. Montgomery. 2009a. Dietary zilpaterol hydrochloride. I. Feedlot performance and carcass traits of steers and heifers. J. Anim. Sci. 87:1374-1383.
33. Montgomery, J. L., C. R. Krehbiel, J. Cranston, D. A. Yates, J. P. Hutcheson, W. T. Nichols, M. N. Streeter, R. S. Swingle, and T. H. Montgomery. 2009b. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. J. Anim. Sci. 87:1013-1023.
34. 3 on beef quality in commercial heifers. Pages 725-729 in Revista, Científica, Facultad de Ciencias Veterinarias. Universidad del Zulia. 12.
35. NAMP. 1997. Meat Buyers Guide. Natl. Assoc. Meat Purveyors, Reston, VA.
36. Plascencia, A., N. Torrentera, and R. A. Zinn. 1999. Influence of the β-agonist, zilpaterol, on growth performance and carcass characteristics of feedlot steers. Proc. Western Sect. Am. Soc. Anim. Sci. 50:331-334.
37. Pringle, T. D., C. R. Calkins, M. Koohmaraie, and S. J. Jones. 1993. Effects over time of feeding a β-adrenergic agonist to wether lambs on animal performance, muscle growth, endogenous muscle proteinase activities, and meat tenderness. J. Anim. Sci. 71:636-644.
38. Quirke, J. F., P. Allen, A. P. Moloney, M. Sommer, J. P. Hanrahan, W. Sheehan, and J. F. Roche. 1988. Effect of the beta-agonist cimaterol on blood meta,bolite and hormone concentrations, growth and carcass composition in finishing Friesian steers. J. Anim. Physiol. Anim. Nutr. (Berl.) 60:128-136.
39. Ricks, C. A., R. H. Dalrymple, P. K. Baker, and D. L. Ingle. 1984. Use of a β-agonist to alter fat and muscle deposition in steers. J. Anim. Sci. 59:1247-1255.
40. Schiavetta, A. M., M. F. Miller, D. K. Lunt, S. K. Davis, and S. B. Smith. 1990. Adipose tissue cellularity and muscle growth in young steers fed the β-adrenergic agonist clenbuterol for 50 days and after 78 days of withdrawal. J. Anim. Sci. 68:3614- 3623.
41. Schroeder, A. L., D. M. Polser, S. B. Laudert, and G. J. Vogel. 2003. Effect of Optaflexx on sensory properties of beef. Optaflexx Exchange No. 3. Elanco Animal Health, Greenfield, IN.
42. Shackelford, S. D., J. B. Morgan, H. R. Cross, and J. W. Savell. 1991. Identification of threshold levels for Warner-Bratzler shear force in beef top loin steaks. J. Muscle Foods 2:289-296.
43. Shackelford, S. D., T. L. Wheeler, and M. Koohmaraie. 1997. Tenderness classification of beef: I. Evaluation of beef longissimus shear force at 1 or 2 days postmortem as a, predictor of aged beef tenderness. J. Anim. Sci. 75:2417-2422.
44. Snedecor, G. W., and W. G. Cochran. 1973. Statistical Methods. 6th ed. Iowa State Univ. Press, Ames.
45. Steel, R. G. D., and J. H. Torrie. 1980. Principles and Procedures of Statistics: A Biometrical Approach. 2nd ed. McGraw-Hill Book Co., New York, NY.
46. Strydom, P. E., E. M. Buys, and H. F. Strydom. 2000. The effect a beta-agonist (zilpaterol) on meat colour shelf life. Proc. 46th Int. Congr. Meat Sci. Technol., Buenos Aires, Argentina.
47. Strydom, P. E., and E. Nel. 1999. The effect of supplementation period of a beta-agonist (zilpaterol), electrical stimulation and ageing period on meat quality characteristics. Pages 474-475 in Proc. 46th Int. Congr. Meat Sci. Technol., Yokohama, Japan.
48. Strydom, P. E., E. H. Osier, E. Nel, and K.-.I. Leeuw. 1998. The effect of supplementation period of a beta-agonist (zilpaterol) on growth performance, carcass yield and meat quality characteristics. Pages 894-895 in Proc. 44th Int. Congr. Meat Sci. Technol., Barcelona, Spain.
49. USDA. 1996. Institutional Meat Purchase Specifications for Fresh Beef Products. Agric. Marketing Serv., USDA, Washington, DC.
50. USDA. 1997. Official United States Standards for Grades of Carcass Beef. Agric. Marketing Serv., USDA, Washington, DC.
51. Vestergaard, M., K. Sejrsen, and S. Klastrup. 1994. Growth, composition and eating quality of Longissimus dorsi from young bulls fed the beta-agonist cimaterol at consecutive developmental stages. Meat Sci. 38:55-66.
52. 644,969 on muscle protein turnover, endogenous proteinase activities, and meat tenderness in steers. J. Anim. Sci. 70:3035-3043.