The first synthesis of allyl isonitriles from baylis-hillman adducts, and their application in the synthesis of substituted imidazo[1,2-a]pyridines and tetraazadibenzoazulenes

Synthesis

Volumn , Issue 3, 2009, Pages 431-437

  Nayak, Maloy ^a   Kanojiya, Sanjeev ^a   Batra, Sanjay ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Allylamines; Baylis Hillman; Imidazo 1,2 a pyridines; Isonitriles; Multicompo Nent reactions

Indexed keywords

ALLYLAMINES; BAYLIS-HILLMAN; IMIDAZO[1,2-A]PYRIDINES; ISONITRILES; MULTICOMPO- NENT REACTIONS;

AMMONIUM COMPOUNDS; CHLORINE COMPOUNDS; STEREOCHEMISTRY; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL);

PYRIDINE;

2 (((2 (2 CHLORO 5 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (2 CHLOROPHENYL)PROP 2 ENENITRILE; 2 (((2 (2 CHLORO 5 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (4 METHYLPHENYL)PROP 2 ENENITRILE; 2 (((2 (2 CHLORO 5 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 PHENYLPROP 2 ENENITRILE; 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2-A]PYRIDIN 3 YL)AMINO)METHYL) 3 PHENYLPROP 2 ENENITRILE; 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (2,4 DICHLOROPHENYL)PROP 2 ENENITRILE; 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (4 FLUOROPHENYL)PROP 2 ENENITRILE; 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (4 METHOXYPHENYL)PROP 2 ENENITRILE; 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 (4 METHYLPHENYL)PROP 2 ENENITRILE; 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL) 3 PHENYLPROP 2 ENENITRILE; 2 (ISOCYANOMETHYL) 3 (4 METHOXYPHENYL)PROP 2 ENENITRILE; 2 (ISOCYANOMETHYL) 3 (4 METHYLPHENYL)PROP 2 ENENITRILE; 2 (ISOCYANOMETHYL) 3 PHENYLPROP 2 ENENITRILE; 3 (2 CHLOROPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2-A]PYRIDIN 3 YL)AMINO}METHYL)PROP 2 ENENITRILE; 3 (2 CHLOROPHENYL) 2 (((2 (4 CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (2 CHLOROPHENYL) 2 (ISOCYANOMETHYL)PROP 2 ENENITRILE; 3 (2,4 DICHLOROPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (2,4 DICHLOROPHENYL) 2 (ISOCYANOMETHYL)PROP 2 ENENITRILE; 3 (4 CHLOROPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (4 CHLOROPHENYL) 2 (((2 (4-CHLOROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (4 CHLOROPHENYL) 2 (ISOCYANOMETHYL)PROP 2 ENENITRILE; 3 (4 FLUOROPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (4 FLUOROPHENYL) 2 (ISOCYANOMETHYL)PROP 2 ENENITRILE; 3 (4 METHOXYPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; 3 (4 METHYLPHENYL) 2 (((2 (2 NITROPHENYL)IMIDAZO[1,2 A]PYRIDIN 3 YL)AMINO)METHYL)PROP 2 ENENITRILE; ALLYLISONITRILE DERIVATIVE; AMMONIUM CHLORIDE; AZULENE DERIVATIVE; IMIDAZO[1,2 A]PYRIDINE DERIVATIVE; NITRILE; TETRAAZADIBENZOAZULENE DERIVATIVE; UNCLASSIFIED DRUG;

BAYLIS HILLMAN REACTION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CONFERENCE PAPER; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

EID: 63849140419     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0028-1083306     Document Type: Conference Paper

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