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Volumn 150, Issue 4, 2009, Pages 1757-1765

Stressor and glucocorticoid-dependent induction of the immediate early gene krüppel-like factor 9: implications for neural development and plasticity

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 9; MESSENGER RNA; MIFEPRISTONE; SPIRONOLACTONE; UNCLASSIFIED DRUG;

EID: 63849102885     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1441     Document Type: Article
Times cited : (85)

References (53)
  • 1
    • 23444434948 scopus 로고    scopus 로고
    • Repeated stress and structural plasticity in the brain
    • Radley JJ, Morrison JH 2005 Repeated stress and structural plasticity in the brain. Ageing Res Rev 4:271-287
    • (2005) Ageing Res Rev , vol.4 , pp. 271-287
    • Radley, J.J.1    Morrison, J.H.2
  • 2
    • 34447103169 scopus 로고    scopus 로고
    • Chronic stress: Implications for neuronal morphology, function and neurogenesis
    • Joels M, Karst H, Krugers HJ, Lucassen PJ 2007 Chronic stress: implications for neuronal morphology, function and neurogenesis. Front Neuroendocrinol 28:72-96
    • (2007) Front Neuroendocrinol , vol.28 , pp. 72-96
    • Joels, M.1    Karst, H.2    Krugers, H.J.3    Lucassen, P.J.4
  • 3
    • 34447629382 scopus 로고    scopus 로고
    • Physiology and neurobiology of stress and adaptation: Central role of the brain
    • McEwen BS 2007 Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 87:873-904
    • (2007) Physiol Rev , vol.87 , pp. 873-904
    • McEwen, B.S.1
  • 4
    • 33745979170 scopus 로고    scopus 로고
    • Differential effects of prenatal stress on the morphological maturation of hippocampal neurons
    • Fujioka A, Fujioka T, Ishida Y, Maekawa T, Nakamura S 2006 Differential effects of prenatal stress on the morphological maturation of hippocampal neurons. Neuroscience 141:907-915
    • (2006) Neuroscience , vol.141 , pp. 907-915
    • Fujioka, A.1    Fujioka, T.2    Ishida, Y.3    Maekawa, T.4    Nakamura, S.5
  • 5
    • 32544448533 scopus 로고    scopus 로고
    • Stressful experience and learning across the lifespan
    • Shors TJ 2006 Stressful experience and learning across the lifespan. Annu Rev Psychol 57:55-85
    • (2006) Annu Rev Psychol , vol.57 , pp. 55-85
    • Shors, T.J.1
  • 6
    • 33646246383 scopus 로고    scopus 로고
    • Corticosteroid effects in the brain: U-shape it
    • Joels M 2006 Corticosteroid effects in the brain: U-shape it. Trends Pharmacol Sci 27:244-250
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 244-250
    • Joels, M.1
  • 7
    • 63849294495 scopus 로고    scopus 로고
    • Structural and functional evolution of vertebrate neuroendocrine stress systems
    • in press
    • Denver RJ, Structural and functional evolution of vertebrate neuroendocrine stress systems. Ann NY Acad Sci, in press
    • Ann NY Acad Sci
    • Denver, R.J.1
  • 8
    • 0033668897 scopus 로고    scopus 로고
    • Nongenomic membrane actions of glucocorticoids in vertebrates
    • Borski RJ 2000 Nongenomic membrane actions of glucocorticoids in vertebrates. Trends Endocrinol Metab 11:427-436
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 427-436
    • Borski, R.J.1
  • 9
    • 0345874610 scopus 로고    scopus 로고
    • Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model
    • Norman AW, Mizwicki MT, Norman DP 2004 Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model. Nat Rev Drug Discov 3:27-41
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 27-41
    • Norman, A.W.1    Mizwicki, M.T.2    Norman, D.P.3
  • 10
    • 33751543436 scopus 로고    scopus 로고
    • Minireview: Rapid glucocorticoid signaling via membrane-associated receptors
    • Tasker JG, Di S, Malcher-Lopes R 2006 Minireview: rapid glucocorticoid signaling via membrane-associated receptors. Endocrinology 147:5549-5556
    • (2006) Endocrinology , vol.147 , pp. 5549-5556
    • Tasker1    JG, D.S.2    Malcher-Lopes, R.3
  • 11
    • 0037218919 scopus 로고    scopus 로고
    • Sp1- and Krüppel-like transcription factors
    • Kaczynski J, Cook T, Urrutia R 2003 Sp1- and Krüppel-like transcription factors. Genome Biol 4:206
    • (2003) Genome Biol , vol.4 , pp. 206
    • Kaczynski, J.1    Cook, T.2    Urrutia, R.3
  • 12
    • 16244405603 scopus 로고    scopus 로고
    • Mammalian SP/KLF transcription factors: Bring in the family
    • Guntram S, Bruford E, Philipsen S 2005 Mammalian SP/KLF transcription factors: bring in the family. Genomics 85:551-556
    • (2005) Genomics , vol.85 , pp. 551-556
    • Guntram, S.1    Bruford, E.2    Philipsen, S.3
  • 13
    • 0026657846 scopus 로고
    • Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene
    • Imataka H, Sogawa K, Yasumoto K, Kikuchi Y, Sasano K, Kobayashi A, Hayami M, Fujii-Kuriyama Y 1992 Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene. EMBO J 11:3663-3671
    • (1992) EMBO J , vol.11 , pp. 3663-3671
    • Imataka, H.1    Sogawa, K.2    Yasumoto, K.3    Kikuchi, Y.4    Sasano, K.5    Kobayashi, A.6    Hayami, M.7    Fujii-Kuriyama, Y.8
  • 14
    • 0030928821 scopus 로고    scopus 로고
    • Thyroid hormone-dependent gene expression program for Xenopus neural development
    • Denver RJ, Pavgi S, Shi YB 1997 Thyroid hormone-dependent gene expression program for Xenopus neural development. J Biol Chem 272:8179-8188
    • (1997) J Biol Chem , vol.272 , pp. 8179-8188
    • Denver, R.J.1    Pavgi, S.2    Shi, Y.B.3
  • 15
    • 0033551695 scopus 로고    scopus 로고
    • Basic transcription element binding protein (BTEB) is a thyroid hormone- regulated gene in the developing central nervous system: Evidence for a role in neurite outgrowth
    • Denver RJ, Ouellet L, Furling D, Kobayashi A, Fujii-Kuriyama Y, Puymirat J 1999 Basic transcription element binding protein (BTEB) is a thyroid hormone- regulated gene in the developing central nervous system: evidence for a role in neurite outgrowth. J Biol Chem 274:23128 -23134
    • (1999) J Biol Chem , vol.274 , pp. 23128-23134
    • Denver, R.J.1    Ouellet, L.2    Furling, D.3    Kobayashi, A.4    Fujii-Kuriyama, Y.5    Puymirat, J.6
  • 16
    • 0036411904 scopus 로고    scopus 로고
    • Basic transcription element binding protein is a thyroid hormone-regulated transcription factor expressed during metamorphosis in Xenopus laevis
    • Hoopfer ED, Huang LY, Denver RJ 2002 Basic transcription element binding protein is a thyroid hormone-regulated transcription factor expressed during metamorphosis in Xenopus laevis. Dev Growth Differ 44:365-381
    • (2002) Dev Growth Differ , vol.44 , pp. 365-381
    • Hoopfer, E.D.1    Huang, L.Y.2    Denver, R.J.3
  • 17
    • 0036098202 scopus 로고    scopus 로고
    • Suppression of the basic transcription element-binding protein in brain neuronal cultures inhibits thyroid hormone- induced neurite branching
    • Cayrou C, Denver RJ, Puymirat J 2002 Suppression of the basic transcription element-binding protein in brain neuronal cultures inhibits thyroid hormone- induced neurite branching. Endocrinology 143:2242-2249
    • (2002) Endocrinology , vol.143 , pp. 2242-2249
    • Cayrou, C.1    Denver, R.J.2    Puymirat, J.3
  • 19
    • 1842432620 scopus 로고    scopus 로고
    • Roles of corticotropin- releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis
    • Crespi EJ, Vaudry H, Denver RJ 2004 Roles of corticotropin- releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. J Neuroendocrinol 16:279 -288
    • (2004) J Neuroendocrinol , vol.16 , pp. 279-288
    • Crespi, E.J.1    Vaudry, H.2    Denver, R.J.3
  • 20
    • 34249782869 scopus 로고    scopus 로고
    • Structural and functional conservation of vertebrate corticotropin-releasing factor genes: Evidence for a critical role for a conserved cyclic AMP response element
    • Yao M, Stenzel-Poore M, Denver RJ 2007 Structural and functional conservation of vertebrate corticotropin-releasing factor genes: evidence for a critical role for a conserved cyclic AMP response element. Endocrinology 148:2518 -2531
    • (2007) Endocrinology , vol.148 , pp. 2518-2531
    • Yao, M.1    Stenzel-Poore, M.2    Denver, R.J.3
  • 21
    • 11244349864 scopus 로고    scopus 로고
    • Distribution and acute stressor- induced activation of corticotrophin-releasing hormone neurones in the central nervous system of Xenopus laevis
    • Yao M, Westphal NJ, Denver RJ 2004 Distribution and acute stressor- induced activation of corticotrophin-releasing hormone neurones in the central nervous system of Xenopus laevis. J Neuroendocrinol 16:880 -893
    • (2004) J Neuroendocrinol , vol.16 , pp. 880-893
    • Yao, M.1    Westphal, N.J.2    Denver, R.J.3
  • 22
    • 0020744309 scopus 로고
    • Seasonal and stress related changes in plasma gonadotropins, sex steroids, and corticosterone in the bullfrog, Rana catesbeiana
    • Licht P, McCreery BR, Barnes R, Pang R 1983 Seasonal and stress related changes in plasma gonadotropins, sex steroids, and corticosterone in the bullfrog, Rana catesbeiana. Gen Comp Endocrinol 50:124-145
    • (1983) Gen Comp Endocrinol , vol.50 , pp. 124-145
    • Licht, P.1    McCreery, B.R.2    Barnes, R.3    Pang, R.4
  • 23
    • 0031840102 scopus 로고    scopus 로고
    • Hormonal correlates of environmentally induced metamorphosis in the Western spadefoot toad, Scaphiopus hammondii
    • Denver RJ 1998 Hormonal correlates of environmentally induced metamorphosis in the Western spadefoot toad, Scaphiopus hammondii. Gen Comp Endocrinol 110:326 -336
    • (1998) Gen Comp Endocrinol , vol.110 , pp. 326-336
    • Denver, R.J.1
  • 24
    • 38349191360 scopus 로고    scopus 로고
    • A role for basic transcription element-binding protein 1 (BTEB1) in the autoinduction of thyroid hormone receptor β
    • Bagamasbad P, Howdeshell KL, Sachs LM, Demeneix BA, Denver RJ 2008 A role for basic transcription element-binding protein 1 (BTEB1) in the autoinduction of thyroid hormone receptor β. J Biol Chem 283:2275-2285
    • (2008) J Biol Chem , vol.283 , pp. 2275-2285
    • Bagamasbad, P.1    Howdeshell, K.L.2    Sachs, L.M.3    Demeneix, B.A.4    Denver, R.J.5
  • 25
    • 42549105085 scopus 로고    scopus 로고
    • Distribution and corticosteroid regulation of glucocorticoid receptor in the brain of Xenopus laevis
    • Yao M, Hu F, Denver RJ 2008 Distribution and corticosteroid regulation of glucocorticoid receptor in the brain of Xenopus laevis. J Comp Neurol 508:967-982
    • (2008) J Comp Neurol , vol.508 , pp. 967-982
    • Yao, M.1    Hu, F.2    Denver, R.J.3
  • 26
    • 0031960654 scopus 로고    scopus 로고
    • Distribution of pro-opiomelanocortin and its peptide end products in the brain and hypophysis of the aquatic toad, Xenopus laevis
    • Tuinhof R, Ubink R, Tanaka S, Atzori C, van Strien FJ, Roubos EW 1998 Distribution of pro-opiomelanocortin and its peptide end products in the brain and hypophysis of the aquatic toad, Xenopus laevis. Cell Tissue Res 292:251-265
    • (1998) Cell Tissue Res , vol.292 , pp. 251-265
    • Tuinhof, R.1    Ubink, R.2    Tanaka, S.3    Atzori, C.4    van Strien, F.J.5    Roubos, E.W.6
  • 27
    • 0018751062 scopus 로고
    • L-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone
    • L-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone. Endocrinology 105:80 -85
    • (1979) Endocrinology , vol.105 , pp. 80-85
    • Samuels, H.H.1    Stanley, F.2    Casanova, J.3
  • 28
    • 0027193739 scopus 로고
    • Cultured cells as a model for amphibian metamorphosis
    • Kanamori A, Brown DD 1993 Cultured cells as a model for amphibian metamorphosis. Proc Natl Acad Sci USA 90:6013-6017
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6013-6017
    • Kanamori, A.1    Brown, D.D.2
  • 29
    • 33745591642 scopus 로고    scopus 로고
    • Leptin (ob gene) of the South African clawed frog Xenopus laevis
    • Crespi EJ, Denver RJ 2006 Leptin (ob gene) of the South African clawed frog Xenopus laevis. Proc Natl Acad Sci USA 103:10092-10097
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10092-10097
    • Crespi, E.J.1    Denver, R.J.2
  • 30
    • 0036596186 scopus 로고    scopus 로고
    • Targeted electroporation in Xenopus tadpoles in vivo-from single cells to the entire brain
    • Haas K, Jensen K, Sin WC, Foa L, Cline HT 2002 Targeted electroporation in Xenopus tadpoles in vivo-from single cells to the entire brain. Differentiation 70:148-154
    • (2002) Differentiation , vol.70 , pp. 148-154
    • Haas, K.1    Jensen, K.2    Sin, W.C.3    Foa, L.4    Cline, H.T.5
  • 32
    • 0031128322 scopus 로고    scopus 로고
    • Environmental stress as a developmental cue: Corticotropin- releasing hormone is a proximate mediator of adaptive phenotypic plasticity in amphibian metamorphosis
    • Denver RJ 1997 Environmental stress as a developmental cue: corticotropin- releasing hormone is a proximate mediator of adaptive phenotypic plasticity in amphibian metamorphosis. Horm Behav 31:169 -179
    • (1997) Horm Behav , vol.31 , pp. 169-179
    • Denver, R.J.1
  • 33
    • 0036721475 scopus 로고    scopus 로고
    • The transcription factor basic transcription element-binding protein 1 is a direct thyroid hormone response gene in the frog Xenopus laevis
    • Furlow JD, Kanamori A 2002 The transcription factor basic transcription element-binding protein 1 is a direct thyroid hormone response gene in the frog Xenopus laevis. Endocrinology 143:3295-3305
    • (2002) Endocrinology , vol.143 , pp. 3295-3305
    • Furlow, J.D.1    Kanamori, A.2
  • 34
    • 58549113147 scopus 로고    scopus 로고
    • Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis
    • Denver RJ, Hu F, Scanlan TS, Furlow JD 2009 Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis. Dev Biol 326:155-168
    • (2009) Dev Biol , vol.326 , pp. 155-168
    • Denver, R.J.1    Hu, F.2    Scanlan, T.S.3    Furlow, J.D.4
  • 35
    • 42549137955 scopus 로고    scopus 로고
    • Evolutionarily conserved glucocorticoid regulation of corticotropin-releasing factor expression
    • Yao M, Schulkin J, Denver RJ 2008 Evolutionarily conserved glucocorticoid regulation of corticotropin-releasing factor expression. Endocrinology 149:2352-2360
    • (2008) Endocrinology , vol.149 , pp. 2352-2360
    • Yao, M.1    Schulkin, J.2    Denver, R.J.3
  • 36
    • 31844432025 scopus 로고    scopus 로고
    • Synaptic plasticity in the central nucleus of the amygdala
    • Samson RD, Duvarci S, Pare D 2005 Synaptic plasticity in the central nucleus of the amygdala. Rev Neurosci 16:287-302
    • (2005) Rev Neurosci , vol.16 , pp. 287-302
    • Samson, R.D.1    Duvarci, S.2    Pare, D.3
  • 37
    • 33845896778 scopus 로고    scopus 로고
    • Long-term potentiation in the amygdala: A cellular mechanism of fear learning and memory
    • Sigurdsson T, Doyere V, Cain CK, LeDoux JE 2007 Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memory. Neuropharmacology 52:215-227
    • (2007) Neuropharmacology , vol.52 , pp. 215-227
    • Sigurdsson, T.1    Doyere, V.2    Cain, C.K.3    LeDoux, J.E.4
  • 38
    • 0343750698 scopus 로고    scopus 로고
    • Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy
    • Conrad CD, Magarinos AM, LeDoux JE, McEwen BS 1999 Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav Neurosci 113:902-913
    • (1999) Behav Neurosci , vol.113 , pp. 902-913
    • Conrad, C.D.1    Magarinos, A.M.2    LeDoux, J.E.3    McEwen, B.S.4
  • 39
    • 0036703905 scopus 로고    scopus 로고
    • Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons
    • Vyas A, Mitra R, Rao BS, Chattarji S 2002 Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J Neurosci 22:6810 -6818
    • (2002) J Neurosci , vol.22 , pp. 6810-6818
    • Vyas, A.1    Mitra, R.2    Rao, B.S.3    Chattarji, S.4
  • 40
    • 44449109487 scopus 로고    scopus 로고
    • Acute corticosterone treatment is sufficient to induceanxiety and amygdaloid dendritic hypertrophy
    • Mitra R, Sapolsky RM 2008 Acute corticosterone treatment is sufficient to induceanxiety and amygdaloid dendritic hypertrophy. Proc Natl Acad Sci USA 105:5573-5578
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5573-5578
    • Mitra, R.1    Sapolsky, R.M.2
  • 41
    • 34547131302 scopus 로고    scopus 로고
    • Regulation of vertebrate corticotropin-releasing factor genes
    • Yao M, Denver RJ 2007 Regulation of vertebrate corticotropin-releasing factor genes. Gen Comp Endocrinol 153:200 -216
    • (2007) Gen Comp Endocrinol , vol.153 , pp. 200-216
    • Yao, M.1    Denver, R.J.2
  • 42
    • 0345465716 scopus 로고    scopus 로고
    • Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress
    • Magarinos AM, Deslandes A, McEwen BS 1999 Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. Eur J Pharmacol 371:113-122
    • (1999) Eur J Pharmacol , vol.371 , pp. 113-122
    • Magarinos, A.M.1    Deslandes, A.2    McEwen, B.S.3
  • 43
    • 0034619441 scopus 로고    scopus 로고
    • Sousa N, Lukoyanov NV, Madeira MD, Almeida OF, Paula-Barbosa MM 2000 Erratum to Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience 101:483
    • Sousa N, Lukoyanov NV, Madeira MD, Almeida OF, Paula-Barbosa MM 2000 Erratum to "Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement." Neuroscience 101:483
  • 44
    • 32644472066 scopus 로고    scopus 로고
    • Novel effects of CRF on visuomotor behavior and autonomic function in anuran amphibians
    • Carr JA 2006 Novel effects of CRF on visuomotor behavior and autonomic function in anuran amphibians. Gen Comp Endocrinol 146:28 -35
    • (2006) Gen Comp Endocrinol , vol.146 , pp. 28-35
    • Carr, J.A.1
  • 45
    • 0035252919 scopus 로고    scopus 로고
    • Dendritic arbor development and synaptogenesis
    • Cline HT 2001 Dendritic arbor development and synaptogenesis. Curr Opin Neurobiol 11:118-126
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 118-126
    • Cline, H.T.1
  • 46
    • 0036471970 scopus 로고    scopus 로고
    • Activity-dependent mapping in the retinotectal projection
    • Debski EA, Cline HT 2002 Activity-dependent mapping in the retinotectal projection. Curr Opin Neurobiol 12:93-99
    • (2002) Curr Opin Neurobiol , vol.12 , pp. 93-99
    • Debski, E.A.1    Cline, H.T.2
  • 47
    • 0038724939 scopus 로고    scopus 로고
    • Control of axon branch dynamics by correlated activity in vivo
    • Ruthazer ES, Akerman CJ, Cline HT 2003 Control of axon branch dynamics by correlated activity in vivo. Science 301:66-70
    • (2003) Science , vol.301 , pp. 66-70
    • Ruthazer, E.S.1    Akerman, C.J.2    Cline, H.T.3
  • 49
    • 3142700003 scopus 로고    scopus 로고
    • New spines, new memories
    • Leuner B, Shors TJ 2004 New spines, new memories. Mol Neurobiol 29:117-130
    • (2004) Mol Neurobiol , vol.29 , pp. 117-130
    • Leuner, B.1    Shors, T.J.2
  • 51
    • 0028179790 scopus 로고
    • Overexpression of the β-1 thyroid receptor induces differentiation in Neuro-2a cells
    • Lebel JM, Dussault JH, Puymirat J 1994 Overexpression of the β-1 thyroid receptor induces differentiation in Neuro-2a cells. Proc Natl Acad Sci USA 91:2644-2648
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2644-2648
    • Lebel, J.M.1    Dussault, J.H.2    Puymirat, J.3
  • 52
    • 0012863765 scopus 로고
    • The Golgi method: Its application to the insect nervous system and the phenomenon of stochastic impregnation
    • Strausfeld NJ, Miller, TA, eds, New York: Springer-Verlag;
    • Strausfeld NJ 1980 The Golgi method: its application to the insect nervous system and the phenomenon of stochastic impregnation. In: Strausfeld NJ, Miller, TA, eds. Neuroanatomical techniques: insect nervous system. New York: Springer-Verlag; 132-205
    • (1980) Neuroanatomical techniques: Insect nervous system , pp. 132-205
    • Strausfeld, N.J.1
  • 53
    • 36549075574 scopus 로고    scopus 로고
    • Synaptic plasticity: Multiple forms, functions, and mechanisms
    • Citri A, Malenka RC 2008 Synaptic plasticity: multiple forms, functions, and mechanisms. Neuropsychopharmacology 33:18 -41
    • (2008) Neuropsychopharmacology , vol.33 , pp. 18-41
    • Citri, A.1    Malenka, R.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.