Intravenous midazolam in convulsive status epilepticus in children with pharmacoresistant epilepsy

Epilepsy and Behavior

Volumn 14, Issue 4, 2009, Pages 661-664

  Papavasiliou, Antigone S ^a   Kotsalis, Charalambos ^a   Paraskevoulakos, Evangelos ^a   Karagounis, Panagiotis ^a   Rizou, Chrysoula ^a   Bazigou, Helene ^a  

^a PENTELI CHILDREN S HOSPITAL   (Greece)

Author keywords

Midazolam; Status epilepticus

Indexed keywords

ANTICONVULSIVE AGENT; CLONAZEPAM; MIDAZOLAM; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

ADOLESCENT; ARTICLE; ASSISTED VENTILATION; CARDIOVASCULAR DISEASE; CHILD; CHILD HEALTH CARE; CLINICAL PROTOCOL; CONTINUOUS INFUSION; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; EPILEPTIC STATE; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MEDICAL AUDIT; REPEATED DRUG DOSE; RESPIRATION DEPRESSION;

ADOLESCENT; ANTI-ANXIETY AGENTS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAVENTRICULAR; MALE; MIDAZOLAM; SEVERITY OF ILLNESS INDEX; STATUS EPILEPTICUS; TREATMENT OUTCOME;

EID: 63749094812     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2009.02.018     Document Type: Article

References (28)

1. Shorvon S.D., and Walker M.C. Tonic-clonic status epilepticus. In: Hughes R.A. (Ed). Neurological emergencies. 3rd ed. (2000), BMJ, London 143-172
2. Evrard P., Arzimanoglou A., Husson I., Gressens P., and Sankar R. Management of status epilepticus in infants and children. In: Wasterlain C.G., and Treiman D.M. (Eds). Status epilepticus: mechanisms and management (2006), MIT Press, Cambridge, MA/London 515-521
3. Scott R.C., Surtees R.A.H., and Neville B.G.R. Status epilepticus: pathophysiology, epidemiology, and outcomes. Arch Dis Child 79 (1998) 73-77
4. Lowenstein D.H., Bleck T., and Macdonald R.L. It's time to revise the definition of status epilepticus. Epilepsia 40 (1999) 120-122
5. Scott R.C., and Kirkham F.J. Clinical update: childhood convulsive status epilepticus. Lancet 370 (2007) 724-726
6. Beran R.G. An alternative perspective on the management of status epilepticus. Epilepsy Behav 12 (2008) 349-353
7. Treiman D.M. Therapy of status epilepticus in adults and children. Curr Opin Neurol 14 (2001) 203-210
8. Rivera R., Segnini M., Bartodamo A., and Perez V. Midazolam in the treatment of status epilepticus in children. Crit Care Med 21 (1993) 991-994
9. Pellock J.M., Marmarou A., and DeLorenzo R. Time to treatment in prolonged seizure episodes. Epilepsy Behav 5 (2004) 192-196
10. Noe K.H., and Manno E.M. Mechanisms underlying status epilepticus: an in-depth review of the pathophysiology of status epilepticus and how it relates to pharmacologic treatment. Drugs Today (Barc) 41 (2005) 257-266
11. Najam Y., McDonald D.G., Keegan M., Webb D.W., and McMenamin J.B. Audit of the management of convulsive status epilepticus in children: the need for a uniform treatment strategy. Ir Med J 97 (2004) 246-248
12. Rona S., Rosenow F., Arnold S., et al. A semiological classification of status epilepticus. Epileptic Disord 7 (2005) 5-12
13. Riviello Jr. J.J., and Holmes G.L. The treatment of status epilepticus. Semin Pediatr Neurol 11 (2004) 129-138
14. Morrison G., Gibbons E., and Whitehouse W.P. High-dose midazolam therapy for refractory status epilepticus in children. Intens Care Med 32 (2006) 2070-2076
15. Hayashi K., Osawa M., Aihara M., et al. Efficacy of intravenous midazolam for status epilepticus in childhood. Pediatr Neurol 36 (2007) 366-372
16. Hamano S., Tanaka M., Mochizuki M., Sugiyama N., and Eto Y. Midazolam treatment for status epilepticus of children. No To Hattatsu 35 (2003) 304-309
17. Minagawa K., and Watanabe T. Eight-year study on the treatment with intravenous midazolam for status epilepticus and clusters of seizures in children. No To Hattatsu 35 (2003) 484-490
18. Yoshikawa H., Yamazaki S., Abe T., and Oda Y. Midazolam as a first-line agent for status epilepticus in children. Brain Dev 22 (2000) 239-242
19. Singhi S., Murthy A., Singhi P., and Jayasharee M. Continuous midazolam versus diazepam infusion for refractory convulsive status epilepticus. J Child Neurol 17 (2002) 106-110
20. Koul R.L., Aithala G.R., Chako A., Joshi R., and Elbualy M.S. Continuous midazolam infusion as treatment of status epilepticus. Arch Dis Child 76 (1997) 445-448
21. Kumar A., and Bleck T.P. Intravenous midazolam for the treatment of refractory status epilepticus. Crit Care Med 20 (1992) 483-488
22. Parent J.M., and Lowenstein D.H. Treatment of refractory generalized status epilepticus with continuous infusion of midazolam. Neurology 44 (1994) 1837-1840
23. Bebin M., and Bleck T.P. New anticonvulsant drugs: focus on flunarizine, fosphenytoin, midazolam and stiripentol. Drugs 48 (1994) 153-171
24. Naritoku D.K., and Sinha S. Prolongation of midazolam half-life after sustained infusion for status epilepticus. Neurology 54 (2000) 1366-1368
25. Goldstein J. Status epilepticus in the pediatric emergency department. Clin Pediatr Emerg Med 9 (2008) 96-100
26. Lahat E., Aladjem M., Eshel G., Bistritzer T., and Katz Y. Midazolam in treatment of epileptic seizures. Pediatr Neurol 8 (1992) 215-216
27. Scott R.C., Besag F.M.C., and Neville B.G.R. Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence. A randomised trial. Lancet 353 (1999) 623-626
28. Lahat E., Goldman M., Barr J., Bistritzer T., and Berkovitch M. Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study. Br Med J 321 (2000) 83-86