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Volumn 50, Issue 21, 2009, Pages 2474-2477

Synthetic studies towards the novel neurotrophic diterpenoids neovibsanins A and B: construction of the ABC core

Author keywords

[No Author keywords available]

Indexed keywords

ALDOLVIBSANIN B; CYCLOVIBSANIN A; DITERPENOID; FURANOVIBSANIN D; NATURAL PRODUCT; NEOVIBSANIN A; NEOVIBSANIN B; NEOVIBSANIN H; SPIROVIBSANIN A; UNCLASSIFIED DRUG; VIBSANIN B; VIBSANIN C; VIBSANIN E; VIBSANIN O;

EID: 63749086312     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.03.040     Document Type: Article
Times cited : (44)

References (19)
  • 9
    • 33746098889 scopus 로고    scopus 로고
    • Vibsanin diterpenoids have evoked considerable interest from synthetic chemists, see and references cited therein
    • Vibsanin diterpenoids have evoked considerable interest from synthetic chemists, see. Schwartz B.D., Tilly D.P., Heim R., Wiedemann S., Williams C.M., and Bernhardt P.V. Eur. J. Org. Chem. (2006) 3181-3192 and references cited therein
    • (2006) Eur. J. Org. Chem. , pp. 3181-3192
    • Schwartz, B.D.1    Tilly, D.P.2    Heim, R.3    Wiedemann, S.4    Williams, C.M.5    Bernhardt, P.V.6
  • 16
    • 63749083611 scopus 로고    scopus 로고
    • note
    • In this context, it is important to mention that propargyl addition to the allylated compound 27 was dominated by steric considerations with preferred addition from the less hindered opposite face to furnish exclusively 48 having the undesired stereochemical disposition at C-4 and C-10. Thus, we devised the tactic of using the acetal oxygen in 29 to coordinate with the organolithium reagent and deliver the propargyl group from the same face by partially overcoming the steric barrier.{A figure is presented}
  • 17
    • 63749095924 scopus 로고    scopus 로고
    • note
    • 2 = 0.2757, GOF = 0.9550 for all data.
  • 19
    • 63749091342 scopus 로고    scopus 로고
    • note
    • +): 299.1623; found: 299.1611.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.