Dose- and time-dependent effects of ethanolic extract of Mucuna pruriens Linn. seed on sexual behaviour of normal male rats

Journal of Ethnopharmacology

Volumn 122, Issue 3, 2009, Pages 497-501

  Suresh, Sekar ^a   Prithiviraj, Elumalai ^a   Prakash, Seppan ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Aphrodisiac; Ethanolic extract; Libido; Mucuna pruriens Linn; Potency; Sexual behaviour

Indexed keywords

ESTRADIOL; MUCUNA PRURIENS EXTRACT; PLANT EXTRACT; SILDENAFIL; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EJACULATION; ESTRUS; FEMALE; HORMONE DETERMINATION; LIBIDO; MALE; MATING; NONHUMAN; PENIS ERECTION; PLANT SEED; RAT; SEMEN ANALYSIS; SEXUAL BEHAVIOR; STOMACH ULCER; TOXICITY TESTING; VELVET BEAN;

ANIMALS; APHRODISIACS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; FLOWERS; LIBIDO; MALE; MUCUNA; ORGAN SIZE; PIPERAZINES; PLANT EXTRACTS; PURINES; RATS; RATS, WISTAR; SEEDS; SEXUAL BEHAVIOR, ANIMAL; SPERMATOZOA; SULFONES; TESTOSTERONE; VASODILATOR AGENTS;

ANIMALIA; MUCUNA PRURIENS; PAPILIONOIDEAE; RATTUS;

EID: 63649141240     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.01.032     Document Type: Article

References (24)

1. Adebowale Y.A., Adeyemi A., and Oshodi A.A. Variability in the physicochemical, nutritional and antinutritional attributes of six Mucuna species. Food Chemistry 89 (2005) 37-48
2. Agmo A. Male rat sexual behaviour. Brain Research Protocols 1 (1997) 203-209
3. Amin K.M.Y., Khan M.N., Rahman S.Z., and Khan N.A. Sexual function improving effect of Mucuna pruriens in sexually normal male rats. Fitoterapia 67 (1996) 53-58
4. Anletta F.J. In: Jaffe B.M., and Behram N.R. (Eds). Methods of Hormone Radio Immunoassay (1974), Academic Press, New York p. 520
5. Beach F.A. Characteristics of masculine. Sex drive. In: Jones M.R. (Ed). Nebraska Symposium on Motivation (1956), University of Nebraska Press, Lincoln pp. 1-31
6. Cioli V., Silvestrini B., and Dordoni F. Evaluation of potential of gastric ulceration after administration of certain drugs. Experimental Molecular Pathology 6 (1967) 68-75
7. Davidson J.M. In: Zewi H. (Ed). Sexology, sexual biology, behaviour and therapy: selected papers of Fifth World Congress of sexology Jerusalem 1981. Amsterdam, Holland. Excerpta Medica, Princeton, Oxford (1982) pp. 42-47
8. Elaine M.H., John W.M., and Satoru S. Dopamine and serotonin: influences on male sexual behavior. Physiology and Behavior 83 (2004) 291-307
9. Emmanuele A.J., Francesco L., Pietro S., Loredana G., and Andrea L. Treatment of sexual dysfunctions secondary to male infertility with sildenafil citrate. Fertility and Sterility 81 (2004) 705-707
10. Harborne J.B. Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis (1973), Chapman and Hall International, London pp. 105-185
11. Hart B.L. Activation of sexual reflexes in male rats by dihydrotestosterone but not estrogen. Physiology and Behaviour 23 (1979) 107-109
12. Hart B.L., and Haugen C.M. Activation of sexual reflexes in male rats by spinal implementation of testosterone. Physiology and Behaviour 3 (1968) 735-738
13. Kharelep C.P. Encyclopedia of Indian Medicinal Plants (Regional Western Therapy Ayurvedic and Other Traditional Usage, Botany) (2004), Springer-Verlag, Berlin Heidelberg, New York pp. 318-319
14. Misra L., and Wagner H. Alkaloidal constituents of Mucuna pruriens seeds. Phytochemistry 65 (2004) 2565-2567
15. McGinnis M.Y., Mirth M.C., Zebrowski A.F., and Dreifuss R.M. Critical exposure time for androgen activation of male sexual behavior in rats. Physiology and Behavior 46 (1989) 159-165
16. Nagashayana N., Sankarankutty P., Nampoothiri M.R.V., Mohan P.K., and Mohanakumar K.P. Association of l-DOPA with recovery following ayurveda medication in Parkinson's disease. Journal of the Neurological Sciences 176 (2000) 124-127
17. Pant M.C., and Joshi L.D. Identification of pharmacologically active substances in the seeds of Mucuna pruriens (Abs). Proceedings of the Annual Conference of Indian Pharmacological Society, Lucknow, India. Indian Journal of Pharmacology 2 (1970) 24
18. Rao M.R., and Parakh S.R. Effect of some indigenous drugs on the sexual behaviour of male rats. Indian Journal of Pharmacological Sciences 40 (1978) 236
19. Rathi S.S., Grover J.K., and Vats V. The effect of Momordica charantia and Mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism. Phytotherapy Research 163 (2002) 236-243
20. Rowland D.L., and Tai W. A review of plant-derived and herbal approaches to the treatment of sexual dysfunctions. Journal Sex and Marital Therapy 29 (2003) 185-205
21. Saksena S., and Dixit V.K. Role of total alkaloids of Mucucna pruriens bark in spermatogenesis in albino rats. Indian Journal of Natural Products 3 (1987) 3-37
22. Siddhuraju P., Vijayakumari K., and Janardhanan K. Chemical composition and protein quality of the little known legume, velvet bean (Mucuna pruriens (L.) DC.). Journal Agriculture Food Chemistry 44 (1996) 2636-2641
23. Suresh Kumar P.K., Subramoniam A., and Pushpangadan P. Aphrodiasiac activity of Vanda tessellata (ROXB.) HOOK. EXDON. extract in male mice. Indian Journal of Pharmacology 32 (2000) 300-304
24. WHO. Laboratory Manual for Examination of Human Semen and Semen-cervical Mucus Interaction. 2nd ed. (1987), World Health Organization by Cambridge University Press pp. 9-10