Taste masking by spray-drying technique

AAPS PharmSciTech

Volumn 9, Issue 4, 2008, Pages 1159-1164

  Bora, Divyakumar ^a   Borude, Priyanka ^a   Bhise, Kiran ^a  

^a Allana College of Pharmacy   (India)

Author keywords

Microspheres; Spray drying; Taste masking

Indexed keywords

CHITOSAN; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; MICROSPHERE; ONDANSETRON; SEROTONIN ANTAGONIST;

ARTICLE; BITTER TASTE; CONTROLLED STUDY; DRUG COATING; DRUG FORMULATION; DRUG MIXTURE; DRUG RELEASE; INFRARED SPECTROSCOPY; MASKING; MOISTURE; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; TASTE ACUITY; TASTE MASKING; CHEMISTRY; DRUG EFFECT; PERCEPTIVE THRESHOLD; TASTE;

MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; ONDANSETRON; SENSORY THRESHOLDS; SEROTONIN ANTAGONISTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TASTE;

EID: 63649137129     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9154-5     Document Type: Article

References (18)

1. T. Jacob. Taste - A brief tutorial by Tim Jacob. http://www.cf.ac.uk/ biosi/staff/jacob/teaching/sensory/taste.html, 23 Aug 2006.
2. R. A. Romanov, and S. S. Kolesnikov. Electrophysiologically identified subpopulations of taste bud cells. Neurosci. Lett. 395:249-254 (2006).
3. H. Sohi, Y. Sultana, and R. K. Khar. Taste masking technologies in oral pharmaceuticals: Recent developments and approaches. Drug Dev. Ind. Pharm. 30:429-448 (2004).
4. Y. Gao, F. Cui, Y. Guan, L. Yang, Y. Wang, and L. Zhang. Preparation of roxithromycin-polymeric microspheres by the emulsion solvent diffusion method for taste masking. Int. J. Pharm. 318:62-69 (2006).
5. R. W. Shen. Taste masking of ibuprofen by fluid bed coating. US Patent 5, 55,152, September 3, 1996.
6. M. L. Lorenzo-Lamosa, M. Kuna, and J. Vila Jato. Development of microencapsulated form of Cefuroxime axetil using pH sensitive acrylic polymers. J. Microencapsule. 14:660-616 (1997).
7. S. Khan, P. Katariya, P. Nakhat, and P. Yeole. Taste masking of ondansetron hydrochloride by polymer carrier system and formulation of rapid disintegrating tablets. AAPS PharmsciTech. 8(2):E1-E7 (2007).
8. S. P. Manek, and V. S. Kamat. Evaluation of Indion CRP-244 and CRP-254 as sustained release and taste masking agents. Indian J. Pharm. Sci. 43(11-12):209-212 (1981).
9. S. Borodkin, and D. P. Sundberg. Polycarboxylic acid ion-exchange resin adsorbates for taste coverage in chewable tablets. J. Pharm. Sci. 60:1523-1527 (1971).
10. M. Sriwongjanya, and R. Bodmeier. Entrapment of drug loaded ion-exchange particles within polymer microparticles. Int. J. Pharm. 158:29-38 (1997).
11. J. Szejtli, and L. Szente. Elimination of bitter, distinguishing taste of drugs and foods by cyclodextrins. Eur. J. Pharm. Biopharm. 61:115-125 (2005).
12. E. H. Cox, C. V. Follet, S. L. Beal, E. Fuseau, S. Kenkare, and L.W. Sheiner. A population pharmacokinetic-pharmacodynamic analysis of repeated measures time-to-event pharmacodynamic responses: The antiemetic effect of ondansetron. J. Pharmacoknet. Biopharm. 27(6):635-644 (1999).
13. B. A. Johnson, J. Rue, and P. J. Cowen. Ondansetron and alcohol pharmacokinetis. Psychopharmacology. 112:145 (1993).
14. R. C. Rowe, P. J. Sheskey, and S. C. Owen. Handbook of Pharmaceutical excipients, 4th ed., KM Varghese Company, Mumbai, 2004.
15. A. M. Goula, T. D. Karapantsios, D. S. Achilias, and K. G. Adamopoulos. Water sorption isotherms and glass transition temperature of spray dried tomato pulp. J. Food Sci. 85:78-83 (2008).
16. B. Albertini, C. Cavallari, N. Passerini, D. Voinovich, M. L. Rodriguez, L. Magarotto, and L. Rodriguez. Characterization and taste masking evaluation of acetaminophen granules: Comparison between different preparation methods in a high shear mixer. Eur. J. Pharm. Sci. 21:295-303 (2004).
17. W. Chang, J. W. Chung, Y. Kim, S. Chung, and H. Kho. The relationship between phenylthiocarbamide (PTC) and 6- n -propylthiouracil (PROP) taster status and taste thresholds for sucrose and quinine. Arch. Oral Biol. 51:427-432 (2006).
18. The United Stated Pharmacopeia XXIII/National Formulary XVIII. US Pharmacopoeial convention, Rockville, MD, 1980:2800.