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Volumn 9, Issue 4, 2008, Pages 1110-1118

γ-irradiation of PEGd,lPLA and PEG-PLGA multiblock copolymers: II. Effect of oxygen and EPR investigation

Author keywords

Ionizing radiation; Multiblock copolymer; Polymer stability; Radicals; Radiolysis mechanism

Indexed keywords

COPOLYMER; OXYGEN; POLYGLACTIN; POLYLACTIDE; LACTIC ACID; MACROGOL DERIVATIVE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

EID: 63649132302     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9150-9     Document Type: Article
Times cited : (27)

References (24)
  • 1
    • 68249160319 scopus 로고
    • The use of ionizing radiation in the manufacture of medicinal products
    • European Medicines Agency
    • European Medicines Agency. The use of ionizing radiation in the manufacture of medicinal products European Guidelines 3AQ4a. (1991).
    • (1991) European Guidelines 3AQ4a
  • 2
    • 5044223434 scopus 로고    scopus 로고
    • Degradation of poly(lactide-co-glycolide) (PLGA) and poly(L-lactide) (PLLA) by electron beam radiation
    • J. S. C. Loo, C. P. Ooi, and F. Y. C Boey. Degradation of poly(lactide-co-glycolide) (PLGA) and poly(L-lactide) (PLLA) by electron beam radiation. Biomaterials. 26:1359-1367 (2005).
    • (2005) Biomaterials. , vol.26 , pp. 1359-1367
    • Loo, J.S.C.1    Ooi, C.P.2    Boey, F.Y.C.3
  • 4
    • 28244495873 scopus 로고    scopus 로고
    • An EPR and ENDOR study of gamma and beta-radiation sterilization in poly(lactide-co-glycolide) polymers and microspheres
    • J. A. Bushell, M. Claybourn, H. E. Williams, and D. M. Murphy. An EPR and ENDOR study of gamma and beta-radiation sterilization in poly(lactide-co-glycolide) polymers and microspheres. J. Control. Release. 110(1):49-57 (2005).
    • (2005) J. Control. Release. , vol.110 , Issue.1 , pp. 49-57
    • Bushell, J.A.1    Claybourn, M.2    Williams, H.E.3    Murphy, D.M.4
  • 6
    • 0037406071 scopus 로고    scopus 로고
    • Radiation induced free radical reactions in polymer/drug systems for controlled release: An EPR investigation
    • A. Faucitano, A. Buttafava, L. Montanari, F. Cilurzo, B. Conti, I. Genta, and L. Valvo. Radiation induced free radical reactions in polymer/ drug systems for controlled release: An EPR investigation. Radiat. Phys. Chem. 67:61-72 (2003).
    • (2003) Radiat. Phys. Chem. , vol.67 , pp. 61-72
    • Faucitano, A.1    Buttafava, A.2    Montanari, L.3    Cilurzo, F.4    Conti, B.5    Genta, I.6    Valvo, L.7
  • 8
    • 33846982918 scopus 로고    scopus 로고
    • Effect of different γ-irradiation doses on cytotoxicity and material properties of porous polyether-urethane polymer
    • H. J. Haugen, M. Brunner, F. Pellkofer, J. Aigner, J. Will, and E. Wintermantel. Effect of different γ-irradiation doses on cytotoxicity and material properties of porous polyether-urethane polymer. J. Biomed. Mater. Res. B. Appl. Biomate. 80B(2):415-423 (2006).
    • (2006) J. Biomed. Mater. Res. B. Appl. Biomate. , vol.80 B , Issue.2 , pp. 415-423
    • Haugen, H.J.1    Brunner, M.2    Pellkofer, F.3    Aigner, J.4    Will, J.5    Wintermantel, E.6
  • 9
    • 0043158940 scopus 로고    scopus 로고
    • Electron magnetic resonance study of gamma-irradiated poly(lactide-co-glycolide) microspheres
    • M. Claybourn, H. Gray, D. M. Murphy, I. J. Purnell, and C. C. Rowlands. Electron magnetic resonance study of gamma-irradiated poly(lactide-co-glycolide) microspheres. J. Control. Release. 91(3):431-438 (2003).
    • (2003) J. Control. Release. , vol.91 , Issue.3 , pp. 431-438
    • Claybourn, M.1    Gray, H.2    Murphy, D.M.3    Purnell, I.J.4    Rowlands, C.C.5
  • 10
    • 0030883127 scopus 로고    scopus 로고
    • Influence of irradiation sterilization on polymers used as drug carriers - A review
    • M. M. B. Sintzel, A. Merkli, C. Tabatabay, and R. Gurny. Influence of irradiation sterilization on polymers used as drug carriers - a review. Drug Dev. Ind. Pharm. 23(9):857-878 (1997).
    • (1997) Drug Dev. Ind. Pharm. , vol.23 , Issue.9 , pp. 857-878
    • Sintzel, M.M.B.1    Merkli, A.2    Tabatabay, C.3    Gurny, R.4
  • 11
    • 0030927086 scopus 로고    scopus 로고
    • The influence of gamma irradiation on the physicochemical properties of a novel triblock copolymer of ε-caprolactone and ethylene oxide
    • L. Martini, J. H. Collett, and D. Attwood. The influence of gamma irradiation on the physicochemical properties of a novel triblock copolymer of ε-caprolactone and ethylene oxide. J. Pharm. Pharmacol. 49(6):601-605 (1997).
    • (1997) J. Pharm. Pharmacol. , vol.49 , Issue.6 , pp. 601-605
    • Martini, L.1    Collett, J.H.2    Attwood, D.3
  • 14
    • 32644446161 scopus 로고    scopus 로고
    • The effect of gamma irradiation and shelf aging in air on the oxidation of ultra-high molecular weight polyethylene
    • M. A. Al-Ma'adeed, I. Y. Al-Qaradawi, N. Madi, and N. J. Al-Thani. The effect of gamma irradiation and shelf aging in air on the oxidation of ultra-high molecular weight polyethylene. Appl. Surf. Sci. 252(9):292 (2006).
    • (2006) Appl. Surf. Sci. , vol.252 , Issue.9 , pp. 292
    • Al-Ma'adeed, M.A.1    Al-Qaradawi, I.Y.2    Madi, N.3    Al-Thani, N.J.4
  • 16
    • 0035218387 scopus 로고    scopus 로고
    • PLGA microsphere bioburden evaluation for radiosterilization dose selection
    • A. Gèze, M. C. Venier-Julienne, J. Cottin, N. Faisant, and J. P. Benoit. PLGA microsphere bioburden evaluation for radiosterilization dose selection. J. Microencapsul. 18(5):627-636 (2001).
    • (2001) J. Microencapsul. , vol.18 , Issue.5 , pp. 627-636
    • Gèze, A.1    Venier-Julienne, M.C.2    Cottin, J.3    Faisant, N.4    Benoit, J.P.5
  • 17
    • 0036124641 scopus 로고    scopus 로고
    • Comparison of electron beam irradiation with gamma processing for medical packaging materials
    • L. Woo, and C. L. Sandford. Comparison of electron beam irradiation with gamma processing for medical packaging materials. Radiat. Phys. Chem. 63:845-850 (2002).
    • (2002) Radiat. Phys. Chem. , vol.63 , pp. 845-850
    • Woo, L.1    Sandford, C.L.2
  • 18
    • 0025102704 scopus 로고
    • The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state
    • C. Ahlneck, and G. Zografi. The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state. Int. J. Pharm. 62(2-3):87-95 (1990).
    • (1990) Int. J. Pharm. , vol.62 , Issue.2-3 , pp. 87-95
    • Ahlneck, C.1    Zografi, G.2
  • 19
    • 0027174285 scopus 로고
    • Molecular mobility in mixtures of absorbed water and solid poly(vinylpyrrolidone)
    • C. A. Oksanen, and G. Zografi. Molecular mobility in mixtures of absorbed water and solid poly(vinylpyrrolidone). Pharm. Res. 10(6):791-799 (1993).
    • (1993) Pharm. Res. , vol.10 , Issue.6 , pp. 791-799
    • Oksanen, C.A.1    Zografi, G.2
  • 20
    • 0028268210 scopus 로고
    • The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids
    • B. C. Hancock, and G. Zografi. The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids. Pharm. Res. 11(4):471-477 (1994).
    • (1994) Pharm. Res. , vol.11 , Issue.4 , pp. 471-477
    • Hancock, B.C.1    Zografi, G.2
  • 21
    • 0035132914 scopus 로고    scopus 로고
    • The influence of gamma irradiation and aging on degradation mechanisms of ultra-high molecular weight polyethylene
    • F. J. Buchanan, J. R. White, B. Sim, and S. Downes. The influence of gamma irradiation and aging on degradation mechanisms of ultra-high molecular weight polyethylene. J. Mater. Sci: Mater. Med. 12(1):29-37 (2001).
    • (2001) J. Mater. Sci: Mater. Med. , vol.12 , Issue.1 , pp. 29-37
    • Buchanan, F.J.1    White, J.R.2    Sim, B.3    Downes, S.4
  • 22
    • 0037180033 scopus 로고    scopus 로고
    • Alanine radicals 2. The composite polycrystalline alanine EPR spectrum studied by ENDOR, thermal annealing, and spectrum simulation
    • M. Z. Heydari, E. Malinen, E. O. Hole, and E. Sagstuen. Alanine radicals 2. The composite polycrystalline alanine EPR spectrum studied by ENDOR, thermal annealing, and spectrum simulation. J. Phys. Chem. A. 106:8971-8977 (2002).
    • (2002) J. Phys. Chem. A. , vol.106 , pp. 8971-8977
    • Heydari, M.Z.1    Malinen, E.2    Hole, E.O.3    Sagstuen, E.4
  • 23
    • 0000393184 scopus 로고
    • Electron spin resonance investigation of intramolecular hydrogen transfer and alkyl attack in ester cation radicals
    • D. Becker, S. Swart, and M. D. Sevilla. Electron spin resonance investigation of intramolecular hydrogen transfer and alkyl attack in ester cation radicals. J. Phys. Chem. 89(12):2638-2646 (1985).
    • (1985) J. Phys. Chem. , vol.89 , Issue.12 , pp. 2638-2646
    • Becker, D.1    Swart, S.2    Sevilla, M.D.3
  • 24
    • 50749133730 scopus 로고
    • The mechanism of gamma-radiolysis of polymethylene, polypropylene and poly-n-butylene oxides: An ESR investigation
    • A. Faucitano, A. Buttafava, F. Martinotti, P. Ferloni, and A. Magistris. The mechanism of gamma-radiolysis of polymethylene, polypropylene and poly-n-butylene oxides: An ESR investigation. Radiat. Phys. Chem. 40(5):347-355 (1992).
    • (1992) Radiat. Phys. Chem. , vol.40 , Issue.5 , pp. 347-355
    • Faucitano, A.1    Buttafava, A.2    Martinotti, F.3    Ferloni, P.4    Magistris, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.