A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo

Circulation Research

Volumn 104, Issue 5, 2009, Pages 650-659

  Meder, Benjamin ^a   Laufer, Christina ^a   Hassel, David ^a   Just, Steffen ^a   Marquart, Sabine ^a   Vogel, Britta ^a   Hess, Alexander ^a   Fishman, Mark C ^b   Katus, Hugo A ^a   Rottbauer, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Essential cardiac myosin light chain 1; Genetics; Myocardial contractility; Phosphorylation; Zebrafish

Indexed keywords

CARDIAC MYOSIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 1; NUCLEIC ACID BINDING PROTEIN; PROTEIN LAZ; SERINE; UNCLASSIFIED DRUG; CMLC1 PROTEIN, ZEBRAFISH; ETHYLNITROSOUREA; MUTAGENIC AGENT; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; GENE OVEREXPRESSION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IN VIVO STUDY; NONHUMAN; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; ZEBRA FISH; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HEART; HEART CONTRACTION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MUSCLE STRENGTH; PHOSPHORYLATION; PRENATAL DEVELOPMENT; PROTEIN TERTIARY STRUCTURE; SARCOMERE; SEQUENCE HOMOLOGY; STOP CODON; TIME;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CODON, NONSENSE; ETHYLNITROSOUREA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HEART; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUSCLE STRENGTH; MUTAGENS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; MYOSIN LIGHT CHAINS; PHENOTYPE; PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SARCOMERES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; TIME FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 63649105806     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.186676     Document Type: Article

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