메뉴 건너뛰기




Volumn 20, Issue 4, 2009, Pages 655-659

Neo-adjuvant exemestane in elderly patients with breast cancer: A phase II, multicentre, open-label, Italian study

Author keywords

Aromatase inhibitor; Breast cancer; Endocrine therapy; Exemestane; Neo adjuvant

Indexed keywords

EXEMESTANE;

EID: 63549102924     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn687     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 33748740822 scopus 로고    scopus 로고
    • NORA Study Group. Adjuvant systemic treatment of early breast cancer: The NORA study
    • Cazzaniga ME, Mustacchi G, Pronzato P et al. NORA Study Group. Adjuvant systemic treatment of early breast cancer: The NORA study. Ann Oncol 2006; 17: 1386-1392.
    • (2006) Ann Oncol , vol.17 , pp. 1386-1392
    • Cazzaniga, M.E.1    Mustacchi, G.2    Pronzato, P.3
  • 2
    • 12244294506 scopus 로고    scopus 로고
    • Tamoxifen alone versus adjuvant tamoxifen for operable breast cancer of the elderly: Long-term results of the phase III randomized controlled multicenter GRETA trial
    • Mustacchi G, Ceccherini R, Milani S et al. Tamoxifen alone versus adjuvant tamoxifen for operable breast cancer of the elderly: Long-term results of the phase III randomized controlled multicenter GRETA trial. Ann Oncol 2003; 14: 414-420.
    • (2003) Ann Oncol , vol.14 , pp. 414-420
    • Mustacchi, G.1    Ceccherini, R.2    Milani, S.3
  • 3
    • 34548416486 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy for locally advanced breast cancer
    • Ma CX, Ellis MJ. Neoadjuvant endocrine therapy for locally advanced breast cancer. Semin Oncol 2006; 33: 650-656.
    • (2006) Semin Oncol , vol.33 , pp. 650-656
    • Ma, C.X.1    Ellis, M.J.2
  • 4
    • 27244443082 scopus 로고    scopus 로고
    • Proliferation marker Ki-67 in early breast cancer
    • Urruticoechea J, Smith IE, Dowsett M. Proliferation marker Ki-67 in early breast cancer. J Clin Oncol 2005; 23: 7212-7220.
    • (2005) J Clin Oncol , vol.23 , pp. 7212-7220
    • Urruticoechea, J.1    Smith, I.E.2    Dowsett, M.3
  • 5
    • 0001909098 scopus 로고    scopus 로고
    • Tamoxifen versus surgery plus tamoxifen as primary treatment for elderly patients with breast cancer: Combined data from the "GRETA" and "CRC" trials
    • Abstr 383
    • Mustacchi G, Latteier J, Milani S et al. Tamoxifen versus surgery plus tamoxifen as primary treatment for elderly patients with breast cancer: combined data from the "GRETA" and "CRC" trials. Proc Am Soc Clin Oncol 1998; 17: 99a (Abstr 383).
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Mustacchi, G.1    Latteier, J.2    Milani, S.3
  • 6
    • 37349009057 scopus 로고    scopus 로고
    • Recommendation from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: New perspectives 2006
    • Kaufmann M, von Minckwitz G, Bear HD et al. Recommendation from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: New perspectives 2006. Ann Oncol 2007; 18: 1927-1934.
    • (2007) Ann Oncol , vol.18 , pp. 1927-1934
    • Kaufmann, M.1    von Minckwitz, G.2    Bear, H.D.3
  • 7
    • 24644490871 scopus 로고    scopus 로고
    • Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial
    • Smith IE, Dowsett M, Ebbs SR et al. Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial. J Clin Oncol 2005; 23: 5108-5116.
    • (2005) J Clin Oncol , vol.23 , pp. 5108-5116
    • Smith, I.E.1    Dowsett, M.2    Ebbs, S.R.3
  • 8
    • 33646371731 scopus 로고    scopus 로고
    • Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women in hormone-receptor positive breast cancer
    • Cataliotti L, Buzdar A, Noguchi S et al. Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women in hormone-receptor positive breast cancer. Cancer 2006; 106: 2095-2103.
    • (2006) Cancer , vol.106 , pp. 2095-2103
    • Cataliotti, L.1    Buzdar, A.2    Noguchi, S.3
  • 9
    • 0035692576 scopus 로고    scopus 로고
    • Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicentre study
    • Eiermann W, Paepke S, Appfelstaedt J et al. Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicentre study. Ann Oncol 2001; 12: 1527-1532.
    • (2001) Ann Oncol , vol.12 , pp. 1527-1532
    • Eiermann, W.1    Paepke, S.2    Appfelstaedt, J.3
  • 10
    • 3543008606 scopus 로고    scopus 로고
    • First line hormonal treatment for metastatic breast cancer with exemestane or tamoxifen in postmenopausal patients - a randomized phase III trial of the EORTC Breast Group
    • Abstr 515
    • Paridaens R, Therasse P, Dirix L et al. First line hormonal treatment for metastatic breast cancer with exemestane or tamoxifen in postmenopausal patients - a randomized phase III trial of the EORTC Breast Group. Proc Am Soc Clin Oncol 2004: 6 (Abstr 515).
    • (2004) Proc Am Soc Clin Oncol , pp. 6
    • Paridaens, R.1    Therasse, P.2    Dirix, L.3
  • 11
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes RC, Hall E, Gibson LJ et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004; 350: 1081-1092.
    • (2004) N Engl J Med , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 12
    • 0002098697 scopus 로고    scopus 로고
    • Exemestane as Neoadjuvant treatment for locally advanced breast cancer: Endocrinologic and clinical endpoints
    • Abstr 170
    • Dixon JM, Grattage L, Renshaw L et al. Exemestane as Neoadjuvant treatment for locally advanced breast cancer: Endocrinologic and clinical endpoints. Breast Cancer Res Treat 2000; 62: 53 (Abstr 170).
    • (2000) Breast Cancer Res Treat , vol.62 , pp. 53
    • Dixon, J.M.1    Grattage, L.2    Renshaw, L.3
  • 13
    • 33750853420 scopus 로고    scopus 로고
    • Exemestane as neoadjuvant treatment in patients > 65 years with T > 3 cm; preliminary results of a multicenter Spanish Phase II trial
    • Abstr 272
    • Gil M, Barnadas A, Cirera L et al. Exemestane as neoadjuvant treatment in patients > 65 years with T > 3 cm; preliminary results of a multicenter Spanish Phase II trial. Breast Cancer Res Treat 2004; 76 (Suppl 1): S76 (Abstr 272).
    • (2004) Breast Cancer Res Treat , vol.76 , Issue.SUPPL. 1
    • Gil, M.1    Barnadas, A.2    Cirera, L.3
  • 14
    • 52949128414 scopus 로고    scopus 로고
    • Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: A phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17)
    • Epub Dec 22
    • Mlineritsch B, Tausch C, Singer C et al. Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: A phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17). Breast Cancer Res Treat 2008; 112 (1): 203-213. Epub 2007 Dec 22.
    • (2007) Breast Cancer Res Treat 2008 , vol.112 , Issue.1 , pp. 203-213
    • Mlineritsch, B.1    Tausch, C.2    Singer, C.3
  • 15
    • 36549059551 scopus 로고    scopus 로고
    • Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03)
    • Takei H, Suemasu K, Inoue K et al. Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03). Breast Cancer Res Treat 2008; 107: 87-94.
    • (2008) Breast Cancer Res Treat , vol.107 , pp. 87-94
    • Takei, H.1    Suemasu, K.2    Inoue, K.3
  • 16
    • 33144482444 scopus 로고    scopus 로고
    • Exemestane vs tamoxifen as neoadjuvant endocrine therapy for postmenopausal women with ER+ breast cancer (T2N1-2, T3N0-1, T4N0M0)
    • Abstr 530
    • Semiglazov V, Kletsel A, Semiglazov V et al. Exemestane vs tamoxifen as neoadjuvant endocrine therapy for postmenopausal women with ER+ breast cancer (T2N1-2, T3N0-1, T4N0M0). Proc Am Soc Clin Oncol 2005; 23: 16S (Abstr 530).
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Semiglazov, V.1    Kletsel, A.2    Semiglazov, V.3
  • 17
    • 0025869592 scopus 로고
    • Breast cancer in elderly women: A cancer research campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone
    • Bates T, Riley DL, Fallowfield L, Baum M. Breast cancer in elderly women: A cancer research campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. Br J Surg 1991; 78: 591.
    • (1991) Br J Surg , vol.78 , pp. 591
    • Bates, T.1    Riley, D.L.2    Fallowfield, L.3    Baum, M.4
  • 18
    • 0036302614 scopus 로고    scopus 로고
    • Neoadjuvant tamoxifen for hormone-sensitive non-metastatic breast carcinomas in early postmenopausal women
    • Mauriac L, Debled M, Durand M et al. Neoadjuvant tamoxifen for hormone-sensitive non-metastatic breast carcinomas in early postmenopausal women. Ann Oncol 2002; 13: 293-298.
    • (2002) Ann Oncol , vol.13 , pp. 293-298
    • Mauriac, L.1    Debled, M.2    Durand, M.3
  • 19
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982; 5: 649-655.
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 20
    • 63549149489 scopus 로고    scopus 로고
    • Exemestane as primary treatment in hormonosensible early breast cancer of the elderly. Preliminary results of a phase II multicenter open Italian Study
    • Abstr 10689
    • Mustacchi G, Farris A, Barni S et al. Exemestane as primary treatment in hormonosensible early breast cancer of the elderly. Preliminary results of a phase II multicenter open Italian Study. Proc Am Soc Clin Oncol 2006: 18S (Abstr 10689).
    • (2006) Proc Am Soc Clin Oncol
    • Mustacchi, G.1    Farris, A.2    Barni, S.3
  • 21
    • 12144262989 scopus 로고    scopus 로고
    • A multi-center study of pre-operative treatment with letrozole for optimal duration of treatment in postmenopausal women with ER and/or PGR positive breast cancer
    • Abstr 321
    • Paepke S, Tulusan A, Kiesel L et al. A multi-center study of pre-operative treatment with letrozole for optimal duration of treatment in postmenopausal women with ER and/or PGR positive breast cancer. Proc Am Soc Clin Oncol 2003; 22: 80 (Abstr 321).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 80
    • Paepke, S.1    Tulusan, A.2    Kiesel, L.3
  • 22
    • 33645208799 scopus 로고    scopus 로고
    • Is there an optimal duration of neoadjuvant letrozole therapy?
    • Abstr 405
    • Renshaw L, Murray J, Young O et al. Is there an optimal duration of neoadjuvant letrozole therapy? Breast Cancer Res Treat 2004; 88 (Suppl 1): S36 (Abstr 405).
    • (2004) Breast Cancer Res Treat , vol.88 , Issue.SUPPL. 1
    • Renshaw, L.1    Murray, J.2    Young, O.3
  • 23
    • 19944429855 scopus 로고    scopus 로고
    • Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival
    • Dowsett M, Smith IE, Ebbs SR et al. Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival. Clin Cancer Res 2005; 11 (2 Pt 2): 951s-958s.
    • (2005) Clin Cancer Res , vol.11 , Issue.2 PART 2
    • Dowsett, M.1    Smith, I.E.2    Ebbs, S.R.3
  • 24
    • 33846965616 scopus 로고    scopus 로고
    • Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer
    • Dowsett M, Smith IE, Ebbs SR et al. Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. J Natl Cancer Inst 2007; 99: 167-170.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 167-170
    • Dowsett, M.1    Smith, I.E.2    Ebbs, S.R.3
  • 25
    • 58149255238 scopus 로고    scopus 로고
    • Do classical oestrogen markers predict for clinical response to endocrine therapy?
    • Miller WR. Do classical oestrogen markers predict for clinical response to endocrine therapy? Breast Cancer Res 2007; 9 (Suppl 2): S19.
    • (2007) Breast Cancer Res , vol.9 , Issue.SUPPL. 2
    • Miller, W.R.1
  • 26
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial
    • Ellis MJ, Coop A, Singh B et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial. J Clin Oncol 2001; 19: 3808-3816.
    • (2001) J Clin Oncol , vol.19 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 27
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. Lancet 2005; 365: 1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 28
    • 19944422061 scopus 로고    scopus 로고
    • Multigene assay to predict recurrence of tamoxifen-treated, node negative breast cancer
    • Paik S, Shak S, Tang G et al. Multigene assay to predict recurrence of tamoxifen-treated, node negative breast cancer. N Engl J Med 2004; 351: 2817-2826.
    • (2004) N Engl J Med , vol.351 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3
  • 29
    • 28044472321 scopus 로고    scopus 로고
    • Gene expression profiles of paraffinembedded core biopsy tissue predict response to chemotherapy in women with locally advanced breast cancer
    • Gianni L, Zambetti M, Clark K et al. Gene expression profiles of paraffinembedded core biopsy tissue predict response to chemotherapy in women with locally advanced breast cancer. J Clin Oncol 2005; 23: 7265-7277.
    • (2005) J Clin Oncol , vol.23 , pp. 7265-7277
    • Gianni, L.1    Zambetti, M.2    Clark, K.3
  • 30
    • 0024987463 scopus 로고
    • Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more
    • Bonadonna G, Veronesi U, Brambilla C et al. Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more. J Natl Cancer Inst 1990; 82: 1539-1545.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1539-1545
    • Bonadonna, G.1    Veronesi, U.2    Brambilla, C.3
  • 31
    • 0025910589 scopus 로고
    • Effects of primary chemotherapy in conservative treatment of breast cancer patients with operable tumors larger than 3 cm. Results of a randomized trial in a single centre
    • Mauriac L, Durand M, Avril A et al. Effects of primary chemotherapy in conservative treatment of breast cancer patients with operable tumors larger than 3 cm. Results of a randomized trial in a single centre. Ann Oncol 1991; 2: 347-354.
    • (1991) Ann Oncol , vol.2 , pp. 347-354
    • Mauriac, L.1    Durand, M.2    Avril, A.3
  • 32
    • 0033050164 scopus 로고    scopus 로고
    • Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy
    • Kuerer HM, Newman LA, Smith TL et al. Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy. J Clin Oncol 1999; 17: 460-469.
    • (1999) J Clin Oncol , vol.17 , pp. 460-469
    • Kuerer, H.M.1    Newman, L.A.2    Smith, T.L.3
  • 33
    • 0037087562 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy in breast cancer: Significantly enhanced response with docetaxel
    • Smith IC, Heys SD, Hutcheon AW et al. Neoadjuvant chemotherapy in breast cancer: Significantly enhanced response with docetaxel. J Clin Oncol 2002; 20: 1456-1466.
    • (2002) J Clin Oncol , vol.20 , pp. 1456-1466
    • Smith, I.C.1    Heys, S.D.2    Hutcheon, A.W.3
  • 34
    • 0642347622 scopus 로고    scopus 로고
    • The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27
    • Bear HD, Anderson S, Brown A et al. The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol 2003; 21: 4165-4174.
    • (2003) J Clin Oncol , vol.21 , pp. 4165-4174
    • Bear, H.D.1    Anderson, S.2    Brown, A.3
  • 35
    • 12344277756 scopus 로고    scopus 로고
    • Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer
    • Ring AE, Smith IE, Ashley S et al. Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. Br J Cancer 2004; 91: 2012-2017.
    • (2004) Br J Cancer , vol.91 , pp. 2012-2017
    • Ring, A.E.1    Smith, I.E.2    Ashley, S.3
  • 36
    • 63549129841 scopus 로고    scopus 로고
    • Is pathologic complete response related to level of hormonal receptor positivity in hormonal-sensitive breast cancer treated with anthracycline-based neo-adjuvant chemotherapy?
    • Abstr 4024
    • Petit T, Wilt M, Velten M et al. Is pathologic complete response related to level of hormonal receptor positivity in hormonal-sensitive breast cancer treated with anthracycline-based neo-adjuvant chemotherapy? Breast Cancer Res Treat 2007; 106 (Suppl 1): S174 (Abstr 4024).
    • (2007) Breast Cancer Res Treat , vol.106 , Issue.SUPPL. 1
    • Petit, T.1    Wilt, M.2    Velten, M.3
  • 37
    • 23844549918 scopus 로고    scopus 로고
    • Breast cancer molecular subtypes respond differently to preoperative chemotherapy
    • Rouzier R, Perou CM, Symmans WF et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res 2005; 15: 5678-5685.
    • (2005) Clin Cancer Res , vol.15 , pp. 5678-5685
    • Rouzier, R.1    Perou, C.M.2    Symmans, W.F.3
  • 38
    • 0031020395 scopus 로고    scopus 로고
    • Locally advanced breast cancer: Early results of a randomised trial of multimodal versus initial hormone therapy
    • Willsher PC, Robertson JFR, Chan SY et al. Locally advanced breast cancer: Early results of a randomised trial of multimodal versus initial hormone therapy. Eur J Cancer 1997; 33: 45-49.
    • (1997) Eur J Cancer , vol.33 , pp. 45-49
    • Willsher, P.C.1    Robertson, J.F.R.2    Chan, S.Y.3
  • 39
    • 13844304611 scopus 로고    scopus 로고
    • The relative efficacy of neoadjuvant endocrine therapy vs chemotherapy in postmenopausal women with ER-positive breast cancer
    • Semiglazov VF, Semiglazov VV, Ivanov V et al. The relative efficacy of neoadjuvant endocrine therapy vs chemotherapy in postmenopausal women with ER-positive breast cancer. Proc Am Soc Clin Oncol (Post-Meeting Edition) 2004; 22: 519.
    • (2004) Proc Am Soc Clin Oncol (Post-Meeting Edition) , vol.22 , pp. 519
    • Semiglazov, V.F.1    Semiglazov, V.V.2    Ivanov, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.