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Volumn 5, Issue 3, 2009, Pages

Positional information generated by spatially distributed signaling cascades

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; CHEMICAL ACTIVATION; ENZYME ACTIVITY; SPATIAL DISTRIBUTION;

EID: 63549090526     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000330     Document Type: Article
Times cited : (40)

References (45)
  • 3
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L, Karin M (2001) Mammalian MAP kinase signalling cascades. Nature 410: 37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 5
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24: 21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 6
    • 0344832766 scopus 로고
    • Superiority of Interconvertible Enzyme Cascades in Metabolic Regulation: Analysis of Monocyclic Systems
    • Stadtman ER, Chock PB (1977) Superiority of Interconvertible Enzyme Cascades in Metabolic Regulation: Analysis of Monocyclic Systems. Proc Natl Acad Sci 74: 2761-2765.
    • (1977) Proc Natl Acad Sci , vol.74 , pp. 2761-2765
    • Stadtman, E.R.1    Chock, P.B.2
  • 7
    • 0001424903 scopus 로고
    • An Amplified Sensitivity Arising from Covalent Modification in Biological Systems
    • Goldbeter A, Koshland DE (1981) An Amplified Sensitivity Arising from Covalent Modification in Biological Systems. Proc Natl Acad Sci 78: 6840-6844.
    • (1981) Proc Natl Acad Sci , vol.78 , pp. 6840-6844
    • Goldbeter, A.1    Koshland, D.E.2
  • 8
    • 0031203921 scopus 로고    scopus 로고
    • How responses get more switch-like as you move down a protein kinase cascade [letter; comment]
    • Ferrell JE Jr (1997) How responses get more switch-like as you move down a protein kinase cascade [letter; comment]. Trends Biochem Sci 22: 288-289.
    • (1997) Trends Biochem Sci , vol.22 , pp. 288-289
    • Ferrell Jr, J.E.1
  • 9
    • 0031559933 scopus 로고    scopus 로고
    • Kholodenko BN, Hoek JB, Westerhoff HV, Brown GC (1997) Quantification of information transfer via cellular signal transduction pathways [published erratum appears in FEBS Lett 1997 Dec 8;419(1):150]. FEBS Lett 414: 430-434.
    • Kholodenko BN, Hoek JB, Westerhoff HV, Brown GC (1997) Quantification of information transfer via cellular signal transduction pathways [published erratum appears in FEBS Lett 1997 Dec 8;419(1):150]. FEBS Lett 414: 430-434.
  • 10
    • 0034914737 scopus 로고    scopus 로고
    • A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (mapk) pathway model
    • Asthagiri AR, Lauffenburger DA (2001) A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (mapk) pathway model. Biotechnol Prog 17: 227-239.
    • (2001) Biotechnol Prog , vol.17 , pp. 227-239
    • Asthagiri, A.R.1    Lauffenburger, D.A.2
  • 11
    • 0034613112 scopus 로고    scopus 로고
    • Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells
    • In Process Citation
    • Brightman FA, Fell DA (2000) Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells [In Process Citation]. FEBS Lett 482: 169-174.
    • (2000) FEBS Lett , vol.482 , pp. 169-174
    • Brightman, F.A.1    Fell, D.A.2
  • 12
    • 0037047611 scopus 로고    scopus 로고
    • MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
    • Bhalla US, Ram PT, Iyengar R (2002) MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023.
    • (2002) Science , vol.297 , pp. 1018-1023
    • Bhalla, U.S.1    Ram, P.T.2    Iyengar, R.3
  • 13
    • 0345359924 scopus 로고    scopus 로고
    • A positive-feedback-based bistable 'memory module' that governs a cell fate decision
    • Xiong W, Ferrell JE Jr (2003) A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426: 460-465.
    • (2003) Nature , vol.426 , pp. 460-465
    • Xiong, W.1    Ferrell Jr, J.E.2
  • 14
    • 33644524741 scopus 로고    scopus 로고
    • Cell-signalling dynamics in time and space
    • Kholodenko BN (2006) Cell-signalling dynamics in time and space. Nat Rev Mol Cell Biol 7: 165-176.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 165-176
    • Kholodenko, B.N.1
  • 15
    • 42049116557 scopus 로고    scopus 로고
    • FGF induces oscillations of Hes1 expression and Ras/ERK activation
    • Nakayama K, Satoh T, Igari A, Kageyama R, Nishida E (2008) FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr Biol 18: R332-334.
    • (2008) Curr Biol , vol.18
    • Nakayama, K.1    Satoh, T.2    Igari, A.3    Kageyama, R.4    Nishida, E.5
  • 16
    • 34848893336 scopus 로고    scopus 로고
    • Bistability and oscillations in the Huang-Ferrell model of MAPK signaling
    • doi:10.1371/journal.pcbi.0030184
    • Qiao L, Nachbar RB, Kevrekidis IG, Shvartsman SY (2007) Bistability and oscillations in the Huang-Ferrell model of MAPK signaling. PLoS Comput Biol 3: 1819-1826. doi:10.1371/journal.pcbi.0030184.
    • (2007) PLoS Comput Biol , vol.3 , pp. 1819-1826
    • Qiao, L.1    Nachbar, R.B.2    Kevrekidis, I.G.3    Shvartsman, S.Y.4
  • 17
    • 0036285634 scopus 로고    scopus 로고
    • Mathematical models of protein kinase signal transduction
    • Heinrich R, Neel BG, Rapoport TA (2002) Mathematical models of protein kinase signal transduction. Mol Cell 9: 957-970.
    • (2002) Mol Cell , vol.9 , pp. 957-970
    • Heinrich, R.1    Neel, B.G.2    Rapoport, T.A.3
  • 18
    • 34547699211 scopus 로고    scopus 로고
    • Mathematical model for spatial segregation of the Rho-family GTPases based on inhibitory crosstalk
    • Jilkine A, Maree AF, Edelstein-Keshet L (2007) Mathematical model for spatial segregation of the Rho-family GTPases based on inhibitory crosstalk. Bull Math Biol 69: 1943-1978.
    • (2007) Bull Math Biol , vol.69 , pp. 1943-1978
    • Jilkine, A.1    Maree, A.F.2    Edelstein-Keshet, L.3
  • 20
    • 0038608273 scopus 로고    scopus 로고
    • Four-dimensional organization of protein kinase signaling cascades: The roles of diffusion, endocytosis and molecular motors
    • Kholodenko BN (2003) Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors. J Exp Biol 206: 2073-2082.
    • (2003) J Exp Biol , vol.206 , pp. 2073-2082
    • Kholodenko, B.N.1
  • 21
    • 0242690927 scopus 로고    scopus 로고
    • Control of spatially heterogeneous and time-varying cellular reaction networks: A new summation law
    • Peletier MA, Westerhoff HV, Kholodenko BN (2003) Control of spatially heterogeneous and time-varying cellular reaction networks: a new summation law. J Theor Biol 225: 477-487.
    • (2003) J Theor Biol , vol.225 , pp. 477-487
    • Peletier, M.A.1    Westerhoff, H.V.2    Kholodenko, B.N.3
  • 22
    • 14644404885 scopus 로고    scopus 로고
    • Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve
    • Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, et al. (2005) Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45: 715-726.
    • (2005) Neuron , vol.45 , pp. 715-726
    • Perlson, E.1    Hanz, S.2    Ben-Yaakov, K.3    Segal-Ruder, Y.4    Seger, R.5
  • 23
    • 33751116969 scopus 로고    scopus 로고
    • Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase
    • Perlson E, Michaelevski I, Kowalsman N, Ben-Yaakov K, Shaked M, et al. (2006) Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase. J Mol Biol 364: 938-944.
    • (2006) J Mol Biol , vol.364 , pp. 938-944
    • Perlson, E.1    Michaelevski, I.2    Kowalsman, N.3    Ben-Yaakov, K.4    Shaked, M.5
  • 24
    • 33750619877 scopus 로고    scopus 로고
    • Potential for Control of Signaling Pathways via Cell Size and Shape
    • Meyers J, Craig J, Odde DJ (2006) Potential for Control of Signaling Pathways via Cell Size and Shape. Curr Biol 16: 1685-1693.
    • (2006) Curr Biol , vol.16 , pp. 1685-1693
    • Meyers, J.1    Craig, J.2    Odde, D.J.3
  • 25
    • 35748929940 scopus 로고    scopus 로고
    • Enzyme localization can drastically affect signal amplification in signal transduction pathways
    • doi:10.1371/journal.pcbi.0030195
    • van Albada SB, ten Wolde PR (2007) Enzyme localization can drastically affect signal amplification in signal transduction pathways. PLoS Comput Biol 3: 1925-1934. doi:10.1371/journal.pcbi.0030195.
    • (2007) PLoS Comput Biol , vol.3 , pp. 1925-1934
    • van Albada, S.B.1    ten Wolde, P.R.2
  • 26
    • 43049156015 scopus 로고    scopus 로고
    • Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks
    • Neves SR, Tsokas P, Sarkar A, Grace EA, Rangamani P, et al. (2008) Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks. Cell 133: 666-680.
    • (2008) Cell , vol.133 , pp. 666-680
    • Neves, S.R.1    Tsokas, P.2    Sarkar, A.3    Grace, E.A.4    Rangamani, P.5
  • 27
    • 0032864252 scopus 로고    scopus 로고
    • Spatial gradients of cellular phosphoproteins
    • Brown GC, Kholodenko BN (1999) Spatial gradients of cellular phosphoproteins. FEBS Lett 457: 452-454.
    • (1999) FEBS Lett , vol.457 , pp. 452-454
    • Brown, G.C.1    Kholodenko, B.N.2
  • 28
    • 0037192461 scopus 로고    scopus 로고
    • Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
    • Kalab P, Weis K, Heald R (2002) Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science 295: 2452-2456.
    • (2002) Science , vol.295 , pp. 2452-2456
    • Kalab, P.1    Weis, K.2    Heald, R.3
  • 29
    • 1642322097 scopus 로고    scopus 로고
    • Stathmin-tubulin interaction gradients in motile and mitotic cells
    • Niethammer P, Bastiaens P, Karsenti E (2004) Stathmin-tubulin interaction gradients in motile and mitotic cells. Science 303: 1862-1866.
    • (2004) Science , vol.303 , pp. 1862-1866
    • Niethammer, P.1    Bastiaens, P.2    Karsenti, E.3
  • 30
    • 35748968807 scopus 로고    scopus 로고
    • Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling
    • Maeder CI, Hink MA, Kinkhabwala A, Mayr R, Bastiaens PI, et al. (2007) Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling. Nat Cell Biol 9: 1319-1326.
    • (2007) Nat Cell Biol , vol.9 , pp. 1319-1326
    • Maeder, C.I.1    Hink, M.A.2    Kinkhabwala, A.3    Mayr, R.4    Bastiaens, P.I.5
  • 31
    • 45749115811 scopus 로고    scopus 로고
    • Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient
    • Fuller BG, Lampson MA, Foley EA, Rosasco-Nitcher S, Le KV, et al. (2008) Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature 453: 1132-1136.
    • (2008) Nature , vol.453 , pp. 1132-1136
    • Fuller, B.G.1    Lampson, M.A.2    Foley, E.A.3    Rosasco-Nitcher, S.4    Le, K.V.5
  • 32
    • 0036536713 scopus 로고    scopus 로고
    • MAP kinase cascade signaling and endocytic trafficking: A marriage of convenience?
    • Kholodenko BN (2002) MAP kinase cascade signaling and endocytic trafficking: a marriage of convenience? Trends Cell Biol 12: 173-177.
    • (2002) Trends Cell Biol , vol.12 , pp. 173-177
    • Kholodenko, B.N.1
  • 33
    • 33846042014 scopus 로고    scopus 로고
    • Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades
    • Markevich NI, Tsyganov MA, Hoek JB, Kholodenko BN (2006) Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades. Mol Syst Biol 2: 61.
    • (2006) Mol Syst Biol , vol.2 , pp. 61
    • Markevich, N.I.1    Tsyganov, M.A.2    Hoek, J.B.3    Kholodenko, B.N.4
  • 35
    • 0026475293 scopus 로고
    • Control of the metabolic flux in a system with high enzyme concentrations and moiety-conserved cycles. The sum of the flux control coefficients can drop significantly below unity
    • Kholodenko BN, Lyubarev AE, Kurganov BI (1992) Control of the metabolic flux in a system with high enzyme concentrations and moiety-conserved cycles. The sum of the flux control coefficients can drop significantly below unity. Eur J Biochem 210: 147-153.
    • (1992) Eur J Biochem , vol.210 , pp. 147-153
    • Kholodenko, B.N.1    Lyubarev, A.E.2    Kurganov, B.I.3
  • 37
    • 23244442051 scopus 로고    scopus 로고
    • A molecular model for axon guidance based on cross talk between rho GTPases
    • Sakumura Y, Tsukada Y, Yamamoto N, Ishii S (2005) A molecular model for axon guidance based on cross talk between rho GTPases. Biophys J 89: 812-822.
    • (2005) Biophys J , vol.89 , pp. 812-822
    • Sakumura, Y.1    Tsukada, Y.2    Yamamoto, N.3    Ishii, S.4
  • 38
    • 34247619844 scopus 로고    scopus 로고
    • Fundamental limits to position determination by concentration gradients
    • doi:10.1371/journal.pcbi.0030078
    • Tostevin F, ten Wolde PR, Howard M (2007) Fundamental limits to position determination by concentration gradients. PLoS Comput Biol 3: e78. doi:10.1371/journal.pcbi.0030078.
    • (2007) PLoS Comput Biol , vol.3
    • Tostevin, F.1    ten Wolde, P.R.2    Howard, M.3
  • 39
    • 0034019315 scopus 로고    scopus 로고
    • Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
    • Kholodenko BN (2000) Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. Eur J Biochem 267: 1583-1588.
    • (2000) Eur J Biochem , vol.267 , pp. 1583-1588
    • Kholodenko, B.N.1
  • 40
    • 43649095122 scopus 로고    scopus 로고
    • Wave-pinning and cell polarity from a bistable reaction-diffusion system
    • Mori Y, Jilkine A, Edelstein-Keshet L (2008) Wave-pinning and cell polarity from a bistable reaction-diffusion system. Biophys J 94: 3684-3697.
    • (2008) Biophys J , vol.94 , pp. 3684-3697
    • Mori, Y.1    Jilkine, A.2    Edelstein-Keshet, L.3
  • 42
    • 0029163545 scopus 로고
    • A viable reaction-diffusion wave on the skin of Pomacanthus, the marine Angelfish
    • Kondo S, Asai R (1995) A viable reaction-diffusion wave on the skin of Pomacanthus, the marine Angelfish. Nature 376: 765-768.
    • (1995) Nature , vol.376 , pp. 765-768
    • Kondo, S.1    Asai, R.2
  • 43
    • 33845301220 scopus 로고    scopus 로고
    • WNT and DKK Determine Hair Follicle Spacing Through a Reaction-Diffusion Mechanism
    • Sick S, Reinker S, Timmer J, Schlake T (2006) WNT and DKK Determine Hair Follicle Spacing Through a Reaction-Diffusion Mechanism. Science 314: 1447-1450.
    • (2006) Science , vol.314 , pp. 1447-1450
    • Sick, S.1    Reinker, S.2    Timmer, J.3    Schlake, T.4
  • 44
    • 35148861119 scopus 로고    scopus 로고
    • Synthetic Turing protocells: Vesicle self-reproduction through symmetry-breaking instabilities
    • Macia J, Sole RV (2007) Synthetic Turing protocells: vesicle self-reproduction through symmetry-breaking instabilities. Philos Trans R Soc Lond B Biol Sci 362: 1821-1829.
    • (2007) Philos Trans R Soc Lond B Biol Sci , vol.362 , pp. 1821-1829
    • Macia, J.1    Sole, R.V.2
  • 45
    • 43049176242 scopus 로고    scopus 로고
    • Giving space to cell signaling
    • Kholodenko BN, Kolch W (2008) Giving space to cell signaling. Cell 133: 566-567.
    • (2008) Cell , vol.133 , pp. 566-567
    • Kholodenko, B.N.1    Kolch, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.