Close examination of steroidogenesis disorders in a DOC- and progesterone-producing adrenocortical carcinoma

Endocrine

Volumn 35, Issue 1, 2009, Pages 25-33

  Sone, Masakatsu ^a   Shibata, Hirotaka ^b   Homma, Keiko ^c   Tamura, Naohisa ^a   Akahira, Jun Ichi ^d   Hamada, Satoshi ^a   Yahata, Mitsuhiko ^a   Fukui, Nobuyuki ^a   Itoh, Hiroshi ^b   Sasano, Hironobu ^d   Nakao, Kazuwa ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KEIO UNIVERSITY HOSPITAL   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adrenocortical carcinoma; Amenorrhea; DOC; Hypertension; Hypokalemia; Steroid

Indexed keywords

17 HYDROXYPREGNENOLONE; 18 HYDROXYDEOXYCORTICOSTERONE; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; ANDROGEN; ANDROSTENEDIONE; CORTICOSTERONE; CORTODOXONE; DEOXYCORTICOSTERONE; HYDROCORTISONE; PRASTERONE; PREGNENOLONE; PROGESTERONE; RENIN; STEROID 11BETA MONOOXYGENASE; STEROID 17ALPHA MONOOXYGENASE; STEROID;

ADRENAL CORTEX CARCINOMA; ADRENAL INCIDENTALOMA; ADULT; ALDOSTERONE BLOOD LEVEL; AMENORRHEA; ARTICLE; CASE REPORT; ENZYME ACTIVITY; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPERTENSION; HYPOKALEMIA; IMMUNOHISTOCHEMISTRY; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; STEROID RELEASE; STEROIDOGENESIS; ADRENAL CORTEX TUMOR; BIOLOGICAL MODEL; BIOSYNTHESIS; ENDOCRINE DISEASE; INCIDENTAL FINDING; METABOLISM; PHYSICAL EXAMINATION;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL CARCINOMA; ADULT; DESOXYCORTICOSTERONE; ENDOCRINE SYSTEM DISEASES; FEMALE; HUMANS; HYPERTENSION; INCIDENTAL FINDINGS; MODELS, BIOLOGICAL; PHYSICAL EXAMINATION; PROGESTERONE; STEROIDS;

EID: 63449127028     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-008-9123-5     Document Type: Article

References (22)

1. RT Kloos MD Gross IR Francis M Korobkin B Shapiro 1995 Incidentally discovered adrenal masses Endocr. Rev. 16 4 460 484
2. R Fraser VH James J Landon WS Peart A Rawson CA Giles AM McKay 1968 Clinical and biochemical studies of a patient with a corticosterone-secreting adrenocortical tumour Lancet 2 7578 1116 1120
3. JD Powell-Jackson A Calin R Fraser R Grahame P Mason GA Missen PR Powell-Jackson A Wilson 1974 Excess deoxycorticosterone secretion from adrenocortical carcinoma Br. Med. J. 2 5909 32 33
4. K Kondo T Saruta I Saito R Yoshida H Maruyama S Matsuki 1976 Benign desoxycorticosterone-producing adrenal tumor JAMA 236 9 1042 1044
5. Y Takahashi J Ninomiya J Horiguchi H Shimizu M Sato Y Koibuchi T Yoshida M Yoshida D Takata H Odawara T Yokoe Y Iino Y Morishita M Mori 2002 Primary amenorrhea accompanied by adrenal adenoma: start of menarche soon after tumor resection Intern. Med. 41 11 972 976 (Pubitemid 35423080)
6. P van Zonneveld HP Koppeschaar TW de Bruin TM Vroom MA Blankenstein TJ van Vroonhoven 1995 A patient with a progesterone-producing adrenal adenoma who presented with primary amenorrhea Gynecol. Endocrinol. 9 3 189 194
7. K Homma T Hasegawa M Masumoto E Takeshita K Watanabe H Chiba T Kurosawa T Takahashi N Matsuo 2003 Reference values for urinary steroids in Japanese newborn infants: gas chromatography/mass spectrometry in selected ion monitoring Endocr. J. 50 783 792 (Pubitemid 38139964)
8. H Sasano T Suzuki H Nagura T Nishikawa 1993 Steroidogenesis in human adrenocortical carcinoma: biochemical activities, immunohistochemistry, and in situ hybridization of steroidogenic enzymes and histopathologic study in nine cases Hum. Pathol. 24 4 397 404 (Pubitemid 23127256)
9. A Sugawara K Takeuchi T Suzuki K Itoi H Sasano S Ito 2003 A case of aldosterone-producing adrenocortical adenoma associated with a probable post-operative adrenal crisis: histopathological analyses of the adrenal gland Hypertens. Res. 26 8 663 668 (Pubitemid 37080799)
10. MC Damasco F Diaz JP Anal CP Lantos 1979 Acute effects of three natural corticosteroids on the acid-base and electrolyte composition of urine in adrenalectomized rats Acta Physiol. Lat. Am. 29 305 (Pubitemid 11229996)
11. RL Rosenfield S Bickel AK Razdan 1980 Amenorrhea related to progestin excess in congenital adrenal hyperplasia Obstet. Gynecol. 56 2 208 215 (Pubitemid 10035781)
12. DJ Holmes-Walker GS Conway JW Honour G Rumsby HS Jacobs 1995 Menstrual disturbance and hypersecretion of progesterone in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency Clin. Endocrinol. (Oxf) 43 3 291 296
13. J Helleday B Siwers EM Ritzén K Carlström 1993 Subnormal androgen and elevated progesterone levels in women treated for congenital virilizing 21-hydroxylase deficiency J. Clin. Endocrinol. Metab. 76 4 933 936 (Pubitemid 23110841)
14. DJ Hemrika EH Slaats JC Kennedy TJ de Vriess Robles-Korsen J Schoemaker 1993 Pulsatile luteinizing hormone patterns in long term oral contraceptive users J. Clin. Endocrinol. Metab. 77 2 420 426 (Pubitemid 23230051)
15. Y Toyoda M Mizukoshi M Umemoto M Kuchii K Ueyama S Tomimoto A Baba H Shima I Nishio Y Masuyama 1996 Adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone Intern. Med. 35 2 123 128 (Pubitemid 126476965)
16. K Makino K Yasuda M Okuyama M Ojima N Sasano K Miura 1987 An adrenocortical tumor secreting weak mineralocorticoids Endocrinol. Jpn. 34 1 65 72
17. SE Ishikawa T Saito K Kaneko K Okada S Fukuda T Kuzuya 1988 Hypermineralocorticism without elevation of plasma aldosterone: deoxycorticosterone-producing adrenal adenoma and hyperplasia Clin. Endocrinol. (Oxf) 29 4 367 375 (Pubitemid 18239382)
18. WL Miller 2008 Steroidogenic enzymes. Review Endocr. Dev. 13 1 18
19. H Shibata Y Ikeda T Mukai K Morohashi I Kurihara T Ando T Suzuki S Kobayashi M Murai I Saito T Saruta 2001 Expression profiles of COUP-TF, DAX-1 and SF-1 in human adrenal gland and adrenocortical tumors: possible implications in steroidogenesis Mol. Genet. Metab. 74 206 216 (Pubitemid 32955161)
20. R.J. Auchus, The genetics, pathophysiology, and management of human deficiencies of P450c17. Review. Endocrinol. Metab. Clin. North Am. 30(1), 101-119, vii (2001)
21. T Ogishima H Shibata H Shimada F Mitani H Suzuki T Saruta Y Ishimura 1991 Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism J. Biol. Chem. 266 10731 10734 (Pubitemid 21906864)
22. H Shibata H Suzuki T Ogishima Y Ishimura T Saruta 1993 Significance of steroidogenic enzymes in the pathogenesis of adrenal tumor Acta Endocrinol. 128 235 242 (Pubitemid 23100880)