Timing issues in fracture management a review of current concepts

Bulletin of the NYU Hospital for Joint Diseases

Volumn 67, Issue 1, 2009, Pages 58-67

  Fulkerson, Eric W ^a,b   Egol, Kenneth A ^a,c  

^a NYU HOSPITAL FOR JOINT DISEASES   (United States)

^b Muir Orthopaedic Specialists   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT RESPIRATORY DISTRESS SYNDROME; FEMUR FRACTURE; FEMUR NECK FRACTURE; FOOT FRACTURE; FRACTURE FIXATION; GUNSHOT INJURY; HEALTH CARE PERSONNEL; HEMODYNAMICS; HUMAN; LUNG INJURY; MEDICAL CARE; MEDICAL LITERATURE; MEDICAL RESEARCH; MEDICAL SERVICE; MULTIPLE ORGAN FAILURE; NONHUMAN; OPEN FRACTURE; PATIENT CARE; PELVIS FRACTURE; REVIEW; SOFT TISSUE INJURY; TIBIA FRACTURE; WOUND CLOSURE;

ADULT; CALCANEUS; DEBRIDEMENT; DIAPHYSES; FEMALE; FEMORAL NECK FRACTURES; FRACTURE FIXATION; FRACTURES, BONE; HEMODYNAMICS; HUMANS; MALE; PATIENT CARE TEAM; PELVIC BONES; SURGICAL FLAPS; TIBIAL FRACTURES; TIME FACTORS; TREATMENT OUTCOME; WOUNDS, GUNSHOT; YOUNG ADULT;

EID: 63449113296     PISSN: 19369719     EISSN: 19369727     Source Type: Journal    
DOI: None     Document Type: Review

References (100)

1. Bergen G, Chen LH, Warner M, Fingerhut LA. Injury in the United States: 2007 Chartbook. Hyattsville, Maryland. National Center for Health Statistics, 2008.
2. Skaggs DL, Friend L, Alman B, et al. The effect of surgical delay on acute infection following 554 open fractures in children. J Bone Joint Surg Am. 2005;87:8-12.
3. Noumi T, Yokoyama K, Ohtsuka H, et al. Intramedullary nailing for open fractures of the femoral shaft: evaluation of contributing factors on deep infection and nonunion using multivariate analysis. Injury. 2005;36:1085-93.
4. Harley BJ, Beaupre LA, Jones CA, et al. The effect of time to definitive treatment on the rate of nonunion and infection in open fractures. J Orthop Trauma. 2002;16:484-90.
5. Benson DR, Riggins RS, Lawrence RM, et al. Treatment of open fractures: a prospective study. J Trauma. 1983;23:25-30.
6. Caudle RJ, Stern PJ. Severe open fractures of the tibia. J Bone Joint Surg Am. 1987;69:801-7.
7. Trentz O, Oestern HJ, Hempelmann G, et al.[Criteria for the operability of patients with multiple injuries(author's transl)]. Unfallheilkunde. 1978 Jun;81(6):451-8.
8. Shapiro MB, Jenkins DH, Schwab CW, Rotondo MR Damage control: collective review. J Trauma. 2000 Nov;49(5):969-78.
9. Burch JM, Ortiz VB, Richardson RJ, et al. Abbreviated laparotomy and planned reoperation for critically injured patients. Ann Surg. 1992 May;215(5):476-83; discussion 483-4.
10. Ferrara A, Mac Arthur JD, Wright HK, et al. Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion. Am J Surg. 1990 Nov;160(5):515-8.
11. Hauser CJ, Zhou X, Joshi P, et al. The immune microenviron- ment of human fracture/soft-tissue hematomas and its relationship to systemic immunity. J Trauma. 1997 May;42(5):895-903; discussion 903-4.
12. Pape HC, Giannoudis PV, Krettek C, Trentz O. Timing of fixation of major fractures in blunt polytrauma: role of conventional indicators in clinical decision making. J Orthop Trauma. 2005 Sep;19(8):551-62.
13. Rotondo MF, Schwab CW, McGonigal MD, et al. 'Damage control': an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35(3):375-82; discussion 382-3.
14. Hansen ST, Winquist RA. Closed intramedullary nailing of the femur. Kuntscher technique with reaming. Clin Orthop Relat Res. 1979(138):56-61.
15. Johnson KD, Cadambi A, Seibert GB. Incidence of adult respiratory distress syndrome in patients with multiple musculoskeletal injuries: effect of early operative stabilization of fractures. J Trauma. 1985 May;25(5):375-84.
16. Bone LB, Johnson KD, Weigelt J, Scheinberg R. Early versus delayed stabilization of femoral fractures. A prospective randomized study. J Bone Joint Surg Am. 1989 Mar;71(3):336-40.
17. Pape HC, Regel G, Tscherne H. Local and systemic effects of fat embolization after intramedullary reaming and its influence by cofactors. Tech Orthop. 1996;11:2.
18. Pape HC, Schmidt RE, Rice J, et al. Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden. Crit Care Med. 2000;28:3441-8.
19. Nowotarski PJ, Turen CH, Brumback RJ, Scarboro JM. Conversion of external fixation to intramedullary nailing for fractures of the shaft of the femur in multiply injured patients. J Bone Joint Surg Am. 2000 Jun;82(6):781-8.
20. Nau T, Aldrian S, Koenig F, Vécsei V. Fixation of femoral fractures in multiple-injury patients with combined chest and head injuries. ANZ J Surg. 2003;73(12): 1018-21.
21. Pape HC, Schmidt RE, Rice J. Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden. Crit Care Med. 2000 Oct;28(10):3441-8.
22. Pietropaoli JA, Rogers FB, Shackford SR, et al. The deleterious effects of intraoperative hypotension on outcome in patients with severe head injuries. J Trauma. 1992 Sep;33(3):403-7.
23. Abramson D, Scalea TM, Hitchcock R, et al. Lactate clearance and survival following injury. J Trauma. 1993;35:584-8.
24. Asensio JA, McDuffie L, Petrone P, et al. Reliable variables in the exsanguinated patient which indicate damage control and predict outcome. Am J Surg. 2001;182:743-51.
25. Moore FA, Moore EE, Sauaia A. Blood transfusion. An independent risk factor for postinjury multiple organ failure. Arch Surg. 1997;132:620-4.
26. Sauaia A, Moore FA, Moore EE, et al. Early predictors of postinjury multiple organ failure. Arch Surg. 1994;129:39-45.
27. Regel G, Lobenhoffer P, Tscherne H. Acute management of the polytrauma patient. In: Tscherne H, Regel G(eds): Polytrauma Management. New York: Springer, 1997, pp. 257-297.
28. Gentilello LM, Jurkovich GJ, Stark MS, et al. Is hypothermia in the victim of major trauma protective or harmful? A randomized, prospective study. Ann Surg. 1997;226:439-47.
29. Waydhas C, Nast-Kolb D, Trupka A, et al. Die Bedeutung des traumatisch-hämorrhagischen schocks und der thoraxverlet- zung fur die prognose nach polytrauma. Hefte Unfallheilkd. 1990;212:104-5.
30. Wojcik K, Gazdzik TS, Jaworski JM, et al. The influence of body injuries on bone union of femoral shaft fractures treated by different operative methods[Polish], Chir Narzadow Ruchu OrtopPol. 2004;69:19-22.
31. Anwar IA, Battistella FD, Neiman R, et al. Femur fractures and lung complications: a prospective randomized study of reaming. Clin Orthop Rel Res. 2004;(422):71-6.
32. Moore EE, Shackford SR, Pachter HL, et al. Organ injury scaling: spleen, liver and kidney. J Trauma. 1989;29:439.
33. Rutledge R, Hunt JP, Lenbtz CW, et al. A statewide, population-based time-series analysis of the increasing frequency of non-operative management of abdominal solid organ injury. Ann Surg. 1995;222:311-26.
34. Giannoudis PV, Pape HC. Damage control orthopaedics in unstable pelvic ring injuries. Injury. 2004;35:671-7.
35. Pelias ME, Townsend MC, Flancbaum L. Long bone fractures predispose to pulmonary dysfunction in blunt chest trauma despite early operative fixation. Surgery. 1992; 111:576-9.
36. Roumen RM, Hendrijks T, ven der Ven-Jongekrijk J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg. 1993;218:769-76.
37. Pape H, Stalp M, Griensven M, et al. Optimal timing for secondary surgery in polytrauma patients: an evaluation of 4314 serious-injury cases[German], Chirurg. 1999;70(1 1): 1287-93.
38. Pape HC, van Griensven M, Rice J, et al. Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers. J Trauma. 2001;50(6):989-1000.
39. Brenneman FD, Katyal D, Boulanger BR, et al. Long-term outcomes in open pelvic fractures. J Trauma. 1997;42(5):773-7.
40. Browner BD, Cole JD, Graham JM, et al. Delayed posterior internal fixation of unstable pelvic fractures. J Trauma. 1987;27(9):998-1006.
41. Ertel W, Keel M, Eid K, et al. Control of severe hemorrhage using C-clamp and pelvic packing in multiply injured patients with pelvic ring disruption. J Orthop Trauma. 2001; 15(7):468 - 74.
42. Heetveld MJ, Harris I, Schlaphoff G, Sugrue M. Guidelines for the management of haemodynamically unstable pelvic fracture patients. ANZ J Surg. 2004;74(7):520-9.
43. Rommens PM. Pelvic ring injuries: a challenge for the trauma surgeon. Acta Chir Belg. 1996;96(2):78-84.
44. Rommens PM, Hessmann MH. Staged reconstruction of pelvic: ring disruption: differences in morbidity, mortality, radiologic results, and functional outcomes between B1, B2/B3, and C-type lesions. J Orthop Trauma. 2002;16(2):92-8.
45. Tucker MC, Nork SE, Simonian PT, Routt Jr ML. Simple anterior pelvic external fixation. J Trauma. 2000;49(6):989-94.
46. Baker SP, O'Neill B, Haddon Jr W, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974; 14(3): 187-96.
47. Hanson PB, Milne JC, Chapman MW. Open fractures of the pelvis. Review of 43 cases. J Bone Joint Surg Br. 1991;73(2):325-9.
48. Jones AL, Powell JN, Kellam JF, et al. Open pelvic fractures. A multicenter retrospective analysis. Orthop Clin North Am. 1997;28(3):345-50.
49. Perry Jr JF. Pelvic open fractures. Clin Orthop Relat Res. 1980;(151):41-5.
50. Rieger H, Joosten U, Probst A, Joist A. Significance of score systems in open complex trauma of the pelvis[German], Zentralbl Chir. 1999; 124(11): 1004-10.
51. Rothenberger DA, Fischer RP, Strate RG, et al. The mortality associated with pelvic fractures. Surgery. 1978;84(3):356-61.
52. Goulet JA, Bray TJ. Complex acetabular fractures. Clin Orthop Relat Res. 1989;(240):9-20.
53. Tile M, Helfet DL, Kellam JF. Fractures of the Pelvis and Acetabulum(3rd ed). Philadelphia: Lippincott Williams & Wilkins, 2003, pp. 3-11.
54. Wright R, Barrett K, Christie MJ, Johnson KD. Acetabular fractures: long-term follow-up of open reduction and internal fixation. J Orthop Trauma. 1994;8(5):397-403.
55. Latenser BA, Gentilello LM, Tarver AA, et al. Improved outcome with early fixation of skeletally unstable pelvic fractures, J Trauma. 1991 ;31(1):28-31.
56. Connor GS, McGwin Jr G, MacLennan PA, et al. Early versus delayed fixation of pelvic ring fractures. Am Surg. 2003 ;69(12): 1019-23.
57. Matta JM, Tornetta III P. Internal fixation of unstable pelvic ring injuries. Clin Orthop Relat Res. 1996;(329): 129-40
58. Brueton RN. A review of 40 acetabular fractures: the importance of early surgery. Injury. 1993;24(3):171-4.
59. Johnson EE, Matta JM, Mast JW, Letournel E. Delayed reconstruction of acetabular fractures 21 -120 days following injury. Clin Orthop Relat Res. 1994;(305):20-30.
60. Starr A, Ortega G, Sanders, M, et al. Decreased mortality among pelvic fracture patients: the effect of a pelvic fracture management protocol emphasizing pelvic binders and early arteriography. Orthopaedic Trauma Association Annual Meeting; 2006; Paper #39.
61. Eastridge BJ, Starr A, Minei JP, et al. The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions. J Trauma. 2002 Sep;53(3):446-50; discussion 450-1.
62. Miller PR, Moore PS, Mansell E, et al. External fixation or arteriogram in bleeding pelvic fracture: initial therapy guided by markers of arterial hemorrhage. J Trauma. 2003 Mar;54(3):437- 43.
63. Cook RE, Keating JF, Gillespie I. The role of angiography in the management of haemorrhage from major fractures of the pelvis. J Bone Joint Surg Br. 2002 Mar;84(2): 178-82.
64. Starr AJ, Griffin DR, Reinert CM, et al. Pelvic ring disruptions: prediction of associated injuries, transfusion requirement, pelvic arteriography, complications, and mortality. J Orthop Trauma. 2002Sep;16(8);553-61.
65. Routt ML Jr, Nork SE, Mills WJ. High-energy pelvic ring disruptions. Orthop Clin North Am. 2002 Jan;33(1):59-72, viii.
66. Zamzam MM. Unstable pelvic ring injuries. Outcome and timing of surgical treatment by internal fixation. Saudi Med. J. 2004;25(11): 1670-4.
67. Goldstein A, Phillips T, Sclafani SJ, et al. Early open reduction and internal fixation of the disrupted pelvic ring. J Trauma. 1986;26(4):325-33.
68. Plaisier BR, Meldon SW, Super DM, Malangoni MA. Improved outcome after early fixation of acetabular fractures. Injury. 2000;31(2):81-4.
69. American College of Surgeons Committee on Trauma: Resources for Optimal Care of the Injured Patient. Available at http://www.facs.org/trauma/amend99. html. Accessed May 10, 2006.
70. Williams T, Meynell GG. Time dependence and count-dependence in microbial infection. Nature. 1967;214 473-5.
71. Pollak AN, Jones AL, Castillo RG, et al. Time to definitive treatment significantly influences incidence of infection after open high-energy lower-extremity trauma. Presented at the Annual Scientific Meeting of the Orthopaedic Trauma Association; October 9-11, 2003; Salt Lake City, Utah.
72. Kindsfater K, Jonassen EA. Osteomyelitis in grade II and grade I11 open tibia fractures with late debridement. J Orthop Trauma. 1995;9:121-7
73. Trueta J. Reflections on the past and present treatment of war wounds and fractures. Mil Med. 1976;141:255-8.
74. Hampton OP Jr. Basic principles in management of open fractures. JAMA. 1955;159:417-9.
75. Sanders R, Swiontkowski MF, Nunley JA II, Spiegel PG. The management of fractures with soft-tissue disruptions. Instr Course Lect. 1994;43:559-70.
76. Hope PG, Cole WG. Open fractures of the tibia in children. J Bone Joint Surg Br. 1992;74:546-53.
77. Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am. 1976;58:453-8.
78. Cullen MC, Roy DR, Crawford AH, et al. Open fracture of the tibia in children. J Bone Joint Surg Am. 1996;78:1039-47.
79. DeLong WG Jr, Born CT, Wei SY, et al. Aggressive treatment of 119 open fracture wounds. J Trauma. 1999;46:1049-54.
80. Patzakis MJ, Bains RS, Lee J, et al. Prospective, randomized, double-blind study comparing single-agent antibiotic therapy, ciprofloxacin, to combination antibiotic therapy in open fracture wounds. J Orthop Trauma. 2000;14:529-33.
81. Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plast Reconstr Surg. 1986;78:285-92.
82. Gopal S, Majumder S, Batchelor AG, et al. Fix and flap: the radical orthopaedic and plastic treatment of severe open fractures of the tibia. J Bone Joint Surg Br. 2000;82:959-66.
83. Ordog GJ, Wasserberger J, Balasubramaniam S. Shotgun wound ballistics. J Trauma. 1988;28:624-31.
84. Janzon B, See man T. Muscle devitalization in high-energy missile wounds, and its dependence on energy transfer. J Trauma. 1985;25:138-44.
85. Di Maio V JM. Gunshot Wounds: Practical Aspects of Firearms, Ballistics, and Forensic Techniques. Boca Raton, Florida: CRC Press, 1993.
86. Zawitz MW. Guns used in crime. Washington, DC: US Department of Justice: Bureau of Justice Statistics Selected Findings, publication NCJ-148201, 1995.
87. Molinari RW, Yang EC, Strauss E, Einhorn TA. Timing of internal fixation in low-velocity extremity gunshot fractures. Contemp Orthop. 1994;29:335-9.
88. Wright DG, Levin JS, Esterhai JL, Heppenstall RB. Immediate internal fixation of low-velocity gunshot-related femoral fractures. J Trauma. 1993;35:678-82.
89. Brien WW, Kuschner SH, Brien EW, Wiss DA. The management of gunshot wounds to the femur. Orthop Clin North Am. 1995;26:133-8.
90. Nowotarski P, Brumback RJ. Immediate interlocking nailing of fractures of the femur caused by low- to midvelocity gunshots. J Orthop Trauma. 1994;8:134-41.
91. Barr RJ, Mollan RAB. The orthopaedic consequences of civil disturbance in Northern Ireland. J Bone Joint Surg Br. 1989;71:739-44.
92. Deitch EA, Grimes WR. Experience with 112 shotgun wounds of the extremities. J Trauma. 1984;24:600-3.
93. Orosz GM, Magazine J, Hannan EL, et al. Association of timing of surgery for hip fracture and patient outcomes. JAMA. 2004;291:1738-43.
94. Jain R, Koo M, Kreder HJ, et al. Comparison of early and delayed fixation of subcapital hip fractures in patients sixty years of age or less. J Bone Joint Surg Am. 2002 Sep;84(9):1605-12.
95. Maruenda JI, Barrios C, Gomar-Sancho F. Intracapsular hip pressure after femoral neck fracture. Clin Orthop Rel Res. 1997;340:172-80.
96. Bhandari M, Zlowodzki M.Tornetta P III, et al. Intramedullary nailing following external fixation in femoral and tibial shaft fractures. J Orthop Trauma. 2005;19:140-4.
97. Nowatarski PJ, Turen CH, Brumback RJ, et al. Conversion of external fixation to intramedullary nailing for fractures of the shaft of the femur in multiply injured patients. J Bone Joint Surg Am. 2000;82:781-8.
98. Tscherne H, Oestern HJ. A new classification of soft-tissue damage in open and closed fractures. Unfallheilkunde. 1982;85(3):111-5.
99. Smith CS, Nork SE, Sangeorzan BJ. The extruded talus: results of reimplantation. J Bone Joint Surg Am. 2006 Nov;88(ll):2418-24.
100. Schuberth JM, Jennings MM. Reconstruction of the extruded talus with large allograft interfaces: a report of 3 Cases. J Foot Ankle Surg. 2008 Sep-Oct;47(5):476-82.