Bone marrow-derived dendritic cells pulsed with tumor lysates induce anti-tumor immunity against gastric cancer ex vivo

World Journal of Gastroenterology

Volumn 14, Issue 46, 2008, Pages 7127-7132

  Li, Yan Lin ^a   Wu, Yu Gang ^a   Wang, Yong Qing ^a   Li, Zhong ^a   Wang, Rong Chao ^a   Wang, Liang ^b   Zhang, Yan Yun ^c  

^a THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cytokine; Cytotoxic T lymphocyte; Dendritic cells; Gastric cancer; Immunotherapy

Indexed keywords

B7 ANTIGEN; CD11B ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; STEM CELL FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BONE MARROW; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CELL CULTURE; CELL ISOLATION; CELL LYSATE; CELL MATURATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; EX VIVO STUDY; FLUORESCENCE ACTIVATED CELL SORTING; FREEZE THAWING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MICROSCOPY; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; STOMACH CANCER; TUMOR CELL; TUMOR IMMUNITY;

EID: 63449088283     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.7127     Document Type: Article

References (24)

1. Gilboa E. DC-based cancer vaccines. J Clin Invest 2007; 117: 1195-1203
2. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252
3. Hohenberger P, Gretschel S. Gastric cancer. Lancet 2003; 362: 305-315
4. Guida F, Formisano G, Esposito D, Antonino A, Conte P, Bencivenga M, Persico M, Avallone U. [Gastric cancer: surgical treatment and prognostic score] Minerva Chir 2008; 63: 93-99
5. Liakakos T, Fatourou E. Stage-specific guided adjuvant treatment for gastric cancer. Ann Surg Oncol 2008; 15: 2622-2623
6. Ishigami S, Natsugoe S, Tokuda K, Nakajo A, Xiangming C, Iwashige H, Aridome K, Hokita S, Aikou T. Clinical impact of intratumoral natural killer cell and dendritic cell infiltration in gastric cancer. Cancer Lett 2000; 159: 103-108
7. Ishigami S, Natsugoe S, Uenosono Y, Hata Y, Nakajo A, Miyazono F, Matsumoto M, Hokita S, Aikou T. Infiltration of antitumor immunocytes into the sentinel node in gastric cancer. J Gastrointest Surg 2003; 7: 735-739
8. Galetto A, Contarini M, Sapino A, Cassoni P, Consalvo E, Forno S, Pezzi C, Barnaba V, Mussa A, Matera L. Ex vivo host response to gastrointestinal cancer cells presented by autologous dendritic cells. J Surg Res 2001; 100: 32-38
9. Wu Y, Wang L, Zhang Y. Dendritic cells as vectors for immunotherapy of tumor and its application for gastric cancer therapy. Cell Mol Immunol 2004; 1: 351-356
10. + bone marrow hematopoietic progenitor cells. Blood 1998; 92: 118-128
11. Zhang Y, Zhang YY, Ogata M, Chen P, Harada A, Hashimoto S, Matsushima K. Transforming growth factor-beta1 polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through a monocyte/macrophage differentiation pathway. Blood 1999; 93: 1208-1220
12. Zhang Y, Yoneyama H, Wang Y, Ishikawa S, Hashimoto S, Gao JL, Murphy P, Matsushima K. Mobilization of dendritic cell precursors into the circulation by administration of MIP-1alpha in mice. J Natl Cancer Inst 2004; 96: 201-209
13. Ullrich E, Ménard C, Flament C, Terme M, Mignot G, Bonmort M, Plumas J, Chaperot L, Chaput N, Zitvogel L. Dendritic cells and innate defense against tumor cells. Cytokine Growth Factor Rev 2008; 19: 79-92
14. Nouri-Shirazi M, Banchereau J, Fay J, Palucka K. Dendritic cell based tumor vaccines. Immunol Lett 2000; 74: 5-10
15. Liu Q, Shu X, Sun A, Sun Q, Zhang C, An H, Liu J, Cao X. Plant-derived small molecule albaconol suppresses LPS-triggered proinflammatory cytokine production and antigen presentation of dendritic cells by impairing NF-kappaB activation. Int Immunopharmacol 2008; 8: 1103-1111
16. Warren TL, Bhatia SK, Acosta AM, Dahle CE, Ratliff TL, Krieg AM, Weiner GJ. APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells. J Immunol 2000; 165: 6244-6251
17. Hartmann G, Battiany J, Poeck H, Wagner M, Kerkmann M, Lubenow N, Rothenfusser S, Endres S. Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells. Eur J Immunol 2003; 33: 1633-1641
18. Su B, Wang J, Wang X, Jin H, Zhao G, Ding Z, Kang Y, Wang B. The effects of IL-6 and TNF-alpha as molecular adjuvants on immune responses to FMDV and maturation of dendritic cells by DNA vaccination. Vaccine 2008; 26: 5111-5122
19. Gonzalez-Carmona MA, Lukacs-Kornek V, Timmerman A, Shabani S, Kornek M, Vogt A, Yildiz Y, Sievers E, Schmidt-Wolf IG, Caselmann WH, Sauerbruch T, Schmitz V. CD40ligand-expressing dendritic cells induce regression of hepatocellular carcinoma by activating innate and acquired immunity in vivo. Hepatology 2008; 48: 157-168
20. He XZ, Wang L, Zhang YY. An effective vaccine against colon cancer in mice: use of recombinant adenovirus interleukin-12 transduced dendritic cells. World J Gastroenterol 2008; 14: 532-540
21. Boes M, Cerny J, Massol R, Op den Brouw M, Kirchhausen T, Chen J, Ploegh HL. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature 2002; 418: 983-988
22. Jalili A. Dendritic cells and their role in cancer immunotherapy. Iran J Immunol 2007; 4: 127-144
23. Schnurr M, Galambos P, Scholz C, Then F, Dauer M, Endres S, Eigler A. Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines. Cancer Res 2001; 61: 6445-6450
24. Kono K, Takahashi A, Sugai H, Fujii H, Choudhury AR, Kiessling R, Matsumoto Y. Dendritic cells pulsed with HER-2/neu-derived peptides can induce specific T-cell responses in patients with gastric cancer. Clin Cancer Res 2002; 8: 3394-3400