-
1
-
-
15844382075
-
A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities
-
Hahn H, Christiansen J, Wicking C, et al. A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities. J Biol Chem 1996;271:12125-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 12125-12128
-
-
Hahn, H.1
Christiansen, J.2
Wicking, C.3
-
2
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson R, Rothman A, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science (Wash DC) 1996;272:1668-71.
-
(1996)
Science (Wash DC)
, vol.272
, pp. 1668-1671
-
-
Johnson, R.1
Rothman, A.2
Xie, J.3
-
3
-
-
0024468746
-
The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
-
Hooper J, Scott M. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 1989;59:751-65.
-
(1989)
Cell
, vol.59
, pp. 751-765
-
-
Hooper, J.1
Scott, M.2
-
4
-
-
0024440611
-
A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
-
Nakano Y, Guerrero I, Hidalgo A, et al. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature (Lond) 1989;341:508-13.
-
(1989)
Nature (Lond)
, vol.341
, pp. 508-513
-
-
Nakano, Y.1
Guerrero, I.2
Hidalgo, A.3
-
5
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ. Biochemical evidence that patched is the Hedgehog receptor. Nature (Lond) 1996;384:176-9.
-
(1996)
Nature (Lond)
, vol.384
, pp. 176-179
-
-
Marigo, V.1
Davey, R.A.2
Zuo, Y.3
Cunningham, J.M.4
Tabin, C.J.5
-
6
-
-
0011102935
-
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
-
Stone DM, Hynes M, Armanini M, et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature (Lond) 1996;384:129-34.
-
(1996)
Nature (Lond)
, vol.384
, pp. 129-134
-
-
Stone, D.M.1
Hynes, M.2
Armanini, M.3
-
7
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
Denef N, Neubuser D, Perez L, Cohen SM. Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell 2000;102:521-31.
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubuser, D.2
Perez, L.3
Cohen, S.M.4
-
8
-
-
0030990735
-
Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma
-
Unden AB, Zaphiropoulos PG, Bruce K, Toftgard R, Stahle-Backdahl M. Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma. Cancer Res 1997;57:2336-40.
-
(1997)
Cancer Res
, vol.57
, pp. 2336-2340
-
-
Unden, A.B.1
Zaphiropoulos, P.G.2
Bruce, K.3
Toftgard, R.4
Stahle-Backdahl, M.5
-
9
-
-
0030955557
-
Basal cell carcinomas in mice overexpressing sonic hedgehog
-
Oro AE, Higgins KM, Hu Z, et al. Basal cell carcinomas in mice overexpressing sonic hedgehog. Science (Wash DC) 1997;276:817-21.
-
(1997)
Science (Wash DC)
, vol.276
, pp. 817-821
-
-
Oro, A.E.1
Higgins, K.M.2
Hu, Z.3
-
11
-
-
0031837454
-
Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
-
Hahn H, Wojnowski L, Zimmer AM, et al. Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat Med 1998;4:619-22.
-
(1998)
Nat Med
, vol.4
, pp. 619-622
-
-
Hahn, H.1
Wojnowski, L.2
Zimmer, A.M.3
-
12
-
-
0034732878
-
UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients
-
Daya-Grosjean L, Sarasin A. UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients. Mutat Res 2000;450:193-9.
-
(2000)
Mutat Res
, vol.450
, pp. 193-199
-
-
Daya-Grosjean, L.1
Sarasin, A.2
-
13
-
-
0033609006
-
High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum
-
Bodak N, Queille S, Avril MF, et al. High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum. Proc Natl Acad Sci USA 1999;96:5117-22.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5117-5122
-
-
Bodak, N.1
Queille, S.2
Avril, M.F.3
-
14
-
-
0021616838
-
UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
-
Maltzman W, Czyzyk L. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol 1984;4:1689-94.
-
(1984)
Mol Cell Biol
, vol.4
, pp. 1689-1694
-
-
Maltzman, W.1
Czyzyk, L.2
-
15
-
-
0031569350
-
Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro
-
Bernerd F, Asselineau D. Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro. Dev Biol 1997;183:123-38.
-
(1997)
Dev Biol
, vol.183
, pp. 123-138
-
-
Bernerd, F.1
Asselineau, D.2
-
16
-
-
0016729431
-
Serial cultivation of strains of human epidermal keralinocytes: The formation of keratinizing colonies from single cells
-
Rheinwald JG, Green H. Serial cultivation of strains of human epidermal keralinocytes: the formation of keratinizing colonies from single cells. Cell 1975;6:331-44.
-
(1975)
Cell
, vol.6
, pp. 331-344
-
-
Rheinwald, J.G.1
Green, H.2
-
17
-
-
85047700485
-
Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis
-
Hochedlinger K, Wagner E, Sabapathy K. Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis. Oncogene 2002;21:2441-5.
-
(2002)
Oncogene
, vol.21
, pp. 2441-2445
-
-
Hochedlinger, K.1
Wagner, E.2
Sabapathy, K.3
-
18
-
-
0033638970
-
NEMO/IKK γ-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian M, Bloch W, Courtois G, et al. NEMO/IKK γ-deficient mice model incontinentia pigmenti. Mol Cell 2000;5:981-92.
-
(2000)
Mol Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
Bloch, W.2
Courtois, G.3
-
19
-
-
0029874147
-
Cell survival and shuttle vector mutagenesis induced by ultraviolet A and ultraviolet B radiation in a human cell line
-
Robert C, Muel B, Benoit A, et al. Cell survival and shuttle vector mutagenesis induced by ultraviolet A and ultraviolet B radiation in a human cell line. J Investig Dermatol 1996;106:721-8.
-
(1996)
J Investig Dermatol
, vol.106
, pp. 721-728
-
-
Robert, C.1
Muel, B.2
Benoit, A.3
-
20
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
21
-
-
0001466654
-
GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization
-
Shin S, Kogerman P, Lindstrom E, Toftgard R, Biesecker L. GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization. Proc Natl Acad Sci USA 1999;96:2880-4.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2880-2884
-
-
Shin, S.1
Kogerman, P.2
Lindstrom, E.3
Toftgard, R.4
Biesecker, L.5
-
23
-
-
17644439060
-
Genetic correction of DNA repair deficient/cancer prone xeroderma pigmentosum group C keratinocytes
-
Arnaudeau-Bégard C, Brellier F, Chevallier-Lagente O, et al. Genetic correction of DNA repair deficient/cancer prone xeroderma pigmentosum group C keratinocytes. Hum Gene Ther 2003;14:983-96.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 983-996
-
-
Arnaudeau-Bégard, C.1
Brellier, F.2
Chevallier-Lagente, O.3
-
24
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 1993;7:2135-48.
-
(1993)
Genes Dev
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
25
-
-
0035830885
-
Role of IKKγ/nemo in assembly of the IκB kinase complex
-
Li X, Fang X, Gaynor R. Role of IKKγ/nemo in assembly of the IκB kinase complex. J Biol Chem 2001;276:4494-500.
-
(2001)
J Biol Chem
, vol.276
, pp. 4494-4500
-
-
Li, X.1
Fang, X.2
Gaynor, R.3
-
27
-
-
0029841366
-
Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: Different in vivo mechanisms of PTCH inactivation
-
Unden AB, Holmberg E, Lundh-Rozell B, et al. Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation. Cancer Res 1996;56:4562-5.
-
(1996)
Cancer Res
, vol.56
, pp. 4562-4565
-
-
Unden, A.B.1
Holmberg, E.2
Lundh-Rozell, B.3
-
28
-
-
0033523759
-
Sonic hedgehog opposes epithelial cell cycle arrest
-
Fan H, Khavari PA. Sonic hedgehog opposes epithelial cell cycle arrest. J Cell Biol 1999;147:71-6.
-
(1999)
J Cell Biol
, vol.147
, pp. 71-76
-
-
Fan, H.1
Khavari, P.A.2
-
29
-
-
0026341905
-
Rapid and preferential activation of the c-jun gene during the mammalian UV response
-
Devary Y, Gottlieb R, Lau L, Karin M. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol 1991;11:2804-11.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 2804-2811
-
-
Devary, Y.1
Gottlieb, R.2
Lau, L.3
Karin, M.4
-
30
-
-
0033569918
-
Stress-induced JNK activation is independent of Gadd45 induction
-
Shaulian E, Karin M. Stress-induced JNK activation is independent of Gadd45 induction. J Biol Chem 1999;274:29595-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 29595-29598
-
-
Shaulian, E.1
Karin, M.2
-
31
-
-
0025720735
-
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
-
Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1991;1072:129-57.
-
(1991)
Biochim Biophys Acta
, vol.1072
, pp. 129-157
-
-
Angel, P.1
Karin, M.2
-
32
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53 dependent
-
Schreiber M, Kolbus A, Piu F, et al. Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev 1999;13:607-19.
-
(1999)
Genes Dev
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
Kolbus, A.2
Piu, F.3
-
33
-
-
0024815627
-
Jun-B differs in its biological properties from, and is a negative regulator of c-Jun
-
Chiu R, Angel P, Karin M. Jun-B differs in its biological properties from, and is a negative regulator of c-Jun. Cell 1989;59:979-86.
-
(1989)
Cell
, vol.59
, pp. 979-986
-
-
Chiu, R.1
Angel, P.2
Karin, M.3
-
34
-
-
0025014995
-
Jun and Fos contribute to transcription activation by the heterodimer
-
Hirai S, Bourachot B, Yaniv M. Jun and Fos contribute to transcription activation by the heterodimer. Oncogene 1990;5:39-46.
-
(1990)
Oncogene
, vol.5
, pp. 39-46
-
-
Hirai, S.1
Bourachot, B.2
Yaniv, M.3
-
35
-
-
0030606319
-
c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions
-
Kallunki T, Deng T, Hibi M, Karin M. c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 1996;87:929-39.
-
(1996)
Cell
, vol.87
, pp. 929-939
-
-
Kallunki, T.1
Deng, T.2
Hibi, M.3
Karin, M.4
-
36
-
-
0029827366
-
The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light
-
Price M, Cruzalegui F, Treisman R. The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J 1996;15:6552-63.
-
(1996)
EMBO J
, vol.15
, pp. 6552-6563
-
-
Price, M.1
Cruzalegui, F.2
Treisman, R.3
-
37
-
-
0036134934
-
Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently
-
Young M, Nair R, Bucheimer N, et al. Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. Mol Cell Biol 2002;22:587-98.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 587-598
-
-
Young, M.1
Nair, R.2
Bucheimer, N.3
-
38
-
-
0035341310
-
Patched1 interacts with cyclin B1 to regulate cell cycle progression
-
Barnes E, Kong M, Ollendorff V, Donoghue D. Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J 2001;20:2214-23.
-
(2001)
EMBO J
, vol.20
, pp. 2214-2223
-
-
Barnes, E.1
Kong, M.2
Ollendorff, V.3
Donoghue, D.4
-
39
-
-
0032525308
-
Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint
-
Toyoshima F, Moriguchi T, Wada A, Fukuda M, Nishida E. Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint. EMBO J 1998;17:2728-35.
-
(1998)
EMBO J
, vol.17
, pp. 2728-2735
-
-
Toyoshima, F.1
Moriguchi, T.2
Wada, A.3
Fukuda, M.4
Nishida, E.5
-
40
-
-
0025997633
-
C-fos and c-jun proto-oncogene expression is decreased in psoriasis: An in situ quantitative analysis
-
Basset-Seguin N, Escot C, Moles J, et al. C-fos and c-jun proto-oncogene expression is decreased in psoriasis: an in situ quantitative analysis. J Investig Dermatol 1991;97:672-8.
-
(1991)
J Investig Dermatol
, vol.97
, pp. 672-678
-
-
Basset-Seguin, N.1
Escot, C.2
Moles, J.3
-
41
-
-
0028130085
-
Transcriptional regulation of human transglutaminase1 gene by signaling systems of protein kinase C, RAR/RXR and Jun/Fos in keratinocytes
-
Yamada K, Yamanishi K, Kakizuka A, et al. Transcriptional regulation of human transglutaminase1 gene by signaling systems of protein kinase C, RAR/RXR and Jun/Fos in keratinocytes. Biochem Mol Biol Int 1994;34:827-36.
-
(1994)
Biochem Mol Biol Int
, vol.34
, pp. 827-836
-
-
Yamada, K.1
Yamanishi, K.2
Kakizuka, A.3
-
42
-
-
0028905068
-
The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression
-
DiSepio D, Jones A, Longley M, et al. The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression. J Biol Chem 1995;270:10792-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 10792-10799
-
-
DiSepio, D.1
Jones, A.2
Longley, M.3
-
43
-
-
0027728548
-
Expression of the carcinoma-associated keratin K6 and the role of AP-1 proto-oncoproteins
-
Bernerd F, Magnaldo T, Freedberg IM, Blumenberg M. Expression of the carcinoma-associated keratin K6 and the role of AP-1 proto-oncoproteins. Gene Expr 1993;3:187-99.
-
(1993)
Gene Expr
, vol.3
, pp. 187-199
-
-
Bernerd, F.1
Magnaldo, T.2
Freedberg, I.M.3
Blumenberg, M.4
-
44
-
-
0037217819
-
TP53 mutations in human skin cancer
-
Giglia-Mari G, Sarasin A. TP53 mutations in human skin cancer. Hum Mutat 2003;21:217-28.
-
(2003)
Hum Mutat
, vol.21
, pp. 217-228
-
-
Giglia-Mari, G.1
Sarasin, A.2
-
45
-
-
0035900919
-
Induction of p53 expression in skin by radiotherapy and UV radiation: A randomized study
-
Ponten F, Lindman H, Bostrom A, Berne B, Bergh J. Induction of p53 expression in skin by radiotherapy and UV radiation: a randomized study. J Natl Cancer Inst (Bethesda) 2001;93:128-33.
-
(2001)
J Natl Cancer Inst (Bethesda)
, vol.93
, pp. 128-133
-
-
Ponten, F.1
Lindman, H.2
Bostrom, A.3
Berne, B.4
Bergh, J.5
-
46
-
-
0033638915
-
The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest
-
Shaulian E, Schreiber M, Piu F, et al. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 2000;103:897-907.
-
(2000)
Cell
, vol.103
, pp. 897-907
-
-
Shaulian, E.1
Schreiber, M.2
Piu, F.3
-
47
-
-
12844276949
-
Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident
-
Wicking C, Shanley S, Smyth I, et al. Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. Am J Hum Genet 1997;60:21-6.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 21-26
-
-
Wicking, C.1
Shanley, S.2
Smyth, I.3
-
48
-
-
0023222358
-
Nevoid basal-cell carcinoma syndrome
-
Gorlin R. Nevoid basal-cell carcinoma syndrome. Medicine (Baltimore) 1987;66:98-113.
-
(1987)
Medicine (Baltimore)
, vol.66
, pp. 98-113
-
-
Gorlin, R.1
-
49
-
-
0028079661
-
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells
-
Dong Z, Birrer M, Watts R, Matrisian L, Colburn N. Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci USA 1994;91:609-13.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 609-613
-
-
Dong, Z.1
Birrer, M.2
Watts, R.3
Matrisian, L.4
Colburn, N.5
|