Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/merlin

Experimental Biology and Medicine

Volumn 234, Issue 3, 2009, Pages 255-262

  Seo, Pil Soo ^a   Quinn, Brendan J ^a   Khan, Anwar A ^a   Zeng, Lixiao ^a,b   Takoudis, Christos G ^b   Hanada, Toshihiko ^a   Bolis, Annalisa ^c,d   Bolino, Alessandra ^c,d   Chishti, Athar H ^a,b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c DIBIT   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Erythrocyte p55; Ferm domain; Maguk; Merlin; MPP1; NF2; Protein 4.1r; Schwannomin

Indexed keywords

MERLIN; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; PROTEIN P55; MEMBRANE PROTEIN; MPP1 PROTEIN, HUMAN; PLASMA PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SCHWANN CELL; ANIMAL; BIOSYNTHESIS; CHEMISTRY; IMMUNOHISTOCHEMISTRY; METABOLISM; MYELIN SHEATH; NERVE CELL; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RAT; SURFACE PLASMON RESONANCE;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MYELIN SHEATH; NEUROFIBROMIN 2; NEURONS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; SCHWANN CELLS; SURFACE PLASMON RESONANCE;

EID: 63349099683     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0809-RM-275     Document Type: Article

References (27)

1. Lutchman M. Rouleau GA. Neurofibromatosis type 2: a new mechanism of tumor suppression. Trends Neurosci 19:373-377 1996. [CrossRef][Medline]
2. Martuza RL. Eldridge R. Neurofibromatosis 2 (bilateral acoustic neurofibromatosis). N Engl J Med 318:684-688, 1988. [Medline]
3. Rubio MP. Correa KM. Ramesh V. MacCollin MM. Jacoby LB. von Deimling A. Gusella JF. Louis DN. Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas. Cancer Res 54:45-47, 1994. [Abstract/Free Full Text]
4. Rouleau GA. Merel P. Lutchman M. Sanson M. Zucman J. Marineau C. Hoang-Xuan K. Demczuk S. Desmaze C. Plougastel B. et al. Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature 363:515-521, 1993. [CrossRef][Medline]
5. Trofatter JA. MacCollin MM. Rutter JL. Murrell JR. Duyao MP. Parry DM. Eldridge R. Kley N. Menon AG. Pulaski K. et al. A novel moesin-, ezrin-, radixin-like gene is a candidate for the neuro-fibromatosis 2 tumor suppressor. Cell 75:, 1993. [CrossRef][Medline]
6. Bretscher A. Edwards K. Fehon RG. ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 3:586-599, 2002. [CrossRef][Medline]
7. Scoles DR. The merlin interacting proteins reveal multiple targets for NF2 therapy. Biochim Biophys Acta 1785:32-54, 2008. [Medline]
8. Jindal HK. Yoshinaga K. Seo PS. Lutchman M. Dion PA. Rouleau GA. Hanada T. Chishti AH. Purification of the NF2 tumor suppressor protein from human erythrocytes. Can J Neurol Sci 33:394-402, 2006. [Medline]
9. Chishti AH. Function of p55 and its nonerythroid homologues. Curr Opin Hematol 5:116-121, 1998. [Medline]
10. Marfatia SM. Lue RA. Branton D. Chishti AH. Identification of the protein 4.1 binding interface on glycophorin C and p55, a homologue of the Drosophila discs-large tumor suppressor protein. J Biol Chem 270:715-719, 1995. [Abstract/Free Full Text]
11. Marfatia SM. Lue RA. Branton D. Chishti AH. In vitro binding studies suggest a membraneassociated complex between erythroid p55, protein 4.1, and glycophorin C. J Biol Chem 269:8631-8634, 1994. [Abstract/Free Full Text]
12. Jannatipour M. Dion P. Khan S. Jindal H. Fan X. Laganiere J. Chishti AH. Rouleau GA. Schwannomin isoform-1 interacts with syntenin via PDZ domains. J Biol Chem 276:33093-33100, 2001. [Abstract/Free Full Text]
13. Kim AC. Metzenberg AB. Sahr KE. Marfatia SM. Chishti AH. Complete genomic organization of the human erythroid p55 gene (MPP1), a membrane-associated guanylate kinase homologue. Genomics 31:223-229, 1996. [CrossRef][Medline]
14. Cole BK. Curto M. Chan AW. McClatchey AI. Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing. Mol Cell Biol 28:1274-1284, 2008. [Abstract/Free Full Text]
15. Previtali SC. Zerega B. Sherman DL. Brophy PJ. Dina G. King RH. Salih MM. Feltri L. Quattrini A. Ravazzolo R. Wrabetz L. Monaco AP. Bolino A. Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve. Hum Mol Genet 12:1713-1723, 2003. [Abstract/Free Full Text]
16. Bolino A. Bolis A. Previtali SC. Dina G. Bussini S. Dati G. Amadio S. Del Carro U. Mruk DD. Feltri ML. Cheng CY. Quattrini A. Wrabetz L. Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis. J Cell Biol 167:711-721, 2004. [Abstract/Free Full Text]
17. Nourry C. Grant SG. Borg JP. PDZ domain proteins: plug and play Sci STKE 2003: RE7, 2003. [Medline]
18. Kim E. Sheng M. PDZ domain proteins of synapses. Nat Rev Neurosci 5:771-781, 2004. [CrossRef][Medline]
19. Denisenko-Nehrbass N. Goutebroze L. Galvez T. Bonnon C. Stankoff B. Ezan P. Giovannini M. Faivre-Sarrailh C. Girault JA. Association of Caspr/paranodin with tumour suppressor schwannomin/merlin and beta1 integrin in the central nervous system. J Neurochem 84:209-221, 2003. [CrossRef][Medline]
20. Scoles DR. Huynh DP. Morcos PA. Coulsell ER. Robinson NG. Tamanoi F. Pulst SM. Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin. Nat Genet 18:354-359, 1998. [CrossRef][Medline]
21. Woods DF. Bryant PJ. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell 66:451-464, 1991. [CrossRef][Medline]
22. Ruff P. Speicher DW. Chishti A. Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif. Proc Natl Acad Sci U S A 88:6595-6599, 1991. [Abstract/Free Full Text]
23. Hung AY. Sheng M. PDZ domains: structural modules for protein complex assembly. J Biol Chem 277:5699-5702, 2002. [Free Full Text]
24. Alloisio N. Dalla Venezia N. Rana A. Andrabi K. Texier P. Gilsanz F. Cartron JP. Delaunay J. Chishti AH. Evidence that red blood cell protein p55 may participate in the skeleton-membrane linkage that involves protein 4.1 and glycophorin C. Blood 82:1323-1327, 1993. [Abstract/Free Full Text]
25. Bilder D. Schober M. Perrimon N. Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat Cell Biol 5:53-58, 2003. [CrossRef][Medline]
26. Mburu P. Kikkawa Y. Townsend S. Romero R. Yonekawa H. Brown SD. Whirlin complexes with p55 at the stereocilia tip during hair cell development. Proc Natl Acad Sci U S A 103:10973-10978, 2006. [Abstract/Free Full Text]
27. Gosens I. van Wijk E. Kersten FF. Krieger E. van der Zwaag B. Marker T. Letteboer SJ. Dusseljee S. Peters T. Spierenburg HA. Punte IM. Wolfrum U. Cremers FP. Kremer H. Roepman R. MPP1 links the Usher protein network and the Crumbs protein complex in the retina. Hum Mol Genet 16:1993-2003, 2007. [Abstract/Free Full Text]