NMDA antagonist and antipsychotic actions in cortico-subcortical circuits

Neurotoxicity Research

Volumn 14, Issue 2-3, 2008, Pages 129-140

  Kargieman, Lucila ^a   Santana, Noemí ^a   Mengod, Guadalupe ^b   Celada, Pau ^a   Artigas, Francesc ^a  

^a CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Antipsychotics; GABAergicinterneurons; Glutamate; NMD Areceptors; Oscillations; Prefrontalcortex; Pyramidal neurons; Thalamus

Indexed keywords

CLOZAPINE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; HALOPERIDOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT; PHENCYCLIDINE; PROTEIN C FOS; SODIUM CHLORIDE; VESICULAR GLUTAMATE TRANSPORTER 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE EXACERBATION; IN SITU HYBRIDIZATION; MALE; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; SCHIZOPHRENIA; THALAMOCORTICAL TRACT; THALAMUS NUCLEUS; TRANQUILIZING ACTIVITY; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NERVE TRACT; PHYSIOLOGY; SOMATOSENSORY CORTEX; WISTAR RAT;

ANIMALIA;

ANIMALS; ANTIPSYCHOTIC AGENTS; CEREBRAL CORTEX; CLOZAPINE; HALOPERIDOL; MALE; NEURAL PATHWAYS; PHENCYCLIDINE; PREFRONTAL CORTEX; PROTO-ONCOGENE PROTEINS C-FOS; PYRAMIDAL CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SOMATOSENSORY CORTEX; THALAMIC NUCLEI;

EID: 63249109494     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03033805     Document Type: Article

References (54)

1. Adams B and B Moghaddam (1998) Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine. J. Neurosci. 18, 5545-5554.
2. Adams BW and B Moghaddam (2001) Effect of clozapine, haloperidol or M1 00907 on phencyclidine-activated glutamate efflux in the prefrontal cortex. Biol. Psychiatry 50, 750-757.
3. Amargós-Bosch M, X López-Gil, F Artigas and A Adell (2006) Clozapine and olanzapine, but not haloperidol, suppress serotonin efflux in the medial prefrontal cortex elicited by phencyclidine and ketamine. Int. J. Neuropsychopharmacol. 9, 565-573.
4. Berendse HW and HJ Groenewegen (1991) Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat. Neuroscience 42, 73-102.
5. Breier A, AK Malhotra, DA Pinals, NI Weisenfeld and D Pickar (1997) Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers. Am. J. Psychiatry 154, 805-811.
6. Celada P, MV Puig, L Díaz-Mataix and F Artigas (2008) The hallucinogen DOI reduces low-frequency oscillations in rat prefrontal cortex: Reversal by antipsychotic drugs. Biol. Psychiatry 2008 Apr 22. [Epub ahead of print].
7. Dégenètais E, AM Thierry, J Glowinski and Y Gioanni (2002) Electrophysiological properties of pyramidal neurons in the rat prefrontal cortex: An in vivo intracellular recording study. Cereb. Cortex 12, 1-16.
8. Fuster JM (1997) The Prefrontal Cortex Anatomy, Physiology and Neuropsychology of the Frontal Lobe (Lipincott Raven:PHiladelphia/New York).
9. Geyer MA, K Krebs-Thomson, DL Braff and NR Swerdlow (2001) Pharmacological studies of prepulse inhibition mod els of sensorimotor gating deficits in schizophrenia: A decade in review. Psychopharmacology (Berl.) 156, 17-154.
10. Goto Y and AA Grace (2006) Alterations in medial prefrontal cortical activity and plasticity in rats with disruption of cortical development. Biol. Psychiatry 60, 1259-1267.
11. Groenewegen HJ and HB Uylings (2000) The prefrontal cortex and the integration of sensory limbic and autonomic information. Prog. Brain Res. 126, 3-28.
12. Hajos M (2006) Targeting information-processing deficit in schizophrenia: A novel approach to psychotherapeutic drug discovery. Trends Pharmacol. Sci. 27, 391-398.
13. Harrison PJ (1999) The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122, 593-624.
14. Hoffmann R, W Hendrickse, AJ Rush and R Armitage (2000) Slow-wave activity during non-REM sleep in men with schizophrenia and major depressive disorders. Psychiatry Res. 95, 215-225.
15. Jackson ME, H Homayoun and B Moghaddam (2004) NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc. Natl. Acad. Sci. USA 101, 8467-8472.
16. Javitt DC and SR Zukin (1991) Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 148, 1301-1308. Review.
17. Jodo E, Y Suzuki, T Katayama, KY Hoshino, S Takeuchi, S Niwa and Y Kayama (2005) Activation of medial prefrontal cortex by phencyclidine is mediated via a hippocampo-prefrontalpathway. Cereb. Cortex 15, 663-669.
18. Kargieman L, N Santana, G Mengod, P Celada and F Artigas (2007) Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine. Proc. Natl Acad. Sci. USA 104, 14843-14848.
19. Keshavan MS, CF Reynolds 3rd, MJ Miewald, DM Montrose, JA Sweeney, RC Vasko Jr and DJ Kupfer (1998) Delta sleep deficits in schizophrenia: evidence from automated analyses of sleep data. Arch. Gen. Psychiatry 55, 443-448.
20. Krystal JH, LP Karper, JP Seibyl, GK Freeman, R Delaney, JD Bremner, GR Heninger, MB Bowers and DS Charney (1994) Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch. Gen. Psychiatry 51, 199-214.
21. Krystal JH, DC D'Souza, D Mathalon, E Perry, A Belger and R Hoffman (2003) NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: Toward a paradigm shift in medication development. Psychopharmacology (Berl.) 169, 215-233. Review.
22. Kuroda M, J Yokofujita and K Murakami (1998) An ultrastructural study of the neural circuit between the prefrontal cortex and the mediodorsal nucleus of the thalamus. Prog. Neurobiol. 54, 417-458.
23. 4 receptor-dependent basolateral amygdala input J. Neurosci. 25, 6066-6075.
24. Lewis DA and JA Lieberman (2000) Catching up on schizo phrenia: Natural history and neurobiology. Neuron 28, 325-334.
25. Lewis DA, T Hashimoto and DW Volk (2005) Cortical inhibitory neurons and schizophrenia. Nat. Rev. Neurosci. 6, 312-324.
26. López-Gil J, Z Babot, M Amargós-Bosch, C Suñol, F Artigas and A Adell (2007) Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat. Neuropsychopharmacology 32, 2087-2097.
27. Lorrain DS, CS Baccei, LJ Bristow, JJ Anderson and MA Varney (2003) Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: Modulation by a group II selective metabotropic glutamate receptor agonist LY379268. Neuroscience 117, 697-706.
28. Malhotra AK, DA Pinals, H Weingartner, K Sirocco, CD Missar, D Pickar and A Breier (1994) NMD A receptor function and human cognition: The effects of ketamine in healthy volunteers. Neuropsychopharmacology 14, 301-307.
29. Marshall L, H Helgadottir, M Molle and J Born (2006) Boosting slow oscillations during sleep potentiates memory. Nature 444, 610-613.
30. Martin P, N Waters, S Waters, A Carlsson and M Carlsson (1997) MK-801-induced hyperlocomotion: Differential effects of M100907, SDZ PSD 958 and raclopride. Eur.J. Pharmacol. 335, 107-116.
31. Martin P, ML Carlsson and S Hjorth (1998) Systemic PCP treatment elevates brain extracellular 5-HT: A microdialysis study in awake rats. Neuroreport 9, 2985-2988.
32. Mathé JM, GG Nomikos, KH Blakeman and TH Svensson (1999) Differential actions of dizocilpine (MK-801) on the mesolimbic and mesocortical dopamine systems: Role of neuronal activity. Neuropharmacology 38, 121-128.
33. McKenna JT and RP Vertes (2004) Afferent projections to nucleus reuniens of the thalamus. J. Comp. Neurol. 480, 115-142.
34. Millan MJ, M Brocco, A Gobert, F Joly, K Bervoets, JM Rivet, A Newman-Tancredi, V Audinot and S Maurel (1999) Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: Importance of nucleus accumbens 5-HT 2A sites for PCP-induced locomotion in the rat. Eur. J. Neurosci. 11, 4419-4432.
35. Miller EK and JD Cohen (2001) An integrative theory of prefrontal cortex function. Annu. Rev. Neurosci. 24, 167-202.
36. Mirjana C, M Baviera, RW Invernizzi and C Balducci (2004) The serotonin 5-HT 2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex. Neuropsychopharmacology 29, 1637-1647.
37. Moghaddam B, B Adams, A Verma and D Daly (1997) Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 17, 2921-2927.
38. Nelson CL, JA Burk, JP Bruno and M Sarter (2002) Effects of acute and repeated systemic administration of ketamine on prefrontal acetylcholine release and sustained attention performance in rats. Psychopharmacology (Berl.) 161, 168-179.
39. Newcomer JW, NB Farber, V Jevtovic-Todorovic, G Selke, AK Melson, T Hershey, S Craft and JW Olney (1999) Ketamine-induced NMDA receptor hypofunction as model of memory impairment and psychosis. Neuropsychopharmacology 20, 106-118.
40. Nowak LG, R Azouz, MV Sanchez-Vives, CM Gray and DA McCormick (2003) Electrophysiological classes of cat primary visual cortical neurons in vivo as revealed by quantitative analyses. J. Neurophysiol. 89, 1541-1566.
41. Paxinos G and C Watson (1998) The Rat Brain in Stereotaxic Coordinates, 4th Edition (Academic Press:SYdney).
42. Puig MV, P Celada, L Díaz-Mataix and F Artigas (2003) In vivo modulation of the activity of pyramidal neurons in the rat medial prefrontal cortex by 5-HT 2A receptors. Relationship to thalamocortical afferents. Cereb. Cortex 13, 1870-1882.
43. Sekimoto M, M Kato, T Watanabe, N Kajimura and K Takahashi (2007) Reduced frontal asymmetry of delta waves during all-night sleep in schizophrenia. Schizophr. Bull. 33, 1307-1311.
44. Serrats J, F Artigas, G Mengod and R Cortés (2003) GABA B receptor mRNA in the raphe nuclei: Co-expression with serotonin transporter and glutamic acid decarboxylase. J. Neurochem. 84, 743-752.
45. Schmidt CJ and GM Fadayel (1996) Regional effects of MK-801 on dopamine release: Effects of competitive NMDA or 5-HT 2A receptor blockade. J. Pharmacol. Exp. Ther. 277, 1541-1549.
46. Steriade M, A Nuñez and F Amzica (1993) A novel slow (1 Hz) oscillation of neocortical neurons in vivo: Depolarizing and hyperpolarizing components. J. Neurosci. 13, 3252-3265.
47. Steriade M (2004) Neocortical cell classes are flexible entities. Nat. Rev. Neurosci. 2, 121-134.
48. Steriade M (2006) Grouping of brain rhythms in corticothalamic systems. Neuroscience 137, 1087-1106.
49. Stickgold R (2005) Sleep-dependent memory consolidation. Nature 437, 1272-1278.
50. Stickgold R, JA Hobson, R Fosse and M Fosse (2001) Sleep, learning, and dreams: Off-line memory reprocessing. Science 294, 1052-1057.
51. Suzuki Y, E Jodo, S Takeuchi, S Niwa and Y Kayama (2002) Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons in freely moving rats. Neuroscience 114, 769-779.
52. Tseng KY, N Mallet, KL Toreson, C Le Moine, F Gonon and P O'Donnell (2006) Excitatory response of prefrontal cortical fast-spiking interneurons to ventral tegmental area stimulation in vivo. Synapse 59, 412-417.
53. Vertes RP (2004) Differential projections of the infralimbic and prelimbic cortex in the rat. Synapse 51, 32-58.
54. Vertes RP (2006) Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat. Neuroscience 29, 1-20.