Intensity dependence of auditory P2 in monozygotic twins discordant for Vietnam combat: Associations with posttraumatic stress disorder

Journal of Rehabilitation Research and Development

Volumn 45, Issue 3, 2008, Pages 437-450

  Metzger, Linda J ^a,b,c   Pitman, Roger K ^a,b,c   Miller, Gregory A ^d   Paige, Stephen R ^e   Orr, Scott P ^a,b,c,f  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^f Manchester VA Medical Center   (United States)

Author keywords

5 HT; Auditory intensity dependence; Combat disorder; Event related potentials; Posttraumatic; PTSD; Rehabilitation; Serotonin; Stress disorders; Twin studies

Indexed keywords

5-HT; AUDITORY INTENSITY DEPENDENCE; COMBAT DISORDER; EVENT-RELATED POTENTIALS; POSTTRAUMATIC; PTSD; REHABILITATION; SEROTONIN; STRESS DISORDERS; TWIN STUDIES;

PATIENT REHABILITATION;

ADULT; ARTICLE; AUDITORY STIMULATION; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE PREDISPOSITION; EVOKED AUDITORY RESPONSE; HUMAN; MALE; MONOZYGOTIC TWINS; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; TWIN DISCORDANCE; VETERAN; VIET NAM; WAR; ANALYSIS OF VARIANCE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOMETRY; TWINS;

ANALYSIS OF VARIANCE; EVOKED POTENTIALS, AUDITORY; HUMANS; MALE; MIDDLE AGED; PSYCHOMETRICS; STRESS DISORDERS, POST-TRAUMATIC; TWINS, MONOZYGOTIC; VETERANS; VIETNAM CONFLICT;

EID: 63249098238     PISSN: 07487711     EISSN: 07487711     Source Type: Journal    
DOI: 10.1682/JRRD.2007.07.0100     Document Type: Article

References (48)

1. Paige SR, Reid GM, Allen MG, Newton JE. Psychophysiological correlates of posttraumatic stress disorder in Vietnam veterans. Biol Psychiatry. 1990;27(4):419-430
2. Buchsbaum MS, Stevens SS. Neural events and psychophysical law. Science. 1971;172(982):502.
3. Buchsbaum MS, Silverman J. Stimulus intensity control and the cortical evoked response. Psychosom Med. 1968; 30(1):12-22.
4. Friedman J, Meares R. Cortical evoked potentials and extraversion. Psychosom Med. 1979;41(4):279-286
5. Juckel G, Molnár M, Hegerl U, Csépe V, Karmos G. Auditory- evoked potentials as indicator of brain serotonergic activity - First evidence in behaving cats. Biol Psychiatry. 1997;41(12):1181-1195
6. Brocke B, Beauducel A, John R, Debener S, Heilemann H. Sensation seeking and affective disorders: Characteristics in the intensity dependence of acoustic evoked potentials. Neuropsychobiology. 2000;41(1):24-30.
7. Zuckerman M. The psychophysiology of sensation seeking. J Pers. 1990;58(1):313-345
8. Hegerl U, Karnauchow I, Herrmann WM, Müller-Oerlinghausen B. Intensity dependence of auditory evoked N1/P2 component and personality. Neuropsychobiology. 1992;26(3):166-172
9. Lewine JD, Thoma RJ, Provencal SL, Edgar C, Miller GA, Canive JM. Abnormal stimulus-response intensity functions in posttraumatic stress disorder: An electrophysiological investigation. Am J Psychiatry. 2002;159(10):1689-1695
10. McPherson WB, Newton JE, Ackerman P, Oglesby DM, Dykman RA. An event-related brain potential investigation of PTSD and PTSD symptoms in abused children. Integr Physiol Behav Sci. 1997;32(1):31-42.
11. Metzger LJ, Carson MA, Paulus LA, Lasko NB, Paige SR, Pitman RK, Orr SP. Event-related potentials to auditory stimuli in female Vietnam nurse veterans with posttraumatic stress disorder. Psychophysiology. 2002;39(1):49-63.
12. Hegerl U, Juckel G. Intensity dependence of auditory evoked potentials as an indicator of central serotonergic neurotransmission: A new hypothesis. Biol Psychiatry. 1993;33(3):173-187 [PMID: 8383545] (Pubitemid 23089966)
13. Davis LL, Suris A, Lambert MT, Heimberg C, Petty F. Post-traumatic stress disorder and serotonin: New directions for research and treatment. J Psychiatry Neurosci. 1997;22(5):318-326
14. Juckel G, Hegerl U, Molnár M, Csépe V, Karmos G. Auditory evoked potentials reflect serotonergic neuronal activity - A study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus. Neuropsychopharmacology. 1999;21(6):710-716
15. Wang W, Wang Y, Fu X, Liu J, He C, Dong Y, Livesley WJ, Jang KL. Cerebral information processing in personality disorders: I. Intensity dependence of auditory evoked potentials. Psychiatry Res. 2006;141(2):173-183
16. Carrillo-de-la-Peña MT, Vallet M, Pérez MI, Gómez- Perretta C. Intensity dependence of auditory-evoked cortical potentials in fibromyalgia patients: A test of the generalized hypervigilance hypothesis. J Pain. 2006;7(7):480-487
17. Siniatchkin M, Kropp P, Neumann M, Gerber W, Stephani U. Intensity dependence of auditory evoked cortical potentials in migraine families. Pain. 2000;85(1-2):247-254
18. Wang W, Timsit-Berthier M, Schoenen J. Intensity dependence of auditory evoked potentials is pronounced in migraine: An indication of cortical potentiation and low serotonergic neurotransmission? Neurology. 1996;46(5):1404-1409
19. Senkowski D, Linden M, Zubrägel, Bär T, Gallinat J. Evidence for disturbed cortical signal processing and altered serotonergic neurotransmission in generalized anxiety disorder. Biol Psychiatry. 2003;53(4):304-314
20. Eison MS. Serotonin: A common neurobiologic substrate in anxiety and depression. J Clin Psychopharmacol. 1990; 10(3 Suppl):26S-30S.
21. Linka T, Sartory G, Bender S, Gastpar M, Müller BW. The intensity dependence of auditory ERP components in unmedicated patients with major depression and healthy controls. An analysis of group differences. J Affect Disord. 2007;103(1-3):139-145
22. Paige SR, Fitzpatrick DF, Kline JP, Balogh SE, Hendricks SE. Event-related potential amplitude/intensity slopes predict response to antidepressants. Neuropsychobiology. 1994;30(4):197-201.
23. Lee TW, Yu YW, Chen TJ, Tsai SJ. Loudness dependence of the auditory evoked potential and response to antidepressants in Chinese patients with major depression. J Psychiatry Neurosci. 2005;30(3):202-205
24. Gallinat J, Bottlender R, Juckel G, Munke-Puchner A, Stotz G, Kuss HJ, Mavrogiorgou P, Hegerl U. The loudness dependency of the auditory evoked N1/P2-component as a predictor of the acute SSRI response in depression. Psychopharmacology (Berl). 2000;148(4):404-411
25. Kähkönen S, Jääskeläinen IP, Pennanen S, Liesivuori J, Ahveninen J. Acute trytophan depletion decreases intensity dependence of auditory evoked magnetic N1/P2 dipole source activity. Psychopharmacology (Berl). 2002;164(2):221-227
26. Debener S, Strobel A, Kürschner K, Kranczioch C, Hebenstreit J, Maercher A, Beauducel A, Brocke B. Is auditory evoked potential augmenting/reducing affected by acute tryptophan depletion? Biol Psychology. 2002;59(2):121-133 [PMID: 11911935] (Pubitemid 34242636)
27. Tuchtenhagen F, Daumann J, Norra C, Gobbelé R, Becker S, Pelz S, Sass H, Buchner H, Gouzoulis-Mayfrank E. High intensity dependence of auditory evoked dipole source activity indicates decreased serotonergic activity in abstinent ecstasy (MDMA) users. Neuropsychopharmacology. 2000;22(6):608-617
28. Croft RJ, Klugman A, Baldeweg T, Gruzelier JH. Electrophysiological evidence of serotonergic impairment in long-term MDMA ("ecstasy") users. Am J Psychiatry. 2001;158(10):1687-1692
29. Daumann J, Till B, Fischermann T, Rezk M, Gouzoulis-Mayfrank E. Intensity dependence of auditory evoked dipole source activity in polydrug ecstasy users: Evidence from an 18 months longitudinal study. J Psychopharmacol. 2006;20(2):236-244
30. Hensch T, Wargelius HL, Herold U, Lesch KP, Oreland L, Brocke B. Further evidence for an association of 5-HTTLPR with intensity dependence of auditory-evoked potentials. Neuropsychopharmacology. 2006;31(9):2047-2054
31. Strobel A, Debener S, Schmidt D, Hünnerkopf R, Lesch KP, Brocke B. Allelic variation in serotonin transporter function associated with the intensity dependence of the auditory evoked potential. Am J Med Genet B Neuropsychiatr Genet. 2003;118(1):41-47.
32. Gallinat J, Senkowski D, Wenicke C, Juckel G, Becker I, Sander T, Smolka M, Hegerl U, Rommelspacher H, Winterer G, Herrmann WM. Allelic variants of the functional promoter polymorphism of the human serotonin transporter gene is associated with auditory cortical stimulus processing. Neuropsychopharmacology. 2003;28(3):530-532
33. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274(5292):1527-1531
34. Lee HJ, Lee MS, Kang RH, Kim H, Kim SD, Kee BS, Kim YH, Kim YK, Kim JB, Yeon BK, Oh KS, Oh BH, Yoon JS, Lee C, Jung HY, Chee IS, Paik IH. Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder. Depress Anxiety. 2005;21(3):135-139
35. Pollock BG, Ferrell RE, Mulsant BH, Mazumdar S, Miller M, Sweet RA, Davis S, Kirshner MA, Houck PR, Stack JA, Reynolds CF, Kupfer DJ. Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression. Neuropsychopharmacology. 2000;23(5):587-590
36. Orr SP, Metzger LJ, Lasko NB, Macklin ML, Hu FB, Shalev AY, Pitman RK; Harvard/Veterans Affairs Post-traumatic Stress Disorder Twin Study Investigators. Physiologic responses to sudden, loud tones in monozygotic twins discordant for combat exposure: Association with posttraumatic stress disorder. Arch Gen Psychiatry. 2003:60(3):283-288
37. Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM. The development of a Clinician-Administered PTSD Scale. J Trauma Stress. 1995;8(1):75-90.
38. Janes GR, Goldberg J, Eisen SA, True WR. Reliability and validity of a combat exposure index for Vietnam era veterans. J Clin Psychol. 1991;47(1):80-86.
39. Derogatis LR. SCL-90-R: Administration, scoring & procedures manual-II for the revised version and other instruments of the psychopathology rating scale series. Towson (MD): Clinical Psychometric Research; 1983.
40. Jasper HH. The ten-twenty electrode system of the International Federation. J Electroencephalogr Clin Neurophysiol. 1958;10:371-375
41. Little RC, Miliken GA, Stroup WW, Wolfinger RD. SAS system for mixed models. Cary (NC): SAS Institute; 1996.
42. Miller GA, Chapman JP. Misunderstanding analysis of covariance. J Abnorm Psychol. 2001;110(1):40-48.
43. Buydens-Branchey L, Noumair D, Branchey M. Duration and intensity of combat exposure and posttraumatic stress disorder in Vietnam veterans. J Nerv Ment Dis. 1990;178(9):582-587
44. Lund M, Foy D, Sipprelle C, Strachan A. The Combat Exposure Scale: A systematic assessment of trauma in the Vietnam War. J Clin Psychol. 1984;40(6):1323-1338
45. Koenen KC, Stellman SD, Dohrenwend BP, Sommer JF JR, Stellman JM. The consistency of combat exposure reporting and course of PTSD in Vietnam War veterans. J Trauma Stress. 2007;20(1):3-13.
46. Brocke B, Beauducel A, Tasche KG. Biophysiological bases and behavioral correlates of sensation seeking: Contributions to a multilevel validation. Pers Individ Dif. 1999;26(6):1103-1123
47. Graeff FG. Neurotransmitters in the dorsal periaqueductal grey and animal models of panic anxiety. In: Briley M, File SE, editors. New concepts in anxiety. Boca Raton (FL): CRC Press; 1991.
48. Goddard AW, Woods SW, Charney DS. A critical review of the role of norepinephrine in panic disorder: Focus on its interaction with serotonin. In: Westenberg HG, Boer JA, Murphy DL, editors. Advances in the neurobiology of anxiety disorders. New York (NY): Wiley; 1996. p. 107-137