Macromolecular conformation of chitosan in dilute solution: A new global hydrodynamic approach

Carbohydrate Polymers

Volumn 76, Issue 4, 2009, Pages 616-621

  Morris, Gordon A ^a   Castile, Jonathan ^a   Smith, Alan ^a   Adams, Gary G ^a   Harding, Stephen E ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Chitosan; Equivalent radii; Intrinsic viscosity; Molar mass; Molar weight; Sedimentation coefficient; Semi flexible rod conformation

Indexed keywords

BIOLOGICAL MEMBRANES; CHITIN; CHROMATOGRAPHIC ANALYSIS; FLUID DYNAMICS; HYDROGELS; LAND USE; LIGHT SCATTERING; MACROMOLECULES; MOLAR MASS; MULTILAYERS; POLYETHYLENE TEREPHTHALATES; SIZE EXCLUSION CHROMATOGRAPHY; VISCOSITY;

EQUIVALENT RADII; INTRINSIC VISCOSITY; MOLAR WEIGHT; SEDIMENTATION COEFFICIENT; SEMI-FLEXIBLE ROD CONFORMATION;

CHITOSAN;

EID: 63149194922     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2008.11.025     Document Type: Article

References (37)

1. Berth G., Dautzenberg H., and Peter M.G. Physico-chemical characterization of chitosans varying in degree of acetylation. Carbohydrate Polymers 36 (1998) 205-216
2. Bohdanecky M. New method for estimating the parameters of the wormlike chain model from the intrinsic viscosity of stiff-chain polymers. Macromolecules 16 (1983) 1483-1493
3. Brugnerotto J., Desbrières J., Roberts G., and Rinaudo M. Characterization of chitosan by steric exclusion chromatography. Polymer 42 (2001) 9921-9927
4. Bushin S.V., Tsvetkov V.N., Lysenko Y.B., and Emel'yanov V.N. Conformational properties and rigidity of molecules of ladder polyphenylsiloxane in solutions according the data of sedimentation-diffusion analysis and viscometry. Vysokomolekulyarnye Soedineniya A23 (1981) 2494-2503
5. Cölfen H., Berth G., and Dautzenberg H. Hydrodynamic studies on chitosans in aqueous solution. Carbohydrate Polymers 45 (2001) 373-383
6. Errington N., Harding S.E., Vårum K.M., and Illum L. Hydrodynamic characterisation of chitosans varying in degree of acetylation. International Journal of Biological Macromolecules 15 (1993) 113-117
7. Fee M., Errington N., Jumel K., Illum L., Smith A., and Harding S.E. Correlation of SEC/MALLS with ultracentrifuge and viscometric data for chitosans. European Biophysical Journal 32 (2003) 457-464
8. Gralén N. Sedimentation and diffusion measurements on cellulose and cellulose derivatives (1944), PhD Dissertation, University of Uppsala, Sweden
9. Harding S.E. The Intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation and application to structure in dilute solution. Progress in Biophysics and Molecular Biology 68 (1997) 207-262
10. Harding S.E. Analysis of polysaccharides size, shape and interactions. In: Scott D.J., Harding S.E., and Rowe A.J. (Eds). Analytical ultracentrifugation techniques and methods (2005), Royal Society of Chemistry, Cambridge 231-252
11. Harding S.E., Berth G., Ball A., Mitchell J.R., and Garcìa de la Torre J. The molar mass distribution and conformation of citrus pectins in solution studied by hydrodynamics. Carbohydrate Polymers 168 (1991) 1-15
12. Harding S.E., Davis S.S., Deacon M.P., and Fiebrig I. Biopolymer mucoadhensives. In: Harding S.E. (Ed). Biotechnology and genetic engineering reviews Vol. 16 (1999), Intercept: Andover, UK 41-86
13. Harding S.E., Vårum K.M., Stokke B.T., and Smidsrød O. Molar mass determination of polysaccharides. In: White C.A. (Ed). Advances in carbohydrate analysis Vol. 1 (1991), JAI Press Limited: Greenwich, USA 63-144
14. Kasaai M.R. Calculation of Mark-Houwink-Sakurada (MHS) equation viscometric constants for chitosan in any solvent-temperature system using experimental reported viscometric constants data. Carbohydrate Polymers 68 (2006) 477-488
15. Kratky O., and Porod G. Röntgenungtersuchung gelöster fadenmoleküle. Recueil Des Travaux Chimiques Des Pays-Bas 68 (1949) 1106-1109
16. Lamarque G., Lucas J.-M., Viton C., and Domard A. Physicochemical behavior of homogeneous series of acetylated chitosans in aqueous solution: Role of various structural parameters. Biomacromolecules 6 (2005) 131-142
17. Mazeau K., and Rinaudo M. The prediction of the characteristics of some polysaccharides from molecular modelling. Comparison with effective behaviour. Food Hydrocolloids 18 (2004) 885-898
18. Morris G.A., Foster T.J., and Harding S.E. The effect of degree of esterification on the hydrodynamic properties of citrus pectin. Food Hydrocolloids 14 (2000) 227-235
19. Morris G.A., García de al Torre J., Ortega A., Castile J., Smith A., and Harding S.E. Molecular flexibility of citrus pectins by combined sedimentation and viscosity analysis. Food Hydrocolloids 22 (2008) 1435-1442
20. Ortega A., and García de la Torre J. Equivalent radii and ratios of radii from solution properties as indicators of macromolecular conformation, shape, and flexibility. Biomacromolecules 8 (2007) 2464-2475
21. Pavlov G.M., Harding S.E., and Rowe A.J. Normalized scaling relations as a natural classification of linear macromolecules according to size. Progress in Colloid and Polymer Science 113 (1999) 76-80
22. Pavlov G.M., Rowe A.J., and Harding S.E. Conformation zoning of large molecules using the analytical ultracentrifuge. Trends in Analytical Chemistry 16 (1997) 401-405
23. Ralston G. Introduction to analytical ultracentrifugation (1993), Beckman Instruments Inc, Palo Alto [pp. 27-28]
24. Rinaudo M. Chitin and chitosan: Properties and applications. Progress in Polymer Science 31 (2006) 603-632
25. Rinaudo M., Milas M., and Le Dung P. Characterization of chitosan. Influence of ionic strength and degree of acetylation on chain expansion. International Journal of Biological Macromolecules 15 (1993) 281-285
26. Rowe A.J. The concentration dependence of transport processes: a general description applicable to the sedimentation, translational diffusion and viscosity coefficients of macromolecular solutes. Biopolymers 16 (1977) 2595-2611
27. Schatz S., Viton C., Delair T., Pichot C., and Domard A. Typical physicochemical behaviors of chitosan in aqueous solution. Biomacromolecules 4 (2003) 641-648
28. Schuck P. Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation. Biophysical Journal 75 (1998) 1503-1512
29. Schuck P. Diffusion-deconvoluted sedimentation coefficient distributions for the analysis of interacting and non-interacting protein mixtures. In: Scott D.J., Harding S.E., and Rowe A.J. (Eds). Analytical ultracentrifugation techniques and methods (2005), Royal Society of Chemistry, Cambridge 26-50
30. Solomon O.F., and Ciutâ I.Z. Détermination de la viscosité intrinsèque de solutions de polymères par une simple détermination de la viscosité. Journal of Applied Polymer Science 24 (1962) 683-686
31. Tanford C. Physical chemistry of macromolecules (1961), John Wiley and Sons, New York
32. Terbojevich M., Cosani A., Conio G., Marsano E., and Bianchi E. Chitosan: Chain rigidity and mesophase formation. Carbohydrate Research 209 (1991) 251-260
33. Tombs M.P., and Harding S.E. Polysaccharide biotechnology (1998), Taylor Francis, London, UK pp. 144-151
34. Velásquez, C. L., Albornoz, J. S., & Barrios, E. M. (2008). Viscosimetric studies of chitosan nitrate and chitosan chlorhydrate in acid free NaCl aqueous solution. E-Polymers, 014. Available from .
35. Vold, I. M. N. (2004). Periodate oxidised chitosans: Structure and solution properties. PhD Dissertation, Norwegian University of Science and Technology, Trondheim, Norway.
36. Wales M., and van Holde K.E. The concentration dependence of the sedimentation constants of flexible macromolecules. Journal of Polymer Science 14 (1954) 81-86
37. Yamakawa H., and Fujii M. Translational friction coefficient of wormlike chains. Macromolecules 6 (1973) 407-415