Discovery of potent and selective DP1 receptor antagonists in the azaindole series

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 8, 2009, Pages 2125-2128

  Leblanc, Yves ^a   Roy, Patrick ^a   Dufresne, Claude ^a   Lachance, Nicolas ^a   Wang, Zhaoyin ^a   O'Neill, Gary ^a   Greig, Gillian ^a   Denis, Danielle ^a   Mathieu, Marie Claude ^a   Slipetz, Deborah ^a   Sawyer, Nicole ^a   Tsou, Nancy ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Azaindoles; DP1 receptor antagonists

Indexed keywords

G PROTEIN COUPLED RECEPTOR; INDOLE DERIVATIVE; LAROPIPRANT; PROSTAGLANDIN RECEPTOR BLOCKING AGENT;

ARTICLE; CHEMICAL REACTION; DOG; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MONKEY; NONHUMAN; SQUIRREL MONKEY;

HUMANS; INDOLES; PROSTAGLANDIN ANTAGONISTS; RECEPTORS, PROSTAGLANDIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 63149161866     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.010     Document Type: Article

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