Inhibition of erythrocyte phosphoribosyltransferases (APRT and HPRT) by Pb2+: A potential mechanism of lead toxicity

Toxicology

Volumn 259, Issue 1-2, 2009, Pages 77-83

  Baranowska Bosiacka, I ^a   Dziedziejko, V ^a   Safranow, K ^a   Gutowska, I ^a   Marchlewicz, M ^a   Dolegowska B ^a   Rac M E ^a   Wiszniewska, B ^a   Chlubek, D ^a  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

Author keywords

APRT; Erythrocyte; Hemolysis; HPRT; Lead (Pb2+); Phosphoribosyltransferases

Indexed keywords

ACETIC ACID; ADENINE PHOSPHORIBOSYLTRANSFERASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LEAD;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ERYTHROCYTE; FEMALE; HEMOLYSATE; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEAD POISONING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENINE PHOSPHORIBOSYLTRANSFERASE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FEMALE; HEMOLYSIS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR; TIME FACTORS;

RATTUS;

EID: 63149128565     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.02.005     Document Type: Article

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