Structural basis for clinical longevity of carbapenem antibiotics in the face of challenge by the common class a β-lactamases from the antibiotic- resistant bacteria

Journal of the American Chemical Society

Volumn 120, Issue 38, 1998, Pages 9748-9752

  Maveyraud, Laurent ^a   Mourey, Lionel ^a   Kotra, Lakshnii P ^a   Pedelacq, Jean Denis ^a   Guillet, Valérie ^a   Mobashery, Shahriar ^a   Samama, Jean Pierre ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; CARBAPENEM;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG INACTIVATION; DRUG STRUCTURE; ENZYME ACTIVITY; STRUCTURE ACTIVITY RELATION;

EID: 0032581949     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9818001     Document Type: Article

References (4)

1. Swartz, M. N. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 2420.
2. Jones, R. N. Am. J. Med. 1996, 700 (suppl. 6A), 3S.
3. Davies, J. E. Antibiotic resistance: origins, evolution, selection and spread; Ciba Foundation Symposium 207; Chadwick, D. J., Goode, J., Eds.; John-Wiley: Chichester, 1997; pp 15-35.
4. Neu. H. C. Science 1992, 257, 1064.