Association of early growth response-1 gene polymorphisms with total IgE and atopy in asthmatic children

Pediatric Allergy and Immunology

Volumn 20, Issue 2, 2009, Pages 142-150

  Chan, Iris H S ^a   Tang, Nelson L S ^a   Leung, Ting F ^a   Huang, W ^a   Lam, Yvonne Y O ^a   Wong, Gary W K ^a   Chan, Juliana C N ^a   Chan, Michael H M ^a   Wong, Chun K ^a   Zhang, Ya P ^a,b   Lam, Christopher W K ^a,c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

Aeroallergen; Asthma; Early growth response 1; Genetic polymorphism; Immunoglobulin E

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; IMMUNOGLOBULIN E;

ADOLESCENT; ADULT; ALLELE; ARTICLE; ASTHMA; ATOPY; AUTOIMMUNITY; CHILD; CHINESE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FORCED EXPIRATORY VOLUME; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; IMMUNOASSAY; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PHARMACOGENETICS; PRESCHOOL CHILD; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SPIROMETRY;

ADOLESCENT; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; CATS; CHILD; CHILD, PRESCHOOL; COCKROACHES; DERMATOPHAGOIDES PTERONYSSINUS; DOGS; EARLY GROWTH RESPONSE PROTEIN 1; EPITOPES; FEMALE; GENOTYPE; HUMANS; IMMUNOGLOBULIN E; LINKAGE DISEQUILIBRIUM; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; SPIROMETRY;

EID: 63149091745     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2008.00757.x     Document Type: Article

References (34)

1. Gashler A, Sukhatme VP. Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog Nucleic Acid Res Mol Biol 1995 : 50 : 191 224.
2. Milbrandt J. A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science 1987 : 238 : 797 9.
3. Sukhatme VP, Kartha S, Toback FG, Taub R, Hoover RG, Tsai-Morris CH. A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens. Oncogene Res 1987 : 1 : 343 55.
4. Bahouth SW, Beauchamp MJ, Vu KN. Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene. Mol Pharmacol 2002 : 61 : 379 90.
5. Hjoberg J, Le L, Imrich A, et al. Induction of early growth-response factor 1 by platelet-derived growth factor in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2004 : 286 : L817 25.
6. Martinez JM, Baek SJ, Mays DM, Tithof PK, Eling TE, Walker NJ. EGR1 is a novel target for AhR agonists in human lung epithelial cells. Toxicol Sci 2004 : 82 : 429 35.
7. Eto K, Kaur V, Thomas MK. Regulation of insulin gene transcription by the immediate-early growth response gene Egr-1. Endocrinology 2006 : 147 : 2923 35.
8. Silverman ES, Du J, De Sanctis GT, et al. Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. Am J Respir Cell Mol Biol 1998 : 19 : 316 23.
9. Thiel G, Schoch S, Petersohn D. Regulation of synapsin I gene expression by the zinc finger transcription factor zif268/egr-1. J Biol Chem 1994 : 269 : 15294 301.
10. Li B, Power MR, Lin TJ. De novo synthesis of early growth response factor-1 is required for the full responsiveness of mast cells to produce TNF and IL-13 by IgE and antigen stimulation. Blood 2006 : 107 : 2814 20.
11. Cho SJ, Kang MJ, Homer RJ, et al. Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling. J Biol Chem 2006 : 281 : 8161 8.
12. Okada M, Fujita T, Sakaguchi T, et al. Extinguishing Egr-1-dependent inflammatory and thrombotic cascades after lung transplantation. FASEB J 2001 : 15 : 2757 9.
13. Ressler B, Lee RT, Randell SH, Drazen JM, Kamm RD. Molecular responses of rat tracheal epithelial cells to transmembrane pressure. Am J Physiol Lung Cell Mol Physiol 2000 : 278 : L1264 72.
14. Zhang W, Yan SD, Zhu A, et al. Expression of Egr-1 in late-stage emphysema. Am J Pathol 2000 : 157 : 1311 20.
15. Liu C, Rangnekar VM, Adamson E, Mercola D. Suppression of growth and transformation of apoptosis by Egr-1. Cancer Gene Ther 1998 : 5 : 3 28.
16. Silverman ES, Collins T. Pathways of Egr-1-mediated gene transcription in vascular biology. Am J Pathol 1999 : 154 : 665 70.
17. Silverman ES, De Sanctis GT, Boyce J, et al. The transcription factor EGR-1 modulates TNF-α, IgE, and airway responsiveness in mice. Am J Respir Crit Care Med 2001 : 163 : 778 85.
18. Postma DS, Bleecker ER, Amelung PJ, et al. Genetic susceptibility to asthmabronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995 : 333 : 894 900.
19. American Thoracic Society. Medical section of the American Lung Association. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987 : 136 : 225 44.
20. Leung TF, Tang NL, Sung YM, et al. The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children. Pediatr Allergy Immunol 2003 : 14 : 255 60.
21. Ip MS, Karlberg EM, Karlberg JP, Luk KD, Leong JC. Lung function reference values in Chinese children and adolescents in Hong Kong. I. Spirometric values and comparison with other populations. Am J Respir Crit Care Med 2000 : 162 : 424 9.
22. Brand E, Herrmann SM, Nicaud V, et al. Identification of two polymorphisms in the early growth response protein-1 gene: possible association with lipid variables. J Mol Med 2000 : 78 : 81 6.
23. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005 : 21 : 263 5.
24. Marsh DG, Neely JD, Breazeale DR, et al. Total serum IgE levels and chromosome 5q. Clin Exp Allergy 1995 : 25 (Suppl. 2 79 83.
25. Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunol Rev 2004 : 202 : 175 90.
26. Lukacs NW, Tekkanat KK, Berlin A, et al. Respiratory syncytial virus predisposes mice to augmented allergic airway responses via IL-13-mediated mechanisms. J Immunol 2001: 167: 1060-5. Erratum in: J Immunol 2005 : 175 : 8442.
27. Hancock A, Armstrong L, Gama R, Millar A. Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. Am J Respir Cell Mol Biol 1998 : 18 : 60 5.
28. Leung TF, Wong CK, Chan IH, Ip WK, Lam CW, Wong GW. Plasma concentration of thymus and activation-regulated chemokine is elevated in childhood asthma. J Allergy Clin Immunol 2002 : 110 : 404 9.
29. Chan IH, Leung TF, Tang NL, et al. Gene-gene interactions for asthma and plasma total IgE concentration in Chinese children. J Allergy Clin Immunol 2006 : 117 : 127 33.
30. Leung TF, Tang NL, Li CY, Lam CW, Wong GW, Fok TF. Association between TARC C-431T and atopy and asthma in children. J Allergy Clin Immunol 2004 : 114 : 199 202.
31. Moffatt MF, Schou C, Faux JA, et al. Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample. Eur J Hum Genet 2001 : 9 : 341 46.
32. Xu J, Postma DS, Howard TD, et al. Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet 2000 : 67 : 1163 73.
33. A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA). Nat Genet 1997 : 15 : 389 92.
34. Leung R, Ho P, Lam CW, Lai CK. Sensitisation to inhaled allergens as a risk factor for asthma and allergic disease in Chinese population. J Allergy Clin Immunol 1997 : 99 : 594 9.