The nutrient formula containing eicosapentaenoic acid and docosahexaenoic acid benefits the fatty acid status of patients receiving long-term enteral nutrition

Tohoku Journal of Experimental Medicine

Volumn 217, Issue 1, 2009, Pages 23-28

  Munakata, Mitsutoshi ^a,b   Nishikawa, Masazumi ^c   Togashi, Noriko ^d   Nio, Eiko ^d   Kobayashi, Yasuko ^e   Omura, Kiyoshi ^e   Haginoya, Kazuhiro ^a   Tanaka, Soichiro ^a   Abe, Takuya ^c,f   Hishinuma, Takanori ^f   Chida, Nobukazu ^d   Tsuchiya, Shigeru ^b   Onuma, Akira ^a  

^a Takuto Rehabilitation Center for Children   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c MIYAGI UNIVERSITY   (Japan)

^d EKO RYOUIKUEN Hospital Home for Children   (Japan)

^e National Hospital Organization Sendai Nishitaga Hospital   (Japan)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

Arachidonic acid; Docosahexaenoic acid; Dysphagia; Eicosapentaenoic acid; Enteral nutrition; Essential fatty acid

Indexed keywords

DOCOSAHEXAENOIC ACID; ESSENTIAL FATTY ACID; FATTY ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENTERIC FEEDING; FATTY ACID BLOOD LEVEL; FEMALE; HUMAN; IN VIVO STUDY; LIPID COMPOSITION; LONG TERM CARE; MALE; NEUROLOGIC DISEASE; NUTRIENT;

ADULT; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; ENTERAL NUTRITION; FATTY ACIDS; FEMALE; FOOD, FORMULATED; HUMANS; MALE; TIME FACTORS;

EID: 63049127058     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.217.23     Document Type: Article

References (22)

1. Aiko, S., Yoshizumi, Y., Tsuwano, S., Shimanouchi, M., Sugiura, Y. & Maehara, T (2005) The effects of immediate enteral feeding with a formula containing high levels of ω-3 fatty acids in patients after surgery for esophageal cancer. J. Parenter. Enteral. Nutr., 29, 141-147.
2. Beblo, S., Reinhardt, H., Demmelmair, H., Muntau, A.C. & Koletzko, B. (2007) Effect of fish oil supplementation on fatty acid status, coordination, and fine motor skills in children with phenylketonuria. J. Pediatr., 150, 479-484.
3. Bjerve, K.S., Mostad, I.L. & Thoresen, L. (1987) Alpha-linolenic acid deficiency in patients on long-term gastric-tube feeding: Estimation of linolenic acid and long-chain unsaturated n-3 fatty acid requirement in man. Am. J. Clin. Nutr., 45, 66-77.
4. Brenna, J.T. (2002) Efficiency of conversion of α-linolenic acid to long chain n-3 fatty acids in man. Curr. Opin. Clim. Nutr. Metab. Care, 5, 127-132.
5. Burdge, G.C., Jones, A.E. & Wootton SA. (2002) Eicosapentaenoic and docosapentaenoic acids are the principal products of α-linolenic acid metabolism in young men. Br. J. Nutr., 88, 355-363.
6. Chida, N., Hirono, H. & Arakawa, T. (1972) Effects of dietary folate deficiency on fatty acid composition of myelin cerebroside in growth rats. Tohoku J. Exp. Med., 108, 219-224.
7. Davis, B.C. & Kris-Etherton, P.M. (2003) Achieving optimal essential fatty acid status in vegetarians: Current knowledge and practical implications. Am. J. Clin. Nutr., 78, 640S-646S.
8. Dickerson, R.N., Brown, R.O., Hanna, D.L. & Williams, J.E. (2003) Energy requirements of non-ambulatory, tube-fed adult patients with cerebral palsy and chronic hypothermia. Nutrition, 19, 741-746.
9. Folch, J., Lees, M. & Sloane-Stanley, G.H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 226, 497-509.
10. Geppert, J., Kraft, V., Demmelmair, H. & Koletzko, B. (2005) Docosahexaenoic acid supplementation in vegetarians effectively increases omega-3 index: A randomized trial. Lipids, 40, 807-814.
11. Gerster, H. (1995) The use of n-3 PUFAs (fish oil) in interal nutrition. Int. J. Vitam. Nutr. Res., 65, 3-20.
12. Goyens, P.L., Spilker, M.E., Zock, P.L., Katan, M.B. & Mensink, R.P. (2006) Conversion of α-linolenic acid in humans is influenced by the absolute amounts of α-linolenic acid and linoleic acid in the diet and not by their ratio. Am. J. Clin. Nutr., 84, 44-53.
13. Holman, R.T., Johnson, S.B. & Hatch, T.F. (1982) A case of human linolenic acid deficiency involving neurological abnormalities. Am. J. Clin. Nutr., 35, 617-623.
14. Innis, S.M. (2007) Dietary (n-3) fatty acids and brain development. J. Nutr., 137, 855-859.
15. Kinsella, J.E., Lokesh, B. & Stone, R.A. (1990) Dietary n-3 poly-unsaturated fatty acids and amelioration of cardiovascular disease: Possible mechanisms. Am. J. Clin. Nutr., 52, 1-28.
16. Kumode, M. (2003) Management of nutrition in children and adults with severe motor and intellectual disabilities. No To Hattatsu (Tokyo), 35, 206-210.
17. Munakata, M., Kobayashi, K., Niisato-Nezu, J., Tanaka, S., Kakisaka, Y., Ebihara, T., Ebihara, S, Haginoya, K., Tsuchiya, S. & Onuma A. (2008) Olfactory stimulation using black pepper oil oral facilitates oral feeding in pediatric patients receiving long-term enteral nutrition. Tohoku J. Exp. Med., 214, 327-332.
18. R Development Core Team. (2005) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
19. Richardson, T.J. & Sgoutas, D. (1975) Essential fatty acid deficiency in four adult patients during total parenteral nutrition. Am. J. Clin. Nutr., 18, 258-263.
20. Sugano, M. (1996) Characteristics of fats in Japanese diets and current recommendations. Lipids, 31, S283-S286.
21. Tanaka, Y., Mizote, H., Inada, H., Motohiro, T., Kobayashi, H., Fukahori, S., So, H., Otani, M., Nakamizo, H., Asagiri, K., Akiyoshi, K., Tsuru, T. & Hikida, S. (2004) Efficacy of n-3 polyunsaturated fatty acid enriched enteral nutrient solution in relieving oxidative stress in patients with severe psychophysiologic disorders. Kurume Med. J., 51, 83-90.
22. Wu, W.H., Lu, S.C., Wang, T.F, Jou, H.J. & Wang, T.A. (2006) Effects of docosahexaenoic acid sdpplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in post-menopausal vegetarian women. Eur. J. Clin. Nutr., 60, 386-392.