Elevated levels of platelet microparticles in carotid atherosclerosis and during the postprandial state

Thrombosis Research

Volumn 123, Issue 6, 2009, Pages 881-886

  Michelsen, Annika E ^a   Notø, Ann Trude ^b   Brodin, Ellen ^b   Mathiesen, Ellisiv B ^c   Brosstad, Frank ^a   Hansen, John Bjarne ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b Center for Atherothrombotic Research in Tromsø CART   (Norway)

^c UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Carotid atherosclerosis; Microparticles; Platelets; Postprandial lipemia

Indexed keywords

ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; OMEGA 3 FATTY ACID; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD LEVEL; CARDIOVASCULAR RISK; CAROTID ARTERY; CAROTID ATHEROSCLEROSIS; CONTROLLED STUDY; DRUG UTILIZATION; FAT TOLERANCE TEST; FEMALE; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; MAJOR CLINICAL STUDY; MALE; PLATELET MICROPARTICLE; POPULATION RESEARCH; POSTPRANDIAL STATE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; ULTRASOUND;

AGED; BLOOD PLATELETS; CAROTID ARTERY DISEASES; CAROTID STENOSIS; CASE-CONTROL STUDIES; DIETARY FATS; FEMALE; HUMANS; HYPERTRIGLYCERIDEMIA; MALE; POSTPRANDIAL PERIOD; TRIGLYCERIDES;

EID: 63049111696     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2008.10.016     Document Type: Article

References (50)

1. Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352 16 (2005) 1685-1695
2. Davi G., and Patrono C. Platelet activation and atherothrombosis. N Engl J Med 357 24 (2007) 2482-2494
3. Gawaz M. Role of platelets in coronary thrombosis and reperfusion of ischemic myocardium. Cardiovasc Res 61 3 (2004) 498-511
4. Kockx M.M. Apoptosis in the atherosclerotic plaque: quantitative and qualitative aspects. Arterioscler Thromb Vasc Biol 18 10 (1998) 1519-1522
5. Leroyer A.S., Isobe H., Lesèche G., Castier Y., Wassef M., Mallat Z., et al. Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques. J Am Coll Cardiol 49 7 (2007) 772-777
6. Mallat Z., Hugel B., Ohan J., Lesèche G., Freyssinet J.M., and Tedgui A. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 99 3 (1999) 348-353
7. Bode A.P., Sandberg H., Dombrose F.A., and Lentz B.R. Association of factor V activity with membranous vesicles released from human platelets: requirement for platelet stimulation. Thromb Res 39 1 (1985) 49-61
8. Sims P.J., Faioni E.M., Wiedmer T., and Shattil S.J. Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity. J Biol Chem 263 34 (1988) 18205-18212
9. Holme P.A., Brosstad F., and Solum N.O. Platelet-derived microvesicles and activated platelets express factor Xa activity. Blood Coagul Fibrinolysis 6 4 (1995) 302-310
10. Scholz T., Temmler U., Krause S., Heptinstall S., and Lösche W. Transfer of tissue factor from platelets to monocytes: role of platelet-derived microvesicles and CD62P. Thromb Haemost 88 6 (2002) 1033-1038
11. George J.N., Pickett E.B., Saucerman S., McEver R.P., Kunicki T.J., Kieffer N., et al. Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. J Clin Invest 78 2 (1986) 340-348
12. Iwamoto S., Kawasaki T., Kambayashi J., Ariyoshi H., and Monden M. Platelet microparticles: a carrier of platelet-activating factor?. Biochem Biophys Res Commun 218 3 (1996) 940-944
13. Mause S.F., von Hundelshausen P., Zernecke A., Koenen R.R., and Weber C. Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arterioscler Thromb Vasc Biol 25 7 (2005) 1512-1518
14. Patsch J.R., Miesenböck G., Hopferwieser T., Mühlberger V., Knapp E., Dunn J.K., et al. Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscler Thromb 12 11 (1992) 1336-1345
15. Boquist S., Ruotolo G., Tang R., Björkegren J., Bond M.G., de Faire U., et al. Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men. Circulation 100 7 (1999) 723-728
16. Zilversmit D.B. Atherogenesis: a postprandial phenomenon. Circulation 60 3 (1979) 473-485
17. Proctor S.D., Vine D.F., and Mamo J.C. Arterial permeability and efflux of apolipoprotein B-containing lipoproteins assessed by in situ perfusion and three-dimensional quantitative confocal microscopy. Arterioscler Thromb Vasc Biol 24 11 (2004) 2162-2167
18. Tushuizen M.E., Nieuwland R., Scheffer P.G., Sturk A., Heine R.J., and Diamant M. Two consecutive high-fat meals affect endothelial-dependent vasodilation, oxidative stress and cellular microparticles in healthy men. J Thromb Haemost 4 5 (2006) 1003-1010
19. Tushuizen M.E., Nieuwland R., Rustemeijer C., Hensgens B.E., Sturk A., Heine R.J., et al. Elevated endothelial microparticles following consecutive meals are associated with vascular endothelial dysfunction in type 2 diabetes. Diabetes Care 30 3 (2007) 728-730
20. Ferreira A.C., Peter A.A., Mendez A.J., Jimenez J.J., Mauro L.M., Chirinos J.A., et al. Postprandial hypertriglyceridemia increases circulating levels of endothelial cell microparticles. Circulation 110 23 (2004) 3599-3603
21. Bröijersen A., Karpe F., Hamsten A., Goodall A.H., and Hjemdahl P. Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation. Atherosclerosis 137 1 (1998) 107-113
22. Nordøy A., Svensson B., and Hansen J.B. Atorvastatin and omega-3 fatty acids protect against activation of the coagulation system in patients with combined hyperlipemia. J Thromb Haemost 1 4 (2003) 690-697
23. Timsit S.G., Sacco R.L., Mohr J.P., Foulkes M.A., Tatemichi T.K., Wolf P.A., et al. Early clinical differentiation of cerebral infarction from severe atherosclerotic stenosis and cardioembolism. Stroke 23 4 (1992) 486-491
24. Grønholdt M.L. Ultrasound and lipoproteins as predictors of lipid-rich, rupture-prone plaques in the carotid artery. Arterioscler Thromb Vasc Biol 19 1 (1999) 2-13
25. Mathiesen E.B., Bønaa K.H., and Joakimsen O. Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the tromso study. Circulation 103 17 (2001) 2171-2175
26. Grønholdt M.L., Nordestgaard B.G., Schroeder T.V., Vorstrup S., and Sillesen H. Ultrasonic echolucent carotid plaques predict future strokes. Circulation 104 1 (2001) 68-73
27. Gray-Weale A.C., Graham J.C., Burnett J.R., Byrne K., and Lusby R.J. Carotid artery atheroma: comparison of preoperative B-mode ultrasound appearance with carotid endarterectomy specimen pathology. J Cardiovasc Surg (Torino) 29 6 (1988) 676-681
28. Fosse E., Johnsen S.H., Stensland-Bugge E., Joakimsen O., Mathiesen E.B., Arnesen E., et al. Repeated visual and computer-assisted carotid plaque characterization in a longitudinal population-based ultrasound study: the Tromso study. Ultrasound Med Biol 32 1 (2006) 3-11
29. Vik A., Mathiesen E.B., Notø A.T., Sveinbjørnsson B., Brox J., and Hansen J.B. Serum osteoprotegerin is inversely associated with carotid plaque echogenicity in humans. Atherosclerosis 191 1 (2006) 128-134
30. El-Barghouty N., Geroulakos G., Nicolaides A., Androulakis A., and Bahal V. Computer-assisted carotid plaque characterisation. Eur J Vasc Endovasc Surg 9 4 (1995) 389-393
31. Elatrozy T., Nicolaides A., Tegos T., and Griffin M. The objective characterisation of ultrasonic carotid plaque features. Eur J Vasc Endovasc Surg 16 3 (1998) 223-230
32. Michelsen A.E., Wergeland R., Stokke O., and Brosstad F. Development of a time-resolved immunofluorometric assay for quantifying platelet-derived microparticles in human plasma. Thromb Res 117 6 (2006) 705-711
33. Mathiesen E.B., Bønaa K.H., and Joakimsen O. Low levels of high-density lipoprotein cholesterol are associated with echolucent carotid artery plaques: the tromso study. Stroke 32 9 (2001) 1960-1965
34. Notø A.T., Mathiesen E.B., Brox J., Björkegren J., and Hansen J.B. Delayed metabolism of postprandial triglyceride-rich lipoproteins in subjects with echolucent carotid plaques. Lipids 43 4 (2008) 353-360
35. Nomura S., Suzuki M., Katsura K., Xie G.L., Miyazaki Y., Miyake T., et al. Platelet-derived microparticles may influence the development of atherosclerosis in diabetes mellitus. Atherosclerosis 116 2 (1995) 235-240
36. de Man F.H., Nieuwland R., van der Laarse A., Romijn F., Smelt A.H., Gevers Leuven J.A., et al. Activated platelets in patients with severe hypertriglyceridemia: effects of triglyceride-lowering therapy. Atherosclerosis 152 2 (2000) 407-414
37. Preston R.A., Jy W., Jimenez J.J., Mauro L.M., Horstman L.L., Valle M., et al. Effects of severe hypertension on endothelial and platelet microparticles. Hypertension 41 2 (2003) 211-217
38. Nomura S., Komiyama Y., Miyake T., Miyazaki Y., Kido H., Suzuki M., et al. Amyloid beta-protein precursor-rich platelet microparticles in thrombotic disease. Thromb Haemost 72 4 (1994) 519-522
39. Patrono C. Aspirin as an antiplatelet drug. N Engl J Med 330 18 (1994) 1287-1294
40. Schwencke C., Schmeisser A., Weinbrenner C., Braun-Dullaeus R.C., Marquetant R., and Strasser R.H. Transregulation of the alpha2-adrenergic signal transduction pathway by chronic beta-blockade: a novel mechanism for decreased platelet aggregation in patients. J Cardiovasc Pharmacol 45 3 (2005) 253-259
41. Puccetti L., Pasqui A.L., Pastorelli M., Bova G., Di Renzo M., Leo A., et al. Platelet hyperactivity after statin treatment discontinuation. Thromb Haemost 90 3 (2003) 476-482
42. Puccetti L., Pasqui A.L., Pastorelli M., Bova G., Cercignani M., Palazzuoli A., et al. Time-dependent effect of statins on platelet function in hypercholesterolaemia. Eur J Clin Invest 32 12 (2002) 901-908
43. Koyama H., Maeno T., Fukumoto S., Shoji T., Yamane T., Yokoyama H., et al. Platelet P-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans. Circulation 108 5 (2003) 524-529
44. Pitsilos S., Hunt J., Mohler E.R., Prabhakar A.M., Poncz M., Dawicki J., et al. Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parameters. Thromb Haemost 90 6 (2003) 1112-1120
45. Coppinger J.A., Cagney G., Toomey S., Kislinger T., Belton O., McRedmond J.P., et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103 6 (2004) 2096-2104
46. De Meyer G.R., De Cleen D.M., Cooper S., Knaapen M.W., Jans D.M., Martinet W., et al. Platelet phagocytosis and processing of beta-amyloid precursor protein as a mechanism of macrophage activation in atherosclerosis. Circ Res 90 11 (2002) 1197-1204
47. Michelsen A.E., Brodin E., Brosstad F., and Hansen J.B. Increased level of platelet microparticles in survivors of myocardial infarction. Scand J Clin Lab Invest, 86 5 (2008) 386-392
48. Heijnen H.F., Schiel A.E., Fijnheer R., Geuze H.J., and Sixma J.J. Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Blood 94 11 (1999) 3791-3799
49. Austin M.A., Hokanson J.E., and Edwards K.L. Hypertriglyceridemia as a cardiovascular risk factor. Am J Cardiol 81 4A (1998) 7B-12B
50. Jeppesen J., Hein H.O., Suadicani P., and Gyntelberg F. Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study. Circulation 97 11 (1998) 1029-1036