Effects of combination treatment with famotidine and methylmethionine sulfonium chloride on the mucus barrier of rat gastric mucosa

Journal of Gastroenterology and Hepatology (Australia)

Volumn 24, Issue 3, 2009, Pages 488-492

  Ichikawa, Takafumi ^b   Ito, Yuko ^a   Saegusa, Yoichi ^c   Iwai, Tomohisa ^c   Goso, Yukinobu ^a,b   Ikezawa, Tomoaki ^c   Ishihara, Kazuhiko ^a  

^a KITASATO UNIVERSITY   (Japan)

^b Departments of Biochemistry   (Japan)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Famotidine; Gastric mucus; Immunohistochemistry; Methylmethionine sulfonium chloride; Mucin biosynthesis

Indexed keywords

FAMOTIDINE; MUCIN; S METHYLMETHIONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; PEPTIC ULCER; PRIORITY JOURNAL; RAT; STOMACH MUCOSA;

EID: 63049096410     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05667.x     Document Type: Article

References (28)

1. Hagiwara T, Mukaisho K, Ling ZQ, Sakano T, Sugihara H, Hattori T. Rebamipide contributes to reducing adverse effects of long-term administration of omeprazole in rats. Dig. Dis. Sci. 2007 52 : 988 94.
2. Kinoshita M, Noto T, Tamaki H. Effect of a combination of ecabet sodium and cimetidine on experimentally induced gastric lesions and gastric mucosal resistance to ulcerogenic agents in rats. Biol. Pharm. Bull. 1995 18 : 223 6.
3. Murata H, Kawano S, Tsuji S et al. Combination therapy of ecabet sodium and cimetidine compared with cimetidine alone for gastric ulcer: prospective randomized multicenter study. J. Gastroenterol. Hepatol. 2003 18 : 1029 33.
4. Murata H, Kawano S, Tsuji S et al. Combination of enprostil and cimetidine is more effective than cimetidine alone in treating gastric ulcer: prospective multicenter randomized controlled trial. Hepatogastroenterology 2005 52 : 1925 9.
5. Terano A, Arakawa T, Sugiyama T et al. A pilot study to evaluate a new combination therapy for gastric ulcer: Helicobacter pylori eradication therapy followed by gastroprotective treatment with rebamipide. J. Gastroenterol. Hepatol. 2006 21 : 103 9.
6. Houston LJ, Mills JG, Wood JR. Does co-prescription of sucralfate with ranitidine therapy enhance the healing of gastric ulcers? Am. J. Gastroenterol. 1993 88 : 675 9.
7. Allen A, Flemström G. Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin. Am. J. Physiol. 2005 288 : C1 19.
8. Ichikawa T, Ishihara K, Saigenji K, Hotta K. Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the rat stomach. Eur. J. Pharmacol. 1994 251 : 107 11.
9. 2 receptor antagonist, FRG-8813, on gastric mucin in rats with or without acidified ethanol-induced gastric damage. Life Sci. 1994 54 : PL159 64.
10. 2-receptor antagonist, lafutidine, on the mucus barrier of human gastric mucosa. J. Gastroenterol. Hepatol. 2007 22 : 1800 5.
11. Ishihara K, Kurihara M, Goso Y, Ota H, Katsuyama T, Hotta K. Establishment of monoclonal antibodies against carbohydrate moiety of gastric mucins distributed in the different sites and layers of rat gastric mucosa. Glycoconj. J. 1996 13 : 857 64.
12. Salim AS. Protection against chronic gastric ulceration in the rat with sulfhydryl-containing agents. J. Pharm. Sci. 1992 81 : 698 700.
13. Salim AS. Role of sulfhydryl-containing agents in the healing of erosive gastritis and chronic gastric ulceration in the rat. J. Pharm. Sci. 1992 81 : 70 3.
14. Watanabe T, Ohara S, Ichikawa T, Saigenji K, Hotta K. Mechanisms for cytoprotection by vitamin U from ethanol-induced gastric mucosal damage in rats. Dig. Dis. Sci. 1996 41 : 49 54.
15. Watanabe T, Ohara S, Miyazawa S, Saigenji K, Hotta K. Augmentative effects of L-cysteine and methylmethionine sulfonium chloride on mucin secretion in rabbit gastric mucous cells. J. Gastroenterol. Hepatol 2000 15 : 45 52.
16. Hotta K, Ohara S, Ishihara K et al. Relation between gastric acid secretion and gastric mucous glycoproteins. In : Nagao F, Matsuo Y, Kasuya Y, Tsuchiya M, eds. Gastrointestinal Function: Regulation and Disturbances, vol. 7. Tokyo : Excerpta Medica, 1989 101 14.
17. 2 release in the rat stomach. Aliment. Pharmacol. Ther. 1996 10 : 111 17.
18. Azuumi Y, Ohara S, Ishihara K, Okabe H, Hotta K. Correlation of quantitative changes of gastric mucosal glycoproteins with aspirin-induced gastric damage in rats. Gut 1980 21 : 533 6.
19. Ota H, Katsuyama T. Alternating laminated array of two types of mucin in the human gastric surface mucous layer. Histochem. J. 1992 24 : 86 92.
20. 2-receptor antagonist famotidine in the rat: comparison with ranitidine. Br. J. Pharmacol. 1987 92 : 153 9.
21. Miyata K, Kamato T, Nishida A, Honda K. Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn. J. Pharmacol. 1991 55 : 211 22.
22. 2-blocker, 3-[[[[2-(diaminomethylene)amino]-4-thiazolyl]methyl ]thio]-N2-sulfamoyl propionamidine (YM-11170), on gastric secretion, ulcer formation and weight of male accessory sex organs in rats. Arzneimittelforschung 1982 32 : 734 7.
23. Sheahan DG, Jervis HR. Comparative histochemistry of gastrointestinal mucosubstances. Am. J. Anat. 1976 146 : 103 31.
24. Ishihara K, Kurihara M, Goso Y et al. Peripheral alpha-linked N-acetylglucosamine on the carbohydrate moiety of mucin derived from mammalian gastric gland mucous cells: epitope recognized by a newly characterized monoclonal antibody. Biochem. J. 1996 318 : 409 16.
25. Kawakubo M, Ito Y, Okimura Y et al. Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection. Science 2004 305 : 1003 6.
26. Sawaguchi A, Ishihara K, Kawano J, Oinuma T, Hotta K, Suganuma T. Fluid dynamics of the excretory flow of zymogenic and mucin contents in rat gastric gland processed by high-pressure freezing/freeze substitution. J. Histochem. Cytochem. 2002 50 : 223 34.
27. Guslandi M, Battaglia A, Pamparana F, Passaretti S, Pellegrini A, Tittobello A. Weakening effect of famotidine but not of nizatidine on the mucus-bicarbonate barrier of the human stomach. Drugs Exp. Clin. Res. 1990 16 : 481 5.
28. Seri K, Amemiya K, Sugimoto H, Kato T. Effects of S-methylmethionine (vitamin U) on experimental nephrotic hyperlipidemia. Arzneimittelforschung 1979 29 : 1517 20.